The Chemistry and Biology of Nitroxyl (HNO)

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Author :
Publisher : Elsevier
ISBN 13 : 0128011645
Total Pages : 425 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Chemistry and Biology of Nitroxyl (HNO) by : Fabio Doctorovich

Download or read book The Chemistry and Biology of Nitroxyl (HNO) written by Fabio Doctorovich and published by Elsevier. This book was released on 2016-09-01 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule's structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound's foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. - Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research - Provides a valuable coverage of HNO's chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule - Contains high quality content from recognized experts in both industry and academia

Protective and Detrimental Role of Heme Oxygenase-1

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Author :
Publisher : MDPI
ISBN 13 : 3039218069
Total Pages : 220 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Protective and Detrimental Role of Heme Oxygenase-1 by : Valeria Sorrenti

Download or read book Protective and Detrimental Role of Heme Oxygenase-1 written by Valeria Sorrenti and published by MDPI. This book was released on 2019-11-14 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book “Protective and Detrimental Role of Heme Oxygenase-1”, includes a selection of original research papers and reviews aimed at understanding the dual role (protective and detrimental) of HO-1 and the involved signaling pathways. Original research papers and reviews aimed at the identification of natural molecules or new synthetic compounds able to modulate HO-1 activity/expression help make HO-1 a potential therapeutic target for the amelioration of various diseases.

Redox Biochemistry

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Publisher : John Wiley & Sons
ISBN 13 : 9780470177327
Total Pages : 350 pages
Book Rating : 4.1/5 (773 download)

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Book Synopsis Redox Biochemistry by : Ruma Banerjee

Download or read book Redox Biochemistry written by Ruma Banerjee and published by John Wiley & Sons. This book was released on 2007-12-04 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the premier, single-source reference on redox biochemistry, a rapidly emerging field. This reference presents the basic principles and includes detailed chapters focusing on various aspects of five primary areas of redox biochemistry: antioxidant molecules and redox cofactors; antioxidant enzymes; redox regulation of physiological processes; pathological processes related to redox; and specialized methods. This is a go-to resource for professionals in pharmaceuticals, medicine, immunology, nutrition, and environmental fields and an excellent text for upper-level students.

Recent Trends in Radiation Chemistry

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Publisher : World Scientific
ISBN 13 : 9814282073
Total Pages : 634 pages
Book Rating : 4.8/5 (142 download)

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Book Synopsis Recent Trends in Radiation Chemistry by : James F. Wishart

Download or read book Recent Trends in Radiation Chemistry written by James F. Wishart and published by World Scientific. This book was released on 2010 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a review of the trends in the field of radiation chemistry research. It covers a broad spectrum of topics, ranging from the historical perspective, instrumentation of accelerators in the nanosecond to femtosecond region, through the use ofradiation chemical methods in the study of antioxidants and nanomaterials, radiation-induced DNA damage by ionizing radiation involving both direct and indirect effects, to ultrafast events in free electron transfer, radiation-induced processes at solid-liquid interfaces and the recent work on infrared spectroscopy and radiation chemistry. The book is unique in that it covers a wide spectrum of topics that will be of great interest to beginners as well as experts. Recent data on ultrafast phenomena from the recently established world-class laser-driven accelerators facilities in the US, France and Japan are reviewed.

Nitric Oxide

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Publisher : Academic Press
ISBN 13 : 0080525032
Total Pages : 1023 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Nitric Oxide by : Louis J. Ignarro

Download or read book Nitric Oxide written by Louis J. Ignarro and published by Academic Press. This book was released on 2000-09-13 with total page 1023 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. - Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide - Authored by world experts on nitric oxide - Includes an overview of basic principles of biology and chemical biology - Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense

Nitric Oxide

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Author :
Publisher : Academic Press
ISBN 13 : 0128004398
Total Pages : 483 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Nitric Oxide by :

Download or read book Nitric Oxide written by and published by Academic Press. This book was released on 2014-08-12 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on nitric oxide. - Expertise of the contributors - Coverage of a vast array of subjects - In depth current information at the molecular to the clinical levels - Three-dimensional structures in color - Elaborate signaling pathways

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Nitric Oxide Donors

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Publisher : Academic Press
ISBN 13 : 0128134593
Total Pages : 367 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nitric Oxide Donors by : Amedea Seabra

Download or read book Nitric Oxide Donors written by Amedea Seabra and published by Academic Press. This book was released on 2017-03-17 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications. This book encompasses several topics on nitric oxide such as its sources and biological properties; its performance in the cardiovascular and neurologic systems, in the human skin and its application in the treatment of neglected diseases, neurodegenerative disorders, and cancer. Additionally, it covers its role in inflammation and immunity, penile erection function, photodynamic therapy, antimicrobial activities. It also discusses the future of nitric oxide donors in combination with other therapeutic drugs, in implantable sensors, and nitric oxide releasing hydrogels and medical devices for topical applications. The book is a valuable source for researchers on different areas of biomedical field who are interested in the improvements that these molecules can make in the treatment of several conditions. - Provides background information about biology and chemistry of nitric oxide - Discusses the state-of-the-art in the design of nitric oxide releasing nanomaterials for biomedical applications - Covers the usage of nitric oxide donors in the treatment of several conditions, such as cancer, human skin, cardiovascular system, and immunity - Discusses the future of nitric oxide donors and their FDA approval

Recent Advances in Microbial Oxygen-Binding Proteins

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Publisher : Academic Press
ISBN 13 : 0128033320
Total Pages : 384 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Recent Advances in Microbial Oxygen-Binding Proteins by :

Download or read book Recent Advances in Microbial Oxygen-Binding Proteins written by and published by Academic Press. This book was released on 2015-11-26 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This latest volume in Advances in Microbial Physiology continues the long tradition of topical and important reviews in microbiology. - Contains contributions from leading authorities in the field of microbial physiology - Informs and updates on all the latest developments in the field

Nitric Oxide Action in Abiotic Stress Responses in Plants

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Author :
Publisher : Springer
ISBN 13 : 3319178040
Total Pages : 252 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Nitric Oxide Action in Abiotic Stress Responses in Plants by : M. Nasir Khan

Download or read book Nitric Oxide Action in Abiotic Stress Responses in Plants written by M. Nasir Khan and published by Springer. This book was released on 2015-04-20 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an up-to-date review of the regulatory role of nitric oxide (NO) changes in the morphological, physio-biochemical as well as molecular characteristics of plants under abiotic stress. The first of two parts comprises four chapters and focuses on the properties, chemical reactions involving NO and reactive nitrogen species in plants. The second part, consisting of eleven chapters, describes the current understanding of the role of NO in the regulation of gene expression, NO signaling pathways and its role in the up-regulation of the endogenous defense system and programmed cell death. Furthermore, its interactions with other signaling molecules and plant hemoglobins under environmental and soil related abiotic stresses, including post-harvest stress in fruits, vegetables and ornamentals and wounding are discussed in detail. Together with the companion book Nitric Oxide in Plants: Metabolism and Role in Stress Physiology, this volume provides a concise overview of the field and offers a valuable reference work for teachers and researchers in the fields of plant physiology, biochemistry and agronomy.

Nitrite and Nitrate in Human Health and Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 1607616165
Total Pages : 318 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Nitrite and Nitrate in Human Health and Disease by : AnnMarie Kocher

Download or read book Nitrite and Nitrate in Human Health and Disease written by AnnMarie Kocher and published by Springer Science & Business Media. This book was released on 2011-04-15 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitrite and Nitrate in Human Health and Disease delivers a comprehensive review of nitrite and nitrate biology, from basic biochemistry to the complex physiology and metabolism of these two naturally occurring molecules in the human body. Well-organized and well referenced chapters cover the rich history of nitrite and nitrate, sources of exposure, and the physiological effects when consumed through foods containing nitrite and nitrate. The chapters are written by leading experts, all of whom share their research and perspectives in order to help define the context for benefits vs. any potential risks associated with nitrite and nitrate use, either through dietary ingestion or therapeutic dosing. This diverse collection of authors includes vascular biologists, physiologists, physicians, epidemiologists, cancer biologists, registered dieticians, chemists, and public health experts from five countries in both academia and government. Nitrite and Nitrate in Human Health and Disease provides a balanced view of nitric oxide biochemistry, and nitrite and nitrate biochemistry in physiology and in the food sciences.

WHO Guidelines for Indoor Air Quality

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Publisher : World Health Organization
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis WHO Guidelines for Indoor Air Quality by :

Download or read book WHO Guidelines for Indoor Air Quality written by and published by World Health Organization. This book was released on 2010 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.

Recent Trends in Medicinal Plants Research

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Publisher : Academic Press
ISBN 13 : 0123947995
Total Pages : 475 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Recent Trends in Medicinal Plants Research by :

Download or read book Recent Trends in Medicinal Plants Research written by and published by Academic Press. This book was released on 2012-11-13 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants and other living organisms have great potential to treat human disease. There are two distinct types of biomedical research that seek to develop this potential. One type of research explores the value of medicinal plants as traditionally used and studies of these plants have the potential to determine which plants are most potent, optimize dosages and dose forms, and identify safety risks. Another type of research uses bioassays to identify single molecules from plants that have interesting bioactivities in isolation and might be useful lead compounds for the development of pharmaceutical drugs. This new volume of Advances in Botanical Research covers the recent trends in Medicinal Plants Research over 11 chapters. Topics that are covered include Development of Drugs from Plants – Regulation and Evaluation, Chinese Herbal Medicines for Rheumatoid Arthritis, and Taxol, camptothecin and beyond for cancer therapy. - Covers the recent trends in medicinal plants research over 11 chapters - Topics that are covered include Development of Drugs from Plants – Regulation and Evaluation, Chinese Herbal Medicines for Rheumatoid Arthritis, and Taxol, camptothecin and beyond for cancer therapy

Organic Nitrates

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Publisher : Springer Science & Business Media
ISBN 13 : 364266024X
Total Pages : 206 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Organic Nitrates by : P. Needleman

Download or read book Organic Nitrates written by P. Needleman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little was known concerning what these drugs do to the body or what the body does to the drugs. A substantial number of investigators have focused on these questions especially during the last two decades. We now have considerably more insight into the pathways of degradation of organic nitrates and the relationship of the metabolic processes to the biological action of these agents. Similarly, considerable effort has been expended in understanding the mechanism of action of these agents directly on vascular smooth muscle and on cardiac work and performance. Finally, there is a more substantive understanding of the physiology of the coronary circulation as well as the" pathophysiologic manifestations of myocardial disease.

Nitric Oxide and Signaling in Plants

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Author :
Publisher : Academic Press
ISBN 13 : 0128013206
Total Pages : 402 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Nitric Oxide and Signaling in Plants by :

Download or read book Nitric Oxide and Signaling in Plants written by and published by Academic Press. This book was released on 2016-02-25 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Currently in its 77th volume, the series features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. - Publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences - Contains commentary by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology, and ecology

Annual Plant Reviews, Nitrogen Metabolism in Plants in the Post-genomic Era

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Publisher : John Wiley & Sons
ISBN 13 : 1444347659
Total Pages : 326 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Annual Plant Reviews, Nitrogen Metabolism in Plants in the Post-genomic Era by : Christine Foyer

Download or read book Annual Plant Reviews, Nitrogen Metabolism in Plants in the Post-genomic Era written by Christine Foyer and published by John Wiley & Sons. This book was released on 2011-06-09 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of plant nitrogen metabolism continues to be a compelling focus for basic research activities because there is a strong demand for immediate solutions, particularly in key areas, such as improving plant nitrogen use efficiency, which are crucial to future agricultural sustainability and the future economic success of agriculture. The 13 reviews which comprise this excellent and carefully edited new volume bring together the expertise and enthusiasm of an international team of leading researchers. Topics covered include nitrogen sensing and signalling, uptake and membrane systems, nitric oxide, primary nitrogen assimilation and C/N balance and interactions, and regulation of root and plant architecture. Together, these reviews provide an insight into how plants sense, uptake and assimilate nitrogen into the organic compounds required for growth, co-ordinate nitrogen and carbon metabolism and regulate growth and development according to nitrogen availability. The transcription factors that act to integrate environmental nutrient (nitrogen) signals to co-ordinate primary and secondary metabolism are discussed, together with new concepts of cross-talk, transport and signalling, and how such molecular networks influence nitrogen and carbon cycling processes in the environment. Annual Plant Reviews, Volume 42: Nitrogen Metabolism in Plants in the Post-genomic Era is an essential purchase for advanced students, researchers and professionals in plant sciences, biochemistry, physiology, molecular biology, genetics and agricultural sciences, working in the academic and industrial sectors. Libraries in all universities and research establishments where these subjects are studied and taught will need copies of this excellent volume on their shelves.

Advances in Microbial Physiology

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Publisher : Academic Press
ISBN 13 : 0323850871
Total Pages : 404 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Advances in Microbial Physiology by : Robert K. Poole

Download or read book Advances in Microbial Physiology written by Robert K. Poole and published by Academic Press. This book was released on 2021-06-17 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Microbial Physiology, Volume 78, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. This updated release contains the latest information in the field, with comprehensive chapters covering Microbubble Intensification of Bioprocessing, Bacterial cellulose: biosynthesis, production, and applications, Microbial energy management – a product of three broad tradeoffs, and more. - Contains contributions from leading authorities in microbial physiology - Informs and updates on all the latest developments in the field of microbial physiology