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Download or read book Results and Problems in Cell Differentiation written by and published by . This book was released on 1975 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : W. Beermann
Publisher :
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.X/5 (1 download)
Download or read book Results and Problems in Cell Differentiation written by W. Beermann and published by . This book was released on 1968 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. Reinert
Publisher : Springer Science & Business Media
ISBN 13 : 354037390X
Total Pages : 336 pages
Book Rating : 4.5/5 (43 download)
Download or read book Cell Cycle and Cell Differentiation written by J. Reinert and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is instructive to compare the response of biologists to the two themes that comprise the title of this volume. The concept of the cell cycle-in contra distinction to cell division-is a relatively recent one. Nevertheless biologists of all persuasions appreciate and readily agree on the central problems in this area. Issues ranging from mechanisms that initiate and integrate the synthesis of chro mosomal proteins and DNA during S-phase of mitosis to the manner in which assembly of microtubules and their interactions lead to the segregation of metaphase chromosomes are readily followed by botanists and zoologists, as well as by cell and molecular biologists. These problems are crisp and well-defined. The current state of "cell differentiation" stands in sharp contrast. This, one of the oldest problems in experimental biology, almost defies definition today. The difficulties arise not only from a lack of pertinent information on the regulatory mechanisms, but also from conflicting basic concepts in this field. One of the ways in which this situation might be improved would be to find a broader experimental basis, including a better understanding of the relationship between the cell cycle and cell differentiation.
Author : Joan Abbott
Publisher : Springer
ISBN 13 : 3662350890
Total Pages : 163 pages
Book Rating : 4.6/5 (623 download)
Download or read book The Stability of the Differentiated State written by Joan Abbott and published by Springer. This book was released on 2013-11-11 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : R. G. McKinnell
Publisher : Springer Science & Business Media
ISBN 13 : 3540382674
Total Pages : 327 pages
Book Rating : 4.5/5 (43 download)
Download or read book Differentiation and Neoplasia written by R. G. McKinnell and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is no commonly accepted mechanism to explain differentiation of either normal or neoplastic cells. Despite this fact, the organizers of the 3 rd International Conference on Differentiation recognized that there is much emerging evidence which supports the view that both normal cells and many cancer cells share common differentiative processes. Accordingly, the organizers perceived that clinical scientists and developmental biologists would greatly benefit by together considering differentiation. In that way, developmental biologists would be apprised of recent insights in cancer cell biology and the physician scientist would be updated on events in developmental biology and both would gain new understanding of the cell biology of neoplasia. A specific example may reveal the potential value of developmental biologists interacting with cancer physicians. An example chosen at random suggests that probably any paper included in the symposium volume would serve the purpose. Dr. Stephen Subtelny reviewed recent studies by his laboratory concerning germ cell migration and replication in frog embryos. How might those results interest the cancer scientist? Dr. Subtelny showed that primordial germ cells of a fertile graft will reverse their migratory direction and move into a sterile host. Perhaps in this context it would not be inappropriate to state that the germ cells of the graft metastasized into the host. Germ cells from grafts of a different species will populate the previously sterile host gonad.
Author : Rafal P. Piprek
Publisher : Springer
ISBN 13 : 3319319736
Total Pages : 444 pages
Book Rating : 4.3/5 (193 download)
Download or read book Molecular Mechanisms of Cell Differentiation in Gonad Development written by Rafal P. Piprek and published by Springer. This book was released on 2016-06-14 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
Author : W. J. Gehring
Publisher : Springer Science & Business Media
ISBN 13 : 354035803X
Total Pages : 323 pages
Book Rating : 4.5/5 (43 download)
Download or read book Genetic Mosaics and Cell Differentiation written by W. J. Gehring and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The relationship of cell lineage and differentiation is one of the most intriguing problems in developmental biology. In most higher organisms, the analysis of the cell lineage has to rely on indirect methods. Only in the most suitable systems, like the nematodes, can the pattern of cell division be determined by direct observation under the microscope. In cases where this is not possible, the fate of the cells has to be examined by using cell markers. Most suitable for this purpose are genetic markers, provided that they do not interfere with the developmental pathway to be studied. However, suitable genetic markers and techniques for generating genetic mosaics are available in a few organisms only. Therefore, this volume is largely concerned with Drosophila and the mouse, which have been studied most extensively. In 1929 STURTEVANT introduced the analysis of gynandromorphs into devel opmental genetics. However, this important contribution remained largely unnoticed until the late sixties, when the potential of this technique for deter mining embryonic fate maps and the number of primordial cells was exploited, and the methodology extended to the mapping of mutational foci. Mitotic recombination was demostrated by STER:-
Author : J. M. Ashworth
Publisher : Springer Science & Business Media
ISBN 13 : 9400957130
Total Pages : 64 pages
Book Rating : 4.4/5 (9 download)
Download or read book Cell Differentiation written by J. M. Ashworth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of an embryo is one of the which prevents entry of other sperm, fusion of most awe inspiring biological phenomena and the two haploid nuclei occurs and within about the study of cell differentiation can be traced 30 minutes the pigmented cortex rotates with respect to the underlying cytoplasm and in so back in antiquity to Aristotle and beyond However, there are few modern sciences which doing it reveals a grey, crescent shaped area on pay more than a cursory obeisance to their the side of the egg opposite to the point of founders and few students seem very interested entry of the sperm. This is another example of in the theories of their dead predecessors. polarity developing. Soon after fertilization the Embryology, though, is that rare exception - a zygote enters a period of rapid nuclear and cell division. The result of this cleavage process is science where the problems, theories and often that the egg cytoplasm is partitioned between techniques that excite our interest today, are essentially the same as those which excited our numerous cells whose ratio of nuclear volume to cytoplasmic volume is more like that found colleagues of fifty or even a hundred years ago. in an 'average' somatic cell.
Author : Jakob Reinert
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (75 download)
Download or read book Cell Cycle and Cell Differentiation written by Jakob Reinert and published by . This book was released on 1975 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. Reinert
Publisher : Springer Science & Business Media
ISBN 13 : 9783540070696
Total Pages : 331 pages
Book Rating : 4.0/5 (76 download)
Download or read book Cell Cycle and Cell Differentiation written by J. Reinert and published by Springer Science & Business Media. This book was released on 1975 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jean-Pierre Tassan
Publisher : Springer
ISBN 13 : 3319531506
Total Pages : 421 pages
Book Rating : 4.3/5 (195 download)
Download or read book Asymmetric Cell Division in Development, Differentiation and Cancer written by Jean-Pierre Tassan and published by Springer. This book was released on 2017-04-12 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer. To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological and pathological conditions. The book also illustrates the importance of this process for evolution and our need to understand the background mechanisms, offering a valuable guide not only for students in the field of developmental biology but also for experienced researchers from neighboring fields.
Author : Hitoshi Saitama
Publisher : Nova Publishers
ISBN 13 : 9781600219375
Total Pages : 324 pages
Book Rating : 4.2/5 (193 download)
Download or read book New Cell Differentiation Research Topics written by Hitoshi Saitama and published by Nova Publishers. This book was released on 2007 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book presents research developments from around the globe in the field of cellular differentiation which is a concept from developmental biology describing the process by which cells acquire a 'type'. The morphology of a cell may change dramatically during differentiation, but the genetic material remains the same, with few exceptions. A cell that is able to differentiate into many cell types is known as pluripotent. These cells are called stem cells in animals and meristematic cells in higher plants. A cell that is able to differentiate into all cell types is known as totipotent. In mammals, only the zygote and early embryonic cells are totipotent, while in plants, many differentiated cells can become totipotent with simple laboratory techniques.
Author : Lutz Nover
Publisher : Springer
ISBN 13 :
Total Pages : 658 pages
Book Rating : 4.X/5 ( download)
Download or read book Cell Differentiation written by Lutz Nover and published by Springer. This book was released on 1982-02 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three years have elapsed since the publication of the first edition of this book (in German). The continued interest of our readers and the rapid progress of our knowl edge in many fields necessitates a thoroughly revised and somewhat enlarged new edition. Cell differentiation is a prerequisite of life. It is defined as the prooess leading to the qualitatively and quantitatively selective realization of distinct parts of a given genetic material. Cell differentiation comprises five main aspects: (1) signal reception and transformation, (2) selective rearrangements of the genetic material, (3) differen tial gene expression, (4) organization of gene expression programs and (5) intercellular coordination of cell differentiation within the developmental programs of multicellular organisms. Despite the bewildering multiplicity of its results, i.e., the differentiated phenotypes of cells, there are apparently fundamental similarities with respect to the molecular mechanisms of the process itself. These mechanisms constitute the central subject of this book.
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309170427
Total Pages : 112 pages
Book Rating : 4.3/5 (91 download)
Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
Author : Robert B. Denman
Publisher :
ISBN 13 :
Total Pages : 383 pages
Book Rating : 4.:/5 (99 download)
Download or read book Results and Problems in Cell Differentiation, Volume 54 written by Robert B. Denman and published by . This book was released on 2011 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title contains: Introduction; Probing Astrocyte Function in Fragile X Syndrome; Neural Stem Cells; Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System; The Role of the Postsynaptic Density in the Pathology of the Fragile X Syndrome; Behavior in a Drosophila model of Fragile X; Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome; Fragile X Mental Retardation Protein and Stem Cells; and, Manipulating the Fragile X Mental Retardation Proteins in the Frog. This title also contains: Exploring the Zebra finch Taeniopygia gutta as a Novel Animal Mod.
Author : Lilianna Solnica-Krezel
Publisher : Springer
ISBN 13 : 9783642536670
Total Pages : 438 pages
Book Rating : 4.5/5 (366 download)
Download or read book Pattern Formation in Zebrafish written by Lilianna Solnica-Krezel and published by Springer. This book was released on 2012-11-28 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by leading experts in the field, this book provides the first comprehensive overview of the mechanisms of early patterning and morphogenesis in zebrafish. It summarizes the current knowledge and the key questions for the next decade of research.
Author : W. Hennig
Publisher : Springer Science & Business Media
ISBN 13 : 3540398384
Total Pages : 206 pages
Book Rating : 4.5/5 (43 download)
Download or read book Germ Line — Soma Differentiation written by W. Hennig and published by Springer Science & Business Media. This book was released on 2013-06-05 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the oldest problems in developmental biology is the differentiation between germ line and somatic cells. The continuity of germ line cells between subsequent generations of multicellular organisms was first suggested by Owen, and later elaborated by A. Weismann to his famous germ line theory. His additional assumption that cellular differentiation was based on a differential representation of the genetic material in somatic cells was soon disproved. In some, apparently exceptional, cases, however, such differences in the genetic material between germ line and somatic cells were discovered. The best-known example is the nematod Ascaris. Boveri discovered and studied the fundamental differences in the karyotypes of germ line and soma of Parascaris equorum. Later, similar situations were found in some other organisms. However, in particular the work ofSpemann demonstrated that cellular differentiation in general is not accompanied by fundamental changes of the genetic material. Subsequently, the relatively few examples of germ line-soma differences achieved by chromatin elimination processes have been considered as a curiosity. Experimental studies have been essentially restricted to Ascaris species and to the pioneering cytological studies of chromatin elimination by S. Beermann. Despite the large proportions of the genome involved in chromatin elimina tion, our knowledge of this process is still very restricted. In particular the biological meaning of this differentiation process is entirely obscure. In this context one must, however, consider that also for the majority of DNA sequences in eukaryotic genomes the biological relevance is unclear.
