Pot, Atom, and Step Economy (PASE) Synthesis

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Author :
Publisher : Springer
ISBN 13 : 3030225968
Total Pages : 49 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Pot, Atom, and Step Economy (PASE) Synthesis by : Wei Zhang

Download or read book Pot, Atom, and Step Economy (PASE) Synthesis written by Wei Zhang and published by Springer. This book was released on 2019-08-01 with total page 49 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book emphasizes the atom economy aspect of multicomponent reactions. It describes how this methodology has been applied to several named reactions. Among the “twelve principles of green chemistry”, atom economy addresses ‘synthetic efficiency’. A multicomponent reaction can be defined as an energy, cost, and time efficient method for organic synthesis. Instead of making one or two bonds in a chemical transformation, multicomponent reactions generate several chemical bonds in a single operation. This book presents a series of detailed reaction mechanisms that beautifully illustrate this principle. Multicomponent reactions are widely applied to the preparation of complex and diverse molecular structures in academic and industrial research laboratories. As such, this book is targeted at researchers involved in green organic chemistry.

Green Techniques for Organic Synthesis and Medicinal Chemistry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119288584
Total Pages : 728 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Green Techniques for Organic Synthesis and Medicinal Chemistry by : Wei Zhang

Download or read book Green Techniques for Organic Synthesis and Medicinal Chemistry written by Wei Zhang and published by John Wiley & Sons. This book was released on 2018-01-18 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.

Efficiency in Natural Product Total Synthesis

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118605403
Total Pages : 512 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Efficiency in Natural Product Total Synthesis by : Pei-Qiang Huang

Download or read book Efficiency in Natural Product Total Synthesis written by Pei-Qiang Huang and published by John Wiley & Sons. This book was released on 2018-10-16 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals

Multicomponent Reactions towards Heterocycles

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527349081
Total Pages : 626 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Multicomponent Reactions towards Heterocycles by : Erik Van der Eycken

Download or read book Multicomponent Reactions towards Heterocycles written by Erik Van der Eycken and published by John Wiley & Sons. This book was released on 2022-03-21 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a wide-ranging overview of essential topics and recent advances in MCR chemistry Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs. Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions. Provides a thorough overview of heterocycles as input in multicomponent reactions Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry Explains the methodology of using on-resin MCRs to produce heterocycle compounds Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic chemists in academia and industry alike.

Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119006325
Total Pages : 480 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis by : Jean Rodriguez

Download or read book Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis written by Jean Rodriguez and published by John Wiley & Sons. This book was released on 2015-04-03 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining the important research topic of multiple bond-formingtransformations with green chemistry, this book helps chemistsidentify recent sustainable stereoselective syntheticsequences. • Combines the important research topic ofmultiple bond-forming transformations with green chemistry andsustainable development • Offers a valuable resource for preparingcompounds with multiple stereogenic centers, an important field forsynthetic chemists • Organizes chapters by molecular structureof final products, making for a handbook-style resource • Discusses applications of the synthesisof natural products and of drug intermediates • Brings together otherwise-scatteredinformation about a number of key, efficient chemical reactions

Green Techniques for Organic Synthesis and Medicinal Chemistry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119288177
Total Pages : 728 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Green Techniques for Organic Synthesis and Medicinal Chemistry by : Wei Zhang

Download or read book Green Techniques for Organic Synthesis and Medicinal Chemistry written by Wei Zhang and published by John Wiley & Sons. This book was released on 2018-01-16 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.

Green Organic Reactions

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Author :
Publisher : Springer Nature
ISBN 13 : 9813368977
Total Pages : 349 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Green Organic Reactions by : Gopinathan Anilkumar

Download or read book Green Organic Reactions written by Gopinathan Anilkumar and published by Springer Nature. This book was released on 2021-03-27 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents important developments and applications of green chemistry, especially in the field of organic chemistry. The chapters give a brief account of green organic reactions in water, green organic reactions using microwave and in solvent-free conditions. In depth discussions on the green aspects of ionic liquids, flow reactions, and recoverable catalysts are provided in this book. An exclusive chapter devoted to green Lewis acid is also included. The potential of supercritical fluids as green solvents in various areas of organic reactions is explained as well. This book will be a valuable reference for beginners as well as advanced researchers interested in green organic chemistry.

Multicomponent Reactions

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Author :
Publisher : CRC Press
ISBN 13 : 1498734197
Total Pages : 409 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Multicomponent Reactions by : K.L. Ameta, Ph.D.

Download or read book Multicomponent Reactions written by K.L. Ameta, Ph.D. and published by CRC Press. This book was released on 2017-09-20 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.

Green Metrics

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527695265
Total Pages : 400 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Green Metrics by :

Download or read book Green Metrics written by and published by John Wiley & Sons. This book was released on 2018-02-01 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 11 of the Handbook of Green Chemistry series identifies, explains and expands on green chemistry and engineering metrics, describing how the two work together, backed by numerous practical applications. Up-to-date and authoritative, this ready reference covers the development and application of sustainable chemistry along with engineering metrics in both academia and industry, providing the latest information on fundamental aspects of metrics, practical realizations and example case studies. Additionally, it outlines how metrics have been used to facilitate developments in sustainable and green chemistry. The different concepts of and approaches to metrics are applied to fundamental problems in chemistry and the focus is firmly placed on their use to promote the development and implementation of more sustainable and green chemistry and technology in the production of chemicals and related products. Starting with molecular design, followed by chemical route evaluation, chemical process metrics and product assessment, by the end readers will have a complete set of metrics to choose from as they move a chemical conception to final product. Of high interest to academics and chemists working in industry.

Advances in Heterocyclic Chemistry

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Author :
Publisher : Elsevier
ISBN 13 : 0443297436
Total Pages : 270 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Advances in Heterocyclic Chemistry by :

Download or read book Advances in Heterocyclic Chemistry written by and published by Elsevier. This book was released on 2024-05-27 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Heterocyclic Chemistry, Volume 144 highlights new advances in the field, with this volume presenting chapters on Metal free C-H functionalization of aromatic and non-aromatic heterocyclic systems, Divergent Total Synthesis of Indolizidine-, Quinolizidine-, and Decahydroquinoline-type Poison-frog Alkaloids, A perspective on the synthetic potential of bio-based building blocks for heterocyclic chemistry, Recent advances in the synthesis of 3,3-disubstituted oxetanes, and Pyrrole-based chemosensors: Recent trends. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Advances in Heterocyclic Chemistry

Multicomponent Reactions

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118863976
Total Pages : 528 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Multicomponent Reactions by : Raquel P. Herrera

Download or read book Multicomponent Reactions written by Raquel P. Herrera and published by John Wiley & Sons. This book was released on 2015-04-01 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing a dynamic aspect of organic chemistry, this bookdescribes synthetic strategies and applications for multicomponentreactions – including key routes for synthesizing complexmolecules. • Illustrates the crucial role and theimportant utility of multicomponent reactions (MCRs) to organicsyntheses • Compiles novel and efficient syntheticmulticomponent procedures to give readers a complete picture ofthis class of organic reactions • Helps readers to design efficient andpractical transformations using multicomponent reactionstrategies • Describes reaction background,applications to synthesize complex molecules and drugs, andreaction mechanisms

Modern Strategies for Heterocycle Synthesis

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Author :
Publisher : MDPI
ISBN 13 : 3036503404
Total Pages : 372 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Modern Strategies for Heterocycle Synthesis by : Gianfranco Favi

Download or read book Modern Strategies for Heterocycle Synthesis written by Gianfranco Favi and published by MDPI. This book was released on 2021-03-17 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.

Efficiency in Natural Product Total Synthesis

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118940210
Total Pages : 512 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Efficiency in Natural Product Total Synthesis by : Pei-Qiang Huang

Download or read book Efficiency in Natural Product Total Synthesis written by Pei-Qiang Huang and published by John Wiley & Sons. This book was released on 2018-07-24 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals

Reaction Green Metrics

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Author :
Publisher : CRC Press
ISBN 13 : 0429754426
Total Pages : 592 pages
Book Rating : 4.4/5 (297 download)

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Book Synopsis Reaction Green Metrics by : John Andraos

Download or read book Reaction Green Metrics written by John Andraos and published by CRC Press. This book was released on 2018-12-07 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a series of exercises and problems posed in the subject of green metrics. Essentially it is a "how to" book on evaluating the material efficiency, environmental impact, safety-hazard impact, and energy efficiency of any kind of chemical reaction or synthesis plan. Only the essential green metrics in each of these categories are used. The introduction highlights the hierarchy of metrics used throughout the book, explains the structure of how the book is arranged, how the problems are posed, and how the reader is to use the book. Examples refer to themes according to the headings given in the table of contents and are arranged in a hierarchical order. Key Features: The topics cover fundamentals in chemistry and the chemical industry in a blended fashion A unique text covering the fundamentals of green metrics from materials efficiency and environmental and safety-hazard impact, to new green technologies and more The book will be useful in a range of chemistry courses, from early undergraduate to advanced graduate courses, whether based in lectures, tutorials or laboratory experiments Using an extensive glossary of terms used in green metrics, each chapter has a specified theme where the relevant metrics definitions pertaining to that theme will be given with one or two illustrative worked examples Supplemental web-based downloadable material including extra problems, full solutions, Excel files, ChemDraw files, templates, and exercises

Green Synthetic Processes and Procedures

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1788018397
Total Pages : 432 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Green Synthetic Processes and Procedures by : Roberto Ballini

Download or read book Green Synthetic Processes and Procedures written by Roberto Ballini and published by Royal Society of Chemistry. This book was released on 2019-06-27 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The principles of Green Chemistry aim to improve the sustainability of chemical processes and reduce the generation of hazardous substances. There has been great growth in the field over the past few years and the number of research groups working in this area is still increasing. Now one of the biggest challenges is to embed the Green Chemistry ideals of safety and sustainability as standard, both in industry and academia. In order to do this, it is important to create resources that detail different applications and approaches. Green Synthetic Processes and Procedures brings together expert contributors from across a number of areas of green synthesis to cover a diverse array of subjects. Providing a thorough overview of the current green synthetic toolbox, from biocatalysis to sonochemistry, this book is a useful resource for any chemist wishing to design cleaner and safer processes.

Synthesis of 4- to 7-membered Heterocycles by Ring Expansion

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Author :
Publisher : Springer
ISBN 13 : 3319249606
Total Pages : 367 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Synthesis of 4- to 7-membered Heterocycles by Ring Expansion by : Matthias D’hooghe

Download or read book Synthesis of 4- to 7-membered Heterocycles by Ring Expansion written by Matthias D’hooghe and published by Springer. This book was released on 2015-12-14 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.

Green Metrics, Volume 11

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527326448
Total Pages : 314 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Green Metrics, Volume 11 by :

Download or read book Green Metrics, Volume 11 written by and published by John Wiley & Sons. This book was released on 2018-05-07 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 11 of the Handbook of Green Chemistry series identifies, explains and expands on green chemistry and engineering metrics, describing how the two work together, backed by numerous practical applications. Up-to-date and authoritative, this ready reference covers the development and application of sustainable chemistry along with engineering metrics in both academia and industry, providing the latest information on fundamental aspects of metrics, practical realizations and example case studies. Additionally, it outlines how metrics have been used to facilitate developments in sustainable and green chemistry. The different concepts of and approaches to metrics are applied to fundamental problems in chemistry and the focus is firmly placed on their use to promote the development and implementation of more sustainable and green chemistry and technology in the production of chemicals and related products. Starting with molecular design, followed by chemical route evaluation, chemical process metrics and product assessment, by the end readers will have a complete set of metrics to choose from as they move a chemical conception to final product. Of high interest to academics and chemists working in industry.