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Author : Francisco Ciruela
Publisher : Frontiers Media SA
ISBN 13 : 2889459470
Total Pages : 852 pages
Book Rating : 4.8/5 (894 download)
Download or read book Purinergic Pharmacology written by Francisco Ciruela and published by Frontiers Media SA. This book was released on 2019-08-16 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Francisco Ciruela
Publisher : Frontiers Media SA
ISBN 13 : 283252575X
Total Pages : 187 pages
Book Rating : 4.8/5 (325 download)
Download or read book Purinergic pharmacology, volume II written by Francisco Ciruela and published by Frontiers Media SA. This book was released on 2023-06-07 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yong Tang
Publisher : Frontiers Media SA
ISBN 13 : 2832543561
Total Pages : 139 pages
Book Rating : 4.8/5 (325 download)
Download or read book Purinergic Signalling in the Central Nervous System and its pharmacological importance in neurological and psychiatric illnesses. written by Yong Tang and published by Frontiers Media SA. This book was released on 2024-01-26 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic aims to honour the 80th birthday of Professor Peter Illes, who is a member of the European Academy of Sciences, the founder/first president of the German Purine Club, and Honorary President of the Chinese Purine Club. He established a worldwide co-operation network on purinergic signalling and is an internationally recognized leader in the field. We aim to collect research articles and reviews from friends, colleagues and co-operation partners of Dr. Illes to showcase, build on and develop research being achieved related to the physiological/pathophysiological roles of purines in the central nervous system (CNS). Adenosine Triphosphate (ATP) is an intracellular energy-storing molecule, but may also reach the extracellular space, where it participates in cell-to-cell signalling. For this purpose, ATP utilises a range of purinergic receptors activated either by ATP itself (P2X receptors; seven subtypes) or by ATP/ADP and UTP/UDP (P2Y receptors; 8 subtypes) and finally via its enzymatic degradation product, adenosine (P1/A receptors; 4 subtypes). Purine nucleotides and nucleosides together with the whole plethora of receptors and degrading enzymes constitute the purinome. This fascinating and extensive network exists both in the animal kingdom and in humans and is essential in regulating important physiological functions. Disturbances in the network can lead to a variety of illnesses clinically associated with both neurological or psychiatric traits. In recent years, hope has arisen that pharmacological chemistry together with various newly developed methods, will enable researchers to discover and design efficient drugs for treating these neurodegenerative and affective diseases.
Author : Maria P. Abracchio
Publisher : Springer Science & Business Media
ISBN 13 : 3662096048
Total Pages : 544 pages
Book Rating : 4.6/5 (62 download)
Download or read book Purinergic and Pyrimidinergic Signalling written by Maria P. Abracchio and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiological, pharmacological and molecular biological data generated over the past three decades have demonstrated the existence of two major families of extracellular receptors, the P1, a family of four G-protein coupled receptors and the P2, a family of at least 12 receptors responsive to purine (ATP, ADP) and pyrimidine (UTP) nucleotides through which adenosine and ATP can function as extracellular messengers. The present two-part volume represents an integrated compendium of invited chapters by leading researchers in the area focusing on advances in the understanding of purinergic and pyrimidinergic signaling systems, their role(s) in tissue function and pathophysiology and advances in developing potential new medications based on the modulation of P1 and P2 receptor signaling processes. The volumes will thus provide the reader with a topical, comprehensive and integrated overview of this important area.
Author : Kenneth A Jacobson
Publisher : Academic Press
ISBN 13 : 0123855268
Total Pages : 559 pages
Book Rating : 4.1/5 (238 download)
Download or read book Pharmacology of Purine and Pyrimidine Receptors written by Kenneth A Jacobson and published by Academic Press. This book was released on 2011-06 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. Authors are the leading authorities in their fields Subject matter is important for understanding tissue protection Subject matter is of intense interest for new drug development
Author : Ralph W. Straub
Publisher :
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)
Download or read book Cell Membrane Receptors for Drugs and Hormones written by Ralph W. Straub and published by . This book was released on 1978 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robson Faria
Publisher : BoD – Books on Demand
ISBN 13 : 1789845343
Total Pages : 112 pages
Book Rating : 4.7/5 (898 download)
Download or read book Receptors P1 and P2 as Targets for Drug Therapy in Humans written by Robson Faria and published by BoD – Books on Demand. This book was released on 2020-03-11 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiological conditions. Additionally, we describe the mechanisms of induction of pain and inflammation in different systems. Finally, the book discusses some of the main bioinformatics tools currently used to improve or discover new prototypes capable of selectively acting on these receptors with estimated parameters of satisfactory solubility and toxicity for possible commercial implementation.
Author : Kenneth A. Jacobson
Publisher : Wiley-Liss
ISBN 13 : 9780471140719
Total Pages : 0 pages
Book Rating : 4.1/5 (47 download)
Download or read book Purinergic Approaches in Experimental Therapeutics written by Kenneth A. Jacobson and published by Wiley-Liss. This book was released on 1997-07-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by Kenneth A. Jacobson and Michael F. Jarvis The roles of extracellular purines and pyrimidines in cellularhomeostasis and disease etiology have come to be understoodgradually over the past 40 years. However, due to the recentcloning and expression of receptors for ATP and adenosine, novelcompounds have been developed with unique therapeutic potential forthe treatment of thrombosis, stroke, epilepsy, chronic pain,immunological disorders, and cancer. As a result, the study ofadenosine- and ATP-mediated responses in cellular regulation isentering a phase of opportunity and development unmatched since thedays of serotonin receptor research in the 1970s. The only definitive book on the topic, Purinergic Approaches inExperimental Therapeutics covers all of the major therapeuticapplications of purinergic receptors and reflects the very latestdevelopments in this new area of therapeutic research. Twenty-eightchapters, authored by an international group of contributors whoare the leading authorities in the field, provide details onmolecular pharmacology; medicinal chemistry; and therapeuticimplications, including cardiology, metabolism, immunology,neurology, and cancer. Among the topics covered: * Purinergic Neurotransmission and Neuromodulation: A HistoricalPerspective * Adenosine Receptor Subtypes: New Insights from Cloning andFunctional Studies * Modulators of Adenosine Uptake, Release, and Inactivation * Cardiac Electrophysiology of Adenosine: Antiarrhythmic andProarrhythmic Actions * Purinergic Modulation of Gastrointestinal Function * The Role of Adenosine in Asthma * ATP in Brain Function * ATP in the Treatment of Cancer For researchers in pharmacology, physiology, molecular biology, andmedicinal chemistry, Purinergic Approaches in ExperimentalTherapeutics heralds an exciting new era in the understanding ofpurinergic neurotransmission and the development of noveltherapeutic modalities.
Author : Rosa Gomez-Villafuertes
Publisher : Frontiers Media SA
ISBN 13 : 2889639649
Total Pages : 126 pages
Book Rating : 4.8/5 (896 download)
Download or read book Emerging Mechanisms in Purinergic Signaling: from Cell Biology to Therapeutic Perspectives written by Rosa Gomez-Villafuertes and published by Frontiers Media SA. This book was released on 2020-08-27 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Francesco Caciagli
Publisher : Frontiers Media SA
ISBN 13 : 2889715701
Total Pages : 287 pages
Book Rating : 4.8/5 (897 download)
Download or read book Purinergic Signaling 2020: the State-of-The-Art Commented by the Members of the Italian Purine Club written by Francesco Caciagli and published by Frontiers Media SA. This book was released on 2021-10-29 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Maria P. Abracchio
Publisher : Springer Science & Business Media
ISBN 13 : 3642569218
Total Pages : 459 pages
Book Rating : 4.6/5 (425 download)
Download or read book Purinergic and Pyrimidinergic Signalling II written by Maria P. Abracchio and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiological, pharmacological and molecular biological data generated over the past three decades have demonstrated the existence of two major families of extracellular receptors, the P1, a family of four G-protein coupled receptors and the P2, a family of at least 12 receptors responsive to purine (ATP, ADP) and pyrimidine (UTP) nucleotides through which adenosine and ATP can function as extracellular messengers. The present two-part volume represents an integrated compendium of invited chapters by leading researchers in the area focusing on advances in the understanding of purinergic and pyrimidinergic signaling systems, their role(s) in tissue function and pathophysiology and advances in developing potential new medications based on the modulation of P1 and P2 receptor signaling processes. The volumes will thus provide the reader with a topical, comprehensive and integrated overview of this important area.
Author : James M. Ritter
Publisher : Elsevier Health Sciences
ISBN 13 : 0702074462
Total Pages : 808 pages
Book Rating : 4.7/5 (2 download)
Download or read book Rang & Dale's Pharmacology written by James M. Ritter and published by Elsevier Health Sciences. This book was released on 2018-11-04 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: World-renowned coverage of today’s pharmacology at your fingertips Keeps you up-to-date with new information in this fast-changing field, including significantly revised coverage of CNS drugs, cognitive enhancers, anti-infectives, biologicals/biopharmaceuticals, lifestyle drugs, and more. Includes access to unique features, including more than 100 brand new chapter-specific multiple-choice questions and 6 new cases for immediate self-assessment. Features a color-coded layout for faster navigation and cross-referencing. Clarifies complex concepts with Key Points boxes, Clinical Uses boxes and full-color illustrations throughout.
Author : Leslie Iversen
Publisher : Oxford University Press
ISBN 13 : 0195380533
Total Pages : 568 pages
Book Rating : 4.1/5 (953 download)
Download or read book Introduction to Neuropsychopharmacology written by Leslie Iversen and published by Oxford University Press. This book was released on 2009 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: The text ranges from drugs that affect the mood and behavior to hypnotics, narcotics, anticonvulsants, and analgesics, as well as a variety of drugs that affect the autonomic nervous system and psychoactive drugs used for non-medical reasons - nicotine, alcohol, opiates, psychostimulants and cannabis."--BOOK JACKET.
Author : Stefan Offermanns
Publisher : Springer Science & Business Media
ISBN 13 : 3540389164
Total Pages : 1515 pages
Book Rating : 4.5/5 (43 download)
Download or read book Encyclopedia of Molecular Pharmacology written by Stefan Offermanns and published by Springer Science & Business Media. This book was released on 2008-08-14 with total page 1515 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
Author : Joen-Rong Sheu
Publisher : MDPI
ISBN 13 : 3038975419
Total Pages : 153 pages
Book Rating : 4.0/5 (389 download)
Download or read book Molecular Pharmacology and Pathology of Strokes written by Joen-Rong Sheu and published by MDPI. This book was released on 2019-02-11 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Molecular Pharmacology and Pathology of Strokes" that was published in IJMS
Author :
Publisher : Academic Press
ISBN 13 : 0123855330
Total Pages : 558 pages
Book Rating : 4.1/5 (238 download)
Download or read book Pharmacology of Purine and Pyrimidine Receptors written by and published by Academic Press. This book was released on 2011-07-13 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. Authors are the leading authorities in their fields Subject matter is important for understanding tissue protection Subject matter is of intense interest for new drug development
Author : James M. Ritter
Publisher : Elsevier Health Sciences
ISBN 13 : 0323873987
Total Pages : 1001 pages
Book Rating : 4.3/5 (238 download)
Download or read book Rang & Dale's Pharmacology E-Book written by James M. Ritter and published by Elsevier Health Sciences. This book was released on 2023-05-13 with total page 1001 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rang and Dale’s Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing. Comprehensive information on drug mechanisms, basic physiology and biochemistry, and underlying pathophysiology of disease – suitable for students from many disciplines Clear figures to aid understanding, including data figures as well as mechanistic diagrams, Key points box summaries, clinical boxes and colour-coded chapters help to master difficult concepts Emphasis on therapeutic drugs to help apply theory to practice Over 150 questions and 12 clinical cases to test your knowledge New chapters on drugs and the eye and the pharmacological management of headache Revised information on biopharmaceuticals (including RNA drugs), antivirals (including Covid-19 therapies) as well as general principles of antimicrobial therapy. A completely revised and updated chapter on lifestyle drugs Recent advances in oxygen sensing and response to reduced oxygen tension Expanded chapters on dementia and analgesic drugs
