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Synthesis And Structural Investigations Of Alpha Peptides Alpha Peptides Containing Beta Aminocyclopropane Beta Aminocyclopropane Dicarboxylic Acids
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Book Synopsis Synthesis and Structural Investigations of [alpha]-peptides [alpha-peptides] Containing [beta]-aminocyclopropane [beta-aminocyclopropane] Dicarboxylic Acids by : Chiara Zorn
Download or read book Synthesis and Structural Investigations of [alpha]-peptides [alpha-peptides] Containing [beta]-aminocyclopropane [beta-aminocyclopropane] Dicarboxylic Acids written by Chiara Zorn and published by . This book was released on 2001 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis and Structural Investigations of Alpha-peptides Containing Beta-aminocyclopropane Dicarboxylic Acids by : Chiara Zorn
Download or read book Synthesis and Structural Investigations of Alpha-peptides Containing Beta-aminocyclopropane Dicarboxylic Acids written by Chiara Zorn and published by . This book was released on 2001 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis, Conformational Investigations and Applications of [alpha]-peptides [alpha-peptides] Containing Cis-[beta]-aminocyclopropane [cis-beta-aminocyclopropane] Dicarboxylic Acids by : Silvia De Pol
Download or read book Synthesis, Conformational Investigations and Applications of [alpha]-peptides [alpha-peptides] Containing Cis-[beta]-aminocyclopropane [cis-beta-aminocyclopropane] Dicarboxylic Acids written by Silvia De Pol and published by . This book was released on 2006 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis, Conformational Investigations and Applications of Alpha-peptides Containing Cis-beta-aminocyclopropane Dicarboxylic Acids by : Silvia De Pol
Download or read book Synthesis, Conformational Investigations and Applications of Alpha-peptides Containing Cis-beta-aminocyclopropane Dicarboxylic Acids written by Silvia De Pol and published by . This book was released on 2006 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis, Conformational Investigations and Applications of Α-peptides [alpha-peptides] Containing Cis-β-aminocyclopropane [cis-beta-aminocyclopropane] Dicarboxylic Acids by : Silvia De Pol
Download or read book Synthesis, Conformational Investigations and Applications of Α-peptides [alpha-peptides] Containing Cis-β-aminocyclopropane [cis-beta-aminocyclopropane] Dicarboxylic Acids written by Silvia De Pol and published by . This book was released on 2006 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Design, Synthesis, and Structural Investigation of Nucleobase Functionalized Β-peptides [beta-peptides] by : Pradip Chakraborty
Download or read book Design, Synthesis, and Structural Investigation of Nucleobase Functionalized Β-peptides [beta-peptides] written by Pradip Chakraborty and published by Cuvillier Verlag. This book was released on 2005 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Branched Α-[alpha-] and Β-amino[beta-amino] Acids Using C-nucleophile Additions to Imines and Nitrones by : Alevtina Baskakova
Download or read book Synthesis of Branched Α-[alpha-] and Β-amino[beta-amino] Acids Using C-nucleophile Additions to Imines and Nitrones written by Alevtina Baskakova and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial peptides, containing alpha- and/or beta-amino acids with bulky substituents, can potentially possess some unusual properties, for example, decreased conformational ability or formation of stable secondary structures. Therefore, the preparation of such unnatural amino acids is of high interest. In this thesis, a route to enantiomerically pure 1-adamantylglycine was developed. The crucial step was the highly stereoselective addition of adamantylmagnesium bromide to the C=N bond of 2,3-O-cyclohexylidene-D-glyceraldehyde N-benzylnitrone effected in the presence of Lewis acid. Finally, 1-adamantylglycine was synthesized in 28 % yield over 6 steps. The routes to 9-aminofluorenylacetic and beta-aminobeta, beta-diphenylpropionic acids were proposed and they consist in the addition of allyl Grignard reagents to imines with various protecting groups, followed by oxidative transformation of the allyl group. Also some procedures for the preparation of 3,3-disubstituted 4-azetidinones, direct precursors of the corresponding beta-branched beta-amino acids, have been investigated.
Book Synopsis Synthesis, Structural Characterization, Conformational Analysis, and Plasma Stability Studies of [alpha]/[delta]-hybrid Peptides Derived from 2,3-dehydroneuraminic Acid and Glutamic Acids by : Jonel Penaranda Saludes
Download or read book Synthesis, Structural Characterization, Conformational Analysis, and Plasma Stability Studies of [alpha]/[delta]-hybrid Peptides Derived from 2,3-dehydroneuraminic Acid and Glutamic Acids written by Jonel Penaranda Saludes and published by . This book was released on 2009 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Functionalized, [beta]-silicon-containing Nonproteinogenic [alpha]-amino Acids for Potential Use in Peptide-based Pharmacological Therapy by :
Download or read book Synthesis of Functionalized, [beta]-silicon-containing Nonproteinogenic [alpha]-amino Acids for Potential Use in Peptide-based Pharmacological Therapy written by and published by . This book was released on 2014 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Mixed [alpha]/[beta]-peptides and NMR-solution Structure of F/OH-substituted and Other [beta]-peptides by : Raveendra I. Mathad
Download or read book Synthesis of Mixed [alpha]/[beta]-peptides and NMR-solution Structure of F/OH-substituted and Other [beta]-peptides written by Raveendra I. Mathad and published by . This book was released on 2007 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of New [beta]-amino Acids and Novel [beta]-peptides, and Structural Investigations by : Gérald Patrick Joseph Jean Louis Lelais
Download or read book Synthesis of New [beta]-amino Acids and Novel [beta]-peptides, and Structural Investigations written by Gérald Patrick Joseph Jean Louis Lelais and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of New [beta]-amino Acids and Novel [beta]-peptides, and Structural Investigations by : Gérald Patrick Joseph Jean Louis Lelais
Download or read book Synthesis of New [beta]-amino Acids and Novel [beta]-peptides, and Structural Investigations written by Gérald Patrick Joseph Jean Louis Lelais and published by . This book was released on 2004 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of [alpha]-helix-like [alpha]/[beta]/[upsilon] Foldamers by :
Download or read book Development of [alpha]-helix-like [alpha]/[beta]/[upsilon] Foldamers written by and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Helical peptidomimetics that contain non-natural amino acid residues, such as beta- and gamma-amino acid residues, are less prone to proteolytic degradation than are conventional peptides (composed exclusively of alpha-amino acid residues). However, the additional backbone atoms in beta- and gamma-residues relative to alpha-residues may increase backbone flexibility, and thereby increase the entropic penalty upon binding to a protein partner, resulting in decreased affinity for the targets. Ring-constrained beta- and gamma-amino acids have been developed to address this problem by pre-organizing the residues for helical conformations. This thesis details development of alpha-helix-like alpha/beta/gamma foldamers containing cyclic and/or acyclic beta- and gamma-amino acid residues. Chapters 2 and 3 discuss biophysical investigations of helical alpha/beta/gamma-peptides. Studies of the ring-constrained beta- and gamma-residues' effects on the helicity of alpha/beta/gamma-peptides suggest that beta(3)- and gamma(4)- amino acid residues differ in their intrinsic tendencies to adopt helical secondary structure, with gamma(4)-residues displaying a higher propensity than beta(3)- residues. Different acyclic gamma-residues, and different patterns of alpha, beta and gamma residues in the backbone have been explored. The results show that as long as cyclically constrained beta-amino acids are incorporated into alpha/beta/gamma-peptides, the alpha/beta/gamma-peptide helical propensity is not very sensitive to the nature of the acyclic gamma-amino acids used (although gamma(4)-amino acids are the best helix-adopting acyclic residues) or the pattern of residues within the backbone. Chapter 4 discusses efforts to establish an alpha + alpha/beta/gamma coiled-coil system for use in thermodynamic analysis of alpha + alpha/beta/gamma coiled-coil folding propensities. Chapter 5 discusses efforts toward developing functional alpha/beta/gamma-peptides to modulate apoptosis-regulating protein-protein interactions.
Book Synopsis Design, Synthesis, and Structural Investigation of Nucleobase Functionalized [beta]-peptides by : Pradip Chakraborty
Download or read book Design, Synthesis, and Structural Investigation of Nucleobase Functionalized [beta]-peptides written by Pradip Chakraborty and published by . This book was released on 2005 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1988 with total page 1416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2068 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Book Synopsis Comprehensive Dissertation Index by :
Download or read book Comprehensive Dissertation Index written by and published by . This book was released on 1989 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: