Rapid Medical Countermeasure Response To Infectious Diseases

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Rapid Medical Countermeasure Response to Infectious Diseases

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309378648
Total Pages : 177 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Rapid Medical Countermeasure Response to Infectious Diseases by : National Academies of Sciences, Engineering, and Medicine

Download or read book Rapid Medical Countermeasure Response to Infectious Diseases written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-02-12 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging infectious disease threats that may not have available treatments or vaccines can directly affect the security of the world's health since these diseases also know no boundaries and will easily cross borders. Sustaining public and private investment in the development of medical countermeasures (MCMs) before an emerging infectious disease becomes a public health emergency in the United States has been extremely challenging. Interest and momentum peak during a crisis and wane between events, and there is little interest in disease threats outside the United States until they impact people stateside. On March 26 and 27, 2015, the Institute of Medicine convened a workshop in Washington, DC to discuss how to achieve rapid and nimble MCM capability for new and emerging threats. Public- and private-sector stakeholders examined recent efforts to prepare for and respond to outbreaks of Ebola Virus Disease, pandemic influenza, and coronaviruses from policy, budget, and operational standpoints. Participants discussed the need for rapid access to MCM to ensure national security and considered strategies and business models that could enhance stakeholder interest and investment in sustainable response capabilities. This report summarizes the presentations and discussions from this workshop.

Building a National Capability to Monitor and Assess Medical Countermeasure Use During a Public Health Emergency

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309466423
Total Pages : 121 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Building a National Capability to Monitor and Assess Medical Countermeasure Use During a Public Health Emergency by : National Academies of Sciences, Engineering, and Medicine

Download or read book Building a National Capability to Monitor and Assess Medical Countermeasure Use During a Public Health Emergency written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-01-20 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: During public health emergencies (PHEs) involving chemical, biological, radiological, or nuclear threats or emerging infectious diseases, medical countermeasures (MCMs) (e.g., drugs, vaccines, devices) may need to be dispensed or administered to affected populations to help mitigate the human health impact of the threat. The optimal MCMs determined for use during an emergency might be U.S. Food and Drug Administration (FDA) approved but used in unapproved ways (e.g., in a new age group or against a new agent); FDA approved using animal models because human efficacy testing is not ethical or feasible; or not yet FDA approved for any indication. As part of the United States' scientific and research preparedness enterprise, there is an imperative to go "beyond the last mile" of MCM dispensing and administration to build and maintain a national capability to monitor and assess the use of MCMs (e.g., safety, compliance, clinical benefit) after they have been dispensed during PHEs. To further the discussion on this need, the Board on Health Sciences Policy of the National Academies of Sciences, Engineering, and Medicine hosted a 2-day public workshop, Building a National Capability to Monitor and Assess Medical Countermeasure Use in Response to Public Health Emergencies. The workshop, sponsored by FDA, was held on June 6â€"7, 2017, in Washington, DC. Workshop participants discussed the roles and efforts of the federal government and of relevant stakeholders with an interest in building and maintaining a national PHE MCM active monitoring and assessment capability. This publication summarizes the presentations and discussions from the workshop.

Medical Countermeasures Dispensing

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309186501
Total Pages : 95 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Countermeasures Dispensing by : Institute of Medicine

Download or read book Medical Countermeasures Dispensing written by Institute of Medicine and published by National Academies Press. This book was released on 2010-12-16 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: During public health emergencies such as terrorist attacks or influenza outbreaks, the public health system's ability to save lives could depend on dispensing medical countermeasures such as antibiotics, antiviral medications, and vaccines to a large number of people in a short amount of time. The IOM's Forum on Medical and Public Health Preparedness for Catastrophic Events held a workshop on November 18, 2009, to provide an overview of current threats, recent progress made in the public health system for distributing and dispensing countermeasures, and remaining vulnerabilities.

Global Health and the Future Role of the United States

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309457661
Total Pages : 385 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Global Health and the Future Role of the United States by : National Academies of Sciences, Engineering, and Medicine

Download or read book Global Health and the Future Role of the United States written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-05 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: While much progress has been made on achieving the Millenium Development Goals over the last decade, the number and complexity of global health challenges has persisted. Growing forces for globalization have increased the interconnectedness of the world and our interdependency on other countries, economies, and cultures. Monumental growth in international travel and trade have brought improved access to goods and services for many, but also carry ongoing and ever-present threats of zoonotic spillover and infectious disease outbreaks that threaten all. Global Health and the Future Role of the United States identifies global health priorities in light of current and emerging world threats. This report assesses the current global health landscape and how challenges, actions, and players have evolved over the last decade across a wide range of issues, and provides recommendations on how to increase responsiveness, coordination, and efficiency â€" both within the U.S. government and across the global health field.

Evidence-Based Practice for Public Health Emergency Preparedness and Response

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309670381
Total Pages : 501 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Evidence-Based Practice for Public Health Emergency Preparedness and Response by : National Academies of Sciences, Engineering, and Medicine

Download or read book Evidence-Based Practice for Public Health Emergency Preparedness and Response written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-11-28 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: When communities face complex public health emergencies, state local, tribal, and territorial public health agencies must make difficult decisions regarding how to effectively respond. The public health emergency preparedness and response (PHEPR) system, with its multifaceted mission to prevent, protect against, quickly respond to, and recover from public health emergencies, is inherently complex and encompasses policies, organizations, and programs. Since the events of September 11, 2001, the United States has invested billions of dollars and immeasurable amounts of human capital to develop and enhance public health emergency preparedness and infrastructure to respond to a wide range of public health threats, including infectious diseases, natural disasters, and chemical, biological, radiological, and nuclear events. Despite the investments in research and the growing body of empirical literature on a range of preparedness and response capabilities and functions, there has been no national-level, comprehensive review and grading of evidence for public health emergency preparedness and response practices comparable to those utilized in medicine and other public health fields. Evidence-Based Practice for Public Health Emergency Preparedness and Response reviews the state of the evidence on PHEPR practices and the improvements necessary to move the field forward and to strengthen the PHEPR system. This publication evaluates PHEPR evidence to understand the balance of benefits and harms of PHEPR practices, with a focus on four main areas of PHEPR: engagement with and training of community-based partners to improve the outcomes of at-risk populations after public health emergencies; activation of a public health emergency operations center; communication of public health alerts and guidance to technical audiences during a public health emergency; and implementation of quarantine to reduce the spread of contagious illness.

Emerging Viral Diseases

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309314003
Total Pages : 336 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Emerging Viral Diseases by : Institute of Medicine

Download or read book Emerging Viral Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2015-03-19 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past half century, deadly disease outbreaks caused by novel viruses of animal origin - Nipah virus in Malaysia, Hendra virus in Australia, Hantavirus in the United States, Ebola virus in Africa, along with HIV (human immunodeficiency virus), several influenza subtypes, and the SARS (sudden acute respiratory syndrome) and MERS (Middle East respiratory syndrome) coronaviruses - have underscored the urgency of understanding factors influencing viral disease emergence and spread. Emerging Viral Diseases is the summary of a public workshop hosted in March 2014 to examine factors driving the appearance, establishment, and spread of emerging, re-emerging and novel viral diseases; the global health and economic impacts of recently emerging and novel viral diseases in humans; and the scientific and policy approaches to improving domestic and international capacity to detect and respond to global outbreaks of infectious disease. This report is a record of the presentations and discussion of the event.

Global Health Risk Framework

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309381029
Total Pages : 141 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Global Health Risk Framework by : National Academies of Sciences, Engineering, and Medicine

Download or read book Global Health Risk Framework written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-05-06 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the 2014 Ebola outbreak many public- and private-sector leaders have seen a need for improved management of global public health emergencies. The effects of the Ebola epidemic go well beyond the three hardest-hit countries and beyond the health sector. Education, child protection, commerce, transportation, and human rights have all suffered. The consequences and lethality of Ebola have increased interest in coordinated global response to infectious threats, many of which could disrupt global health and commerce far more than the recent outbreak. In order to explore the potential for improving international management and response to outbreaks the National Academy of Medicine agreed to manage an international, independent, evidence-based, authoritative, multistakeholder expert commission. As part of this effort, the Institute of Medicine convened four workshops in summer of 2015 to inform the commission report. The presentations and discussions from the Workshop on Research and Development of Medical Products are summarized in this report.

Exploring Lessons Learned from a Century of Outbreaks

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309490359
Total Pages : 231 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Exploring Lessons Learned from a Century of Outbreaks by : National Academies of Sciences, Engineering, and Medicine

Download or read book Exploring Lessons Learned from a Century of Outbreaks written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-06-05 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: In November 2018, an ad hoc planning committee at the National Academies of Sciences, Engineering, and Medicine planned two sister workshops held in Washington, DC, to examine the lessons from influenza pandemics and other major outbreaks, understand the extent to which the lessons have been learned, and discuss how they could be applied further to ensure that countries are sufficiently ready for future pandemics. This publication summarizes the presentations and discussions from both workshops.

Prepositioning Antibiotics for Anthrax

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030921808X
Total Pages : 358 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Prepositioning Antibiotics for Anthrax by : Institute of Medicine

Download or read book Prepositioning Antibiotics for Anthrax written by Institute of Medicine and published by National Academies Press. This book was released on 2012-02-26 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: If terrorists released Bacillus anthracis over a large city, hundreds of thousands of people could be at risk of the deadly disease anthrax-caused by the B. anthracis spores-unless they had rapid access to antibiotic medical countermeasures (MCM). Although plans for rapidly delivering MCM to a large number of people following an anthrax attack have been greatly enhanced during the last decade, many public health authorities and policy experts fear that the nation's current systems and plans are insufficient to respond to the most challenging scenarios, such as a very large-scale anthrax attack. The U.S. Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response commissioned the Institute of Medicine to examine the potential uses, benefits, and disadvantages of strategies for repositioning antibiotics. This involves storing antibiotics close to or in the possession of the people who would need rapid access to them should an attack occur. Prepositioning Antibiotics for Anthrax reviews the scientific evidence on the time window in which antibiotics successfully prevent anthrax and the implications for decision making about prepositioning, describes potential prepositioning strategies, and develops a framework to assist state, local, and tribal public health authorities in determining whether prepositioning strategies would be beneficial for their communities. However, based on an analysis of the likely health benefits, health risks, and relative costs of the different prepositioning strategies, the book also develops findings and recommendations to provide jurisdictions with some practical insights as to the circumstances in which different prepositioning strategies may be beneficial. Finally, the book identifies federal- and national-level actions that would facilitate the evaluation and development of prepositioning strategies. Recognizing that communities across the nation have differing needs and capabilities, the findings presented in this report are intended to assist public health officials in considering the benefits, costs, and trade-offs involved in developing alternative prepositioning strategies appropriate to their particular communities.

The Nation's Medical Countermeasure Stockpile

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309443709
Total Pages : 143 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis The Nation's Medical Countermeasure Stockpile by : National Academies of Sciences, Engineering, and Medicine

Download or read book The Nation's Medical Countermeasure Stockpile written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-10-24 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Large catastrophic events, or rare acute events, may cause situations in which a local jurisdiction's medicines and medical supplies are not sufficient to provide care to the population it serves. In these cases of natural or engineered disasters, such as a terrorist attack, influenza pandemic, or earthquake, state or local authorities can request that the federal government provide assets from the Strategic National Stockpile to augment the state and local jurisdictions' resources. The Centers for Disease Control and Prevention's (CDC's) Strategic National Stockpile (SNS) is the nation's repository of antibiotics, chemical antidotes, antitoxins, vaccines, antiviral drugs, and other medical materiel designed to supplement and resupply state and local public health agencies in the event of an emergency. The materiel is intended to support national health security and is managed by the Office of Public Health Preparedness and Response's (OPHPR's) Division of Strategic National Stockpile (DSNS). The stated mission of the SNS is to prepare and support partners and provide the right resources at the right time to secure the nation's health. The National Academies of Sciences, Engineering, and Medicine organized a two-day public workshop to explore opportunities to improve the efficiency, effectiveness, and sustainable methods used by the CDC's SNS to distribute medical countermeasures and other supplies during disasters and other public health emergencies, especially those which result in disruption of physical infrastructure such as the electrical grid, central roadways, bridges, and tunnels within the impacted community. Participants explored relevant distribution lessons learned from other federal agency stockpiles and the private sector as well as opportunities to develop public-private collaborations in the purchase, warehousing, management, and distribution of medical countermeasures. This report summarizes the presentations and discussions from the workshop.

Biodefense in the Age of Synthetic Biology

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309465184
Total Pages : 189 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Biodefense in the Age of Synthetic Biology by : National Academies of Sciences, Engineering, and Medicine

Download or read book Biodefense in the Age of Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-05 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

National Strategy for the COVID-19 Response and Pandemic Preparedness

Author : Joseph R. Biden, Jr.
Publisher : Simon and Schuster
ISBN 13 : 1510767614
Total Pages : 329 pages
Book Rating : 4.5/5 (17 download)

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Book Synopsis National Strategy for the COVID-19 Response and Pandemic Preparedness by : Joseph R. Biden, Jr.

Download or read book National Strategy for the COVID-19 Response and Pandemic Preparedness written by Joseph R. Biden, Jr. and published by Simon and Schuster. This book was released on 2021-05-04 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ultimate guide for anyone wondering how President Joe Biden will respond to the COVID-19 pandemic—all his plans, goals, and executive orders in response to the coronavirus crisis. Shortly after being inaugurated as the 46th President of the United States, Joe Biden and his administration released this 200 page guide detailing his plans to respond to the coronavirus pandemic. The National Strategy for the COVID-19 Response and Pandemic Preparedness breaks down seven crucial goals of President Joe Biden's administration with regards to the coronavirus pandemic: 1. Restore trust with the American people. 2. Mount a safe, effective, and comprehensive vaccination campaign. 3. Mitigate spread through expanding masking, testing, data, treatments, health care workforce, and clear public health standards. 4. Immediately expand emergency relief and exercise the Defense Production Act. 5. Safely reopen schools, businesses, and travel while protecting workers. 6. Protect those most at risk and advance equity, including across racial, ethnic and rural/urban lines. 7. Restore U.S. leadership globally and build better preparedness for future threats. Each of these goals are explained and detailed in the book, with evidence about the current circumstances and how we got here, as well as plans and concrete steps to achieve each goal. Also included is the full text of the many Executive Orders that will be issued by President Biden to achieve each of these goals. The National Strategy for the COVID-19 Response and Pandemic Preparedness is required reading for anyone interested in or concerned about the COVID-19 pandemic and its effects on American society.

Microbial Threats to Health

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309185548
Total Pages : 397 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Microbial Threats to Health by : Institute of Medicine

Download or read book Microbial Threats to Health written by Institute of Medicine and published by National Academies Press. This book was released on 2003-08-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.

Assessment of COVID-19 Response in the Republic of Korea

Author : Asian Development Bank
Publisher : Asian Development Bank
ISBN 13 : 9292627929
Total Pages : 79 pages
Book Rating : 4.2/5 (926 download)

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Book Synopsis Assessment of COVID-19 Response in the Republic of Korea by : Asian Development Bank

Download or read book Assessment of COVID-19 Response in the Republic of Korea written by Asian Development Bank and published by Asian Development Bank. This book was released on 2021-04-01 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: The effective response of the Republic of Korea (ROK) to the coronavirus disease (COVID-19) pandemic has been recognized worldwide. This publication looks into the governance structures and economic and social responses that contributed to the success of the ROK in coping with COVID-19. It examines key areas of the government’s response efforts including testing, tracing, and treatment approaches as well as economic stimulation initiatives. The publication identifies important lessons and insights for other countries to deal with the pandemic and its societal aftershocks.

Neuraminidase Inhibitors for Treatment of Influenza A and B Infections

Author :
Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Neuraminidase Inhibitors for Treatment of Influenza A and B Infections by :

Download or read book Neuraminidase Inhibitors for Treatment of Influenza A and B Infections written by and published by . This book was released on 1999 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Framework for Equitable Allocation of COVID-19 Vaccine

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 030968224X
Total Pages : 273 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Framework for Equitable Allocation of COVID-19 Vaccine by : National Academies of Sciences, Engineering, and Medicine

Download or read book Framework for Equitable Allocation of COVID-19 Vaccine written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-11-30 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the coronavirus disease 2019 (COVID-19) pandemic and the societal disruption it has brought, national governments and the international community have invested billions of dollars and immense amounts of human resources to develop a safe and effective vaccine in an unprecedented time frame. Vaccination against this novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), offers the possibility of significantly reducing severe morbidity and mortality and transmission when deployed alongside other public health strategies and improved therapies. Health equity is intertwined with the impact of COVID-19 and there are certain populations that are at increased risk of severe illness or death from COVID-19. In the United States and worldwide, the pandemic is having a disproportionate impact on people who are already disadvantaged by virtue of their race and ethnicity, age, health status, residence, occupation, socioeconomic condition, or other contributing factors. Framework for Equitable Allocation of COVID-19 Vaccine offers an overarching framework for vaccine allocation to assist policy makers in the domestic and global health communities. Built on widely accepted foundational principles and recognizing the distinctive characteristics of COVID-19, this report's recommendations address the commitments needed to implement equitable allocation policies for COVID-19 vaccine.

Public Health Systems and Emerging Infections

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 9780309183772
Total Pages : 128 pages
Book Rating : 4.1/5 (837 download)

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Book Synopsis Public Health Systems and Emerging Infections by : Institute of Medicine

Download or read book Public Health Systems and Emerging Infections written by Institute of Medicine and published by National Academies Press. This book was released on 2000-06-08 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Forum on Emerging Infections was created in 1996 in response to a request from the Centers for Disease Control and Prevention and the National Institutes of Health. The goal of the forum is to provide structured opportunities for representatives from academia, industry, professional and interest groups, and government to examine and discuss scientific and policy issues that relate to research, prevention, detection, and management of emerging infectious diseases. A critical part of this mission has been the convening of a series of workshops. Public Health Systems and Emerging Infections summarizes the fourth in a series of five workshops. With a focus on our knowledge and understanding of the role of private and public health sectors in emerging infectious disease surveillance and response, the participants explored the effects of privatization of public health laboratories and the modernization of public health care. The issues discussed included epidemiological investigation, surveillance, communication, coordination, resource allocations, and economic support.