Poisoning And Drug Overdose Sixth Edition

Download Poisoning And Drug Overdose Sixth Edition full books in PDF, epub, and Kindle. Read online Poisoning And Drug Overdose Sixth Edition ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Poisoning and Drug Overdose, Seventh Edition

Author : Kent R. Olson
Publisher : McGraw Hill Professional
ISBN 13 : 0071839801
Total Pages : 752 pages
Book Rating : 4.0/5 (718 download)

DOWNLOAD NOW!

Book Synopsis Poisoning and Drug Overdose, Seventh Edition by : Kent R. Olson

Download or read book Poisoning and Drug Overdose, Seventh Edition written by Kent R. Olson and published by McGraw Hill Professional. This book was released on 2017-12-15 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: The instant-answer guide clinicians turn to first for on-the-spot treatment of poisoning and drug overdose emergencies A Doody’s Core Title for 2019! “...a great addition to any emergency department library when rapid reference is needed to treat and diagnose the poisoned patient.” -- Annals of Emergency Medicine (Reviewing previous edition) Designed to be used during toxicologic emergencies where every moment counts, Poisoning & Drug Overdose, Seventh Edition delivers critical information on the effective diagnosis and treatment of drug-related emergencies and chemical exposures. This at-a-glance guide is enhanced by detailed tables and charts, extensive cross referencing, and a comprehensive index featuring generic, chemical, and brand names. Poisoning & Drug Overdose is divided into four sections: Section 1 leads readers through initial emergency management, including treatment of coma, hypotension, and other common complications; physical and laboratory diagnosis; and methods of decontamination and enhanced elimination of poisons Section II provides detailed information on 150 common drugs and poisons Section III describes the use and side effects of 60 antidotes and therapeutic drugs Section IV describes the medical management of chemical spills and occupations chemical exposures and includes a table of more than 500 industrial chemicals • Thoroughly updated to reflect newly released drugs, new information on existing drugs, and coverage of the latest black box (and other) warnings • NEW to this edition: information on drug-environmental exposure interactions, coverage of environmental toxins such as mold, asbestos, and others

Forging a Poison Prevention and Control System

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309091942
Total Pages : 369 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Forging a Poison Prevention and Control System by : Institute of Medicine

Download or read book Forging a Poison Prevention and Control System written by Institute of Medicine and published by National Academies Press. This book was released on 2004-09-16 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poisoning is a far more serious health problem in the U.S. than has generally been recognized. It is estimated that more than 4 million poisoning episodes occur annually, with approximately 300,000 cases leading to hospitalization. The field of poison prevention provides some of the most celebrated examples of successful public health interventions, yet surprisingly the current poison control "system" is little more than a loose network of poison control centers, poorly integrated into the larger spheres of public health. To increase their effectiveness, efforts to reduce poisoning need to be linked to a national agenda for public health promotion and injury prevention. Forging a Poison Prevention and Control System recommends a future poison control system with a strong public health infrastructure, a national system of regional poison control centers, federal funding to support core poison control activities, and a national poison information system to track major poisoning epidemics and possible acts of bioterrorism. This framework provides a complete "system" that could offer the best poison prevention and patient care services to meet the needs of the nation in the 21st century.

Clinical Management of Poisoning and Drug Overdose

Author : Lester M. Haddad
Publisher :
ISBN 13 : 9780721664095
Total Pages : 0 pages
Book Rating : 4.6/5 (64 download)

DOWNLOAD NOW!

Book Synopsis Clinical Management of Poisoning and Drug Overdose by : Lester M. Haddad

Download or read book Clinical Management of Poisoning and Drug Overdose written by Lester M. Haddad and published by . This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here's a comprehensive and clinically-specific reference on toxicology. The 3rd Edition includes chapters on overdose during rapid-sequence intubation and conscious sedation, management of complications of thrombolytic agents, and the application of hyperbaric medicine in toxicology. Provides the perfect balance of basic pharmacokinetics and clinical management. Contributions are by experts in the field. Contains completely rewritten and reorganized coverage to encompass the background, pharmacology, pathophysiology, diagnosis, and management of each toxin for clinical treatment throughout a patient's hospital stay. Features a new editor--Michael Shannon, MD--whose experience in pediatric emergency medicine expands the text's coverage of pediatrics...and almost 60 new contributing experts who have made original contributions to their field, with a majority certified by the first approved subspecialty board in toxicology. Presents 10 new chapters that cover: pediatric resuscitation, antibiotic hypersensitivity and anaphylaxis, MAO inhibitors and the serotonin syndrome, herbal and alternative medicine, and thrombolytic therapy, and more. OUTSTANDING FEATURES: Uses a clinical approachfor maximum clinical relevance, addressing how toxins affect humans, not animals. Incorporates the experience of many expert authors from numerous specialties for a Comprehensive review of toxicology and an authoritative overview of each specialty. Contains colour plates of toxic natural life, including various snakes, mushrooms, plants, and marine life--a feature unique to this book.

The Toxicologist's Pocket Handbook

Author : Michael J. Derelanko
Publisher : CRC Press
ISBN 13 : 1351857177
Total Pages : 533 pages
Book Rating : 4.3/5 (518 download)

DOWNLOAD NOW!

Book Synopsis The Toxicologist's Pocket Handbook by : Michael J. Derelanko

Download or read book The Toxicologist's Pocket Handbook written by Michael J. Derelanko and published by CRC Press. This book was released on 2017-11-06 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the Toxicologist’s Pocket Handbook, like the first two editions, is a scaled-down version of the best-selling Handbook of Toxicology. It provides the most frequently used toxicology reference information in a convenient pocket-sized book. The format remains the same as the earlier editions to allow basic reference information to be located quickly, with the information placed in sections specific to subspecialties of toxicology. A detailed table of contents lists all tables and figures contained in the book by section. This expanded edition contains a number of tables not found in the second edition added to sections on lab animals, general toxicology, dermal and ocular toxicology, genetic toxicology/carcinogenesis, neurotoxicology, immunotoxicology, reproductive/developmental toxicology, industrial chemical, and pharmaceutical toxicology. New information is presented for additional laboratory animals such as swine and primates, infusion recommendations, newer methods such as the local lymph node assay, and reference safety pharmacology values for standard species. Additional information on typical genetic toxicology and immunotoxicology assays as well as in vitro assays for eye irritation are provided. Some tables from the second edition have been updated to include new information that has arisen since the earlier edition went to press. Information from the second edition, such as regulatory requirements that are no longer applicable, has been deleted.

Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose

Author : Michael W. Shannon
Publisher : Saunders
ISBN 13 : 9780721606934
Total Pages : 0 pages
Book Rating : 4.6/5 (69 download)

DOWNLOAD NOW!

Book Synopsis Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose by : Michael W. Shannon

Download or read book Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose written by Michael W. Shannon and published by Saunders. This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edition is a reference for information related to the clinical management of children and adults whose health has been effected or potentially effected by toxic agents, including drugs, environmental threats, and natural toxins.

Medical Toxicology

Author : Richard C. Dart
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781728454
Total Pages : 1990 pages
Book Rating : 4.7/5 (284 download)

DOWNLOAD NOW!

Book Synopsis Medical Toxicology by : Richard C. Dart

Download or read book Medical Toxicology written by Richard C. Dart and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 1990 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised and updated Third Edition of the classic Medical Toxicology is the definitive reference on the management of poisoned patients. More than 300 well-organized chapters written by eminent authorities guide clinicians through the diagnosis and treatment of every poisoning or drug overdose. Chapter outlines, headings, and a detailed index enable readers to quickly locate exactly the information they need. This edition includes new chapters on biological and chemical weapons and on diagnosis of patients with apparent symptoms of poisoning when the cause is unknown. The book includes comparative commentary on toxicology practice in the United States, Europe, Australia, and Asia. Compatibility: BlackBerry® OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile™ Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC

Poisoning & Drug Overdose, 5th Edition

Author : Kent Russell Olson
Publisher : McGraw-Hill Professional
ISBN 13 : 0071443339
Total Pages : 752 pages
Book Rating : 4.0/5 (714 download)

DOWNLOAD NOW!

Book Synopsis Poisoning & Drug Overdose, 5th Edition by : Kent Russell Olson

Download or read book Poisoning & Drug Overdose, 5th Edition written by Kent Russell Olson and published by McGraw-Hill Professional. This book was released on 2006-09-18 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: The leading source for toxicologic emergencies -- revised and updated! A Doody's Core Title ESSENTIAL PURCHASE! 4 STAR DOODY'S REVIEW! "This is an excellent resource for poison control centers, toxicologists, and healthcare practitioners for the diagnosis, treatment, and management of poisonings as a result of exposure to a wide variety of industrial, therapeutic, illicit, and environmental chemicals."--Doody's Review Service With each bestselling edition, Poisoning & Drug Overdose has helped poison control staff, medical toxicologists, and emergency physicians respond to drug-related emergencies and chemical exposures. The new edition of this exceptional, at-a-glance guide offers the latest advice needed for the effective diagnosis and treatment of poisoning and drug overdose. The Fifth Edition features: Critical insights into timely topics such as biological warfare agents and the newest antidotes Updated information on industrial chemicals, including the most recent regulatory exposure limits Expanded information, including special pregnancy considerations Easy-to-read text and tables containing specific drug dosage information Detailed table summarizing current toxicity and workplace exposure guidelines for more than 500 industrial chemicals Extensive cross-referencing Comprehensive index featuring generic, chemical, and brand names for many drugs and commercial products

Critical Care Obstetrics

Author : Michael A. Belfort
Publisher : Wiley-Blackwell
ISBN 13 : 047075981X
Total Pages : 704 pages
Book Rating : 4.4/5 (77 download)

DOWNLOAD NOW!

Book Synopsis Critical Care Obstetrics by : Michael A. Belfort

Download or read book Critical Care Obstetrics written by Michael A. Belfort and published by Wiley-Blackwell. This book was released on 2008-04-15 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth edition of Critical Care Obstetrics has been extensively revised to reflect the advances that have been made in maternal-fetal medicine. This edition contains 14 brand new chapters written by the field's leading physicians. Critical Care Obstetrics, 4/e, offers expanded coverage in areas vital to intensive care management, including Neonatal Resuscitation, The Organ Transplant Obstetrical Patient, and Ethical Considerations This practical guide and reference will be of invaluable assistance to obstetricians, and primary care physicians, in both the treatment and referral of high-risk patients.

Pharma

Author : Gerald Posner
Publisher : Simon and Schuster
ISBN 13 : 1501152041
Total Pages : 816 pages
Book Rating : 4.5/5 (11 download)

DOWNLOAD NOW!

Book Synopsis Pharma by : Gerald Posner

Download or read book Pharma written by Gerald Posner and published by Simon and Schuster. This book was released on 2020-03-10 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: Award-winning journalist and New York Times bestselling author Gerald Posner reveals the heroes and villains of the trillion-dollar-a-year pharmaceutical industry and delivers “a withering and encyclopedic indictment of a drug industry that often seems to prioritize profits over patients (The New York Times Book Review). Pharmaceutical breakthroughs such as antibiotics and vaccines rank among some of the greatest advancements in human history. Yet exorbitant prices for life-saving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on prescription opioids have caused many to lose faith in drug companies. Now, Americans are demanding a national reckoning with a monolithic industry. “Gerald’s dogged reporting, sets Pharma apart from all books on this subject” (The Washington Standard) as we are introduced to brilliant scientists, incorruptible government regulators, and brave whistleblowers facing off against company executives often blinded by greed. A business that profits from treating ills can create far deadlier problems than it cures. Addictive products are part of the industry’s DNA, from the days when corner drugstores sold morphine, heroin, and cocaine, to the past two decades of dangerously overprescribed opioids. Pharma also uncovers the real story of the Sacklers, the family that became one of America’s wealthiest from the success of OxyContin, their blockbuster narcotic painkiller at the center of the opioid crisis. Relying on thousands of pages of government and corporate archives, dozens of hours of interviews with insiders, and previously classified FBI files, Posner exposes the secrets of the Sacklers’ rise to power—revelations that have long been buried under a byzantine web of interlocking companies with ever-changing names and hidden owners. The unexpected twists and turns of the Sackler family saga are told against the startling chronicle of a powerful industry that sits at the intersection of public health and profits. “Explosively, even addictively, readable” (Booklist, starred review), Pharma reveals how and why American drug companies have put earnings ahead of patients.

World Report on Child Injury Prevention

Author : M. M. Peden
Publisher : World Health Organization
ISBN 13 : 9241563575
Total Pages : 233 pages
Book Rating : 4.2/5 (415 download)

DOWNLOAD NOW!

Book Synopsis World Report on Child Injury Prevention by : M. M. Peden

Download or read book World Report on Child Injury Prevention written by M. M. Peden and published by World Health Organization. This book was released on 2008 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Child injuries are largely absent from child survival initiatives presently on the global agenda. Through this report, the World Health Organization, the United Nations Children's Fund and many partners have set out to elevate child injury to a priority for the global public health and development communities. It should be seen as a complement to the UN Secretary-General's study on violence against children released in late 2006 (that report addressed violence-related or intentional injuries). Both reports suggest that child injury and violence prevention programs need to be integrated into child survival and other broad strategies focused on improving the lives of children. Evidence demonstrates the dramatic successes in child injury prevention in countries which have made a concerted effort. These results make a case for increasing investments in human resources and institutional capacities. Implementing proven interventions could save more than a thousand children's lives a day.--p. vii.

Mechanisms of Drug Toxicity

Author : H. Rašková
Publisher : Elsevier
ISBN 13 : 1483157202
Total Pages : 113 pages
Book Rating : 4.4/5 (831 download)

DOWNLOAD NOW!

Book Synopsis Mechanisms of Drug Toxicity by : H. Rašková

Download or read book Mechanisms of Drug Toxicity written by H. Rašková and published by Elsevier. This book was released on 2013-10-22 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of Drug Toxicity, Volume 4 presents the proceedings of the 3rd International Pharmacological Meeting held in Sao Paulo, Brazil in 1966. The book discusses the drug-induced pathobiotic effects; the mechanisms of adverse reactions; and enzyme induction in the mechanism of chronic toxicity. The text also describes the influence of inducing substances on the growth of liver and microsomal electron transport systems; the quantitative aspects of chronic toxicity; and the facts and fallacies in predicting drug effects in human.

Medical Pharmacology and Therapeutics E-Book

Author : Derek G. Waller
Publisher : Elsevier Health Sciences
ISBN 13 : 0702055034
Total Pages : 741 pages
Book Rating : 4.7/5 (2 download)

DOWNLOAD NOW!

Book Synopsis Medical Pharmacology and Therapeutics E-Book by : Derek G. Waller

Download or read book Medical Pharmacology and Therapeutics E-Book written by Derek G. Waller and published by Elsevier Health Sciences. This book was released on 2013-08-07 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice

Goldfrank's Toxicologic Emergencies, Eleventh Edition

Author : Lewis S. Nelson
Publisher : McGraw Hill Professional
ISBN 13 : 1259859592
Total Pages : pages
Book Rating : 4.2/5 (598 download)

DOWNLOAD NOW!

Book Synopsis Goldfrank's Toxicologic Emergencies, Eleventh Edition by : Lewis S. Nelson

Download or read book Goldfrank's Toxicologic Emergencies, Eleventh Edition written by Lewis S. Nelson and published by McGraw Hill Professional. This book was released on 2018-08-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Goldfrank’s is the premier toxicology textbook that should be in every emergency department or poison center library. Whether you are a student, resident, or faculty, there is something here for you. If you are a toxicology fellow or poison specialist studying for your boards, this is your go-to book. I highly recommend this work... —The Journal of Emergency Medicine The best edition yet of the landmark text in medical toxicology A Doody’s Core Title for 2020! Covering every aspect of poison management, this indispensable case-based resource has been thoroughly refreshed to deliver evidence-based principles viewed through the lens of an active bedside clinical practice. In no other reference will you find such a diverse roster of esteemed editors and authors who deliver expert insights into every type of toxicologic emergency, whether due to substance abuse or exposure to toxins. Fully referenced and supported by a cohesive organization and full-color format, Goldfrank’s begins with a historical perspective on medical toxicology principles and the general approach to the patient. It then progresses to the fundamental principles of medical toxicology, encompassing biochemical and molecular concepts; the effect of xenobiotics on vital organs and body systems; and toxicologic principles in special populations. The Eleventh Edition of Goldfrank’s Toxicologic Emergencies is the most rigorous volume to date, driven by a precise analysis of the latest medical literature and complex cases designed to facilitate differential diagnosis. New to this Edition: • Additional cases and “Special Considerations” chapters designed to enhance clinical decision-making and patient outcomes • New “Antidotes in Depth” provides timely, critical information on toxicologic treatment strategies • New content on toxicogenomics explores its increasingly important role in predictive toxicology • Chapter-ending bulleted summaries of key points • Updated coverage of synthetics such as “K2” • Revised chapters on medical, clinical, and chemical toxicology include updated insights on poison emergencies, treatment strategies, and risk assessment tools

OD

Author : Nancy D. Campbell
Publisher : MIT Press
ISBN 13 : 0262357488
Total Pages : 425 pages
Book Rating : 4.2/5 (623 download)

DOWNLOAD NOW!

Book Synopsis OD by : Nancy D. Campbell

Download or read book OD written by Nancy D. Campbell and published by MIT Press. This book was released on 2020-03-03 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The history of an unnatural disaster—drug overdose—and the emergence of naloxone as a social and technological solution. For years, drug overdose was unmentionable in polite society. OD was understood to be something that took place in dark alleys—an ugly death awaiting social deviants—neither scientifically nor clinically interesting. But over the last several years, overdose prevention has become the unlikely object of a social movement, powered by the miracle drug naloxone. In OD, Nancy Campbell charts the emergence of naloxone as a technological fix for overdose and describes the remaking of overdose into an experience recognized as common, predictable, patterned—and, above all, preventable. Naloxone, which made resuscitation, rescue, and “reversal” after an overdose possible, became a tool for shifting law, policy, clinical medicine, and science toward harm reduction. Liberated from emergency room protocols and distributed in take-home kits to non-medical professionals, it also became a tool of empowerment. After recounting the prehistory of naloxone—the early treatment of OD as a problem of poisoning, the development of nalorphine (naloxone's predecessor), the idea of “reanimatology”—Campbell describes how naloxone emerged as a tool of harm reduction. She reports on naloxone use in far-flung locations that include post-Thatcherite Britain, rural New Mexico, and cities and towns in Massachusetts. Drawing on interviews with approximately sixty advocates, drug users, former users, friends, families, witnesses, clinicians, and scientists—whom she calls the “protagonists” of her story—Campbell tells a story of saving lives amid the complex, difficult conditions of an unfolding unnatural disaster.

Recognition and Management of Pesticide Poisonings (5th Ed. )

Author : J. Routt Reigart
Publisher : DIANE Publishing
ISBN 13 : 1437914527
Total Pages : 238 pages
Book Rating : 4.4/5 (379 download)

DOWNLOAD NOW!

Book Synopsis Recognition and Management of Pesticide Poisonings (5th Ed. ) by : J. Routt Reigart

Download or read book Recognition and Management of Pesticide Poisonings (5th Ed. ) written by J. Routt Reigart and published by DIANE Publishing. This book was released on 2009-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 5th ed. is an update and expansion of the 1989 4th ed. This EPA manual provides health professionals with information on the health hazards of pesticides currently in use, and current consensus recommendations for management of poisonings and injuries caused by them. As with previous updates, this new ed. incorporates new pesticide products that are not necessarily widely known among health professionals. Contents: (1) General Information: Introduction; General Principles in the Management of Acute Pesticide Poisonings; Environmental and Occupational History; (2) Insecticides; (3) Herbicides; (4) Other Pesticides; (5) Index of Signs and Symptoms; Index of Pesticide Products. Charts and tables.

Poisoning in the Modern World

Author : Ozgur Karcioglu
Publisher : BoD – Books on Demand
ISBN 13 : 1838807853
Total Pages : 130 pages
Book Rating : 4.8/5 (388 download)

DOWNLOAD NOW!

Book Synopsis Poisoning in the Modern World by : Ozgur Karcioglu

Download or read book Poisoning in the Modern World written by Ozgur Karcioglu and published by BoD – Books on Demand. This book was released on 2019-06-19 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.

Pain Management and the Opioid Epidemic

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!

Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.