Statistical Development of Quality in Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 9780470515891
Total Pages : 280 pages
Book Rating : 4.5/5 (158 download)

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Book Synopsis Statistical Development of Quality in Medicine by : Per Winkel

Download or read book Statistical Development of Quality in Medicine written by Per Winkel and published by John Wiley & Sons. This book was released on 2007-06-13 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The promotion of standards and guidelines to advance quality assurance and control is an integral part of the health care sector. Quantitative methods are needed to monitor, control and improve the quality of medical processes. Statistical Development of Quality in Medicine presents the statistical concepts behind the application of industrial quality control methods. Filled with numerous case studies and worked examples, the text enables the reader to choose the relevant control chart, to critically apply it, improve it if necessary, and monitor its stability. Furthermore, the reader is provided with the necessary background to critically assess the literature on the application of control charts and risk adjustment and to apply the findings. Contains a user-friendly introduction, setting out the necessary statistical concepts used in the field. Uses numerous real-life case studies from the literature and the authors’ own research as the backbone of the text. Provides a supplementary website featuring problems and answers drawn from the book, alongside examples in Statgraphics. The accessible style of Statistical Development of in Clinical Medicine invites a large readership. It is primarily aimed at health care officials, and personnel responsible for developing and controlling the quality of health care services. However, it is also ideal for statisticians working with health care problems, diagnostic and pharmaceutical companies, and graduate students of quality control.

Frontiers in Statistical Quality Control 9

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Publisher : Springer Science & Business Media
ISBN 13 : 3790823805
Total Pages : 367 pages
Book Rating : 4.7/5 (98 download)

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Book Synopsis Frontiers in Statistical Quality Control 9 by : Hans-Joachim Lenz

Download or read book Frontiers in Statistical Quality Control 9 written by Hans-Joachim Lenz and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: The twenty-three papers in this volume are carefully selected, reviewed and revised for this volume, and are divided into two parts: Part 1: "On-line Control" with subchapters 1.1 "Control Charts" and 1.2 "Surveillance Sampling and Sampling Plans" and Part 2:"Off-line Control".

Statistical Methods for Evaluating Safety in Medical Product Development

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Publisher : John Wiley & Sons
ISBN 13 : 1118763092
Total Pages : 392 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Statistical Methods for Evaluating Safety in Medical Product Development by : A. Lawrence Gould

Download or read book Statistical Methods for Evaluating Safety in Medical Product Development written by A. Lawrence Gould and published by John Wiley & Sons. This book was released on 2014-12-08 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during medical product development. Each chapter provides sufficient detail to the reader to undertake the design and analysis of experiments at various stages of product development, including comprehensive references to the relevant literature. Provides a guide to statistical methods and application in medical product development Assists readers in undertaking design and analysis of experiments at various stages of product development Features case studies throughout the book, as well as, SAS and R code

Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies

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Publisher : OECD Publishing
ISBN 13 : 9264805907
Total Pages : 447 pages
Book Rating : 4.2/5 (648 download)

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Book Synopsis Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies by : OECD

Download or read book Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies written by OECD and published by OECD Publishing. This book was released on 2019-10-17 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies.

Statistical Methods in Healthcare

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Publisher : John Wiley & Sons
ISBN 13 : 1119942047
Total Pages : 533 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Statistical Methods in Healthcare by : Frederick W. Faltin

Download or read book Statistical Methods in Healthcare written by Frederick W. Faltin and published by John Wiley & Sons. This book was released on 2012-07-24 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Methods in Healthcare In recent years the number of innovative medicinal products and devices submitted and approved by regulatory bodies has declined dramatically. The medical product development process is no longer able to keep pace with increasing technologies, science and innovations and the goal is to develop new scientific and technical tools and to make product development processes more efficient and effective. Statistical Methods in Healthcare focuses on the application of statistical methodologies to evaluate promising alternatives and to optimize the performance and demonstrate the effectiveness of those that warrant pursuit is critical to success. Statistical methods used in planning, delivering and monitoring health care, as well as selected statistical aspects of the development and/or production of pharmaceuticals and medical devices are also addressed. With a focus on finding solutions to these challenges, this book: Provides a comprehensive, in-depth treatment of statistical methods in healthcare, along with a reference source for practitioners and specialists in health care and drug development. Offers a broad coverage of standards and established methods through leading edge techniques. Uses an integrated case study based approach, with focus on applications. Looks at the use of analytical and monitoring schemes to evaluate therapeutic performance. Features the application of modern quality management systems to clinical practice, and to pharmaceutical development and production processes. Addresses the use of modern statistical methods such as Adaptive Design, Seamless Design, Data Mining, Bayesian networks and Bootstrapping that can be applied to support the challenging new vision. Practitioners in healthcare-related professions, ranging from clinical trials to care delivery to medical device design, as well as statistical researchers in the field, will benefit from this book.

Statistical Methods for Trend Detection and Analysis in the Environmental Sciences

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Publisher : John Wiley & Sons
ISBN 13 : 111999196X
Total Pages : 348 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Statistical Methods for Trend Detection and Analysis in the Environmental Sciences by : Richard Chandler

Download or read book Statistical Methods for Trend Detection and Analysis in the Environmental Sciences written by Richard Chandler and published by John Wiley & Sons. This book was released on 2011-03-25 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need to understand and quantify change is fundamental throughout the environmental sciences. This might involve describing past variation, understanding the mechanisms underlying observed changes, making projections of possible future change, or monitoring the effect of intervening in some environmental system. This book provides an overview of modern statistical techniques that may be relevant in problems of this nature. Practitioners studying environmental change will be familiar with many classical statistical procedures for the detection and estimation of trends. However, the ever increasing capacity to collect and process vast amounts of environmental information has led to growing awareness that such procedures are limited in the insights that they can deliver. At the same time, significant developments in statistical methodology have often been widely dispersed in the statistical literature and have therefore received limited exposure in the environmental science community. This book aims to provide a thorough but accessible review of these developments. It is split into two parts: the first provides an introduction to this area and the second part presents a collection of case studies illustrating the practical application of modern statistical approaches to the analysis of trends in real studies. Key Features: Presents a thorough introduction to the practical application and methodology of trend analysis in environmental science. Explores non-parametric estimation and testing as well as parametric techniques. Methods are illustrated using case studies from a variety of environmental application areas. Looks at trends in all aspects of a process including mean, percentiles and extremes. Supported by an accompanying website featuring datasets and R code. The book is designed to be accessible to readers with some basic statistical training, but also contains sufficient detail to serve as a reference for practising statisticians. It will therefore be of use to postgraduate students and researchers both in the environmental sciences and in statistics.

Statistical DNA Forensics

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Publisher : John Wiley & Sons
ISBN 13 : 9780470727034
Total Pages : 262 pages
Book Rating : 4.7/5 (27 download)

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Book Synopsis Statistical DNA Forensics by : Wing Kam Fung

Download or read book Statistical DNA Forensics written by Wing Kam Fung and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical methodology plays a key role in ensuring that DNA evidence is collected, interpreted, analyzed and presented correctly. With the recent advances in computer technology, this methodology is more complex than ever before. There are a growing number of books in the area but none are devoted to the computational analysis of evidence. This book presents the methodology of statistical DNA forensics with an emphasis on the use of computational techniques to analyze and interpret forensic evidence.

A Practical Guide to Designing Phase II Trials in Oncology

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Publisher : John Wiley & Sons
ISBN 13 : 1118570901
Total Pages : 260 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis A Practical Guide to Designing Phase II Trials in Oncology by : Sarah R. Brown

Download or read book A Practical Guide to Designing Phase II Trials in Oncology written by Sarah R. Brown and published by John Wiley & Sons. This book was released on 2014-05-12 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to identify optimal phase II trial designs Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, A Practical Guide to Designing Phase II Trials in Oncology sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomization, and considering both academic and industry perspectives. A comprehensive and systematic library of available phase II trial designs is included, saving time otherwise spent considering multiple manuscripts, and real-life practical examples of using this approach to design phase II trials in cancer are given. A Practical Guide to Designing Phase II Trials in Oncology: Offers a structured and practical approach to phase II trial design Considers trial design from both an academic and industry perspective Includes a structured library of available phase II trial designs Is relevant to both clinical and statistical researchers at all levels Includes real life examples of applying this approach For those new to trial design, A Practical Guide to Designing Phase II Trials in Oncology will be a unique and practical learning tool, providing an introduction to the concepts behind informed decision making in phase II trials. For more experienced practitioners, the book will offer an overview of new, less familiar approaches to phase II trial design, providing alternative options to those which they may have previously used.

Geostatistics for Environmental Scientists

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Publisher : John Wiley & Sons
ISBN 13 : 9780470517260
Total Pages : 330 pages
Book Rating : 4.5/5 (172 download)

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Book Synopsis Geostatistics for Environmental Scientists by : Richard Webster

Download or read book Geostatistics for Environmental Scientists written by Richard Webster and published by John Wiley & Sons. This book was released on 2007-10-22 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Geostatistics is essential for environmental scientists. Weather and climate vary from place to place, soil varies at every scale at which it is examined, and even man-made attributes – such as the distribution of pollution – vary. The techniques used in geostatistics are ideally suited to the needs of environmental scientists, who use them to make the best of sparse data for prediction, and top plan future surveys when resources are limited. Geostatistical technology has advanced much in the last few years and many of these developments are being incorporated into the practitioner’s repertoire. This second edition describes these techniques for environmental scientists. Topics such as stochastic simulation, sampling, data screening, spatial covariances, the variogram and its modeling, and spatial prediction by kriging are described in rich detail. At each stage the underlying theory is fully explained, and the rationale behind the choices given, allowing the reader to appreciate the assumptions and constraints involved.

Statistical Methods in Diagnostic Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 1118626044
Total Pages : 597 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Statistical Methods in Diagnostic Medicine by : Xiao-Hua Zhou

Download or read book Statistical Methods in Diagnostic Medicine written by Xiao-Hua Zhou and published by John Wiley & Sons. This book was released on 2014-08-21 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the First Edition " . . . the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests in medical research In recent years, a considerable amount of research has focused on evolving methods for designing and analyzing diagnostic accuracy studies. Statistical Methods in Diagnostic Medicine, Second Edition continues to provide a comprehensive approach to the topic, guiding readers through the necessary practices for understanding these studies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy and study design, the authors successfully define various measures of diagnostic accuracy, describe strategies for designing diagnostic accuracy studies, and present key statistical methods for estimating and comparing test accuracy. Topics new to the Second Edition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values and sample size calculations Correcting techniques for verification and imperfect standard biases Sample size calculation for multiple reader studies when pilot data are available Updated meta-analysis methods, now incorporating random effects Three case studies thoroughly showcase some of the questions and statistical issues that arise in diagnostic medicine, with all associated data provided in detailed appendices. A related web site features Fortran, SAS®, and R software packages so that readers can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is an excellent supplement for biostatistics courses at the graduate level. It also serves as a valuable reference for clinicians and researchers working in the fields of medicine, epidemiology, and biostatistics.

Registries for Evaluating Patient Outcomes

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Publisher : Government Printing Office
ISBN 13 : 1587634333
Total Pages : 396 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Registries for Evaluating Patient Outcomes by : Agency for Healthcare Research and Quality/AHRQ

Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.

Disease Control Priorities in Developing Countries

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Publisher : World Bank Publications
ISBN 13 : 0821361805
Total Pages : 1449 pages
Book Rating : 4.8/5 (213 download)

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Book Synopsis Disease Control Priorities in Developing Countries by : Dean T. Jamison

Download or read book Disease Control Priorities in Developing Countries written by Dean T. Jamison and published by World Bank Publications. This book was released on 2006-04-02 with total page 1449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

Quantitative Methods for Traditional Chinese Medicine Development

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Publisher : CRC Press
ISBN 13 : 1482236001
Total Pages : 433 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Quantitative Methods for Traditional Chinese Medicine Development by : Shein-Chung Chow

Download or read book Quantitative Methods for Traditional Chinese Medicine Development written by Shein-Chung Chow and published by CRC Press. This book was released on 2015-10-15 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, many pharmaceutical companies and clinical research organizations have been focusing on the development of traditional Chinese (herbal) medicines (TCMs) as alternatives to treating critical or life-threatening diseases and as pathways to personalized medicine. Quantitative Methods for Traditional Chinese Medicine Development is the first book entirely devoted to the design and analysis of TCM development from a Western perspective, i.e., evidence-based clinical research and development. The book provides not only a comprehensive summary of innovative quantitative methods for developing TCMs but also a useful desk reference for principal investigators involved in personalized medicine. Written by one of the world's most prominent biostatistics researchers, the book connects the pharmaceutical industry, regulatory agencies, and academia. It presents a state-of-the-art examination of the subject for: Scientists and researchers who are engaged in pharmaceutical/clinical research and development of TCMs Those in regulatory agencies who make decisions in the review and approval process of TCM regulatory submissions Biostatisticians who provide statistical support to assess clinical safety and effectiveness of TCMs and related issues regarding quality control and assurance as well as to test for consistency in the manufacturing processes for TCMs This book covers all of the statistical issues encountered at various stages of pharmaceutical/clinical development of a TCM. It explains regulatory requirements; product specifications and standards; and various statistical techniques for evaluation of TCMs, validation of diagnostic procedures, and testing consistency

Principles and Methods of Quality Management in Health Care

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Publisher : Jones & Bartlett Learning
ISBN 13 : 9780834218611
Total Pages : 490 pages
Book Rating : 4.2/5 (186 download)

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Book Synopsis Principles and Methods of Quality Management in Health Care by : Donald E. Lighter

Download or read book Principles and Methods of Quality Management in Health Care written by Donald E. Lighter and published by Jones & Bartlett Learning. This book was released on 2000 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concentrating on quantitative methods for proper quality improvement documentation, the authors explain the processes for improving quality assurance among health care providers. Topics covered include group processes, statistical process control, clinical practice guidelines, care management, the l

Beyond the HIPAA Privacy Rule

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Publisher : National Academies Press
ISBN 13 : 0309124999
Total Pages : 334 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Beyond the HIPAA Privacy Rule by : Institute of Medicine

Download or read book Beyond the HIPAA Privacy Rule written by Institute of Medicine and published by National Academies Press. This book was released on 2009-03-24 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the realm of health care, privacy protections are needed to preserve patients' dignity and prevent possible harms. Ten years ago, to address these concerns as well as set guidelines for ethical health research, Congress called for a set of federal standards now known as the HIPAA Privacy Rule. In its 2009 report, Beyond the HIPAA Privacy Rule: Enhancing Privacy, Improving Health Through Research, the Institute of Medicine's Committee on Health Research and the Privacy of Health Information concludes that the HIPAA Privacy Rule does not protect privacy as well as it should, and that it impedes important health research.

Secondary Analysis of Electronic Health Records

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Publisher : Springer
ISBN 13 : 3319437429
Total Pages : 427 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Secondary Analysis of Electronic Health Records by : MIT Critical Data

Download or read book Secondary Analysis of Electronic Health Records written by MIT Critical Data and published by Springer. This book was released on 2016-09-09 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.

Statistical Methods for Quality of Life Studies

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Publisher : Springer Science & Business Media
ISBN 13 : 1475736258
Total Pages : 358 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Statistical Methods for Quality of Life Studies by : Mounir Mesbah

Download or read book Statistical Methods for Quality of Life Studies written by Mounir Mesbah and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: On October 16 and 17, 2000, we hosted an international workshop entitled "Statistical Design, Measurement, and Analysis of Health Related Quality of Life." The workshop was held in the beautiful city of Arradon, South Brittany, France with the main goal of fostering an interdisciplinary forum for discussion of theoretical and applied statistical issues arising in studies of health-related quality of life (HRQoL). Included were biostatisticians, psychometricians and public health professionals (e.g., physicians, sociologists, psychologists) active in the study ofHRQoL. In assembling this volume, we invited each conference participant to contribute a paper based on his or her presentation and the ensuing and very interesting discussions that took place in Arradon. All papers were peer-reviewed, by anonymous reviewers, and revised before final editing and acceptance. Although this process was quite time consuming, we believe that it greatly improved the volume as a whole, making this book a valuable contribution to the field ofHRQoL research. The volume presents a broad spectrum of papers presented at the Workshop, and thus illustrates the range of current research related to the theory, methods and applications of HRQoL, as well as the interdisciplinary nature ofthis work. Following an introduction written by Sir David Cox, it includes 27 articles organized into the following chapters.