The Comprehensive Guide To Clinical Research

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Author :
Publisher : Independently Published
ISBN 13 : 9781090349521
Total Pages : 218 pages
Book Rating : 4.3/5 (495 download)

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Book Synopsis The Comprehensive Guide To Clinical Research by : Chris Sauber

Download or read book The Comprehensive Guide To Clinical Research written by Chris Sauber and published by Independently Published. This book was released on 2019-04-21 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Condensing the most important topics in all of clinical research in an easy to understand presentation. The 20 percent of what you need to know in order to be 80 percent proficient!The authors who have operated various levels of businesses in the clinical research industry since 2005 believe that more practical information pertaining to clinical research needs to be accessible to individuals who are new to the industry or are curious about entering the rewarding world of clinical trials.This book reads in an easy to understand style and is based on proven methods the authors have developed to train their own employees and students of their various clinical research academies throughout the years. Picking this up and absorbing the information will allow anyone to gain much better insight into the complicated dynamics of clinical research. This practical roadmap is all you will need to get started on your clinical trial journey!In this book you will learn about:Regulations and the history as well as evolution of GCP.Clinical Research Site OperationsMonitoring Dynamics and Typical Monitoring VistsCRO ActivitiesSponsor Level DynamicsIndustry VendorsCommon Career Opportunities and Employment Roadmaps

Principles and Practice of Clinical Research

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Author :
Publisher : Elsevier
ISBN 13 : 0080489567
Total Pages : 447 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Principles and Practice of Clinical Research by : John I. Gallin

Download or read book Principles and Practice of Clinical Research written by John I. Gallin and published by Elsevier. This book was released on 2011-04-28 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.*Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government

Evaluating AIDS Prevention Programs

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Author :
Publisher : National Academies Press
ISBN 13 : 030904281X
Total Pages : 391 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Evaluating AIDS Prevention Programs by : National Research Council

Download or read book Evaluating AIDS Prevention Programs written by National Research Council and published by National Academies Press. This book was released on 1991-02-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: With insightful discussion of program evaluation and the efforts of the Centers for Disease Control, this book presents a set of clear-cut recommendations to help ensure that the substantial resources devoted to the fight against AIDS will be used most effectively. This expanded edition of Evaluating AIDS Prevention Programs covers evaluation strategies and outcome measurements, including a realistic review of the factors that make evaluation of AIDS programs particularly difficult. Randomized field experiments are examined, focusing on the use of alternative treatments rather than placebo controls. The book also reviews nonexperimental techniques, including a critical examination of evaluation methods that are observational rather than experimentalâ€"a necessity when randomized experiments are infeasible.

Small Clinical Trials

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Publisher : National Academies Press
ISBN 13 : 0309171148
Total Pages : 221 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Small Clinical Trials by : Institute of Medicine

Download or read book Small Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

Design and Development Research

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Publisher : Routledge
ISBN 13 : 1136791280
Total Pages : 208 pages
Book Rating : 4.1/5 (367 download)

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Book Synopsis Design and Development Research by : Rita C. Richey

Download or read book Design and Development Research written by Rita C. Richey and published by Routledge. This book was released on 2014-07-16 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: AECT Design & Development Outstanding Book Award for 2008! Design and Development Research thoroughly discusses methods and strategies appropriate for conducting design and development research. Rich with examples and explanations, the book describes actual strategies that researchers have used to conduct two major types of design and development research: 1) product and tool research and 2) model research. Common challenges confronted by researchers in the field when planning and conducting a study are explored and procedural explanations are supported by a wide variety of examples taken from current literature. Samples of actual research tools are also presented. Important features in this volume include: concise checklists at the end of each chapter to give a clear summary of the steps involved in the various phases of a project; an examination of the critical types of information and data often gathered in studies, and unique procedures for collecting these data; examples of data collection instruments, as well as the use of technology in data collection; and a discussion of the process of extracting meaning from data and interpreting product and tool and model research findings. Design and Development Research is appropriate for both experienced researchers and those preparing to become researchers. It is intended for scholars interested in planning and conducting design and development research, and is intended to stimulate future thinking about methods, strategies, and issues related to the field.

The National Children's Study Research Plan

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Publisher : National Academies Press
ISBN 13 : 030912056X
Total Pages : 166 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The National Children's Study Research Plan by : National Research Council

Download or read book The National Children's Study Research Plan written by National Research Council and published by National Academies Press. This book was released on 2008-08-16 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Children's Study (NCS) is planned to be the largest long-term study of environmental and genetic effects on children's health ever conducted in the United States. It proposes to examine the effects of environmental influences on the health and development of approximately 100,000 children across the United States, following them from before birth until age 21. By archiving all of the data collected, the NCS is intended to provide a valuable resource for analyses conducted many years into the future. This book evaluates the research plan for the NCS, by assessing the scientific rigor of the study and the extent to which it is being carried out with methods, measures, and collection of data and specimens to maximize the scientific yield of the study. The book concludes that if the NCS is conducted as proposed, the database derived from the study should be valuable for investigating hypotheses described in the research plan as well as additional hypotheses that will evolve. Nevertheless, there are important weaknesses and shortcomings in the research plan that diminish the study's expected value below what it might be.

Educational Design Research

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Publisher : Routledge
ISBN 13 : 1134155654
Total Pages : 177 pages
Book Rating : 4.1/5 (341 download)

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Book Synopsis Educational Design Research by : Jan Van den Akker

Download or read book Educational Design Research written by Jan Van den Akker and published by Routledge. This book was released on 2006-11-22 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of design research has been gaining momentum over the last five years, particularly in educational studies. As papers and articles have grown in number, definition of the domain is now beginning to standardise. This book fulfils a growing need by providing a synthesised assessment of the use of development research in education. It looks at four main elements: background information including origins, definitions of development research, description of applications and benefits and risks associated with studies of this kind how the approach can serve the design of learning environments and educational technology quality assurance - how to safeguard academic rigor while conducting design and development studies a synthesis and overview of the topic along with relevant reflections.

Understanding by Design

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Publisher : ASCD
ISBN 13 : 1416600353
Total Pages : 383 pages
Book Rating : 4.4/5 (166 download)

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Book Synopsis Understanding by Design by : Grant P. Wiggins

Download or read book Understanding by Design written by Grant P. Wiggins and published by ASCD. This book was released on 2005 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is understanding and how does it differ from knowledge? How can we determine the big ideas worth understanding? Why is understanding an important teaching goal, and how do we know when students have attained it? How can we create a rigorous and engaging curriculum that focuses on understanding and leads to improved student performance in today's high-stakes, standards-based environment? Authors Grant Wiggins and Jay McTighe answer these and many other questions in this second edition of Understanding by Design. Drawing on feedback from thousands of educators around the world who have used the UbD framework since its introduction in 1998, the authors have greatly revised and expanded their original work to guide educators across the K-16 spectrum in the design of curriculum, assessment, and instruction. With an improved UbD Template at its core, the book explains the rationale of backward design and explores in greater depth the meaning of such key ideas as essential questions and transfer tasks. Readers will learn why the familiar coverage- and activity-based approaches to curriculum design fall short, and how a focus on the six facets of understanding can enrich student learning. With an expanded array of practical strategies, tools, and examples from all subject areas, the book demonstrates how the research-based principles of Understanding by Design apply to district frameworks as well as to individual units of curriculum. Combining provocative ideas, thoughtful analysis, and tested approaches, this new edition of Understanding by Design offers teacher-designers a clear path to the creation of curriculum that ensures better learning and a more stimulating experience for students and teachers alike.

Intervention Research

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Publisher : Springer Publishing Company
ISBN 13 : 0826109586
Total Pages : 498 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Intervention Research by : Bernadette Mazurek Melnyk, PhD, APRN-CNP, FAANP, FNAP, FAAN

Download or read book Intervention Research written by Bernadette Mazurek Melnyk, PhD, APRN-CNP, FAANP, FNAP, FAAN and published by Springer Publishing Company. This book was released on 2012-04-23 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2012 First Place AJN Book of the Year Award Winner in Nursing Research! "This is a resource for success and should be a part of any researcher's library."--Doody's Medical Reviews This book is a practical, user-friendly guide for health care researchers across multiple disciplines who are involved in intervention research. It provides all of the essential elements needed for understanding how to design, conduct, analyze, and fund intervention studies that are replicable and can withstand the scrutiny of the Institutional Review Board and peer review. Developed from an annual continuing education workshop on intervention studies conducted by Dr. Melnyk, this text is the most comprehensive body of information available on this topic. Contributors address the design of interventions that are ethically considerate and sensitive to culture, race/ethnicity, and gender, minimizing threats to external and internal validity, measurement, and budgeting. The guide explores such implementation issues as subject recruitment and retention, data management, and specialized settings, cost analysis, and explaining intervention effects. The text also guides readers in writing grant applications that fund , and addresses how to move intervention study findings into the real world. A unique addition to the book is the availability of digital examples of progress reports, final reports, and research grant applications that have received funding from the National Institutes of Health and other relevant organizations. This text is a valuable resource for all health care professionals conducting research and for doctoral students in health care studies. Key Features: Presents the essential tools for designing, conducting, analyzing, and funding intervention studies Designed for use by health care professionals conducting intervention research Provides comprehensive, accessible guidelines for doctoral students across all health care disciplines Instructs readers on writing grant applications that fund Includes digital examples of funded research grants, progress reports, and final reports

Equal Educational Opportunity

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Author :
Publisher :
ISBN 13 :
Total Pages : 542 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Equal Educational Opportunity by : United States. Congress. Senate. Select Committee on Equal Educational Opportunity

Download or read book Equal Educational Opportunity written by United States. Congress. Senate. Select Committee on Equal Educational Opportunity and published by . This book was released on 1970 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Cambridge Handbook of Computing Education Research

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Publisher : Cambridge University Press
ISBN 13 : 1108755704
Total Pages : 1180 pages
Book Rating : 4.1/5 (87 download)

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Book Synopsis The Cambridge Handbook of Computing Education Research by : Sally A. Fincher

Download or read book The Cambridge Handbook of Computing Education Research written by Sally A. Fincher and published by Cambridge University Press. This book was released on 2019-02-21 with total page 1180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook describes the extent and shape of computing education research today. Over fifty leading researchers from academia and industry (including Google and Microsoft) have contributed chapters that together define and expand the evidence base. The foundational chapters set the field in context, articulate expertise from key disciplines, and form a practical guide for new researchers. They address what can be learned empirically, methodologically and theoretically from each area. The topic chapters explore issues that are of current interest, why they matter, and what is already known. They include discussion of motivational context, implications for practice, and open questions which might suggest future research. The authors provide an authoritative introduction to the field which is essential reading for policy makers, as well as both new and established researchers.

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

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Author :
Publisher : Government Printing Office
ISBN 13 : 1587634236
Total Pages : 236 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide by : Agency for Health Care Research and Quality (U.S.)

Download or read book Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide written by Agency for Health Care Research and Quality (U.S.) and published by Government Printing Office. This book was released on 2013-02-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Improving Health Research on Small Populations

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Publisher : National Academies Press
ISBN 13 : 0309476097
Total Pages : 151 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Improving Health Research on Small Populations by : National Academies of Sciences, Engineering, and Medicine

Download or read book Improving Health Research on Small Populations written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-08-02 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing diversity of population of the United States presents many challenges to conducting health research that is representative and informative. Dispersion and accessibility issues can increase logistical costs; populations for which it is difficult to obtain adequate sample size are also likely to be expensive to study. Hence, even if it is technically feasible to study a small population, it may not be easy to obtain the funding to do so. In order to address the issues associated with improving health research of small populations, the National Academies of Sciences, Engineering, and Medicine convened a workshop in January 2018. Participants considered ways of addressing the challenges of conducting epidemiological studies or intervention research with small population groups, including alternative study designs, innovative methodologies for data collection, and innovative statistical techniques for analysis.

Research Design

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Publisher : SAGE
ISBN 13 : 1452226105
Total Pages : 305 pages
Book Rating : 4.4/5 (522 download)

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Book Synopsis Research Design by : John W. Creswell

Download or read book Research Design written by John W. Creswell and published by SAGE. This book was released on 2014 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bestseller that pioneered the comparison of qualitative, quantitative, and mixed methods research design continues in its Fourth Edition to help students and researchers prepare their plan or proposal for a scholarly journal article, dissertation or thesis.

Encyclopedia of Research Design

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Author :
Publisher : SAGE
ISBN 13 : 1412961270
Total Pages : 1779 pages
Book Rating : 4.4/5 (129 download)

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Book Synopsis Encyclopedia of Research Design by : Neil J. Salkind

Download or read book Encyclopedia of Research Design written by Neil J. Salkind and published by SAGE. This book was released on 2010-06-22 with total page 1779 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Comprising more than 500 entries, the Encyclopedia of Research Design explains how to make decisions about research design, undertake research projects in an ethical manner, interpret and draw valid inferences from data, and evaluate experiment design strategies and results. Two additional features carry this encyclopedia far above other works in the field: bibliographic entries devoted to significant articles in the history of research design and reviews of contemporary tools, such as software and statistical procedures, used to analyze results. It covers the spectrum of research design strategies, from material presented in introductory classes to topics necessary in graduate research; it addresses cross- and multidisciplinary research needs, with many examples drawn from the social and behavioral sciences, neurosciences, and biomedical and life sciences; it provides summaries of advantages and disadvantages of often-used strategies; and it uses hundreds of sample tables, figures, and equations based on real-life cases."--Publisher's description.

Hearings, Reports and Prints of the Senate Select Committee on Equal Educational Opportunity

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Author :
Publisher :
ISBN 13 :
Total Pages : 1030 pages
Book Rating : 4.:/5 (36 download)

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Book Synopsis Hearings, Reports and Prints of the Senate Select Committee on Equal Educational Opportunity by : United States. Congress. Senate. Select Committee on Equal Educational Opportunity

Download or read book Hearings, Reports and Prints of the Senate Select Committee on Equal Educational Opportunity written by United States. Congress. Senate. Select Committee on Equal Educational Opportunity and published by . This book was released on 1972 with total page 1030 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Practical Research

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Publisher :
ISBN 13 : 9781292021171
Total Pages : 384 pages
Book Rating : 4.0/5 (211 download)

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Book Synopsis Practical Research by : Paul D. Leedy

Download or read book Practical Research written by Paul D. Leedy and published by . This book was released on 2013-07-30 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: For undergraduate or graduate courses that include planning, conducting, and evaluating research. A do-it-yourself, understand-it-yourself manual designed to help students understand the fundamental structure of research and the methodical process that leads to valid, reliable results. Written in uncommonly engaging and elegant prose, this text guides the reader, step-by-step, from the selection of a problem, through the process of conducting authentic research, to the preparation of a completed report, with practical suggestions based on a solid theoretical framework and sound pedagogy. Suitable as the core text in any introductory research course or even for self-instruction, this text will show students two things: 1) that quality research demands planning and design; and, 2) how their own research projects can be executed effectively and professionally.