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Author : Eiro Tsubura
Publisher :
ISBN 13 : 9784900392540
Total Pages : 0 pages
Book Rating : 4.3/5 (925 download)
Download or read book Rationale of Biological Response Modifiers in Cancer Treatment written by Eiro Tsubura and published by . This book was released on 1985 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Liro Tsubura
Publisher :
ISBN 13 :
Total Pages : 267 pages
Book Rating : 4.:/5 (658 download)
Download or read book Rationale of Biological Response Modifiers in Cancer Treatment written by Liro Tsubura and published by . This book was released on 1985 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : James E. Talmadge
Publisher : Springer Science & Business Media
ISBN 13 : 1461325919
Total Pages : 205 pages
Book Rating : 4.4/5 (613 download)
Download or read book Screening for Biological Response Modifiers: Methods and Rationale written by James E. Talmadge and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The observation in the 1950s that nitrogen mustard and other toxic chemicals could induce antitumor responses in patients with refractory lymphoma initiated a massive search for active chemotherapeutic agents. The initial observations stimulated a search for new chemotherapeutic agents which might have increased antitumor activity with less toxicity for normal tissues. To aid in the search for these new chemicals and to attempt to distinguish among the many toxic chemicals which might be candidates for clinical studies, the National Cancer Institute, the pharmaceutical industry, and the cancer research laboratories of most Western nations developed systems for "screening" drugs for antitumor activity. Perhaps the most extensive screening program was established by the National Cancer Institute (1). This screening program has evolved over the last two decades, an evolution which has been repeatedly reviewed (2-5). Various screening programs in use have examined over 500,000 compounds as potential anticancer agents. From these, there are now approximately forty anticancer drugs in clinical use. The utiliy of these compounds and their toxicities have been reviewed on many occasions. It is now apparent that more active and less toxic anticancer drugs are needed. It is also clear that the current screening programs are identifying compounds with similar levels of activity and with continuing moderate to severe toxicity (6).
Author : Institute for Advanced Studies in Immunology & Aging
Publisher : Plenum Publishing Corporation
ISBN 13 : 9780306445897
Total Pages : 0 pages
Book Rating : 4.4/5 (458 download)
Download or read book Combination Therapies 2 written by Institute for Advanced Studies in Immunology & Aging and published by Plenum Publishing Corporation. This book was released on 1993 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the 2nd International Symposium on Combination Therapies for Cancer held in Sicily (Italy) in May 1992. Papers address the mechanism of action and rationale for use of biological response modifiers (BRM) in the treatment of cancer. BRM's possible role in treating infectious diseases,
Author : National Cancer Institute (U.S.) Subcommittee on Biological Response Modifiers
Publisher :
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.3/5 (121 download)
Download or read book Biological Response Modifiers written by National Cancer Institute (U.S.) Subcommittee on Biological Response Modifiers and published by . This book was released on 1983 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. W. Chiao
Publisher : Marcel Dekker
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.:/5 (45 download)
Download or read book Biological Response Modifiers and Cancer Therapy written by J. W. Chiao and published by Marcel Dekker. This book was released on 1988 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : W.E.G. Müller
Publisher : Springer Science & Business Media
ISBN 13 : 3642785492
Total Pages : 290 pages
Book Rating : 4.6/5 (427 download)
Download or read book Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates written by W.E.G. Müller and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological response modifiers are increasingly used in viral and cancer therapy. Since alterations of the immune system are the primary symptoms of HIV infection, especially therapies directed towards the modulation of the immune response have been under intense evaluation. This volume summarizes current knowledge of the interferon-based natural antiviral protection system including 2',5'-oligoadenylate and double-stranded RNA. It will also help to develop further a solid scientific rationale for the practical use of heterologous immunomodulators in the clinics.
Author : E. Garaci
Publisher : Springer Science & Business Media
ISBN 13 : 1461533406
Total Pages : 313 pages
Book Rating : 4.4/5 (615 download)
Download or read book Combination Therapies written by E. Garaci and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade many of the key lymphokines, hormones and growth factors that help regulate the immune system have been defined. These molecules, termed biological response modifiers (BRMs) , have been sequenced, synthesized and produced in large enough quantities to test in animals and humans resulting in the development of new approaches to the treatment of human disease, in particular, cancers and infectious diseases. Advances in this area have also led to rethinking therapies against a range of autoimmune disorders and other diseases associated with immune and endocrine imbalances. BRMs currently are being applied clinically as both primary and adjunctive therapy to enhance the effectiveness of traditional treatments by maximizing their activities and to protect critical tissues against intolerable chemotherapeutic and radiation damage. Present constraints against the use of BRMs revolve around the nature of these substances in vivo, where many of their actions and the majority of their interactions and synergies remain to be elucidated. For example, as these molecules are thought to exert their effects locally, the systemic administration of lymphokines, cytokines and growth factors at doses adequate to produce a wanted anti-tumor effect in many instances is intolerably toxic. Efforts to overcome this formidable problem have led scientists to begin to explore the transfer of genes known to encode for these molecules into cells which otherwise inadequately elicit or produce anti-tumor or anti-infective responses.
Author : Herbert Michael Pinedo
Publisher :
ISBN 13 : 9780444904850
Total Pages : 592 pages
Book Rating : 4.9/5 (48 download)
Download or read book Cancer Chemotherapy and Biological Response Modifiers Annual written by Herbert Michael Pinedo and published by . This book was released on 1987 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its ninth year the Cancer Chemotherapy Annual series has been renamed, reformatted and expanded to include a section on biological response modifiers. It is, and will remain, the only medium for oncologists to keep pace with the many thousands of articles published in their field. The international board of some seventy contributors now also includes experts in biological therapeutics, who have evaluated their segment of the international medical literature. The editors, H.M. Pinedo and B.A. Chabner, have secured the assistance of D.L. Longo, who qualifies as the director of the Biological Response Modifiers Program of the National Cancer Institute in Frederick, MD, USA.
Author : Bruce A. Chabner
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451148208
Total Pages : 836 pages
Book Rating : 4.4/5 (511 download)
Download or read book Cancer Chemotherapy and Biotherapy written by Bruce A. Chabner and published by Lippincott Williams & Wilkins. This book was released on 2011-12-07 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated to include the newest drugs and those currently in development, this Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised. A companion website includes the fully searchable text and an image bank.
Author : Malcolm S. Mitchell
Publisher : McGraw-Hill Professional Publishing
ISBN 13 :
Total Pages : 618 pages
Book Rating : 4.3/5 (91 download)
Download or read book Biological Approaches to Cancer Treatment written by Malcolm S. Mitchell and published by McGraw-Hill Professional Publishing. This book was released on 1993 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique monograph reviews the biological principles of cancer immunotherapy & focuses specifically on biomodulation-the use of any substance to augment the host's antitumor response. Coverage begins with a detailed overview of the immunological basis on which biological therapy is grounded. Here, interactions among elements of the immune response are stressed throughout. Next, the text focuses on treatment including various forms of immunotherapy & future directions of cancer therapy in this rapidly expanding area.
Author : H. M. Pinedo
Publisher : Elsevier Science & Technology
ISBN 13 : 9780444815095
Total Pages : 698 pages
Book Rating : 4.8/5 (15 download)
Download or read book Cancer Chemotherapy and Biological Response Modifiers written by H. M. Pinedo and published by Elsevier Science & Technology. This book was released on 1993-01-01 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the recent major advances that have been made in the understanding of cancer biology, which have resulted in the development of both new classes of anti-cancer agents and new approaches to cancer treatment.
Author :
Publisher :
ISBN 13 :
Total Pages : 16 pages
Book Rating : 4.:/5 (319 download)
Download or read book Biological Response Modifiers written by and published by . This book was released on 1984 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Eiro Tsubura
Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.3/5 (91 download)
Download or read book Rationale of Biological Response Modifiers in Cancer Treatment written by Eiro Tsubura and published by Elsevier Science & Technology. This book was released on 1985 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paul F. Torrence
Publisher :
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.:/5 (44 download)
Download or read book Biological Response Modifiers written by Paul F. Torrence and published by . This book was released on 1985 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Herbert M. Pinedo
Publisher :
ISBN 13 : 9780444810151
Total Pages : 614 pages
Book Rating : 4.8/5 (11 download)
Download or read book Cancer Chemotherapy and Biological Response Modifiers written by Herbert M. Pinedo and published by . This book was released on 1988 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Andor Szentivanyi, PhD
Publisher : Springer
ISBN 13 : 9781475714111
Total Pages : 336 pages
Book Rating : 4.7/5 (141 download)
Download or read book Biological Response Modifiers in Human Oncology and Immunology written by Andor Szentivanyi, PhD and published by Springer. This book was released on 2014-01-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
