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Plant Glycobiology A Sweet World Of Glycans Glycoproteins Glycolipids And Carbohydrate Binding Proteins
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Book Synopsis Plant Glycobiology - A Sweet World of Glycans, Glycoproteins, Glycolipids, and Carbohydrate-Binding Proteins by : Els J. M. Van Damme
Download or read book Plant Glycobiology - A Sweet World of Glycans, Glycoproteins, Glycolipids, and Carbohydrate-Binding Proteins written by Els J. M. Van Damme and published by Frontiers Media SA. This book was released on 2021-10-21 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Plant Glycobiology – a sweet world of lectins, glycoproteins, glycolipids and glycans by : Els J. M. Van Damme
Download or read book Plant Glycobiology – a sweet world of lectins, glycoproteins, glycolipids and glycans written by Els J. M. Van Damme and published by Frontiers Media SA. This book was released on 2015-02-12 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants synthesize a wide variety of unique glycan structures which play essential roles during the life cycle of the plant. Being omnipresent throughout the plant kingdom, ranging from simple green algae to modern flowering plants, glycans contribute to many diverse processes. Glycans can function as structural components in the plant cell wall, assist in the folding of nascent proteins, act as signaling molecules in plant defense responses or (ER) stress pathways, or serve within the energy metabolism of a plant. In most cases, glycans are attached to other macromolecules to form so-called glycoconjugates (e.g. glycoproteins, proteoglycans and glycolipids), but they can also be present as free entities residing in the plant cell. Next to the broad, complex set of glycans, plants also evolved an elaborate collection of lectins or proteins with a lectin-like domain, which can recognize and bind to endogenous (plants-own) or exogenous (foreign) glycans. Though still poorly understood in plants, the dynamic interactions between lectins and carbohydrate structures are suggested to be involved in gene transcription, protein folding, protein transport, cell adhesion, signaling as well as defense responses. As such, a complex and largely undetermined glycan-interactome is established inside plant cells, between cells and their surrounding matrix, inside the extracellular matrix, and even between organisms. Studying the biological roles of plant glycans will enable to better understand plant development and physiology in order to fully exploit plants for food, feed and production of pharmaceutical proteins. In this Research Topic, we want to provide a platform for articles describing the latest research, perspectives and methodologies related to the fascinating world of plant glycobiology, with a focus on following subjects: 1. Identification and characterization of plant glycans, their biosynthetic and degradation enzymes 2. Characterization of plant lectins and glycoproteins 3. Plant glycans in the plant’s energy metabolism 4. Role of plant glycans in plant defense signaling 5. Use of plant lectins in pest control 6. Plant lectins as new tools in human medicine 7. Glyco-engineering in plants
Book Synopsis Essentials of Glycobiology by : Ajit Varki
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Book Synopsis Structural Glycobiology by : Elizabeth Yuriev
Download or read book Structural Glycobiology written by Elizabeth Yuriev and published by CRC Press. This book was released on 2012-09-27 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural Glycobiology covers the experimental, theoretical, and alternative technologies used in the study of the structural basis for the diverse biological roles of carbohydrates. The book overviews the application of specialized technologies to the study of carbohydrates in biology, reviews relevant and current research in the field, and is illustrated throughout by specific examples of how research investigations have yielded key structural and associated biological data on carbohydrates and glycolipids. In particular, the book focuses on: X-ray crystallography and small-angle scattering, NMR, and cryo-electron microscopy techniques Theoretical (modeling-based) approaches, such as molecular mechanics, molecular dynamics, free energy calculations, and carbohydrate docking Alternative techniques for yielding structural information on carbohydrates from complex biological samples Carbohydrates in medicine, specifically in areas that have been directly impacted by our understanding of the structural role of carbohydrates in immune recognition: cancer, organ transplantation, and infection
Book Synopsis Introduction to Glycobiology by : Maureen E. Taylor
Download or read book Introduction to Glycobiology written by Maureen E. Taylor and published by Oxford University Press. This book was released on 2011-04-21 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level and their clinical relevance.
Download or read book Glycobiology written by Minoru Fukuda and published by Elsevier. This book was released on 2006-11-14 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade, there has been an explosion of progress in understanding the roles of carbohydrates in biological systems. This explosive progress was made with the efforts in determining the roles of carbohydrates in immunology, neurobiology and many other disciplines, examining each unique system and employing new technology. This volume represents the first of three in the Methods in Enzymology series, including Glycomics (vol. 416) and Functional Glycomics (vol. 417), dedicated to disseminating information on methods in determining the biological roles of carbohydrates. These books are designed to provide an introduction of new methods to a large variety of readers who would like to participate in and contribute to the advancement of glycobiology. The methods covered include structural analysis of carbohydrates, biological and chemical synthesis of carbohydrates, expression and determination of ligands for carbohydrate-binding proteins, gene expression profiling including micro array, and generation of gene knockout mice and their phenotype analyses.
Book Synopsis Glycobiology Protocols by : Inka Brockhausen
Download or read book Glycobiology Protocols written by Inka Brockhausen and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycobiology involves studies of complex carbohydrates and posttrans- tional modifications of proteins, and has become an important interdiscip- nary field encompassing chemistry, biochemistry, biology, physiology, and pathology. Although initial research was directed toward elucidation of the different carbohydrate structures and the enzymes synthesizing them, the field has now moved toward identifying the functions of carbohydrates. The pro- cols described in Glycobiology Protocols form a solid basis for investigations of glycan functions in health and disease. The cloning of many of the genes participating in glycosylation processes has helped to enhance our knowledge of how glycosylation is controlled, but has also added another dimension of complexity to the great heterogeneous variety of the structures of the oligos- charides of glycoproteins, proteoglycans, and glycolipids. A family of similar enzyme proteins exists for each glycosylation step. Glycosyltransferases are extremely specific for both the nucleotide sugar donor and the acceptor s- strate, but many other factors control sugar transfer, including the locali- tion and topology of enzymes, cofactors, possible chaperone proteins, and the availability of sugar acceptor substrates. The analysis of the intracellular organization of glycosylation and of the factors controlling the activities of the participating enzymes in the cell are important areas that need more research efforts. Another challenge for future research is to understand the glycodynamics of a cell, that is, how the cell responds to stimuli leading to biological and pathological changes in terms of alterations in glycosylation, and how this affects the biology of the cell.
Book Synopsis Functional and Molecular Glycobiology by : Dr Susan Brooks
Download or read book Functional and Molecular Glycobiology written by Dr Susan Brooks and published by Taylor & Francis. This book was released on 2023-06-14 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional and Molecular Glycobiology explains the chemistry of carbohydrates, and the biosynthesis and diversity of different types of glycans. It looks at the functional role of glycoconjugate compounds in normal cellular processes, in both disease and development. The book also describes how these compounds can be studied, analysed and manipulated for use in biotechnology. Functional and Molecular Glycobiology is a unique introduction to the field bridging the gap between introductory books and current research.
Book Synopsis Transforming Glycoscience by : National Research Council
Download or read book Transforming Glycoscience written by National Research Council and published by National Academies Press. This book was released on 2012-10-23 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans--also known as carbohydrates, saccharides, or simply as sugars--play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.
Book Synopsis Chemical Biology of Glycoproteins by : Zhongping Tan
Download or read book Chemical Biology of Glycoproteins written by Zhongping Tan and published by Royal Society of Chemistry. This book was released on 2017-03-20 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycans play a vital role in modulating protein structure and function from involvement in protein folding, solubility and stability to regulation of tissue distribution, recognition specificity, and biological activity. They can act as both positive and negative regulators of protein function, providing an additional level of control with respect to genetic and environmental conditions. Due to the complexity of glycosylated protein forms, elucidating structural and functional information has been challenging task for researchers but recent development of chemical biology-based tools and techniques is bridging these knowledge gaps. This book provides a thorough review of the current state of glycoprotein chemical biology, describing the development and application of glycoprotein and glycan synthesis technologies for understanding and manipulating protein glycosylation.
Book Synopsis Glycosciences by : Hans-Joachim Gabius
Download or read book Glycosciences written by Hans-Joachim Gabius and published by . This book was released on 1997 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of the topic, ranging from basic molecular research to clinical applications. Critical reviews by leading experts in each field summarize the state of knowledge and discuss the anticipated benefits of novel approaches and strategies. These include the impact of modern analysis techniques on glycobiology, the use of synthetic neoglycoproteins, or the clinical consequences of new insights into the physiological role of lectins and glycoconjugates in pathology, oncology, immunity, neuroscience and reproduction medicine. Throughout, the aim is to separate realistic applications from mere hopes.
Book Synopsis Molecular Glycobiology by : Minoru Fukuda
Download or read book Molecular Glycobiology written by Minoru Fukuda and published by Oxford University Press. This book was released on 1994 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cell surface carbohydrates play critical roles in cell-cell interaction. In recent years, major advances have been made in understanding the molecular mechanisms of these processes. Genes encoding glycosyltransferases that synthesize unique oligosaccharides have been isolated, allowing the correlation of specific oligosaccharide structures with function. This book brings together leading researchers to describe our current knowledge in this important area of modern biology. Particular emphasis is given to cell-type-specific carbohydrate expression and the carbohydrates and proteins involved in cell recognition. Also included is a full discussion of key experimental approaches such as chemical synthesis and the three-dimensional structural analysis of carbohydrates." "Molecular Glycobiology is a timely synopsis of this exciting and rapidly expanding field. It provides both an up-to-date description of the subject and leading researchers' views of likely future developments. As such, this volume will be invaluable for active researchers in glycobiology and medicine. However, its easily readable style will also appeal to non-specialists who need an authoritative but accessible text on this subject."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
Download or read book Glycobiology written by Minoru Fukuda and published by Irl Press. This book was released on 1993 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycobiology is now an area of intense research activity due to a growing awareness of the important biological roles of glycoproteins and the development of recombinant glycoproteins for therapeutic purposes. This book describes detailed protocols for all the main methods currently used to elucidate the structure and biosynthesis of glycoproteins. It covers the isolation, fractionation, and structural characterization of glycoproteins, and also of phosphatidylinositol anchors. Glycobiology: A Practical Approach describes the essential analytical techniques required to study glycoproteins and will be an important practical guide for all researchers, including those in the pharmaceutical industry, working in this field.
Book Synopsis Handbook of Glycomics by : Richard D. Cummings
Download or read book Handbook of Glycomics written by Richard D. Cummings and published by Academic Press. This book was released on 2009-09-15 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Written for a range of readers from glycobiology investigators to researchers and students in genomics, proteomics, systems biology, bioinformatics and novel therapeutics, this handbook defines why all complex carbohydrates in organisms need to be studied. It begins by describing analytic approaches and bioinformatics, and moves on to provide a detailed discussion of relevant databases, data integration, and analysis. A discussion of various model organisms and pathogen glycomes is then followed by detail on therapeutic approaches to human disorders of glycosylation. Structure and function of glycomes are included along with state-of-the-art technologies and systems approaches to the analysis of glycans." --Book Jacket.
Book Synopsis Comprehensive Glycoscience by : G.-J. Boons
Download or read book Comprehensive Glycoscience written by G.-J. Boons and published by Elsevier Science. This book was released on 2007-08-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrates are an important part of life and are present in bacteria, fungi, viruses, yeast, plants, animals and humans. The rapid expansion of chemistry and glycobiology over the last few years has provided many new, imaginative and efficient techniques which provide further insight into the structures and biological interactions of carbohydrates and glycostructures. Comprehensive Glycoscience has a very broad scope and will appeal to a wide audience as it explores the interactions between biology, chemistry and molecular biology towards understanding, synthesising and developing glycoproteins, glycolipids, proteoglyans and polysaccharides, which are important molecules in nature for controlling health and disease and food and feed. Glycocompounds reviewed include: oligosaccharides, polysaccharides, glycoproteins, glycolipids, glycoconjugates, lectins, cellulose, pectins and starch. Topics covered include: spectroscopy, nomenclature, structures, synthesis, biosynthesis, molecular interactions, degradation, biochemistry, glycobiology, glycotherapeutics and diseases.
Book Synopsis Carbohydrate Recognition by : Binghe Wang
Download or read book Carbohydrate Recognition written by Binghe Wang and published by John Wiley & Sons. This book was released on 2011-09-09 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.
Book Synopsis The Art of Carbohydrate Analysis by : Gerrit J. Gerwig
Download or read book The Art of Carbohydrate Analysis written by Gerrit J. Gerwig and published by Springer Nature. This book was released on 2021-10-23 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing importance of glycobiology and carbohydrate chemistry in modern biotechnology and the pharmaceutical industry makes accurate carbohydrate analysis indispensable. This book provides the principles and protocols of various fundamental carbohydrate analysis methods. Choice of method is entirely dependent upon the type of material being investigated (biological samples, food products, etc.), and the level of structural detail required, i.e. sugar content, compositional analysis, linkages between the sugar components, or the total chemical structure of a given molecule. Full structural characterization of carbohydrate chains requires significant time, resources, and skill in several methods of analysis; no single technique can address all glycan analysis needs. This book summarizes several existing analytical techniques (both chemical and physical) in an introductory volume designed for the non-expert researcher or novice scientist. While background in carbohydrate chemistry is assumed, all information necessary to understanding the described techniques is addressed in the text.
