The Clinical Neurobiology Of The Hippocampus

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The Clinical Neurobiology of the Hippocampus

Author : Thorsten Bartsch
Publisher : OUP Oxford
ISBN 13 : 0191628964
Total Pages : 336 pages
Book Rating : 4.1/5 (916 download)

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Book Synopsis The Clinical Neurobiology of the Hippocampus by : Thorsten Bartsch

Download or read book The Clinical Neurobiology of the Hippocampus written by Thorsten Bartsch and published by OUP Oxford. This book was released on 2012-07-26 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of the most studied structures in the human brain and plays a pivotal role in human memory function. Its recognized function is reflected by the presence of an extensive body of neurophysiological, neuropsychological, anatomical and neurocomputational literature that presents basic mechanisms, theoretical models and psychological concepts. However, in the rapidly growing field of hippocampal research, the clinical aspects of diseases that affect the hippocampus are greatly under-represented in current literature, and clinical approaches and concepts are scattered throughout various clinical and basic scientific disciplines. The Clinical Neurobiology of the Hippocampus explores clinical approaches to the range of diseases that affect the hippocampus. It brings together and reviews the common methods, clinical findings, concepts, mechanisms and, where applicable, therapeutic strategies for these clinical approaches. The clinical spectrum of hippocampal dysfunction encompasses a wide range of neurological, behavioural and psychiatric symptoms and surpasses the ability to encode, store and retrieve information. The relevance of hippocampal involvement in clinical diseases goes beyond mere neuropsychological deficits and includes psychopathological states in various conditions, such as acute amnesic syndromes, Alzheimer's disease, temporal lobe epilepsy (TLE), sleep, stroke medicine, limbic encephalitis, neurodevelopmental disorders, stress- and trauma-related disorders, depression, and schizophrenia. The first part of the book covers the basic and integrative features of the hippocampus, such as the anatomy and imaging of this structure, and the basic mechanisms of hippocampal function, including the principles of hippocampus-dependent memory processing in amnesia and sleep, the mechanisms of vulnerability and adult neurogenesis as well as the effects of stress. The second part covers the various clinical manifestations in which the hippocampus is involved and in which the preceding basic mechanisms are reflected. Bringing together a broad team of experts on the basic and clinical aspects of the hippocampus, the book provides an integrative view of the hippocampus. It is invaluable for neurologists, neuroscientists, and psychiatrists, and will stimulate interdisciplinary discussions in clinical neuroscience.

The Hippocampus in Clinical Neuroscience

Author : K. Szabo
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318025682
Total Pages : 174 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis The Hippocampus in Clinical Neuroscience by : K. Szabo

Download or read book The Hippocampus in Clinical Neuroscience written by K. Szabo and published by Karger Medical and Scientific Publishers. This book was released on 2014-04-23 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of the most intriguing structures of the human brain. Damage to this part causes symptoms ranging from transient disorders accompanied by tiny lesions to severely debilitating cognitive disorders with marked tissue loss. This publication provides a predominantly clinical approach to the complex workings of the hippocampus from different perspectives, ranging from basic principles to specific diseases. The first part of the book summarizes current knowledge regarding the structure and physiology of the hippocampus and establishes the ties to basic neuroscience. The second part deals with the function and assessment of the human hippocampus, including memory function, neuropsychological measures, and conventional and functional imaging studies. The chapters of the third part are devoted to the hippocampus in neurological disorders, e.g. the interaction between stress and memory function, and the pathological conditions of common as well as selected rare neurological diseases affecting the hippocampus. The book is highly recommended to clinical neurologists who wish to gain a broad understanding of this complex and fascinating organ in terms of basic principles, modern imaging findings, and specific diseases.

The Hippocampus Book

Author : Per Andersen
Publisher : Oxford University Press
ISBN 13 : 9780195100273
Total Pages : 892 pages
Book Rating : 4.1/5 (2 download)

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Book Synopsis The Hippocampus Book by : Per Andersen

Download or read book The Hippocampus Book written by Per Andersen and published by Oxford University Press. This book was released on 2007 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.

Discovering the Brain

Author : National Academy of Sciences
Publisher : National Academies Press
ISBN 13 : 0309045290
Total Pages : 195 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Discovering the Brain by : National Academy of Sciences

Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Gateway to Memory

Author : Mark A. Gluck
Publisher : MIT Press
ISBN 13 : 9780262571524
Total Pages : 470 pages
Book Rating : 4.5/5 (715 download)

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Book Synopsis Gateway to Memory by : Mark A. Gluck

Download or read book Gateway to Memory written by Mark A. Gluck and published by MIT Press. This book was released on 2001 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is for students and researchers who have a specific interest in learning and memory and want to understand how computational models can be integrated into experimental research on the hippocampus and learning. It emphasizes the function of brain structures as they give rise to behavior, rather than the molecular or neuronal details. It also emphasizes the process of modeling, rather than the mathematical details of the models themselves. The book is divided into two parts. The first part provides a tutorial introduction to topics in neuroscience, the psychology of learning and memory, and the theory of neural network models. The second part, the core of the book, reviews computational models of how the hippocampus cooperates with other brain structures -- including the entorhinal cortex, basal forebrain, cerebellum, and primary sensory and motor cortices -- to support learning and memory in both animals and humans. The book assumes no prior knowledge of computational modeling or mathematics. For those who wish to delve more deeply into the formal details of the models, there are optional "mathboxes" and appendices. The book also includes extensive references and suggestions for further readings.

Neurogenesis in the Adult Brain I

Author : Tatsunori Seki
Publisher : Springer Science & Business Media
ISBN 13 : 4431539336
Total Pages : 415 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Neurogenesis in the Adult Brain I by : Tatsunori Seki

Download or read book Neurogenesis in the Adult Brain I written by Tatsunori Seki and published by Springer Science & Business Media. This book was released on 2011-06-15 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of adult neurogenesis caused a paradigm shift in the neurosciences. For more than 100 years, it was believed that adult neurons do not regenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed the course of history. Their research, included here, provides the foundations of the field. Today, adult neurogenesis is a rapidly expanding discipline applicable to the study of brain development and diseases, learning and memory, aging, and neuropsychiatric disorders. With multiple authors, the 27 chapters of this book contain the latest work in two volumes. The first presents the basic biology of adult neurogenesis in non-mammalian vertebrates and in the mammalian hippocampus and olfactory bulb, and the second discusses clinical implications and delves into adult neurogenesis and brain injury as well as neurodegenerative and neuropsychiatric pathologies. With details of the anatomy, physiology, and molecular biology of the two neurogenic brain regions, this book provides indispensable knowledge for many areas of neuroscience and for experimental and clinical applications of adult neurogenesis to brain therapy.

Neurobiology of the Parental Brain

Author : Robert Bridges
Publisher : Elsevier
ISBN 13 : 9780080559575
Total Pages : 584 pages
Book Rating : 4.5/5 (595 download)

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Book Synopsis Neurobiology of the Parental Brain by : Robert Bridges

Download or read book Neurobiology of the Parental Brain written by Robert Bridges and published by Elsevier. This book was released on 2010-07-28 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents cutting edge research on the basic neurobiology of parental behavior as it relates to behavioral disorders, including postpartum depression, anxiety, and inadequate parental bonding to infants. Internationally recognized basic and clinical researchers present new research findings in humans and animals that elucidate the roles of the brain, physiological state, genes and environment in maternal and paternal care. By bridging the gap between basic and clinical research, new understandings of how the biology of the brain and the reproductive state of the parent impact their mental health and the successful rearing of young emerge. * Presents the neural network of motherhood based on fundamental and functional MRI studies of parental care - from rodents to humans * Discusses the role of gene-environment interactions in parenting * Offers parenting strategies and priorities in raising young * Discusses maternal defense - the neurobiology of maternal protection * Examines the significance and underlying causes of postpartum depression * Discusses parenting and anxiety – neurobiological basis for reductions during the postpartum period * Also includes the neurobiology of fatherhood – a fresh evolutionary and biological perspective on paternal behavior * Presents information on maternal neuroplasticity - how reproductive history changes the maternal brain * Translates research – internationally renowned researchers' insights into common factors that regulate mammalian parenting

The Neuroscience of Psychotherapy: Healing the Social Brain (Second Edition)

Author : Louis Cozolino
Publisher : W. W. Norton & Company
ISBN 13 : 0393706575
Total Pages : 480 pages
Book Rating : 4.3/5 (937 download)

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Book Synopsis The Neuroscience of Psychotherapy: Healing the Social Brain (Second Edition) by : Louis Cozolino

Download or read book The Neuroscience of Psychotherapy: Healing the Social Brain (Second Edition) written by Louis Cozolino and published by W. W. Norton & Company. This book was released on 2010-06-21 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: How the brain's architecture is related to the problems, passions, and aspirations of human beings. In contrast to this view, recent theoretical advances in brain imaging have revealed that the brain is an organ continually built and re-built by one's experience. We are now beginning to learn that many forms of psychotherapy, developed in the absence of any scientific understanding of the brain, are supported by neuroscientific findings. In fact, it could be argued that to be an effective psychotherapist these days it is essential to have some basic understanding of neuroscience. Louis Cozolino's The Neuroscience of Psychotherapy, Second Edition is the perfect place to start. In a beautifully written and accessible synthesis, Cozolino illustrates how the brain's architecture is related to the problems, passions, and aspirations of human beings. As the book so elegantly argues, all forms of psychotherapy--from psychoanalysis to behavioral interventions--are successful to the extent to which they enhance change in relevant neural circuits. Beginning with an overview of the intersecting fields of neuroscience and psychotherapy, this book delves into the brain's inner workings, from basic neuronal building blocks to complex systems of memory, language, and the organization of experience. It continues by explaining the development and organization of the healthy brain and the unhealthy brain. Common problems such as anxiety, trauma, and codependency are discussed from a scientific and clinical perspective. Throughout the book, the science behind the brain's working is applied to day-to-day experience and clinical practice. Written for psychotherapists and others interested in the relationship between brain and behavior, this book encourages us to consider the brain when attempting to understand human development, mental illness, and psychological health. Fully and thoroughly updated with the many neuroscientific developments that have happened in the eight years since the publication of the first edition, this revision to the bestselling book belongs on the shelf of all practitioners.

Clinical Neuroscience

Author : Kelly Lambert
Publisher : Oxford University Press, USA
ISBN 13 : 9780199737055
Total Pages : 0 pages
Book Rating : 4.7/5 (37 download)

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Book Synopsis Clinical Neuroscience by : Kelly Lambert

Download or read book Clinical Neuroscience written by Kelly Lambert and published by Oxford University Press, USA. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neuroscience informs students of relevant neurobiological foundations of various mental illnesses. In this book, students will begin their journey with a tour of the brain's fundamental building blocks (neuroanatomy, neurochemistry, neurophysiology, neurodevelopment) before moving to mental health challenges and illnesses (Traumatic brain injury, Parkinson's Disease, Addiction, Schizophrenia, Obsessive-Compulsive Disorder, Depression). The final section of the book includes chapters addressing topics thought to be important for building resilience against the emergence of mental illness; these chapters cover the topics of adaptive coping strategies, hunger regulation, and the nexus between mental and immune functions. Throughout the text, the value of empirical evidence is emphasized so that meaningful progress can be made toward the identification of the most effective treatment strategies. By understanding multiple neurobiological perspectives such as neuroanatomical, behavioral, evolutionary, and neurochemical approaches currently existing in the field, students will be better prepared to conceptualize the relevant components of these mental health puzzles. Features such as opening chapter vignettes (Connections), case studies (A Case in Point) and feature boxes (Brain Matters) illuminate the course content for students as they learn about the value of translational research. Instructor's Manual/Test Bank (9780199737079) to help instructors prepare for their lectures and homework assignments, with learning objectives, class activities and demonstrations, exercises, additional readings, and more. The test bank includes more than 800 questions organized topically and graded according to difficulty, with source information provided to link questions back to their respective sections in the text. Companion Website to further assist the instructor, providing PowerPoint versions of the most informative images and tables in the text

The Clinical Neurobiology of the Hippocampus

Author : Thorsten Bartsch
Publisher : Oxford University Press
ISBN 13 : 0199592381
Total Pages : 329 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis The Clinical Neurobiology of the Hippocampus by : Thorsten Bartsch

Download or read book The Clinical Neurobiology of the Hippocampus written by Thorsten Bartsch and published by Oxford University Press. This book was released on 2012-07-26 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus plays a key role in various clinical conditions such as acute amnesic syndromes, Alzheimer's disease, temporal lobe epilepsy (TLE), sleep disorders, stroke medicine encephalitis, depression, and schizophrenia. This book provides a comprehensive account of the role the hippocampus plays in disease.

Clinical Neuroscience

Author : Kelly Lambert
Publisher : Macmillan
ISBN 13 : 9780716752271
Total Pages : 666 pages
Book Rating : 4.7/5 (522 download)

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Book Synopsis Clinical Neuroscience by : Kelly Lambert

Download or read book Clinical Neuroscience written by Kelly Lambert and published by Macmillan. This book was released on 2004-11-26 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrating neurobiological mechanisms of general health into the coverage of mental disorders, this text also looks at other aspects of neuroscience and the ways in which it impacts on the mental condition.

From Neuroscience to Neurology

Author : Stephen Waxman
Publisher : Elsevier
ISBN 13 : 0080506984
Total Pages : 552 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis From Neuroscience to Neurology by : Stephen Waxman

Download or read book From Neuroscience to Neurology written by Stephen Waxman and published by Elsevier. This book was released on 2004-11-05 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of neurology is being transformed, from a therapeutically nihilistic discipline with few effective treatments, to a therapeutic specialty which offers new, effective treatments for disorders of the brain and spinal cord. This remarkable transformation has bridged neuroscience, molecular medicine, and clinical investigation, and represents a major triumph for biomedical research. This book, which contains chapters by more than 29 internationally recognized authorities who have made major contributions to neurotherapeutics, tells the stories of how new treatments for disabling disorders of the nervous system, such as stroke, multiple sclerosis, Parkinson’s disease, and migraine, were developed, and explores evolving themes and technologies that offer hope for even more effective treatments and ultimately cures for currently untreatable disorders of the brain and spinal cord. The first part of this book reviews the development of new therapies in neurology, from their inception in terms of basic science to their introduction into the clinical world. It also explores evolving themes and new technologies. This book will be of interest to everyone – clinicians and basic scientists alike – interested in diseases of the brain and spinal cord, and in the quest for new treatments for these disorders. * Presents the evolution of the field of neurology into a therapeutic discipline * Discusses lessons learned from past successes and applications to ongoing work * Explores the future of this field

Neurobiology of Brain Disorders

Author : Michael J. Zigmond
Publisher : Elsevier
ISBN 13 : 0123982804
Total Pages : 824 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Neurobiology of Brain Disorders by : Michael J. Zigmond

Download or read book Neurobiology of Brain Disorders written by Michael J. Zigmond and published by Elsevier. This book was released on 2014-12-03 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Imaging of the Human Brain in Health and Disease

Author : Philip Seeman
Publisher : Elsevier
ISBN 13 : 012418684X
Total Pages : 534 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Imaging of the Human Brain in Health and Disease by : Philip Seeman

Download or read book Imaging of the Human Brain in Health and Disease written by Philip Seeman and published by Elsevier. This book was released on 2013-11-15 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. A focused introduction to imaging healthy and diseased brains Focuses on the primary neurotransmitter release Includes sigma, acetylcholine, opioid, and dopamine receptors Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease

Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences

Author : Bernardo Dell'Osso
Publisher : Springer
ISBN 13 : 9783030433550
Total Pages : 370 pages
Book Rating : 4.4/5 (335 download)

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Book Synopsis Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences by : Bernardo Dell'Osso

Download or read book Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences written by Bernardo Dell'Osso and published by Springer. This book was released on 2020-07-24 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state of the art regarding the use of non-invasive brain stimulation (TMS and tDCS) in the research and treatment of neuropsychiatric disorders. The contributions, all of which were prepared by internationally recognized experts in the field, are divided into two main sections (for TMS and tDCS, respectively) across diagnoses, following an introductory section on the mechanisms of action and neurophysiological background. Neuropsychological perspectives and approaches are provided as well. The book is ultimately intended to offer a unique, integrated approach to the use of non-invasive brain stimulation across the clinical neurosciences, providing a comprehensive and updated perspective that will benefit psychiatrists, neurologists, clinical psychologists and neurophysiologists alike.

Mapping the Brain and Its Functions

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309044979
Total Pages : 180 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Mapping the Brain and Its Functions by : Institute of Medicine

Download or read book Mapping the Brain and Its Functions written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances in brain research have been made, but investigators who face the resulting explosion of data need new methods to integrate the pieces of the "brain puzzle." Based on the expertise of more than 100 neuroscientists and computer specialists, this new volume examines how computer technology can meet that need. Featuring outstanding color photography, the book presents an overview of the complexity of brain research, which covers the spectrum from human behavior to genetic mechanisms. Advances in vision, substance abuse, pain, and schizophrenia are highlighted. The committee explores the potential benefits of computer graphics, database systems, and communications networks in neuroscience and reviews the available technology. Recommendations center on a proposed Brain Mapping Initiative, with an agenda for implementation and a look at issues such as privacy and accessibility.

The Role of Brain Dopamine

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642738974
Total Pages : 62 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Role of Brain Dopamine by :

Download or read book The Role of Brain Dopamine written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: As in other volumes in the series, this newest volume conveys up-to-date knowledge in a clear and straightforward manner. It begins with a survey of the neurobiological functions of the brain, with the emphasis on Parkinson's disease. This is followed by a presentation of the role of dopamine in the regulation of human anterior pituitary function. The final two chapters concentrate on the dopamine receptors: first, the binding sites are characterized and the biochemical and physiological consequences of dopamine-receptor stimulation are discussed and, finally, there is a report on the topology of a dopamine-receptor model that can account comprehensively for agonists and antagonists.