Synthetic Dna And Rna Programming

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Synthetic DNA and RNA Programming

Author : Patrick O’Donoghue
Publisher : MDPI
ISBN 13 : 3039217348
Total Pages : 188 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Synthetic DNA and RNA Programming by : Patrick O’Donoghue

Download or read book Synthetic DNA and RNA Programming written by Patrick O’Donoghue and published by MDPI. This book was released on 2019-11-19 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dear Colleagues, Synthetic biology is a broad and emerging discipline that capitalizes on recent advances in molecular biology, genetics, protein and RNA engineering and omics technologies. These technologies have transformed our ability to reveal the biology of the cell and the molecular basis of disease. This Special Issue on “Synthetic RNA and DNA Programming” features original research articles and reviews, highlighting novel aspects of basic molecular biology and the molecular mechanisms of disease that were uncovered by the application and development of novel synthetic biology-driven approaches.

Synthetic DNA and RNA Programming

Author : Patrick O'Donoghue
Publisher :
ISBN 13 : 9783039217359
Total Pages : 188 pages
Book Rating : 4.2/5 (173 download)

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Book Synopsis Synthetic DNA and RNA Programming by : Patrick O'Donoghue

Download or read book Synthetic DNA and RNA Programming written by Patrick O'Donoghue and published by . This book was released on 2019 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dear Colleagues, Synthetic biology is a broad and emerging discipline that capitalizes on recent advances in molecular biology, genetics, protein and RNA engineering and omics technologies. These technologies have transformed our ability to reveal the biology of the cell and the molecular basis of disease.

Biodefense in the Age of Synthetic Biology

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309465184
Total Pages : 189 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Biodefense in the Age of Synthetic Biology by : National Academies of Sciences, Engineering, and Medicine

Download or read book Biodefense in the Age of Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-05 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

The Science and Applications of Synthetic and Systems Biology

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309219396
Total Pages : 570 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine

Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Cell-Free Synthetic Biology

Author : Jian Li
Publisher : Frontiers Media SA
ISBN 13 : 2889740803
Total Pages : 205 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Cell-Free Synthetic Biology by : Jian Li

Download or read book Cell-Free Synthetic Biology written by Jian Li and published by Frontiers Media SA. This book was released on 2022-01-13 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Small Molecule DNA and RNA Binders

Author : Martine Demeunynck
Publisher : John Wiley & Sons
ISBN 13 : 3527605665
Total Pages : 754 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Small Molecule DNA and RNA Binders by : Martine Demeunynck

Download or read book Small Molecule DNA and RNA Binders written by Martine Demeunynck and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of molecules that selectively bind to nucleic acids has provided many details about DNA and RNA recognition. The range of such substances, such as metal complexes, peptides, oligonucleotides and a wide array of synthetic organic compounds, is as manifold as the functions of nucleic acids. Nucleic acid recognition sequences are often found in the major or minor groove of a double strand, while other typical interactions include intercalation between base pairs or the formation of triple or quadruple helices. One example of a binding mode that has recently been proposed is end stacking on such complex structures as the telomere tetraplex. In this comprehensive book, internationally recognized experts describe in detail the important aspects of nucleic acid binding, and in so doing present impressive approaches to drug design. Since typical substances may be created naturally or synthetically, emphasis is placed on natural products, chemical synthesis, the use of combinatorial libraries, and structural characterization. The whole is rounded off by contributions on molecular modeling, as well as investigations into the way in which any given drug interacts with its nucleic acid recognition site.

Synthesis and Applications of DNA and RNA

Author : Saran A. Narang
Publisher :
ISBN 13 : 9780125140300
Total Pages : 264 pages
Book Rating : 4.1/5 (43 download)

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Book Synopsis Synthesis and Applications of DNA and RNA by : Saran A. Narang

Download or read book Synthesis and Applications of DNA and RNA written by Saran A. Narang and published by . This book was released on 1987 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis And Applications Of DNA And RNA ...

Synthetic Biology â A Primer

Author : Paul S Freemont
Publisher : World Scientific Publishing Company
ISBN 13 : 1908977019
Total Pages : 196 pages
Book Rating : 4.9/5 (89 download)

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Book Synopsis Synthetic Biology â A Primer by : Paul S Freemont

Download or read book Synthetic Biology â A Primer written by Paul S Freemont and published by World Scientific Publishing Company. This book was released on 2012-06-04 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Biology — A Primer gives a broad overview of the emerging field of synthetic biology and the foundational concepts on which it is built. It will be of interest to final year undergraduates, postgraduates and established researchers who are interested in learning about this exciting new field. The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely ‘bottom-up’ and ‘top-down’ engineering approaches. ‘Top-down’ engineering utilises a conceptual framework of engineering and systematic design to build new biological systems by integrating robustly characterised biological parts into an existing system through the use of extensive mathematical modelling. The ‘bottom-up’ approach involves the design and building of synthetic protocells using basic chemical and biochemical building blocks from scratch. Exemplars of cutting-edge applications designed using synthetic biology principles are presented, including the production of novel biofuels from renewable feedstocks, microbial synthesis of pharmaceuticals and fine chemicals, and the design and implementation of biosensors to detect infections and environmental waste. The book also uses the Internationally Genetically Engineered Machine (iGEM) competition to illustrate the power of synthetic biology as an innovative research and training science. Finally, the primer includes a chapter on the ethical, legal and societal issues surrounding synthetic biology, illustrating the integration of social sciences in synthetic biology research. Sample Chapter(s) Chapter 1: Introduction to Biology (13,411 KB) Chapter 2: Basic Concepts in Engineering (4,954 KB) Request Inspection Copy

Synthetic Biology

Author : Christina Smolke
Publisher : John Wiley & Sons
ISBN 13 : 3527688099
Total Pages : 1600 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Synthetic Biology by : Christina Smolke

Download or read book Synthetic Biology written by Christina Smolke and published by John Wiley & Sons. This book was released on 2018-02-28 with total page 1600 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of the interdisciplinary field of synthetic biology, from genome design to spatial engineering. Written by an international panel of experts, Synthetic Biology draws from various areas of research in biology and engineering and explores the current applications to provide an authoritative overview of this burgeoning field. The text reviews the synthesis of DNA and genome engineering and offers a discussion of the parts and devices that control protein expression and activity. The authors include information on the devices that support spatial engineering, RNA switches and explore the early applications of synthetic biology in protein synthesis, generation of pathway libraries, and immunotherapy. Filled with the most recent research, compelling discussions, and unique perspectives, Synthetic Biology offers an important resource for understanding how this new branch of science can improve on applications for industry or biological research.

Advances in Synthetic Biology

Author : Vijai Singh
Publisher : Springer Nature
ISBN 13 : 9811500819
Total Pages : 349 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Advances in Synthetic Biology by : Vijai Singh

Download or read book Advances in Synthetic Biology written by Vijai Singh and published by Springer Nature. This book was released on 2020-04-13 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the design of emerging conceptual tools, technologies and systems including novel synthetic parts, devices, circuits, oscillators, biological gates, and small regulatory RNAs (riboregulators and riboswitches), which serve as versatile control elements for regulating gene expression. Synthetic biology, a rapidly growing field that involves the application of engineering principles in biology, is now being used to develop novel systems for a wide range of applications including diagnostics, cell reprogramming, therapeutics, enzymes, vaccines, biomaterials, biofuels, fine chemicals and many more. The book subsequently summarizes recent developments in technologies for assembling synthetic genomes, minimal genomes, synthetic biology toolboxes, CRISPR-Cas systems, cell-free protein synthesis systems and microfluidics. Accordingly, it offers a valuable resource not only for beginners in synthetic biology, but also for researchers, students, scientists, clinicians, stakeholders and policymakers interested in the potential held by synthetic biology.

Genome Refactoring

Author : Natalie Kuldell
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1598299484
Total Pages : 78 pages
Book Rating : 4.5/5 (982 download)

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Book Synopsis Genome Refactoring by : Natalie Kuldell

Download or read book Genome Refactoring written by Natalie Kuldell and published by Morgan & Claypool Publishers. This book was released on 2009-05-08 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: The science of biology celebrates the discovery and understanding of biological systems that already exist in nature. In parallel, the engineering of biology must learn how to make use of our understanding of the natural world to design and build new useful biological systems. "Synthetic biology" represents one example of recent work to engineer biological systems. This emerging field aims to replace the ad hoc process of assembling biological systems by primarily developing tools to assemble reliable-but-complex living organisms from standard components that can later be reused in new combination. The focus of this book is "genome refactoring," one of several approaches to manage the complexity of a biological system in which the goal is to redesign the genetic elements that encode a living form--preserving the function of that form but encoding it with a genome far easier to study and extend. This book presents genome refactoring in two ways: as an important aspect of the emerging field of synthetic biology and as a powerful teaching tool to train would be professionals in the subject. Chapters focus on the overarching goals of synthetic biology and their alignment with the motivations and achievements in genome engineering; the engineering frameworks of refactoring, including genome synthesis, standardization of biological parts, and abstraction; a detailed description of the bacteriophages that have been refactored up to this point; and the methods of refactoring and contexts for that work drawn from the bacteriophage M13. Overall, these examples offer readers the potential for synthetic biology and the areas in need of further research. If successful, synthetic biology and genome refactoring could address any number of persistent societal needs, including sustainable energy, affordable and effective medicine, and green manufacturing practices. Table of Contents: Tools for Genome Engineering and Synthetic Biology / Bacteriophage as Templates for Refactoring / Methods/Teaching Protocols for M13 Reengineering / Writing and Speaking as Biological Engineers / Summary and Future Directions / Appendix A / Appendix B / Appendix C

Biological Sequence Analysis

Author : Richard Durbin
Publisher :
ISBN 13 : 9780511337086
Total Pages : 0 pages
Book Rating : 4.3/5 (37 download)

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Book Synopsis Biological Sequence Analysis by : Richard Durbin

Download or read book Biological Sequence Analysis written by Richard Durbin and published by . This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents up-to-date computer methods for analysing DNA, RNA and protein sequences.

Synthetic DNA

Author : Randall A. Hughes
Publisher :
ISBN 13 : 9781493963430
Total Pages : 248 pages
Book Rating : 4.9/5 (634 download)

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Book Synopsis Synthetic DNA by : Randall A. Hughes

Download or read book Synthetic DNA written by Randall A. Hughes and published by . This book was released on 2017 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents state-of-the art methods for the synthesis, design, assembly, post synthesis processing, and application of synthetic DNA to modern biotechnology. Chapters are divided into three general sections focusing on protocols for the computational design of synthetic DNA sequences, the synthesis, assembly and cloning of synthetic DNA, and post-synthesis error reduction strategies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Synthetic DNA: Methods and Protocols aims to help researchers further their research on manipulate DNA sequences.

Synthetic Gene Networks

Author : Wilfried Weber
Publisher : Humana Press
ISBN 13 : 9781617794117
Total Pages : 393 pages
Book Rating : 4.7/5 (941 download)

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Book Synopsis Synthetic Gene Networks by : Wilfried Weber

Download or read book Synthetic Gene Networks written by Wilfried Weber and published by Humana Press. This book was released on 2011-11-17 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid expansion of synthetic biology is due to the design and construction of synthetic gene networks that have opened many new avenues in fundamental and applied research. Synthetic Gene Networks: Methods and Protocols provides the necessary information to design and construct synthetic gene networks in different host backgrounds. Divided into four convenient sections, this volume focuses on design concepts to devise synthetic gene networks and how mathematical models can be applied to the predictable engineering of desired network features. The volume continues by highlighting the construction and validation of biologic tools, describing strategies to optimize and streamline the host cell for optimized network performance, and covering how optimally designed gene networks can be implemented in a large variety of host cells ranging from bacteria over yeast and insect cells to plant and mammalian cell culture. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Synthetic Gene Networks: Methods and Protocols serves as an invaluable resource for established biologists, engineers, and computer scientists or novices just entering into the rapidly growing field of synthetic biology

Chemical Synthetic Biology

Author : Pier Luigi Luisi
Publisher : John Wiley & Sons
ISBN 13 : 1119990300
Total Pages : 269 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Chemical Synthetic Biology by : Pier Luigi Luisi

Download or read book Chemical Synthetic Biology written by Pier Luigi Luisi and published by John Wiley & Sons. This book was released on 2011-02-10 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry plays a very important role in the emerging field of synthetic biology. In particular, chemical synthetic biology is concerned with the synthesis of chemical structures, such as proteins, that do not exist in nature. With contributions from leading international experts, Chemical Synthetic Biology shows how chemistry underpins synthetic biology. The book is an essential guide to this fascinating new field, and will find a place on the bookshelves of researchers and students working in synthetic chemistry, synthetic and molecular biology, bioengineering, systems biology, computational genomics, and bioinformatics.

Computation in BioInformatics

Author : S. Balamurugan
Publisher : John Wiley & Sons
ISBN 13 : 1119654718
Total Pages : 354 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Computation in BioInformatics by : S. Balamurugan

Download or read book Computation in BioInformatics written by S. Balamurugan and published by John Wiley & Sons. This book was released on 2021-10-19 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: COMPUTATION IN BIOINFORMATICS Bioinformatics is a platform between the biology and information technology and this book provides readers with an understanding of the use of bioinformatics tools in new drug design. The discovery of new solutions to pandemics is facilitated through the use of promising bioinformatics techniques and integrated approaches. This book covers a broad spectrum of the bioinformatics field, starting with the basic principles, concepts, and application areas. Also covered is the role of bioinformatics in drug design and discovery, including aspects of molecular modeling. Some of the chapters provide detailed information on bioinformatics related topics, such as silicon design, protein modeling, DNA microarray analysis, DNA-RNA barcoding, and gene sequencing, all of which are currently needed in the industry. Also included are specialized topics, such as bioinformatics in cancer detection, genomics, and proteomics. Moreover, a few chapters explain highly advanced topics, like machine learning and covalent approaches to drug design and discovery, all of which are significant in pharma and biotech research and development. Audience Researchers and engineers in computation biology, information technology, bioinformatics, drug design, biotechnology, pharmaceutical sciences.

DNA Computing and Molecular Programming

Author : Robert Brijder
Publisher : Springer
ISBN 13 : 3319667998
Total Pages : 278 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis DNA Computing and Molecular Programming by : Robert Brijder

Download or read book DNA Computing and Molecular Programming written by Robert Brijder and published by Springer. This book was released on 2017-08-22 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 23th International Conference on DNA Computing and Molecular Programming, DNA 23, held Austin, TX, USA, in September 2017. The 16 full papers presented were carefully selected from 23 submissions. Research in DNA computing aims to draw together mathematics, computerscience, physics, chemistry, biology, and nanotechnology to address the analysis, design, and synthesis of information-based molecular systems. The papers address all areas related to biomolecular computing such as: algorithms and models for computation with biomolecular systems; computational processes in vitro and in vivo; molecular motors and molecular robotics; studies of fault-tolerance and error correction; software tools for analysis, simulation, and design; synthetic biology and in vitro evolution; applications in engineering, physics, chemistry, biology, and medicine.