Sex and Gender Differences in Pharmacology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642307264
Total Pages : 599 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Sex and Gender Differences in Pharmacology by : Vera Regitz-Zagrosek

Download or read book Sex and Gender Differences in Pharmacology written by Vera Regitz-Zagrosek and published by Springer Science & Business Media. This book was released on 2012-10-02 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.

Sex and Gender Effects in Pharmacology

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Publisher : Springer Nature
ISBN 13 : 3031426487
Total Pages : 286 pages
Book Rating : 4.0/5 (314 download)

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Book Synopsis Sex and Gender Effects in Pharmacology by : Stella E. Tsirka

Download or read book Sex and Gender Effects in Pharmacology written by Stella E. Tsirka and published by Springer Nature. This book was released on 2023-11-12 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.

Sex and Gender Differences in Pharmacology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642307256
Total Pages : 599 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Sex and Gender Differences in Pharmacology by : Vera Regitz-Zagrosek

Download or read book Sex and Gender Differences in Pharmacology written by Vera Regitz-Zagrosek and published by Springer Science & Business Media. This book was released on 2012-10-02 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: A trailblazing assessment of sex and gender differences in reactions to drug therapy, this volume reflects the topic’s growing recognition. Analyses by international experts on both pharmacokinetics and drug development are informed by an extensive data set.

How Sex and Gender Impact Clinical Practice

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Publisher : Academic Press
ISBN 13 : 0128167505
Total Pages : 361 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis How Sex and Gender Impact Clinical Practice by : Marjorie R. Jenkins

Download or read book How Sex and Gender Impact Clinical Practice written by Marjorie R. Jenkins and published by Academic Press. This book was released on 2020-12-02 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease. Explores the effects of sex and gender on disease presentation, treatment and prognosis, and how these differences influence clinical decision-making Provides practical guidance that helps clinicians implement a more individualized approach to patient care Contains information on diseases in each major specialty, as well as chapters on communication, pharmacology and public health challenges

Psychopharmacology and Women

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Publisher : American Psychiatric Publishing
ISBN 13 :
Total Pages : 624 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Psychopharmacology and Women by : Margaret F. Jensvold

Download or read book Psychopharmacology and Women written by Margaret F. Jensvold and published by American Psychiatric Publishing. This book was released on 1996 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Psychopharmacology and Women: Sex, Gender and HormoHHnes" brings together in one volume much of the information currently available on sex-related factors in psychopharmacology. Chapters by recognised leaders in the field cover topics such as basic pharmacokinetic mechanisms of psychotropics in women, associations among endogenous hormones and neurotransmitters, and interactions of psychotropics with exogenous sex steroid hormones to psychopharmacological considerations relating to the menstrual cycle, pregnancy and lactation, and the menopause. In addition to providing comprehensive reviews of new theories and treatments, chapter authors point out where gaps in knowledge remain.

Drug Discovery and Evaluation: Methods in Clinical Pharmacology

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Publisher : Springer Science & Business Media
ISBN 13 : 3540898905
Total Pages : 576 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Drug Discovery and Evaluation: Methods in Clinical Pharmacology by : H.Gerhard Vogel

Download or read book Drug Discovery and Evaluation: Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".

Sex and Gender in Acute Care Medicine

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Publisher : Cambridge University Press
ISBN 13 : 1107668166
Total Pages : 265 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Sex and Gender in Acute Care Medicine by : Alyson J. McGregor

Download or read book Sex and Gender in Acute Care Medicine written by Alyson J. McGregor and published by Cambridge University Press. This book was released on 2016-05-20 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the issue of sex and gender in the evaluation and treatment of patients in delivering acute medical care.

Sex and Gender Aspects in Clinical Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 9780857298324
Total Pages : 204 pages
Book Rating : 4.2/5 (983 download)

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Book Synopsis Sex and Gender Aspects in Clinical Medicine by : Sabine Oertelt-Prigione

Download or read book Sex and Gender Aspects in Clinical Medicine written by Sabine Oertelt-Prigione and published by Springer Science & Business Media. This book was released on 2011-11-15 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.

Sex and Gender Differences in Infection and Treatments for Infectious Diseases

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Publisher : Springer Nature
ISBN 13 : 3031351398
Total Pages : 282 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Sex and Gender Differences in Infection and Treatments for Infectious Diseases by : Sabra L. Klein

Download or read book Sex and Gender Differences in Infection and Treatments for Infectious Diseases written by Sabra L. Klein and published by Springer Nature. This book was released on 2023-09-11 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully revised and significantly expanded second edition examines sex and gender differences in the immune system's response to bacterial, viral, and parasitic infections. The volume discusses both common and distinct molecular mechanisms that mediate these differences and illustrates how responses to vaccines may differ between the sexes and in pregnant individuals. Special emphasis is placed on the interplay between hormones and the immune system in the pathogenesis of HIV, SARS-CoV-2, influenza, malaria, tuberculosis, and amebiasis. This second edition includes completely rewritten chapters as well as all new contents. This book is intended for researchers in academia and industry as well as clinicians in the fields of microbiology, immunology, and pharmacology. By expanding knowledge in sex and gender medicine as a basis for developing personalized treatment strategies, the book contributes to UN Sustainable Development Goals 3 (health and well-being) and 5 (gender equality).

Sex, Gender and Substance Use

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Publisher : MDPI
ISBN 13 : 3036502009
Total Pages : 272 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Sex, Gender and Substance Use by : Lorraine Greaves

Download or read book Sex, Gender and Substance Use written by Lorraine Greaves and published by MDPI. This book was released on 2021-04-14 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Sex, Gender and Substance Use” describes how both biological and social factors affect people's use of substances. There is a lot of research carried out on substance use, prevention and treatment in which sex and gender are missing. This book describes the concepts of sex and gender, what they mean and why including them in substance use research, practice and policy is vital. Substances such as alcohol, drugs, nicotine, and tobacco all have differential effects on females and males. Social and cultural gendered factors affect how women and men react to prevention, treatment and policies. The book includes numerous examples of how sex- and gender-sensitive research can increase our understanding and improve prevention and treatment, and why striving for gender-transformative substance use practice and research remains a gold standard.

Principles of Gender-Specific Medicine

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Publisher : Academic Press
ISBN 13 : 0128035420
Total Pages : 792 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Gender-Specific Medicine by : Marianne J. Legato

Download or read book Principles of Gender-Specific Medicine written by Marianne J. Legato and published by Academic Press. This book was released on 2017-05-15 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols

Sex and Gender in Biomedicine

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Publisher : Universitätsverlag Göttingen
ISBN 13 : 3941875264
Total Pages : 131 pages
Book Rating : 4.9/5 (418 download)

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Book Synopsis Sex and Gender in Biomedicine by : Gesine Thea Klinge

Download or read book Sex and Gender in Biomedicine written by Gesine Thea Klinge and published by Universitätsverlag Göttingen. This book was released on 2010 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sex and gender in biomedicine are innovative research concepts of theoretical and clinical medicine that enable a better understanding of health and disease, evidence-based knowledge, effective therapies, and better health outcomes for women and men. Gender Medicine stimulates new ways of doing research: that is to consider sex and gender at all levels of research, from basic research into gene polymorphisms to health behaviour. New research questions have been put forward that focus not on differences per se but on the development of differences. In this book, contributions from the field of neuroscience, addiction research, and organ transplantation exemplify concepts, approaches, methods and results in the field.

Why Gender Matters

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Publisher : Harmony
ISBN 13 : 0307419584
Total Pages : 338 pages
Book Rating : 4.3/5 (74 download)

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Book Synopsis Why Gender Matters by : Leonard Sax, M.D., Ph.D.

Download or read book Why Gender Matters written by Leonard Sax, M.D., Ph.D. and published by Harmony. This book was released on 2007-12-18 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are boys and girls really that different? Twenty years ago, doctors and researchers didn’t think so. Back then, most experts believed that differences in how girls and boys behave are mainly due to differences in how they were treated by their parents, teachers, and friends. It's hard to cling to that belief today. An avalanche of research over the past twenty years has shown that sex differences are more significant and profound than anybody guessed. Sex differences are real, biologically programmed, and important to how children are raised, disciplined, and educated. In Why Gender Matters, psychologist and family physician Dr. Leonard Sax leads parents through the mystifying world of gender differences by explaining the biologically different ways in which children think, feel, and act. He addresses a host of issues, including discipline, learning, risk taking, aggression, sex, and drugs, and shows how boys and girls react in predictable ways to different situations. For example, girls are born with more sensitive hearing than boys, and those differences increase as kids grow up. So when a grown man speaks to a girl in what he thinks is a normal voice, she may hear it as yelling. Conversely, boys who appear to be inattentive in class may just be sitting too far away to hear the teacher—especially if the teacher is female. Likewise, negative emotions are seated in an ancient structure of the brain called the amygdala. Girls develop an early connection between this area and the cerebral cortex, enabling them to talk about their feelings. In boys these links develop later. So if you ask a troubled adolescent boy to tell you what his feelings are, he often literally cannot say. Dr. Sax offers fresh approaches to disciplining children, as well as gender-specific ways to help girls and boys avoid drugs and early sexual activity. He wants parents to understand and work with hardwired differences in children, but he also encourages them to push beyond gender-based stereotypes. A leading proponent of single-sex education, Dr. Sax points out specific instances where keeping boys and girls separate in the classroom has yielded striking educational, social, and interpersonal benefits. Despite the view of many educators and experts on child-rearing that sex differences should be ignored or overcome, parents and teachers would do better to recognize, understand, and make use of the biological differences that make a girl a girl, and a boy a boy.

Principles of Gender-Specific Medicine

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Publisher : Academic Press
ISBN 13 : 0080921507
Total Pages : 797 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Principles of Gender-Specific Medicine by : Marianne Legato J

Download or read book Principles of Gender-Specific Medicine written by Marianne Legato J and published by Academic Press. This book was released on 2009-10-29 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of gender-specific medicine examines how normal human biology and physiology differ between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing research covers various conditions that predominantly occur in men as well conditions that predominantly occur in women. Among the areas of greatest difference are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabetes, obesity, and infectious diseases. The Second Edition of Principles of Gender-Specific Medicine focuses on the essentials of gender-specific medicine and the current study of sex and gender differences in human physiology and pathophysiology. New section editors, new chapter authors, and new chapters have been added to reflect the most up-to-date clinical research and practice. Offers insight into how the gender-specific risks of one organ system’s disease affects the health of other organ systems Outlines the sex-specific differences of normal anatomy and physiology Illustrates the gender-specific features and quantifies "gender" and "sex" as risk factors across all major diseases Qualifies and analyzes the results of new drug therapies designed with gender-specific differences in mind: ex, hormone therapy in men and women for the prevention and treatment of cardiovascular disease All chapters progress translationally from the basic science to the clinical applications of gender-specific therapies, drugs, or treatments Sections on drug metabolism, aging, and meta-analysis of data incorporated into all disease-specific chapters

Exploring the Biological Contributions to Human Health

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Publisher : National Academies Press
ISBN 13 : 9780309132978
Total Pages : 288 pages
Book Rating : 4.1/5 (329 download)

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Book Synopsis Exploring the Biological Contributions to Human Health by : Institute of Medicine

Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Handbook of Clinical Gender Medicine

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805599307
Total Pages : 529 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Handbook of Clinical Gender Medicine by : K. Schenck-Gustafsson

Download or read book Handbook of Clinical Gender Medicine written by K. Schenck-Gustafsson and published by Karger Medical and Scientific Publishers. This book was released on 2012-08-17 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gender medicine is an important new field in health and disease. It is derived from top-quality research and encompasses the biological and social determinants that underlie the susceptibility to disease and its consequences. In the future, consideration of the role of gender will undoubtedly become an integral feature of all research and clinical care. Defining the role of gender in medicine requires a broad perspective on biology and diverse skills in biomedical and social sciences. When these scientific disciplines come together, a revolution in medical care is in the making. Covering twelve different areas of medicine, the practical and useful Handbook of Clinical Gender Medicine provides up-to-date information on the role of gender in the clinical presentation, diagnosis, and management of a wide range of common diseases.

Sex and Gender Differences in Neurological Disease

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Author :
Publisher : Academic Press
ISBN 13 : 0323915906
Total Pages : 394 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Sex and Gender Differences in Neurological Disease by :

Download or read book Sex and Gender Differences in Neurological Disease written by and published by Academic Press. This book was released on 2022-08-27 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review on Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in International Review on Neurobiology serials Updated release includes the latest information on Sex and Gender Differences in Neurological Disease