Surface Activity in Drug Action

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Author :
Publisher : Elsevier
ISBN 13 : 9780080456119
Total Pages : 340 pages
Book Rating : 4.4/5 (561 download)

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Book Synopsis Surface Activity in Drug Action by :

Download or read book Surface Activity in Drug Action written by and published by Elsevier. This book was released on 2005-03-01 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface activity is present in living systems; for example in body fluid or cell soup and molecules of surface-active nature are crucial to living matter and its organization. Surface Activity in Drug Action proposes "a liquid membrane hypothesis of drug action" for surface-active drugs. Chapters 1-7 contains an account of the hypothesis and chapter 8 contains a general account of the application of surface activity in therapeutics. The methodology and presentation of the information makes Surface Activity in Drug Action valuable reading for students and researchers interested in surface activity. * Is clearly written * Includes contributions from prominent names in the field, such as Bhise and Subrahmanyam * Contains a general account of the application of surface activity in therapeutics

Drug-like Properties: Concepts, Structure Design and Methods

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Author :
Publisher : Elsevier
ISBN 13 : 0080557619
Total Pages : 549 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Drug-like Properties: Concepts, Structure Design and Methods by : Li Di

Download or read book Drug-like Properties: Concepts, Structure Design and Methods written by Li Di and published by Elsevier. This book was released on 2010-07-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. Serves as an essential working handbook aimed at scientists and students in medicinal chemistry Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies Discusses improvements in pharmacokinetics from a practical chemist's standpoint

Physico-chemical Aspects of Drug Action

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Publisher :
ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Physico-chemical Aspects of Drug Action by : Everhardus Jacobus Ariëns

Download or read book Physico-chemical Aspects of Drug Action written by Everhardus Jacobus Ariëns and published by . This book was released on 1968 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Goodman and Gilman's Manual of Pharmacology and Therapeutics

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Publisher : McGraw Hill Professional
ISBN 13 : 0071443436
Total Pages : 1232 pages
Book Rating : 4.0/5 (714 download)

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Book Synopsis Goodman and Gilman's Manual of Pharmacology and Therapeutics by : Louis Sanford Goodman

Download or read book Goodman and Gilman's Manual of Pharmacology and Therapeutics written by Louis Sanford Goodman and published by McGraw Hill Professional. This book was released on 2008 with total page 1232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Put the authority of Goodman & Gilman's in the palm of your hand! 5 STAR DOODY'S REVIEW! "...the most authoritative and trusted source of pharmacological information, has now spawned a portable pocket drug guide....This manual extracts the essential core drug information from the eleventh edition of the parent book, referring the reader to the online version of the parent book for historical aspects, many chemical and clinical details, and additional figures and references. This makes G & G a very useful book. This will be of use to individuals in training or practice in the fields of pharmacy, medicine, nursing, or allied health disciplines where knowledge of drug actions are important....Each chapter provides the core essential information provided in the parent book in a very readable format. Readers can use this easy to handle and read manual for essential information along with the online version of the parent book as a reference for more in-depth specific information on drugs."--Doody's Review Service The Goodman & Gilman Manual of Pharmacology and Therapeutics offers the renowned content of Goodman & Gilman's Pharmacological Basis of Therapeutics, Eleventh Edition, condensed into an ultra-handy, streamlined reference. More than just a pocket drug guide, this indispensable resource offers: A carry-along source of essential fundamental information, with all the authority of Goodman & Gilman's Pharmacological Basis of Therapeutics, Eleventh Edition The benefits of the world's leading pharmacology text in a convenient, portable format Comprehensive, yet streamlined and clinically relevant coverage of the pharmacological basis of therapeutics High-yield overview of pharmacokinetics, pharmacodynamics, and the foundations of pharmacology Expert insights into the properties, mechanisms, and uses of all the major drug classes Considerations of vital patient-specific issues

Anesthetic Pharmacology

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Publisher : Cambridge University Press
ISBN 13 : 1139497022
Total Pages : pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Anesthetic Pharmacology by : Alex S. Evers

Download or read book Anesthetic Pharmacology written by Alex S. Evers and published by Cambridge University Press. This book was released on 2011-03-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Handbook of Pharmaceutical Salts Properties, Selection, and Use

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9783906390581
Total Pages : 392 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis Handbook of Pharmaceutical Salts Properties, Selection, and Use by : P. Heinrich Stahl

Download or read book Handbook of Pharmaceutical Salts Properties, Selection, and Use written by P. Heinrich Stahl and published by John Wiley & Sons. This book was released on 2008-08-04 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive up-to-date guide and information source is an instructive companion for all scientists involved in research and development of drugs and, in particular, of pharmaceutical dosage forms. The editors have taken care to address every conceivable aspect of the preparation of pharmaceutical salts and present the necessary theoretical foundations as well as a wealth of detailed practical experience in the choice of pharmaceutically active salts. Altogether, the contributions reflect the multidisciplinary nature of the science involved in selection of suitable salt forms for new drug products.

Oral Drug Absorption

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Publisher : CRC Press
ISBN 13 : 1420077341
Total Pages : 432 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Oral Drug Absorption by : Jennifer B. Dressman

Download or read book Oral Drug Absorption written by Jennifer B. Dressman and published by CRC Press. This book was released on 2016-04-19 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral Drug Absorption, Second Edition thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The contributors discuss methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR an

Introduction to Basics of Pharmacology and Toxicology

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Publisher : Springer Nature
ISBN 13 : 9813297794
Total Pages : 410 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Introduction to Basics of Pharmacology and Toxicology by : Gerard Marshall Raj

Download or read book Introduction to Basics of Pharmacology and Toxicology written by Gerard Marshall Raj and published by Springer Nature. This book was released on 2019-11-16 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.

Medicinal Chemistry

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Publisher : New Age International
ISBN 13 : 9788122415650
Total Pages : 832 pages
Book Rating : 4.4/5 (156 download)

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Book Synopsis Medicinal Chemistry by : Ashutosh Kar

Download or read book Medicinal Chemistry written by Ashutosh Kar and published by New Age International. This book was released on 2005 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Qualified Success And General Appeal Of Medicinal Chemistry Is Not Only Confined To The Indian Subcontinent, But It Has Also Won An Overwhelming Popularity In Other Parts Of The World. Specific Care Has Been Taken To Maintain And Sustain The Fundamental Philosophy Of The Textbook Embracing Rigidly The Original Pattern And Style Of Presentation With A Particular Expatiated Treatment Of Synthesis Of Potential Medicinal Compounds For The Ultimate Benefits Of The Teachers And The Taught Alike.The Present Thoroughly Revised And Skilfully Expanded Fourth Edition Essentially Contains Three New And Important Chapters, Namely : Molecular Modeling And Drug Design (Chapter 3), Adrenocortical Steroids (Chapter 24), And Antimycobacterial Agents (Chapter 26) So As To Make The Textbook More Useful To Its Readers.With The Advent Of Thirty Chapters The Present Updated Form Of Medicinal Chemistry Will Prove To Be An Asset For M. Pharm./B. Pharm. Degree Students, M. Sc. Pharmaceutical Chemistry, M.Sc. Applied Chemistry And M. Sc. Industrial Chemistry Throughout The Indian Universities.Medicinal Chemistry Appears As A Newly Designed And Artistically Presented In A Two-Colour Scheme So As To Facilitate A Distinctly More Effective Use Of The Book.This Highly Readable, Lucid, Handy, And Exceptionally Knowledgeable Textbook Will Definitely Win A Better, Bigger, And Confident Place For Itself Amongst Its Valued Readers.

Membrane Transporters as Drug Targets

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0306460947
Total Pages : 547 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Membrane Transporters as Drug Targets by : Gordon L. Amidon

Download or read book Membrane Transporters as Drug Targets written by Gordon L. Amidon and published by Springer Science & Business Media. This book was released on 1999-11-30 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because progress in the field of transporters has been extraordinary, this volume will focus on recent advances in our understanding of the structure, function, physiology, and molecular biology of membrane transporters. There will be an emphasis on transporters as molecular targets for drug delivery and disposition in the body.

Drug Metabolism in Diseases

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Publisher : Academic Press
ISBN 13 : 9780128029497
Total Pages : 0 pages
Book Rating : 4.0/5 (294 download)

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Book Synopsis Drug Metabolism in Diseases by : Wen Xie

Download or read book Drug Metabolism in Diseases written by Wen Xie and published by Academic Press. This book was released on 2016-09-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states. Each chapter clearly presents the effects of changes in drug metabolism and drug transporters on pharmacokinetics and disposition. This is a unique and useful approach for all those involved in drug discovery and development, and for clinicians and researchers in drug metabolism, pharmacology, and clinical pharmacology.

Toxicity Bibliography

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Publisher :
ISBN 13 :
Total Pages : 856 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Bibliography by :

Download or read book Toxicity Bibliography written by and published by . This book was released on 1976 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Transporters

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Publisher : Springer Science & Business Media
ISBN 13 : 3642145418
Total Pages : 454 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Drug Transporters by : Martin F. Fromm

Download or read book Drug Transporters written by Martin F. Fromm and published by Springer Science & Business Media. This book was released on 2010-11-19 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.

Cerebrovascular Bibliography

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Publisher :
ISBN 13 :
Total Pages : 1446 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Cerebrovascular Bibliography by :

Download or read book Cerebrovascular Bibliography written by and published by . This book was released on 1968 with total page 1446 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Safe and Effective Medicines for Children

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Publisher : National Academies Press
ISBN 13 : 0309225493
Total Pages : 432 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Safe and Effective Medicines for Children by : Institute of Medicine

Download or read book Safe and Effective Medicines for Children written by Institute of Medicine and published by National Academies Press. This book was released on 2012-10-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the IOM to review aspects of pediatric studies and changes in product labeling that resulted from BPCA and PREA and their predecessor policies, as well as assess the incentives for pediatric studies of biologics and the extent to which biologics have been studied in children. The IOM committee concludes that these policies have helped provide clinicians who care for children with better information about the efficacy, safety, and appropriate prescribing of drugs. The IOM suggests that more can be done to increase knowledge about drugs used by children and thereby improve the clinical care, health, and well-being of the nation's children.

Psychopharmacology Abstracts

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Author :
Publisher :
ISBN 13 :
Total Pages : 832 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Psychopharmacology Abstracts by :

Download or read book Psychopharmacology Abstracts written by and published by . This book was released on 1970 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmaceutical Calculations

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Publisher :
ISBN 13 : 9780812110074
Total Pages : 428 pages
Book Rating : 4.1/5 (1 download)

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Book Synopsis Pharmaceutical Calculations by : Mitchell J. Stoklosa

Download or read book Pharmaceutical Calculations written by Mitchell J. Stoklosa and published by . This book was released on 1986 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: