Using Primates In Medical Research

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Nonhuman Primates in Biomedical Research

Author : Christian R. Abee
Publisher : Academic Press
ISBN 13 : 0123978386
Total Pages : 867 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Nonhuman Primates in Biomedical Research by : Christian R. Abee

Download or read book Nonhuman Primates in Biomedical Research written by Christian R. Abee and published by Academic Press. This book was released on 2012-06-07 with total page 867 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in bioledical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information Includes four color images throughout

Chimpanzees in Research

Author : Committee on Long-Term Care of Chimpanzees
Publisher : National Academies Press
ISBN 13 : 0309591155
Total Pages : 108 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis Chimpanzees in Research by : Committee on Long-Term Care of Chimpanzees

Download or read book Chimpanzees in Research written by Committee on Long-Term Care of Chimpanzees and published by National Academies Press. This book was released on 1997-09-01 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chimpanzees in biomedical and behavioral research constitute a national resource that has been valuable in addressing national health needs. Facilities that house chimpanzees owned and supported by the National Institutes of Health (NIH) have successfully met the research requirements of the scientific community. The captive chimpanzee population in the United States has grown substantially, particularly over the last decade. That growth is due primarily to the success of the NIH-sponsored Chimpanzee Breeding and Research Program, which achieved the birth numbers thought necessary to meet the projected needs of biomedical research. However, the expected level of use of the chimpanzee model in biomedical research did not materialize, and that has created a complex problem that threatens both the availability of chimpanzees for research in the future and the infrastructure required to ensure the well-being of captive chimpanzees used in biomedical research. Because the present system is fragmented, it is impossible to formulate an accurate overview of the size and nature of the chimpanzee population. But, if the chimpanzee is to continue to be used in biomedical research responsibly, effectively, and cost-effectively, we must be able to oversee, track, and coordinate the maintenance and use of chimpanzees and to control the size of the population. To assess the long-range situation and to develop, implement, and monitor the application of policies for the proper use and care of chimpanzees, an authoritative, centralized oversight structure is imperative. Once it is in place, it will be possible to refine and implement this report's recommendations.

Occupational Health and Safety in the Care and Use of Nonhuman Primates

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309167949
Total Pages : 180 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Occupational Health and Safety in the Care and Use of Nonhuman Primates by : National Research Council

Download or read book Occupational Health and Safety in the Care and Use of Nonhuman Primates written by National Research Council and published by National Academies Press. This book was released on 2003-06-13 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.

Ethics Dumping

Author : Doris Schroeder
Publisher : Springer
ISBN 13 : 3319647318
Total Pages : 144 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Ethics Dumping by : Doris Schroeder

Download or read book Ethics Dumping written by Doris Schroeder and published by Springer. This book was released on 2017-12-04 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides original, up-to-date case studies of “ethics dumping” that were largely facilitated by loopholes in the ethics governance of low and middle-income countries. It is instructive even to experienced researchers since it provides a voice to vulnerable populations from the fore mentioned countries. Ensuring the ethical conduct of North-South collaborations in research is a process fraught with difficulties. The background conditions under which such collaborations take place include extreme differentials in available income and power, as well as a past history of colonialism, while differences in culture can add a new layer of complications. In this context, up-to-date case studies of unethical conduct are essential for research ethics training.

Chimpanzees in Biomedical and Behavioral Research

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309220424
Total Pages : 200 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Chimpanzees in Biomedical and Behavioral Research by : National Research Council

Download or read book Chimpanzees in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2011-12-05 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.

Nonhuman Primates in Biomedical Research

Author : Christian R. Abee
Publisher : Academic Press
ISBN 13 : 0123813662
Total Pages : 868 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Nonhuman Primates in Biomedical Research by : Christian R. Abee

Download or read book Nonhuman Primates in Biomedical Research written by Christian R. Abee and published by Academic Press. This book was released on 2012-03-29 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, up-to-date review of the use of nonhuman primates in biomedical research, emphasising the biology and management, diseases, and biomedical models for nonhuman primate species most commonly used in research.

Use of Laboratory Animals in Biomedical and Behavioral Research

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309038391
Total Pages : 113 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Use of Laboratory Animals in Biomedical and Behavioral Research by : National Research Council

Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Nonhuman Primates in Biomedical Research

Author : Christian R. Abee
Publisher : Academic Press
ISBN 13 : 0123978378
Total Pages : 537 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Nonhuman Primates in Biomedical Research by : Christian R. Abee

Download or read book Nonhuman Primates in Biomedical Research written by Christian R. Abee and published by Academic Press. This book was released on 2012-05-09 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Now in four color throughout, making the book more visually stimulating to enhance learning and ease of use Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in biomedical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information

Nonhuman Primates and Medical Research

Author : Geoffrey H. Bourne
Publisher : Academic Press
ISBN 13 : 1483258041
Total Pages : 554 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Nonhuman Primates and Medical Research by : Geoffrey H. Bourne

Download or read book Nonhuman Primates and Medical Research written by Geoffrey H. Bourne and published by Academic Press. This book was released on 2014-05-10 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonhuman Primates and Medical Research focuses on the contributions of nonhuman primates to biomedical research. The selection first elaborates on monkeys and yellow fever, cell cultures, and tuberculosis and bacterial infection. Discussions focus on bacterial diseases, tuberculosis, radiobiology, antibody formation and pharmacologic studies, cell-culture media and methods, the rhesus monkey and early history of yellow fever research, and monkeys and yellow fever in the future. The text then elaborates on virus research, models for investigation in parasitology, and primates as organ donors in transplantation studies in man. The manuscript examines the importance of monkeys for the study of malignant tumors in man; use of primates in cardiovascular research; and humanlike diseases in anthropoid apes. Topics include etiology of humanlike disease in anthropoid apes, atherosclerosis, historical aspects of primate research, selection of a suitable primate, and preeclampsia. The text also ponders on primate studies and human evolution and mental retardation. The selection is a valuable reference for researchers interested in the contributions of nonhuman primates to biomedical research.

Resource Sharing in Biomedical Research

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309055822
Total Pages : 105 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Resource Sharing in Biomedical Research by : Institute of Medicine

Download or read book Resource Sharing in Biomedical Research written by Institute of Medicine and published by National Academies Press. This book was released on 1996-12-29 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States is entering an era when, more than ever, the sharing of resources and information might be critical to scientific progress. Every dollar saved by avoiding duplication of efforts and by producing economies of scale will become increasingly important as federal funding enters an era of fiscal restraint. This book focuses on six diverse case studies that share materials or equipment with the scientific community at large: the American Type Culture Collection, the multinational coordinated Arabidopsis thaliana Genome Research Project, the Jackson Laboratory, the Washington Regional Primate Research Center, the Macromolecular Crystallography Resource at the Cornell High-Energy Synchrotron Source, and the Human Genome Center at Lawrence Livermore National Laboratory. The book also identifies common strengths and problems faced in the six cases, and presents a series of recommendations aimed at facilitating resource sharing in biomedical research.

The Laboratory Nonhuman Primate

Author : Jeffrey D. Fortman
Publisher : CRC Press
ISBN 13 : 1351643274
Total Pages : 328 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis The Laboratory Nonhuman Primate by : Jeffrey D. Fortman

Download or read book The Laboratory Nonhuman Primate written by Jeffrey D. Fortman and published by CRC Press. This book was released on 2017-10-23 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key features Contains 28 updated tables designed as quick, easy-to-use references for New and Old World species Provides over 100 photographs and illustrations, most now in color, depicting aspects of nonhuman primate biology, behavior, management practices, diseases, and technical procedures Gives a concise overview of regulatory considerations for the use of nonhuman primates in biomedical research Expands the Veterinary Care chapter to include new sections on nutritional support, behavioral conditions, dental care, and updated information on anesthetic and analgesic drugs Presents step-by-step descriptions of common and advanced sampling techniques Includes extensive resource lists for vendors of animals, feed, sanitation supplies, caging, anesthetic equipment, and veterinary and research supplies Extensively updated to include current literature, The Laboratory Nonhuman Primate, Second Edition, continues to serve as a quick reference source for technicians, caretakers, veterinarians, researchers, and students working with primates in biomedical research. It provides details on basic husbandry and covers biologic characteristics, regulatory compliance, common diseases, and anesthetic management. The text gives easy-to-follow descriptions of basic technical procedures including restraint, intubation, tuberculin skin testing, and collection of blood and urine samples. It also reviews advanced sampling procedures including collection of bone marrow, cerebrospinal fluid, bronchoalveolar lavage fluid, and rectal mucosal biopsy. The Laboratory Nonhuman Primate presents information in a clear, concise format to allow readers to incorporate concepts and techniques into the standard operating procedures of a facility.

Laboratory Primate Handbook

Author : Robert A. Jr. Whitey
Publisher : Academic Press
ISBN 13 :
Total Pages : 192 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Laboratory Primate Handbook by : Robert A. Jr. Whitey

Download or read book Laboratory Primate Handbook written by Robert A. Jr. Whitey and published by Academic Press. This book was released on 1973-01-28 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Primate Handbook deals with the proper care and handling, treatment, and transportation of nonhuman primates to be used as research subjects in a laboratory environment. It considers the protection of human and animal health, identification, procurement, and husbandry, as well as compliance with federal regulations. Organized into 10 chapters, this volume begins with an overview of living primates and their classification, followed by procurement and production for biomedical research purposes. It then discusses housing and care of primates; preventive medicine and public health programs aimed at minimizing the hazards that may arise from diseases transmissible between nonhuman primates and man; and restraint and special techniques, including anesthetics and pre-anesthetics. The book also covers nutrition for primates and prevention of nutritional diseases, as well as generalized infectious diseases; parasites that cause disease in primates; and collection of physiological data on primates. Finally, the book looks at federal regulations and policies governing the humane care and treatment of nonhuman primates used in research. This book will benefit biomedical researchers involved in laboratory studies of nonhuman primates.

Primate Models of Children's Health and Developmental Disabilities

Author : Thomas Burbacher
Publisher : Academic Press
ISBN 13 : 0080554067
Total Pages : 480 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Primate Models of Children's Health and Developmental Disabilities by : Thomas Burbacher

Download or read book Primate Models of Children's Health and Developmental Disabilities written by Thomas Burbacher and published by Academic Press. This book was released on 2011-10-10 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rate of neurodevelopmental disabilities, including autism, mental retardation, hearing loss and attention deficit hyperactivity disorder is rising in the United States. Although estimates of the prevalence of these disorders vary, figures from the CDC indicate that 4% of all school age children are developmentally disabled. During infancy, many important milestones in behavioral development are shared between human and nonhuman primates. Learning more about the causes of abnormal development in monkeys has provided important insights into the mechanisms underlying neurodevelopmental disabilities in human infants. This book documents the latest research not commonly found in other references, and provides a comprehensive look at the results from decades of work with nonhuman primates as it relates to child development and disability. Includes hot topics such as early chemical exposures, immunological influences on development, low birth weight, endocrine disrupters, pediatric AIDS, origin of childhood psychopathologies and assisted reproductive technology Represents the significant body of work accumulated since funding for research on developmental disabilities has increased substantially in recent years

Animal Experimentation: Working Towards a Paradigm Change

Author : Kathrin Herrmann
Publisher : BRILL
ISBN 13 : 9004391193
Total Pages : 749 pages
Book Rating : 4.0/5 (43 download)

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Book Synopsis Animal Experimentation: Working Towards a Paradigm Change by : Kathrin Herrmann

Download or read book Animal Experimentation: Working Towards a Paradigm Change written by Kathrin Herrmann and published by BRILL. This book was released on 2019-04-30 with total page 749 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.

Occupational Health and Safety in the Care and Use of Research Animals

Author : Committee on Occupational Safety and Health in Research Animal Facilities
Publisher : National Academies Press
ISBN 13 : 0309520398
Total Pages : 167 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis Occupational Health and Safety in the Care and Use of Research Animals by : Committee on Occupational Safety and Health in Research Animal Facilities

Download or read book Occupational Health and Safety in the Care and Use of Research Animals written by Committee on Occupational Safety and Health in Research Animal Facilities and published by National Academies Press. This book was released on 1997-06-23 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much has been written about the care of research animals. Yet little guidance has appeared on protecting the health and safety of the people who care for or use these animals. This book, an implementation handbook and companion to Guide For the Care and Use of Laboratory Animals, identifies principles for building a program and discusses the accountability of institutional leaders, managers, and employees for a program's success. It provides a detailed description of risks-- physical and chemical hazards, allergens and zoonoses, and hazards from experiments--which will serve as a continuing reference for the laboratory. The book offers specific recommendations for controlling risk through administrative procedures, facility design, engineering controls, and periodic evaluations. The volume focuses on the worker, with detailed discussions of work practices, the use of personal protective gear, and the development of an emergency response plan. This handbook will be invaluable to administrators, researchers, and employees in any animal research facility. It will also be of interest to personnel in zoos, animal shelters, and veterinary facilities.

Essentials of Laboratory Animal Science: Principles and Practices

Author : P. Nagarajan
Publisher : Springer Nature
ISBN 13 : 981160987X
Total Pages : 797 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Essentials of Laboratory Animal Science: Principles and Practices by : P. Nagarajan

Download or read book Essentials of Laboratory Animal Science: Principles and Practices written by P. Nagarajan and published by Springer Nature. This book was released on 2021-07-23 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.

Nonhuman Primates in Biomedical Research,Two Volume Set

Author : Christian R. Abee
Publisher : Academic Press
ISBN 13 : 0124159729
Total Pages : 3435 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Nonhuman Primates in Biomedical Research,Two Volume Set by : Christian R. Abee

Download or read book Nonhuman Primates in Biomedical Research,Two Volume Set written by Christian R. Abee and published by Academic Press. This book was released on 2012-12-31 with total page 3435 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The publication emphasizes the biology and management, diseases, and biomedical models for nonhuman primate species most commonly used in research. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Now in four color throughout, making the book more visually stimulating to enhance learning and ease of use Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in biomedical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information