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Understanding Breast Cancer Genetics
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Book Synopsis Understanding Breast Cancer Genetics by : Barbara T. Zimmerman
Download or read book Understanding Breast Cancer Genetics written by Barbara T. Zimmerman and published by Univ. Press of Mississippi. This book was released on 2009-09-18 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book by a scientist whose background is in cellular and molecular biology examines the fearsome disease that strikes one in eight women in the United States. Although women are more likely to die of heart disease or of lung cancer, a diagnosis of breast cancer is the medical pronouncement that a woman is most likely to fear. It kills more than 40,000 Americans annually. Why are some women more vulnerable than others? The interplay between genetics and environment is suspected. Thus this book for general readers will help them understand the genetic basis of both sporadic and inherited breast cancers. Although only five to ten percent of breast cancer patients have inherited mutations in these genes, all women need to understand the genetic implications of the disease. In clear, concise language Barbara T. Zimmerman guides the reader through the complexities, discussing in detail the genes that are known to increase susceptibility and the ways they are passed on. Examining the general biology of breast cancer, Zimmerman describes how sporadic and inherited forms of the disease arise and how the location of the tumors can affect the body. She discusses genetic mutations and their roles in the development of tumors and tells how these potentially cancer-inducing genes were discovered. Covered too are the issues of risk, prevention, screening, diagnosis, therapy, and genetic testing and counseling. Zimmerman concludes with a comprehensive analysis of current research and with an emphasis on how a woman's understanding of inherited breast cancer can help doctors seeking to design better methods for prevention and therapy. A useful list of resources for further information about the genetic causes of breast cancer is included.
Book Synopsis The Role of Genetics in Breast and Reproductive Cancers by : Piri Welcsh
Download or read book The Role of Genetics in Breast and Reproductive Cancers written by Piri Welcsh and published by Springer Science & Business Media. This book was released on 2009-10-03 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.
Book Synopsis Understanding BRCA by : Clarissa Foster
Download or read book Understanding BRCA written by Clarissa Foster and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Do you have a close relative who has died from, or is experiencing, aggressive breast, ovarian or prostate cancer? Have they been tested for the BRCA gene mutation? Have you? At the age of 35 and following the death of her mother from ovarian cancer, Clarissa Foster was found to carry a harmful mutation in the BRCA2 gene which drastically increased her risk of developing breast and ovarian cancer. She searched for a book that would help her to understand the full extent of what it meant to carry a harmful mutation, the options available to her to lower her risk and, most importantly, how it would feel to undergo risk-reducing surgery. Finding nothing that answered her needs, she set about reading all the available medical literature and liaising with relevant medical professionals to answer her questions. This book is the result of that research and of the decision she took based on it – to have a bilateral mastectomy and salpingo-oophorectomy. Within the context of her own painful experience of family cancer and of elective surgery, Clarissa explains what the BRCA mutation is, what it signifies, what the individual’s choices are and what the fall out can be in terms of a woman’s body image, identity and sexual functioning."--Publisher's description.
Download or read book Breast Cancer written by Anne M. Bowcock and published by Springer Science & Business Media. This book was released on 1999-01-11 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive state-of-the-art summary of breast cancer research and treatment by leading authorities. The book's many distinguished contributors illuminate the biology and genetics of breast cancer, including what is known about the hereditary breast cancer genes, BRCA1 and 2, the cutting-edge cytogenic approaches, and the biology of breast cancer metastasis. In addition, the authors describe current and future methods of breast cancer treatment in depth, and discuss environment and diet as risk factors for the disease. Breast Cancer: Molecular Genetics, Pathogenesis, and Therapeutics constitutes an excellent reference and resource for all those clinical and experimental oncologists, as well as genetic counselors nurses, who need to understand the latest developments in breast cancer biology, risk, and treatment.
Book Synopsis The Role of Genetics in Breast and Reproductive Cancers by : Piri Welcsh
Download or read book The Role of Genetics in Breast and Reproductive Cancers written by Piri Welcsh and published by Springer. This book was released on 2009-11-05 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.
Book Synopsis Breast Cancer Genes and the Gendering of Knowledge by : Sahra Gibbon
Download or read book Breast Cancer Genes and the Gendering of Knowledge written by Sahra Gibbon and published by Palgrave Macmillan. This book was released on 2007-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book examines the social and cultural context of new genetic knowledge associated with breast cancer. It looks at how this knowledge and technologies are used and received in two contrasting social arenas - cancer genetic clinics and a breast cancer research charity.
Book Synopsis Principles of Clinical Cancer Genetics by : Daniel C. Chung
Download or read book Principles of Clinical Cancer Genetics written by Daniel C. Chung and published by Springer Science & Business Media. This book was released on 2010-07-20 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.
Book Synopsis Genetics for Health Professionals in Cancer Care by : Chris Jacobs
Download or read book Genetics for Health Professionals in Cancer Care written by Chris Jacobs and published by OUP Oxford. This book was released on 2014-08-14 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of genetics is becoming increasingly important in all aspects of healthcare and particularly in the field of cancer care. Genetics for Health Professionals in Cancer Care: From Principles to Practice equips health professionals with the knowledge and skills required for all aspects of managing cancer family history. This includes taking an accurate cancer family history and drawing a family tree; understanding cancer biology, basic cancer genetics and the genes involved in hereditary breast, ovarian, prostate, colorectal, gastric and related gynaecological cancers and rare cancer predisposing syndromes; assessing cancer risk and communicating risk information; early detection and risk reducing measures available for those at increased risk and managing individuals with hereditary cancer. Drawing on experiences of health professionals, Genetics for Health Professionals in Cancer Care discusses the challenges raised and provides practical advice and insight into what happens when a patient is referred for genetic counselling and genetic testing, including the psychological, social and ethical issues faced by individuals and families with and at risk of hereditary cancer. The book also provides practical guidance on setting up a cancer family history clinic in primary and secondary care. Genetics for Health Professionals in Cancer Care is essential reading for healthcare professionals working with cancer patients and their families, and is an ideal reference text for non-specialists working in cancer genetics.
Book Synopsis Molecular Markers in Hereditary Breast Cancer by :
Download or read book Molecular Markers in Hereditary Breast Cancer written by and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The promise of research into breast cancer genetics is that it will provide us with new insights into the etiology of breast cancer that can be translated to strategies for early diagnosis and treatment for the larger population of women who develop breast cancer without having a genetic predisposition. An academic award represents an outstanding opportunity for me to critically appraise the emerging role of genetics in clinical breast cancer care and forge new avenues of research. Toward this goal, I plan to accomplish the following during the award period: (1) perform a thorough review of the cytogenetic and molecular genetics literature to identify potential chromosomal regions that may harbor genes whose abnormal function is critically involved in the development of breast cancer. (2) develop a robust panel of markers that can be used for clinical correlative studies of hereditary breast cancers. (3) develop a tissue repository composed of biological specimens from 500 patients with inherited breast cancer (e.g fresh frozen tumor specimens, or paraffin embedded tumor specimens and normal blood lymphocytes, DNA and sera whenever possible). These studies will lead to an improved understanding of the biology of breast cancer which will ultimately translate into more effective therapies.
Book Synopsis Understanding Breast Cancer by : Marvin A. Rich
Download or read book Understanding Breast Cancer written by Marvin A. Rich and published by . This book was released on 1983 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Genetics and Epigenetics of Breast Cancer by : Madhumita Roy
Download or read book Genetics and Epigenetics of Breast Cancer written by Madhumita Roy and published by Springer Nature. This book was released on 2023-05-10 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the contribution of genetics and epigenetics alterations in the initiation, development, and recurrence of breast cancer. It also reviews the potential of translating the epigenetic alterations into diagnosis, prognosis, and breast cancer therapy. The initial chapters explore the epigenetics, etiology, and conventional treatment strategies for breast cancer. The subsequent chapters discuss the genetic landscape and cover three main epigenetic modulation mechanisms; histone modification, DNA methylation, and miRNA silencing. Further, the book explores the potential of epigenetic drugs in treating breast cancer. Lastly, it covers the phytochemicals targeting epigenetic modulators in breast cancer treatment. This book is an essential source for researchers and practitioners interested in exploring the potential of epigenetics modulators in breast cancer treatment.
Book Synopsis Encyclopedia of Human Genetics and Disease [2 volumes] by : Evelyn B. Kelly
Download or read book Encyclopedia of Human Genetics and Disease [2 volumes] written by Evelyn B. Kelly and published by Bloomsbury Publishing USA. This book was released on 2013-01-07 with total page 1149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume encyclopedia examines the history, characteristics, causes, and treatment of genetic disease, as well as the science of genetics itself. Modern science has unlocked many of the mysteries of genetics, providing a blueprint for understanding the origins behind previously mysterious ailments and conditions, both common and uncommon. A complete understanding remains elusive, however: geneticists are still refining theories about what causes chromosomes to mutate, and genetic diseases remain difficult to diagnose and challenging to treat. This fascinating reference explores the scientific and human aspects of this complex field of science. Encyclopedia of Human Genetics and Disease features nearly 400 entries, including well-known genetic diseases, rare and lesser-known genetic diseases, and the genetic factors that may contribute to common diseases and health conditions, such as breast cancer and obesity. The author presents in-depth discussions of concepts essential to understanding genetic disease in 18 entries that provide background on key topics, such as "Genetics 101," the genome and the foundations of genetics, genetic counseling, and newborn screening. Each of the 355 disorders profiled provides the history of the condition, its prevalence, causes, treatment (if any), and further reading. Interesting sidebars and compelling photos that help inform content accompany many entries.
Book Synopsis Genetic Counseling in Breast Cancer by : Beth N. Peshkin
Download or read book Genetic Counseling in Breast Cancer written by Beth N. Peshkin and published by IOS Press. This book was released on 2007 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: A testament to how far the field of genetic counseling for breast cancer susceptibility has advanced since the mid-1990s, following the cloning of two major breast (and ovarian) cancer susceptibility genes, BRCA1 and BRCA2.
Book Synopsis Cancer Genetics and Psychotherapy by : Parvin Mehdipour
Download or read book Cancer Genetics and Psychotherapy written by Parvin Mehdipour and published by Springer. This book was released on 2017-09-20 with total page 1170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide the readers with the most comprehensive and latest accounts of research and development in this field by emphasizing on the manner of relation between doctors and cancer patients in direction of improving the patients’ style of life. This book, partly, will deal with psychotherapy by considering cancer patients, benefits, hazards and also social impacts including life style. The social supports as the key and influential paradigms will be challenged as a comparative insight by considering the global unity in order to provide a reasonable model to improve the interaction between cancer and psychological nest. In this book, the real stories of cancer patient will be also provided. The initial insight of sections includes: 1) Brief classifications and key points of clinical and histopatological aspects of each organ. 2) Brief view of genetic alterations in each organ. 3) Therapeutic aspects. 4) Brief classifications and key points of Psychology in cancer. 5) The interactions of clinical aspects with psychological field.
Book Synopsis Accomplishments, Collaborative Projects and Future Initiatives in Breast Cancer Genetic Predisposition by : Paolo Peterlongo
Download or read book Accomplishments, Collaborative Projects and Future Initiatives in Breast Cancer Genetic Predisposition written by Paolo Peterlongo and published by Frontiers Media SA. This book was released on 2019-10-16 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this eBook, we described the accomplishments, collaborative projects and future initiatives in the field of breast cancer genetic predisposition. More specifically, the articles included focused on aspects such as mutation screening in unexplored populations, identification and characterization of novel predisposing genes and mutations, and population screening.
Download or read book Breast Cancer written by Umberto Veronesi and published by Springer. This book was released on 2017-11-03 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with up-to-date information on important advances in the understanding of breast cancer and innovative approaches to its management. Current and emerging perspectives on genetics, biology, and prevention are first discussed in depth, and individual sections are then devoted to pathology, imaging, oncological surgery, plastic and reconstructive surgery, medical oncology, and radiotherapy. In each case the focus is on the most recent progress and/or state of the art therapies and techniques. Further topics to receive detailed consideration include particular conditions requiring multidisciplinary approaches, the investigation of new drugs and immunological agents, lifestyle and psychological aspects, and biostatistics and informatics. The book will be an excellent reference for practitioners, interns and residents in medical oncology, oncologic surgery, radiotherapy, pathology, and human genetics, researchers, and advanced medical students.
Book Synopsis Journal of the National Cancer Institute by :
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1998 with total page 1030 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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