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Planaria A Model For Drug Action And Abuse
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Book Synopsis Planaria: A Model for Drug Action and Abuse by : Robert B. Raffa
Download or read book Planaria: A Model for Drug Action and Abuse written by Robert B. Raffa and published by CRC Press. This book was released on 2008-12-03 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of drug action has benefitted greatly from the development and use of in vivo model systems. In model systems, manipulations and observations can be more rigorously controlled and screens of novel therapeutic agents can be more safely conducted.No single model system provides all of the possible advantages. At one end, mammalian models al
Download or read book The First Brain written by Oné R. Pagán and published by Oxford University Press. This book was released on 2014-03-18 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Planarians, a class of flatworm, are extraordinary: they possess the remarkable ability to regenerate lost body parts, including complete regeneration of the nervous system. If cut into pieces, each piece of the planarian can regenerate into a complete organism. They are also unique among invertebrates in that they display addiction-like behaviors to many drugs abused by humans. Because of these distinct neurological traits, the planarian is often used as an animal model in neurological research, being used most recently for developments in neuropharmacology. The First Brain is a discussion of how planarians have been used in neuropharmacology, and what role they have played in scientific developments that have a high impact on our culture. Planarians have been the animal models for research in drug addiction, antidepressant development, and various other topics in biology, neurobiology, and even zoology. Pagán uses these flatworms as a framework to explore the history of biological research. The book provides accessible background information on how biomedical research is impacted by evolution, and defines neurobiology and neuropharmacology in ways that are easy to understand. At the same time, Pagán provides enough detail for the book to useful for scientists working in various subsections of biology. The planarian has played a key role in the history biological, neuropharmacological, and zoological research, and has even made appearances in a few unexpected places in popular culture. Oné Pagán explores all these roles, and shows us why the planarian truly is one of the most extraordinary and influential organisms in scientific research today.
Book Synopsis Invertebrate Medicine by : Gregory A. Lewbart
Download or read book Invertebrate Medicine written by Gregory A. Lewbart and published by John Wiley & Sons. This book was released on 2022-04-19 with total page 757 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presented in full color for the first time, Invertebrate Medicine is the definitive resource on husbandry and veterinary medicine in invertebrate species. Presenting authoritative information applicable to both in-human care and wild invertebrates, this comprehensive volume addresses the medical care and clinical condition of most important invertebrate species—providing biological data for sponges, jellyfish, anemones, snails, sea hares, corals, cuttlefish, squid, octopuses, clams, oysters, crabs, crayfish, lobsters, shrimp, hermit crabs, spiders, scorpions, horseshoe crabs, honey bees, butterflies, beetles, sea stars, sea urchins, sea cucumbers, various worms, and many other invertebrate groups. The extensively revised third edition contains new information and knowledge throughout, offering timely coverage of significant advances in invertebrate anesthesia, analgesia, diagnostic imaging, surgery, and welfare. New and updated chapters incorporate recent publications on species including crustaceans, jellyfishes, corals, honeybees, and a state-of-the-science formulary. In this edition, the authors also discuss a range of topics relevant to invertebrate caretaking including conservation, laws and regulations, euthanasia, diagnostic techniques, and sample handling. Edited by a leading veterinarian and expert in the field, Invertebrate Medicine, Third Edition: Provides a comprehensive reference to all aspects of invertebrate medicine Offers approximately 200 new pages of expanded content Features more than 400 full color images and new contributions from leading veterinarians and specialists for each taxon Includes updated chapters of reportable diseases, neoplasia, sources of invertebrates and supplies, and a comprehensive formulary The standard reference text in the field, Invertebrate Medicine, Third Edition is essential reading for practicing veterinarians, veterinary students, advanced hobbyists, aquarists and aquaculturists, and professional animal caretakers in zoo animal, exotic animal, and laboratory animal medicine.
Book Synopsis Alternative Methods in Neurotoxicology by :
Download or read book Alternative Methods in Neurotoxicology written by and published by Elsevier. This book was released on 2023-06-08 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alternative Methods in Neurotoxicology, Volume Nine, the latest release in this series, provides an overview of important in vitro and non-vertebrate animal models available to study the neurotoxicity of a range of toxicants of occupational and environmental relevance. Chapters in this new release include Evaluation of mitochondrial function in neurotoxicology using alternative models, Planarians as a model to study neurotoxic agents, Role of Drosophila melanogaster in neurotoxicology studies: Responses to different harmful substances, Neurotoxicology of metals and metallic nanoparticles in Caenorhabditis elegans, Neurotoxicology of environmental toxicants using Caenorhabditis elegans as a model, Nauphoeta cinerea as an emerging model in neurotoxicology, and more. Other chapters cover Human Neural Stem Cells in Developmental Neurotoxicology: Current Scenario and Future Prospects, Use of Drosophila melanogaster for advances in developmental neurotoxicology studies, 3D neurospheres and neurotoxicity of organophosphorus and TCE, Genetic factors in methylmercury-induced neurotoxicity: what we have learned from Caenorhabditis elegans models, and more. Give an up-to-date about the utilization of popular invertebrates (Drosophila melanogaster and Caenorhabditis elegans) in neurotoxicology Brings concise information on emerging invertebrate models in neurotoxicology (from basic to environmental approaches) Presents updates on the in vitro exploitation of human stem cell in developmental neurotoxicology
Book Synopsis Neural Stem Cells and Therapy by : Tao Sun
Download or read book Neural Stem Cells and Therapy written by Tao Sun and published by BoD – Books on Demand. This book was released on 2012-02-15 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collective work of international experts in the neural stem cell field. The book incorporates the characterization of embryonic and adult neural stem cells in both invertebrates and vertebrates. It highlights the history and the most advanced discoveries in neural stem cells, and summarizes the mechanisms of neural stem cell development. In particular, this book provides strategies and discusses the challenges of utilizing neural stem cells for therapy of neurological disorders and brain and spinal cord injuries. It is suitable for general readers, students, doctors and researchers who are interested in understanding the principles of and new discoveries in neural stem cells and therapy.
Book Synopsis Epigenetic Mechanisms of the Cambrian Explosion by : Nelson R Cabej
Download or read book Epigenetic Mechanisms of the Cambrian Explosion written by Nelson R Cabej and published by Academic Press. This book was released on 2019-10-12 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic Mechanisms of the Cambrian Explosion provides readers with a basic biological knowledge and epigenetic explanation of the biological puzzle of the Cambrian explosion, the unprecedented rapid diversification of animals that began 542 million years ago. During an evolutionarily instant of ~10 million years, which represents only 0.3% of the time of existence of life on Earth, or less than 2% of the time of existence of metazoans, all of the 30 extant body plans, major animal groups (phyla) and several extinct groups appeared. The work helps address this phenomena and tries to answer remaining questions for evolutionary biology, epigenetics, and scientific researchers. The book recognizes and presents objective representations of alternative theories for epigenetic evolution in this period, with the author drawing on his epigenetic theory of evolution to explain the causal basis of the Cambrian explosion. Both empirical evidence and theoretical arguments are presented in support of this thought-provoking epigenetic theory. Explains the Cambrian explosion from an entirely epigenetic view Takes a causal rather than descriptive approach to the phenomenon Allows for a broad readership, including those with only a basic biological knowledge, while maintaining scientific rigor
Book Synopsis The Evolution of the Sensitive Soul by : Simona Ginsburg
Download or read book The Evolution of the Sensitive Soul written by Simona Ginsburg and published by MIT Press. This book was released on 2019-03-12 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new theory about the origins of consciousness that finds learning to be the driving force in the evolutionary transition to basic consciousness. What marked the evolutionary transition from organisms that lacked consciousness to those with consciousness—to minimal subjective experiencing, or, as Aristotle described it, “the sensitive soul”? In this book, Simona Ginsburg and Eva Jablonka propose a new theory about the origin of consciousness that finds learning to be the driving force in the transition to basic consciousness. Using a methodology similar to that used by scientists when they identified the transition from non-life to life, Ginsburg and Jablonka suggest a set of criteria, identify a marker for the transition to minimal consciousness, and explore the far-reaching biological, psychological, and philosophical implications. After presenting the historical, neurobiological, and philosophical foundations of their analysis, Ginsburg and Jablonka propose that the evolutionary marker of basic or minimal consciousness is a complex form of associative learning, which they term unlimited associative learning (UAL). UAL enables an organism to ascribe motivational value to a novel, compound, non-reflex-inducing stimulus or action, and use it as the basis for future learning. Associative learning, Ginsburg and Jablonka argue, drove the Cambrian explosion and its massive diversification of organisms. Finally, Ginsburg and Jablonka propose symbolic language as a similar type of marker for the evolutionary transition to human rationality—to Aristotle's “rational soul.”
Download or read book Emerging Model Organisms written by and published by . This book was released on 2009 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume leading experts provide chapters on 23 emerging model systems, ranging from bat and butterfly to cave fish and choanoflagellates; cricket and finch to quail, snail, and tomato.
Book Synopsis Environmental Literacy in Science and Society by : Roland W. Scholz
Download or read book Environmental Literacy in Science and Society written by Roland W. Scholz and published by Cambridge University Press. This book was released on 2011-07-21 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: In an era where humans affect virtually all of the earth's processes, questions arise about whether we have sufficient knowledge of human-environment interactions. How can we sustain the Earth's ecosystems to prevent collapses and what roles should practitioners and scientists play in this process? These are the issues central to the concept of environmental literacy. This unique book provides a comprehensive review and analysis of environmental literacy within the context of environmental science and sustainable development. Approaching the topic from multiple perspectives, it explores the development of human understanding of the environment and human-environment interactions in the fields of biology, psychology, sociology, economics and industrial ecology. The discussion emphasises the importance of knowledge integration and transdisciplinary processes as key strategies for understanding complex human-environment systems (HES). In addition, the author defines the HES framework as a template for investigating sustainably coupled human-environment systems in the 21st century.
Book Synopsis Planarian Regeneration by : Jochen C. Rink
Download or read book Planarian Regeneration written by Jochen C. Rink and published by Humana. This book was released on 2018-06-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the various facets of planaria as a biomedical model system and discusses techniques used to study the fascinating biology of these animals. The chapters in this book are divided into two parts: Part One looks at the biodiversity of planarian species, the molecular orchestration of regeneration, ecology of planarians in their natural habitats and their history as lab models. Part Two talks about experimental protocols for studying planarians, ranging from the establishment of a planarian research colony, to RNA and DNA extraction techniques, all the way to single stem cell transplantations or metabolomics analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Planarian Regeneration: Methods and Protocols is a valuable resource for both newcomers to the field and experts within established planarian laboratories.
Book Synopsis International Handbook of Psychology Learning and Teaching by : Joerg Zumbach
Download or read book International Handbook of Psychology Learning and Teaching written by Joerg Zumbach and published by Springer Nature. This book was released on 2022-12-16 with total page 1483 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Handbook of Psychology Learning and Teaching is a reference work for psychology learning and teaching worldwide that takes a multi-faceted approach and includes national, international, and intercultural perspectives. Whether readers are interested in the basics of how and what to teach, in training psychology teachers, in taking steps to improve their own teaching, or in planning or implementing research on psychology learning and teaching, this handbook will provide an excellent place to start. Chapters address ideas, issues, and innovations in the teaching of all psychology courses, whether offered in psychology programs or as part of curricula in other disciplines. The book also presents reviews of relevant literature and best practices related to everything from the basics of course organization to the use of teaching technology. Three major sections consisting of several chapters each address “Teaching Psychology in Tertiary (Higher) Education”, “Psychology Learning and Teaching for All Audiences”, and “General Educational and Instructional Approaches to Psychology Learning and Teaching”.
Download or read book Sigma, PCP, and NMDA Receptors written by and published by . This book was released on 1993 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Roy Adaptation Model in Action by : Justus Akinsanya
Download or read book The Roy Adaptation Model in Action written by Justus Akinsanya and published by Red Globe Press. This book was released on 1994-05-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is part of the Nursing Models in Action Series, which provides in-depth theory and practical applications of the major nursing models. Roys Model allows nurses to examine both physiological and psychosocial issues related to the patients and their care. By confronting the way that individuals react to stress, nurses using Roys Model can achieve a holistic assessment and resulting quality of care. This book will provide the reader with a clear, easily understood review of the adaptation model and its application in practice. The authors of this book are all experienced teachers, who provide invaluable information on how to overcome conceptual and practical problems in the use of the model, using examples from their clinical experiences.
Book Synopsis Drug Delivery Systems by : Stroeve Pieter
Download or read book Drug Delivery Systems written by Stroeve Pieter and published by World Scientific. This book was released on 2017-11-27 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the alarming increase in cancer diagnoses and genetic illnesses, traditional drug agents and their delivery media need to be re-evaluated to address a quickly evolving field. With newer smart materials for the controlled release of macromolecules, peptides, genetic material, etc. further complications arise, such as material performance, synthesis, functionalization and targeting, biological identity, and biocompatibility. The book provides a comprehensive overview of the recent developments on "smart" targeting and drug delivery systems with a variety of carriers like nanoparticles, membranes, and hydrogels. It contains detailed descriptions on the recent trends in this field in the ongoing battle with catastrophic diseases like cancer. This field of research has been in its infancy and continues to face growth, and with it, further challenges and difficulties along the way toward maturity, which are accurately introduced in this book. Contents: Drug Delivery Systems: Possibilities and Challenges (Ryan Spitler, Saeid Zanganeh, Tahereh Jafari, Nasser Khakpash, Mohsen Erfanzadeh, Jim Q Ho, and Nastaran Sakhaie)Nanoparticles in Circulation: Blood Stability (Saeid Zanganeh, Tahereh Jafari, Nasser Khakpash, Mohsen Erfanzadeh, and Jim Q Ho)How do Nanoparticles (NPs) Pass Barriers? (Saeid Zanganeh, Ryan Spitler, Najme Javdani, and Jim Q Ho)Gated Porous Materials for Biomedical Application (Félix Sancenón, Erick Yu, Elena Aznar, M Dolores Marcos, and Ramón Martínez-Máñez)Controlled Release from Iron Oxide Nanoparticles (Masoud Rahman)The Reverse of Controlled Release: Controlled Sequestration of Species and Biotoxins into Nanoparticles (NPs) (Jenifer Gómez-Pastora, Eugenio Bringas, María Lázaro-Díez, José Ramos-Vivas, and Inmaculada Ortiz)Membranes for Controlled Release (Vida Araban, Neda Aslankoohi, and Mohammad Raoufi)Controlled Released from Hydrogel (Hossein Riahinezhad, Vida Araban, and Mohammad Raoufi)Nano Delivery Systems (Sophie Laurent, Afsaneh Lahooti, Saeed Shanehsazzadeh, and Robert N Muller)Legal Framework for Protection of Pharmaceutical Trade Marks in Europe and USA (Mohammad Hossein Erfanmanesh, and Shirin Sharifzadeh)Future Perspective on the Smart Delivery of Biomolecules (Erick Yu, Félix Sancenón, Elena Aznar, Ramón Martínez-Máñez, María Dolores Marcos, Mohammad J Hajipour, Morteza Mahmoudi, and Pieter Stroeve) Readership: Nanotechnologists; biomedical engineers; chemical engineers; materials scientists; biotechnology researchers; chemists; biological scientists; cell physiologists; medical scientists; gene therapists. Keywords: Drug Delivery Systems;Nanoparticles;Biomaterials;TargetingReview: Key Features: Comprehensive overview on "smart" targeting and drug delivery systemsUnderstanding of the biological identity of nanoparticles for drug delivery applicationsDetailed information on the legal framework for protection of pharmaceutical trade mark in Europe and the United States
Book Synopsis Alternatives to Animal Use in Research, Testing, and Education by :
Download or read book Alternatives to Animal Use in Research, Testing, and Education written by and published by . This book was released on 1986 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Meningitis and Encephalitis by : Rodrigo Hasbun
Download or read book Meningitis and Encephalitis written by Rodrigo Hasbun and published by Springer. This book was released on 2018-07-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae. The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs, overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportion of unknown etiologies, low sensitivity of current microbiological techniques especially in the setting of previous antibiotic therapy, underutilization of available molecular diagnostic tests, and empiric antibiotic therapy and hospitalization for viral meningitis cases. Even though there are published guidelines, compliance with them is not optimal and physicians do not follow standardized algorithms in their empirical approach. As meningitis and encephalitis is associated with high rates of adverse clinical outcomes, prevention, when feasible is of upmost importance. Adherence to protocols to prevent health-care associated meningitis and ventriculitis are effective but compliance with them is not uniformly performed. This book seeks to improve outcomes for meningitis and encephalitis cases handled by physicians who may or may not be thoroughly trained for these challenges. The text introduces the current guidelines but also discusses the gaps that leave clinicians struggling to implement the most appropriate approaches for these particular neurological infections. Each chapter delivers the tools necessary to identify and adhere to the most appropriate diagnostic technique, management protocols, and prevention approach for each situation. All chapters conclude with discourse on future directions in research and quality improvement. Written by experts in infectious diseases, the book covers topics that are the most devastating, including healthcare-acquired infections, autoimmune encephalitis, and infections as they present in HIV patients. Meningitis and Encephalitis is a well-rounded resource for all medical professionals encountering these neurological syndromes, including infectious disease specialists, neurologists, primary care physicians, and immunologists.
Book Synopsis The Chemical Industry in Europe, 1850–1914 by : Ernst Homburg
Download or read book The Chemical Industry in Europe, 1850–1914 written by Ernst Homburg and published by Springer Science & Business Media. This book was released on 1998-10-31 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Europe is the cradle of the modem international chemical industry. From the middle of the nineteenth century until the outbreak of World War I, the European chemical industry influenced not only the production and control of science and technology, but also made significant contributions towards economic development, as well as bringing about profound changes in working and living enviromnents. It is a highly complex heritage, both rich and threatening, that calls for close scrutinity. Fortunately, a unique opportunity to explore the historical development of the European chemical industry from a variety of novel standpoints, was made possible during 1993 as part of the European Science Foundation (ESF) programme called 'The Evolution of Chemistry in Europe, 1789-1939.' This process of exploration has taken place through three workshops, each dealing with different time periods. The workshop concerned with the period 1850-1914, which corresponds roughly to the so-called Second Industrial Revolution, was held in Maastricht, The Netherlands, on 23-25 March 1995. This volume is the outcome of that workshop. The other workshops dealing with European chemical industry were held in Liege in 1994, covering the First Industrial Revolution period, 1789-1850, and Strasbourg in 1996, covering the period between the two World Wars.
