Glial Physiology and Pathophysiology

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780470978528
Total Pages : 0 pages
Book Rating : 4.9/5 (785 download)

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Book Synopsis Glial Physiology and Pathophysiology by : Alexei Verkhratsky

Download or read book Glial Physiology and Pathophysiology written by Alexei Verkhratsky and published by John Wiley & Sons. This book was released on 2013-04-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverage includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role of glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides

Glial Neurobiology

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Publisher : John Wiley & Sons
ISBN 13 : 9780470513071
Total Pages : 230 pages
Book Rating : 4.5/5 (13 download)

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Book Synopsis Glial Neurobiology by : Alexei Verkhratsky

Download or read book Glial Neurobiology written by Alexei Verkhratsky and published by John Wiley & Sons. This book was released on 2007-08-20 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This volume is a very valuable and much needed contribution." –Quarterly Review of Biology AT LAST - A comprehensive, accessible textbook on glial neurobiology! Glial cells are the most numerous cells in the human brain but for many years have attracted little scientific attention. Neurophysiologists concentrated their research efforts instead, on neurones and neuronal networks because it was thought that they were the key elements responsible for higher brain function. Recent advances, however, indicate this isn’t exactly the case. Not only are astroglial cells the stem elements from which neurones are born, but they also control the development, functional activity and death of neuronal circuits. These ground-breaking developments have revolutionized our understanding of the human brain and the complex interrelationship of glial and neuronal networks in health and disease. Features of this book: an accessible introduction to glial neurobiology including an overview of glial cell function and its active role in neural processes, brain function and nervous system pathology an exploration of all the major types of glial cells including: the astrocytes, oligodendrocytes and microglia of the ACNS and Schwann cells of the peripheral nervous system; the book also presents a broad overview of glial receptors and ion channels an investigation into the role of glial cells in various types of brain diseases including stroke, neurodegenerative diseases such as Alzheimer's, Parkinson's and Alexander's disease, brain oedema, multiple sclerosis and many more a wealth of illustrations, including unique images from the authors' own libraries of images, describing the main features of glial cells Written by two leading experts in the field, Glial Neurobiology provides a concise, authoritative introduction to glial physiology and pathology for undergraduate/postgraduate neuroscience, biomedical, medical, pharmacy, pharmacology, and neurology, neurosurgery and physiology students. It is also an invaluable resource for researchers in neuroscience, physiology, pharmacology and pharmaceutics.

Physiology and Pathology of Neuroglia

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832531482
Total Pages : 111 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Physiology and Pathology of Neuroglia by : Reyes-Haro

Download or read book Physiology and Pathology of Neuroglia written by Reyes-Haro and published by Frontiers Media SA. This book was released on 2023-08-07 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Enteric Glia

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Publisher : Biota Publishing
ISBN 13 : 1615046615
Total Pages : 72 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Enteric Glia by : Brian D. Gulbransen

Download or read book Enteric Glia written by Brian D. Gulbransen and published by Biota Publishing. This book was released on 2014-07-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography

Introduction to Neuroglia

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Publisher : Biota Publishing
ISBN 13 : 1615046496
Total Pages : 74 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Introduction to Neuroglia by : Alexei Verkhratsky

Download or read book Introduction to Neuroglia written by Alexei Verkhratsky and published by Biota Publishing. This book was released on 2014-02-01 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the introduction to a series of e-books dedicated to the physiology and pathophysiology of neuroglia. The topic of neuroglia is generally overlooked in neuroscience curricula across the world, the main attention being focused on the description of excitability of neurons and neuronal networks. The neuroglia, being electrically non-excitable, are universally regarded as supportive cells which do not contribute to information processing. This oversimplified view, however, ignores the tremendous importance of brain homeostasis, which is imperative for the ongoing activity of neuronal networks. It also ignores the truth that specialization of neurons and their ability for rapid propagation and multi-level integration of signals become possible only because of delegation of homeostatic abilities to neuroglia. Furthermore, glial cells contribute to information processing as they can modulate neuronal synaptic transmission. Finally, neuroglia provide the only system of brain defense and as such these cells are intimately involved in all types of neuropathologies, and contribute to both neuroprotection and regeneration of the nervous system. The e-books in this series provide a platform for in-depth learning of all aspects of neuroglial cells function in health and disease.

Astrocytes in (Patho)Physiology of the Nervous System

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Publisher : Springer Science & Business Media
ISBN 13 : 0387794921
Total Pages : 701 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Astrocytes in (Patho)Physiology of the Nervous System by : Vladimir Parpura

Download or read book Astrocytes in (Patho)Physiology of the Nervous System written by Vladimir Parpura and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Astrocytes were the original neuroglia that Ramón y Cajal visualized in 1913 using a gold sublimate stain. This stain targeted intermediate filaments that we now know consist mainly of glial fibrillary acidic protein, a protein used today as an astrocytic marker. Cajal described the morphological diversity of these cells with some ast- cytes surrounding neurons, while the others are intimately associated with vasculature. We start the book by discussing the heterogeneity of astrocytes using contemporary tools and by calling into question the assumption by classical neuroscience that neurons and glia are derived from distinct pools of progenitor cells. Astrocytes have long been neglected as active participants in intercellular communication and information processing in the central nervous system, in part due to their lack of electrical excitability. The follow up chapters review the “nuts and bolts” of ast- cytic physiology; astrocytes possess a diverse assortment of ion channels, neu- transmitter receptors, and transport mechanisms that enable the astrocytes to respond to many of the same signals that act on neurons. Since astrocytes can detect chemical transmitters that are released from neurons and can release their own extracellular signals there is an increasing awareness that they play physiological roles in regulating neuronal activity and synaptic transmission. In addition to these physiological roles, it is becoming increasingly recognized that astrocytes play critical roles during pathophysiological states of the nervous system; these states include gliomas, Alexander disease, and epilepsy to mention a few.

Anatomy and Physiology

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Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oligodendrocyte Physiology and Pathology Function

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Publisher : MDPI
ISBN 13 : 3039436899
Total Pages : 330 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Oligodendrocyte Physiology and Pathology Function by : Markus Kipp

Download or read book Oligodendrocyte Physiology and Pathology Function written by Markus Kipp and published by MDPI. This book was released on 2021-01-06 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adult vertebrate central nervous system mainly consists of neurons, astrocytes, microglia cells, and oligodendrocytes. Oligodendrocytes, the myelin-forming cells of the CNS, are subjected to cell stress and subsequent death in a number of metabolic or inflammatory disorders, among which multiple sclerosis (MS) is included. This disease is associated with the development of large demyelinated plaques, oligodendrocyte destruction, and axonal degeneration, paralleled by the activation of astrocytes and microglia as well as the recruitment of peripheral immune cells to the site of tissue injury. Of note, viable oligodendrocytes and an intact myelin sheath are indispensable for neuronal health. For example, it has been shown that oligodendrocytes provide nutritional support to neurons, fast axonal transport depends on proper oligodendrocyte function, and mice deficient in mature myelin proteins eventually display severe neurodegeneration. This Special Issue contains a collection of highly relevant primary research articles as well as review articles focusing on the development, physiology, and pathology of the oligodendrocyte–axon–myelin unit.

Brain Neurotrauma

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Publisher : CRC Press
ISBN 13 : 1466565993
Total Pages : 718 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy

Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Astrocyte

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Publisher : BoD – Books on Demand
ISBN 13 : 9535138855
Total Pages : 244 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Astrocyte by : Maria Teresa Gentile

Download or read book Astrocyte written by Maria Teresa Gentile and published by BoD – Books on Demand. This book was released on 2018-03-21 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: A team of authors from prestigious academic schools contributed to draw up a project that would give a detailed account of astrocyte's morphology and physiology, examining thoroughly all the astrocyte's types; giving an accurate description of their morphology, location, function in the brain; and illustrating their physiology and pathology in terms of dealing with neurons through "gliotransmitters," ionic channels, and membrane receptors expression. This book gives an overview of the crucial role of astrocytes in the physiology of the CNS and in the pathogenesis of several CNS disorders suggesting that the shift from a neurocentric view to one that incorporates astrocytes in disease models for drug discovery is a critical step in renewing drug development strategies to treat neurodegenerative diseases.

Neuroglia

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Publisher : Oxford University Press
ISBN 13 : 9780195152227
Total Pages : 630 pages
Book Rating : 4.1/5 (522 download)

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Book Synopsis Neuroglia by : Helmut Kettenmann

Download or read book Neuroglia written by Helmut Kettenmann and published by Oxford University Press. This book was released on 2005 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Graduate students in neuroanatomy, neurochemistry, neurophysiology, and molecular neurobiology will find the book indispensable. It is also a vital companion for researchers in these fields as well as clinicians in neurology, neurosurgery, neuropathology, neuro-oncology, physiatry, and psychiatry."--BOOK JACKET.

Basic Physiology for Anaesthetists

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Publisher : Cambridge University Press
ISBN 13 : 1108463991
Total Pages : 469 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Basic Physiology for Anaesthetists by : David Chambers

Download or read book Basic Physiology for Anaesthetists written by David Chambers and published by Cambridge University Press. This book was released on 2019-07-25 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.

A Textbook of Neuroanatomy

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Publisher : John Wiley & Sons
ISBN 13 : 1118677358
Total Pages : 544 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis A Textbook of Neuroanatomy by : Maria A. Patestas

Download or read book A Textbook of Neuroanatomy written by Maria A. Patestas and published by John Wiley & Sons. This book was released on 2016-02-17 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Newly revised and updated, A Textbook of Neuroanatomy, Second Edition is a concise text designed to help students easily master the anatomy and basic physiology of the nervous system. Accessible and clear, the book highlights interrelationships between systems, structures, and the rest of the body as the chapters move through the various regions of the brain. Building on the solid foundation of the first edition, A Textbook of Neuroanatomy now includes two new chapters on the brainstem and reflexes, as well as dozens of new micrographs illustrating key structures. Throughout the book the clinical relevance of the material is emphasized through clinical cases, questions, and follow-up discussions in each chapter, motivating students to learn the information. A companion website is also available, featuring study aids and artwork from the book as PowerPoint slides. A Textbook of Neuroanatomy, Second Edition is an invaluable resource for students of general, clinical and behavioral neuroscience and neuroanatomy.

Neuroglia: Function and Pathology

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Publisher : Elsevier
ISBN 13 : 0128215666
Total Pages : 732 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Neuroglia: Function and Pathology by : Alexej Verkhratsky

Download or read book Neuroglia: Function and Pathology written by Alexej Verkhratsky and published by Elsevier. This book was released on 2023-05-12 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diverse specialised neuroglial cells guarantee the development, preservation, and health of the central nervous system, the peripheral nervous system, the enteric nervous system, and the special senses. In the central nervous system, it is the astrocytes, oligodendrocytes, and microglia that safeguard nerve cell function and integrity that controls all behaviours and encompasses the cerebral cortex of the brain which is the root of humanity. In the peripheral nervous system, Schwann cells play the leading role, together with satellite glial cells of the sensory and autonomic ganglia, ensuring correct communication between the organs and tissues with the brain and the spinal cord. In the enteric nervous system, specialised enteric glial cells maintain all aspects of gastrointestinal function. Then there are distinctive glial cells of the special senses that ensure how the body perceives and reacts to its environment. In pathology, neuroglia strive to protect the diverse cellular components of the nervous system and are responsible for a proactive programme of posttraumatic restructuring that is aimed at recovery of life-sustaining function. Neuroglia: Function and Pathology provides a highly original and comprehensive account of the physiology and pathophysiology of glial cells in the central and peripheral nervous systems. The first part of the book provides a far-reaching description of glial cell form and function, from their evolution in invertebrates to their complexity in humans, encompassing the developmental origin of the varied glial cell types and their diversity of morphology, molecular biology and cellular physiology. The second part of the book is devoted to an all-embracing evaluation of glial cell pathophysiology, commencing with definitive explanations of the fundamental pathologies of the main glial cell types, and ending in a systematic examination of glial contributions to specific neurological diseases. This book emphasises the central roles played by the different classes of neuroglial cells in the progression and outcome of neurological disorders of the central and peripheral nervous systems and highlights potential of glial cells as therapeutic targets. The book contains more than 2500 key references from over 150 years of glial research and is superbly illustrated with over 350 original and explanatory full colour figures that describe the diverse characteristics and properties of glial cells in health and disease. Under the same cover, this book combines an authoritative reference book for research and clinical neuroscientists and at the same time serves as an instructive textbook for students of neuroscience, from undergraduates to postgraduates. - Single volume covering key aspects of glial cell physiology and pathology - In depth overview of the history of glial cell research - Comprehensive review of glial cell physiology and pathology - Authoritative special chapters on the major neurological diseases - Full colour throughout, with 360 illustrations

Fundamental Neuroscience

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Publisher : Academic Press
ISBN 13 : 0080561020
Total Pages : 1277 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Fundamental Neuroscience by : Larry Squire

Download or read book Fundamental Neuroscience written by Larry Squire and published by Academic Press. This book was released on 2008-04-02 with total page 1277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental Neuroscience, Third Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts.Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers! 30% new material including new chapters on Dendritic Development and Spine Morphogenesis, Chemical Senses, Cerebellum, Eye Movements, Circadian Timing, Sleep and Dreaming, and Consciousness Additional text boxes describing key experiments, disorders, methods, and concepts Multiple model system coverage beyond rats, mice, and monkeys Extensively expanded index for easier referencing

Jubb, Kennedy & Palmer's Pathology of Domestic Animals: Volume 1

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Publisher : Elsevier Health Sciences
ISBN 13 : 070206842X
Total Pages : 1250 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Jubb, Kennedy & Palmer's Pathology of Domestic Animals: Volume 1 by : Grant Maxie

Download or read book Jubb, Kennedy & Palmer's Pathology of Domestic Animals: Volume 1 written by Grant Maxie and published by Elsevier Health Sciences. This book was released on 2015-08-16 with total page 1250 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an emphasis on the disease conditions of dogs, cats, horses, swine, cattle and small ruminants, Jubb, Kennedy, and Palmer's Pathology of Domestic Animals, 6th Edition continues its long tradition of being the most comprehensive reference book on common domestic mammal pathology. Using a body systems approach, veterinary pathology experts provide overviews of general system characteristics, reactions to insult, and disease conditions that are broken down by type of infectious or toxic insult affecting the anatomical subdivisions of each body system. The sixth edition now boasts a new full-color design, including more than 2,000 high-resolution images of normal and abnormal organs, tissues, and cells. Updated content also includes evolved coverage of disease agents such as the Schmallenberg virus, porcine epidemic diarrhea virus, and the porcine deltacoronavirus; plus new information on molecular-based testing, including polymerase chain reaction (PCR) and in-situ hybridization, keep you abreast of the latest diagnostic capabilities. - Updated content includes new and evolving pathogens and diagnostic techniques. - Updated bibliographies give readers new entry points into the rapidly expanding literature on each subject. - NEW! High-resolution color images clearly depict the diagnostic features of hundreds of conditions. - NEW! Introduction to the Diagnostic Process chapter illustrates the whole animal perspective and details the approaches to systemic, multi-system, and polymicrobial disease. - NEW! Coverage of camelids is now included in the reference's widened scope of species. - NEW! Team of 30+ expert contributors offers the latest perspective on the continuum of issues in veterinary pathology. - NEW! Expanded resources on the companion website include a variety of helpful tools such as full reference lists with entries linked to abstracts in Pub Med and bonus web-only figures. - NEW! Full-color design improves the accessibility of the text.

Conn's Translational Neuroscience

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Publisher : Academic Press
ISBN 13 : 0128025964
Total Pages : 778 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Conn's Translational Neuroscience by : P. Michael Conn

Download or read book Conn's Translational Neuroscience written by P. Michael Conn and published by Academic Press. This book was released on 2016-09-28 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conn's Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn's Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. - Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance - Features contributions from leading global basic and clinical investigators in the field - Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes - Relates and translates the current science to the understanding of neurological disorders and their treatment