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Sex And Gender Differences In Pharmacology
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Book Synopsis Sex and Gender Differences in Pharmacology by : Vera Regitz-Zagrosek
Download or read book Sex and Gender Differences in Pharmacology written by Vera Regitz-Zagrosek and published by Springer Science & Business Media. This book was released on 2012-10-02 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.
Book Synopsis Sex and Gender Differences in Pharmacology by : Vera Regitz-Zagrosek
Download or read book Sex and Gender Differences in Pharmacology written by Vera Regitz-Zagrosek and published by Springer Science & Business Media. This book was released on 2012-10-02 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: A trailblazing assessment of sex and gender differences in reactions to drug therapy, this volume reflects the topic’s growing recognition. Analyses by international experts on both pharmacokinetics and drug development are informed by an extensive data set.
Book Synopsis Drug Discovery and Evaluation: Methods in Clinical Pharmacology by : H.Gerhard Vogel
Download or read book Drug Discovery and Evaluation: Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Book Synopsis Sex and Gender Effects in Pharmacology by : Stella E. Tsirka
Download or read book Sex and Gender Effects in Pharmacology written by Stella E. Tsirka and published by Springer Nature. This book was released on 2023-11-12 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.
Book Synopsis Psychopharmacology and Women by : Margaret F. Jensvold
Download or read book Psychopharmacology and Women written by Margaret F. Jensvold and published by American Psychiatric Publishing. This book was released on 1996 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Psychopharmacology and Women: Sex, Gender and HormoHHnes" brings together in one volume much of the information currently available on sex-related factors in psychopharmacology. Chapters by recognised leaders in the field cover topics such as basic pharmacokinetic mechanisms of psychotropics in women, associations among endogenous hormones and neurotransmitters, and interactions of psychotropics with exogenous sex steroid hormones to psychopharmacological considerations relating to the menstrual cycle, pregnancy and lactation, and the menopause. In addition to providing comprehensive reviews of new theories and treatments, chapter authors point out where gaps in knowledge remain.
Book Synopsis How Sex and Gender Impact Clinical Practice by : Marjorie R. Jenkins
Download or read book How Sex and Gender Impact Clinical Practice written by Marjorie R. Jenkins and published by Academic Press. This book was released on 2020-12-02 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease. Explores the effects of sex and gender on disease presentation, treatment and prognosis, and how these differences influence clinical decision-making Provides practical guidance that helps clinicians implement a more individualized approach to patient care Contains information on diseases in each major specialty, as well as chapters on communication, pharmacology and public health challenges
Book Synopsis Sex and Gender Differences in Infection and Treatments for Infectious Diseases by : Sabra L. Klein
Download or read book Sex and Gender Differences in Infection and Treatments for Infectious Diseases written by Sabra L. Klein and published by Springer Nature. This book was released on 2023-09-11 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully revised and significantly expanded second edition examines sex and gender differences in the immune system's response to bacterial, viral, and parasitic infections. The volume discusses both common and distinct molecular mechanisms that mediate these differences and illustrates how responses to vaccines may differ between the sexes and in pregnant individuals. Special emphasis is placed on the interplay between hormones and the immune system in the pathogenesis of HIV, SARS-CoV-2, influenza, malaria, tuberculosis, and amebiasis. This second edition includes completely rewritten chapters as well as all new contents. This book is intended for researchers in academia and industry as well as clinicians in the fields of microbiology, immunology, and pharmacology. By expanding knowledge in sex and gender medicine as a basis for developing personalized treatment strategies, the book contributes to UN Sustainable Development Goals 3 (health and well-being) and 5 (gender equality).
Book Synopsis Sex and Gender Differences in Alzheimer's Disease by : Maria Teresa Ferretti
Download or read book Sex and Gender Differences in Alzheimer's Disease written by Maria Teresa Ferretti and published by Academic Press. This book was released on 2021-07-23 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sex and Gender Differences in Alzheimer’s Disease: The Women’s Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer’s disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer’s disease families, in the frame of a precision medicine approach to Alzheimer’s disease.This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer’s disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer’s a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer’s disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer’s disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Endorsements/Reviews: "There is a clear sex and gender gap in outcomes for brain health disorders like Alzheimer’s disease, with strikingly negative outcomes for women. This understanding calls for a more systematic way of approaching this issue of inequality. This book effectively highlights and frames inequalities in all areas across the translational spectrum from bench-to-bedside and from boardroom-to-policy and economics. Closing the Brain Health Gap will help economies create recovery and prepare our systems for future global shocks." Harris A. Eyre MBBS, PhD, co-lead, Neuroscience-inspired Policy Initiative, OECD and PRODEO Institute. Instructor in Brain Health Diplomacy, Global Brain Health Institute, UCSF and TCD. "Sex and Gender Differences in Alzheimer's disease is the most important title to emerge on Alzheimer's disease in recent years.This comprehensive, multidisciplinary book is a must read for anyone with a serious interest in dementia prevention, diagnosis, treatment, care, cure and research. Precision medicine is the future of healthcare and this book represents an incredible and necessary resource to guide practice, policy and research in light of the fact that Alzheimer's disease disproportionately affects women. The combination of contributions from the most eminent experts and the most up-to-date research makes this an invaluable resource for clinicians, care providers, academics, researchers and policy makers. Given the complex nature of dementia and the multiple factors that influence risk and disease trajectory the scope of the book is both impressive and important covering sex differences in neurobiological processes, sex and gender differences in clinical aspects and gender differences linked to socioeconomic factors relevant to Alzheimer's disease. If you work in Alzheimer's disease, or indeed other dementias, then Sex and Gender Differences in Alzheimer's disease is a must have for your bookshelf." -- Sabina Brennan, PhD., C.Psychol.,PsSI., National representative for Ireland on Alzheimer Disease International's Medical and Scientific Advisory Panel
Book Synopsis Sex and Gender Bias in Technology and Artificial Intelligence by : Davide Cirillo
Download or read book Sex and Gender Bias in Technology and Artificial Intelligence written by Davide Cirillo and published by Academic Press. This book was released on 2022-05-21 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sex and Gender Bias in Technology and Artificial Intelligence: Biomedicine and Healthcare Applications details the integration of sex and gender as critical factors in innovative technologies (artificial intelligence, digital medicine, natural language processing, robotics) for biomedicine and healthcare applications. By systematically reviewing existing scientific literature, a multidisciplinary group of international experts analyze diverse aspects of the complex relationship between sex and gender, health and technology, providing a perspective overview of the pressing need of an ethically-informed science. The reader is guided through the latest implementations and insights in technological areas of accelerated growth, putting forward the neglected and overlooked aspects of sex and gender in biomedical research and healthcare solutions that leverage artificial intelligence, biosensors, and personalized medicine approaches to predict and prevent disease outcomes. The reader comes away with a critical understanding of this fundamental issue for the sake of better future technologies and more effective clinical approaches. First comprehensive title addressing the topic of sex and gender biases and artificial intelligence applications to biomedical research and healthcare Co-published by the Women’s Brain Project, a leading non-profit organization in this area Guides the reader through important topics like the Generation of Clinical Data, Clinical Trials, Big Data Analytics, Digital Biomarkers, Natural Language Processing
Author :Sabine Oertelt-Prigione Publisher :Springer Science & Business Media ISBN 13 :9780857298324 Total Pages :204 pages Book Rating :4.2/5 (983 download)
Book Synopsis Sex and Gender Aspects in Clinical Medicine by : Sabine Oertelt-Prigione
Download or read book Sex and Gender Aspects in Clinical Medicine written by Sabine Oertelt-Prigione and published by Springer Science & Business Media. This book was released on 2011-11-15 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.
Book Synopsis Principles of Gender-Specific Medicine by : Marianne J. Legato
Download or read book Principles of Gender-Specific Medicine written by Marianne J. Legato and published by Academic Press. This book was released on 2017-05-15 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols
Book Synopsis Pharmacology for Women's Health by : Mary C. Brucker
Download or read book Pharmacology for Women's Health written by Mary C. Brucker and published by Jones & Bartlett Publishers. This book was released on 2015-08 with total page 1230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Order of names reversed on previous edition.
Book Synopsis Sex and Gender Differences in Neurological Disease by :
Download or read book Sex and Gender Differences in Neurological Disease written by and published by Academic Press. This book was released on 2022-08-27 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review on Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in International Review on Neurobiology serials Updated release includes the latest information on Sex and Gender Differences in Neurological Disease
Author :K. Schenck-Gustafsson Publisher :Karger Medical and Scientific Publishers ISBN 13 :3805599307 Total Pages :538 pages Book Rating :4.8/5 (55 download)
Book Synopsis Handbook of Clinical Gender Medicine by : K. Schenck-Gustafsson
Download or read book Handbook of Clinical Gender Medicine written by K. Schenck-Gustafsson and published by Karger Medical and Scientific Publishers. This book was released on 2012-08-17 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gender medicine is an important new field in health and disease. It is derived from top-quality research and encompasses the biological and social determinants that underlie the susceptibility to disease and its consequences. In the future, consideration of the role of gender will undoubtedly become an integral feature of all research and clinical care. Defining the role of gender in medicine requires a broad perspective on biology and diverse skills in biomedical and social sciences. When these scientific disciplines come together, a revolution in medical care is in the making. Covering twelve different areas of medicine, the practical and useful Handbook of Clinical Gender Medicine provides up-to-date information on the role of gender in the clinical presentation, diagnosis, and management of a wide range of common diseases.
Download or read book Cardiac Drugs written by Kanu Chatterjee and published by JAYPEE BROTHERS PUBLISHERS. This book was released on 2013-12-15 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doody Rating : 3 stars : Cardiac drugs resource endows with the latest advances in cardiovascular pharmacology. Written by experts in cardiology from world renowned institutes, equipped with global view, signifying the best possible combination of clinical and research expertise in cardiovascular pharmacology. This is a comprehensive drug resource which provides up-to-date information on one of the most rapidly changing areas of medicine. Easy to follow, providing practical advice on how to manage cardiac diseases with a focus on hands-on therapeutic guidance for the clinicians. Text talks abo.
Book Synopsis Atkinson's Principles of Clinical Pharmacology by : Shiew-Mei Huang
Download or read book Atkinson's Principles of Clinical Pharmacology written by Shiew-Mei Huang and published by Academic Press. This book was released on 2021-10-16 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK
Book Synopsis General Considerations for the Clinical Evaluation of Drugs by : United States. Food and Drug Administration. Bureau of Drugs
Download or read book General Considerations for the Clinical Evaluation of Drugs written by United States. Food and Drug Administration. Bureau of Drugs and published by . This book was released on 1977 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
