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Author : Diane H. Russell
Publisher :
ISBN 13 : 9780890041161
Total Pages : 178 pages
Book Rating : 4.0/5 (411 download)
Download or read book Polyamines as Biochemical Markers of Normal and Malignant Growth written by Diane H. Russell and published by . This book was released on 1978 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Tomonobu Kusano
Publisher : Springer
ISBN 13 : 443155212X
Total Pages : 324 pages
Book Rating : 4.4/5 (315 download)
Download or read book Polyamines written by Tomonobu Kusano and published by Springer. This book was released on 2015-01-07 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers key topics in polyamine research from a range of organisms, including plants, mammals, and prokaryotes such as bacteria and archaea. The book provides an introduction to general concepts in the field of polyamine research, as well as more detailed information. With the availability of genome sequence data from a broad range of organisms, the evolution of the genes involved in polyamine metabolism is discussed. The mode of action of polyamines has been shown to be dependent on cation channels, and this mechanism is described in the book. The origin of polyamine transporters (from bacteria, yeasts, and plants) is described. The various effects of polyamines on growth and survival are also documented. The book details the mechanisms of polyamine homeostasis and the role of polyamine molecules as precursors of secondary metabolites such as plant alkaloids and toxins derived from spiders and wasps. The role of polyamines in longevity and disease is discussed. A link between polyamine contents and cancer progression is reported, as is the use of polyamine metabolites as diagnostic markers in the initial stages of cancer. Moreover, a novel approach that utilizes the polyamine pathway of a parasite as a drug target in African sleeping sickness is described. Therefore, this book is a valuable resource, both as a textbook for undergraduate and graduate students and also as a reference book for front-line polyamine researchers.
Author : Kazutomo Imahori
Publisher : VSP
ISBN 13 : 9789067640428
Total Pages : 548 pages
Book Rating : 4.6/5 (44 download)
Download or read book Polyamines written by Kazutomo Imahori and published by VSP. This book was released on 1985-12 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: The significance of polyamines in cell proliferation and carcinogenesis has stimulated further research interest in their biochemistry and metabolism. These papers, which update the available literature on polyamines, are grouped into four main areas: the metabolism of polyamines; the effect of polyamines on cellular metabolism; inhibitors of polyamine metabolism and their clinical relevance; application to diagnosis and prognosis. The Proceedings include contributions from a wide range of research interests with special emphasis being placed on the clinical aspects of these compounds.
Author : Diane H. Russell
Publisher :
ISBN 13 :
Total Pages : 492 pages
Book Rating : 4.3/5 (91 download)
Download or read book Polyamines in Normal and Neoplastic Growth written by Diane H. Russell and published by . This book was released on 1973 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Uriel Bachrach
Publisher : CRC Press
ISBN 13 : 9780849368097
Total Pages : 328 pages
Book Rating : 4.3/5 (68 download)
Download or read book The Physiology of Polyamines written by Uriel Bachrach and published by CRC Press. This book was released on 1989-03-31 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: The state of the art in the area of polyamines is presented in this useful, two-volume publication. Basic information describing the role of polyamines in the processes of growth and differentiation is given. Also included are data on the regulation of polyamine biosynthesis and metabolism and their interactions with nucleic acids. Several chapters are devoted to the role of polyamines in various aspects of plant biology, with a special emphasis on their participation in the response of plants to extreme environments. Special attention is given to the use of inhibitors of polyamine biosynthesis as potential antitumor and antiproliferative agents. Additionally, recent progress in the molecular biology and genetic engineering of genes coding for polyamine biosynthetic enzymes is described. Cancer researchers, biologists, geneticists, biochemists, physiologists, and clinicians will find this volume indispensible. Contents VOLUME II: POLYAMINES IN MICROBES. Polyamines and the Growth of Bacteria and Viruses. Polyamines in Thermophiles. Propylamine Transfer Reactions in Thermophilic Archaebacteria: Enzymological Aspects and Comparative Biochemistry. Microbial Mutants Deficient in Polyamine Synthesis. Regulation of the Putrescine Biosynthetic Genes (SpeA, speB, and speC) in Escherichia coli. Utilization of L-Arginine, L-Ornithine, Agmatine, and Putrescine as the Major Source of Nitrogen and Its Control in Escherichia coli. POLYAMINES AND PLANTS. Polyamines and Plant Response to Stress. Polyamines and Plant Growth and Development. Polyamines and Plant Hormones. Polyamines in Plant Mutants. POLYAMINES AND DISEASES. Polyamines in Health and Disease. Polyamine Metabolism and Neoplastic Growth: A Programmed Deregulation? Polyamines as Markers of Malignancy. Polyamines as Indicators of Disease Activity and Response to Therapy in Cancer Patients. Inhibitors of Polyamine Biosynthesis as Therapeutic Agents. Clinical Studies of a- Difluoromethylornithine and a-Interferon in Cancer Patients. Changes in Polyamine Metabolism in Tumor-Bearing Hosts with Total Parenteral Nutrition and Intravenous Infusion of a-Difluoromethylornithine. Index. c. 328 pp., 7x10, due February 1989, ISBN-0-8493-6809-X.
Author : Prakash Chandra
Publisher : Springer Science & Business Media
ISBN 13 : 1468444549
Total Pages : 631 pages
Book Rating : 4.4/5 (684 download)
Download or read book Biochemical and Biological Markers of Neoplastic Transformation written by Prakash Chandra and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is arecord of the proceedings of a NATO Advanced Study institute on "Biochemical and Bio logical Markers of Neoplastic Transformation" held September 28 - October 8, 1981, at Corfu, Greece. As early as 1860, Rudolf Virchow provided the first genetic concept of cancer by postulating "Omnia ceZZuZa e ceZZuZa ejusdem generis", a modification of the then exisiting cell theory "Omnis ceZZuZa e ceZZuZa". Thus, the idea that all cells originate from the parent cell was extended to the idea that all cancer cells come from the "paren t" cancer cello But how the first cancer cell arose, or in other words, how anormal cell changed to a cancer cell, is, even after 120 years, a mystery. Experimental studies of the past have convinced us that a number of factors contribute to the neoplastic transformation of anormal cell, but our knowledge on the mechanisms involved in this process is still in an embryonic state. In the last few years, however, this field has witnessed a most remarkable advancement cata lyzed by the development of modern technology in the al lied fields of immunology, the production of mono clonal antibodies, molecular biology, and sequencing v PREFACE and cloning of ONC genes. Presently, it is becoming more and more evident to the wishful mind of those engaged in this research that we are approaching a turning point. Thus, an assessment of the present situa tion will be most desirable at this time
Author : Uriel Bachrach
Publisher : CRC Press
ISBN 13 : 1000446379
Total Pages : 394 pages
Book Rating : 4.0/5 (4 download)
Download or read book The Physiology of Polyamines, Volume I written by Uriel Bachrach and published by CRC Press. This book was released on 2021-05-30 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of polyamines is presented in this useful, two-volume publication. Basic information describing the role of polyamines in the processes of growth and differentiation is given. Also included are data on the regulation of polyamine biosynthesis and metabolism and their interactions with nucleic acids. Several chapters are devoted to the role of polyamines in various aspects of plant biology, with a special emphasis on their participation in the response of plants to extreme environments. Special attention is given to the use of inhibitors of polyamine biosynthesis as potential antitumor and antiproliferative agents. Additionally, progress in the molecular biology and genetic engineering of genes coding for polyamine biosynthetic enzymes is described. Cancer researchers, biologists, geneticists, biochemists, physiologists, and clinicians will find this volume indispensable.
Author : Peter McCann
Publisher : Elsevier
ISBN 13 : 0323152325
Total Pages : 388 pages
Book Rating : 4.3/5 (231 download)
Download or read book Inhibition of Polyamine Metabolism written by Peter McCann and published by Elsevier. This book was released on 2012-12-02 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inhibition of Polyamine Metabolism: Biological Significance and Basis for New Therapies provides an overview of the field concerning polyamine biosynthesis inhibitors. The book is comprised of chapters which describe the compounds which are in use; the rationale for the design of such inhibitors; their synthesis and action; their biological effects on mammalian cells and tissues, plants, and microorganisms including protozoal parasites; and a review of the clinical experience with these inhibitors. The major beneficial effect which the wide availability of these inhibitors has had on the field of polyamine research in general is likewise demonstrated. Biochemists, pharmacologist, and cellular physiologists will find this text very useful.
Author :
Publisher :
ISBN 13 :
Total Pages : 584 pages
Book Rating : 4.:/5 (31 download)
Download or read book Third International Symposium, Cancer Therapy by Hyperthermia, Drugs, and Radiation written by and published by . This book was released on 1982 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 584 pages
Book Rating : 4.:/5 (318 download)
Download or read book National Cancer Institute Monograph written by and published by . This book was released on 1982 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gerhard Seifert
Publisher : Springer Science & Business Media
ISBN 13 : 3642713564
Total Pages : 402 pages
Book Rating : 4.6/5 (427 download)
Download or read book Morphological Tumor Markers written by Gerhard Seifert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: New methods in immunocytochemistry and hybridization techniques enable the pathologist active in diagnosis to clarify more effectively problems in the classification and prognosis of tumors. By adopting these methods into his diagnostic repertoire it will be possible to create a closer, more productive connection between morphological diagnosis and clinical work. This volume gives the reader an up-to-date general survey from international experts of the method, technique and practical application of these new procedures.
Author : National Cancer Institute (U.S.)
Publisher :
ISBN 13 :
Total Pages : 584 pages
Book Rating : 4.3/5 (121 download)
Download or read book Third International Symposium, Cancer Therapy by Hyperthermia, Drugs, and Radiation written by National Cancer Institute (U.S.) and published by . This book was released on 1982 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1728 pages
Book Rating : 4.3/5 (91 download)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1728 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Author : Alecsandru Ioan Baba
Publisher :
ISBN 13 : 9789732714577
Total Pages : 787 pages
Book Rating : 4.7/5 (145 download)
Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : G. a. Qureshi
Publisher : VSP
ISBN 13 : 9789067642774
Total Pages : 880 pages
Book Rating : 4.6/5 (427 download)
Download or read book Neurochemical Markers of Degenerative Nervous Diseases and Drug Addiction written by G. a. Qureshi and published by VSP. This book was released on 1998-03 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 0080865461
Total Pages : 361 pages
Book Rating : 4.0/5 (88 download)
Download or read book The Alkaloids: Chemistry and Pharmacology written by and published by Academic Press. This book was released on 1984-01-04 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Alkaloids: Chemistry and Pharmacology
Author :
Publisher :
ISBN 13 :
Total Pages : 1004 pages
Book Rating : 4.E/5 ( download)
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1989 with total page 1004 pages. Available in PDF, EPUB and Kindle. Book excerpt:
