Conns Translational Neuroscience

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Conn's Translational Neuroscience

Author : P. Michael Conn
Publisher : Academic Press
ISBN 13 : 0128025964
Total Pages : 776 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Conn's Translational Neuroscience by : P. Michael Conn

Download or read book Conn's Translational Neuroscience written by P. Michael Conn and published by Academic Press. This book was released on 2016-09-28 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conn’s Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn’s Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance Features contributions from leading global basic and clinical investigators in the field Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes Relates and translates the current science to the understanding of neurological disorders and their treatment

Translational Neuroscience

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis Translational Neuroscience by :

Download or read book Translational Neuroscience written by and published by . This book was released on with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Translational Neuroscience

Author : Karoly Nikolich
Publisher : MIT Press
ISBN 13 : 0262029863
Total Pages : 319 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Translational Neuroscience by : Karoly Nikolich

Download or read book Translational Neuroscience written by Karoly Nikolich and published by MIT Press. This book was released on 2015-08-21 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts from academia and industry discuss how to create a new, more effective translational neuroscience drawing on novel technology and recent discoveries. Today, translational neuroscience faces significant challenges. Available therapies to treat brain and nervous system disorders are extremely limited and dated, and further development has effectively ceased. Disinvestment by the private sector occurred just as promising new technologies in genomics, stem cell biology, and neuroscience emerged to offer new possibilities. In this volume, experts from both academia and industry discuss how novel technologies and reworked translation concepts can create a more effective translational neuroscience. The contributors consider such topics as using genomics and neuroscience for better diagnostics and biomarker identification; new approaches to disease based on stem cell technology and more careful use of animal models; and greater attention to human biology and what it will take to make new therapies available for clinical use. They conclude with a conceptual roadmap for an effective and credible translational neuroscience—one informed by a disease-focused knowledge base and clinical experience. Contributors Tobias M. Böckers, Thomas Bourgeron, Karl Broich, Nils Brose, Bruce N. Cuthbert, Ilka Diester, Gül Dölen, Guoping Feng, Richard Frackowiak, Raquel E. Gur, Stephan Heckers, Franz Hefti, David M. Holtzman, Steven E. Hyman, Nancy Ip, Cynthia Joyce, Tobias Kaiser, Edward H. Koo, Walter J. Koroshetz, Katja S. Kroker, Robert C. Malenka, Isabelle Mansuy, Eliezer, Masliah, Yuan Mei, Andreas Meyer-Lindenberg, Lennart Mucke, Pierluigi Nicotera, Karoly Nikolich, Michael J. Owen, Menelas N. Pangalos, Alvaro Pascual-Leone, Joel S. Perlmutter, Trevor W. Robbins, Lee L. Rubin, Akira Sawa, Mareike Schnaars, Bernd Sommer, Maria Grazia Spillantini, Laura Spinney, Matthew W. State, Marius Wernig

Electrophysiology and Microinjection

Author : P. Michael Conn
Publisher : Elsevier
ISBN 13 : 1483284891
Total Pages : 504 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Electrophysiology and Microinjection by : P. Michael Conn

Download or read book Electrophysiology and Microinjection written by P. Michael Conn and published by Elsevier. This book was released on 2016-07-02 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrical activity is central to the functioning and nature of neural cells. Every effort has been made in this volume to provide representative examples of useful techniques that have made this area a productive component of the neurosciences. Convenient bench-top format**Methods presented for easy adaptation to new systems**Comprehensive protocols included for**Cell recording: from conscious and freely behaving animals, measurement of calcium currents, and multiple electrodes**Voltage clamping and voltammetry: apparatus and applications**Specific ion channels and receptors: expression in oocytes, single-cell secretion, purification of calcium channel drug receptors**Special electrodes and other equipment: movable electrodes, microelectrodes, multiple electrodes, en passant recording, microincubators for optical studies**Special preparations: multicompartment cell cultures, grease-gap methods, perforated path techniques, giant proteoliposomes for reconstitution studies, microinjection**Data analysis and reduction: digital filtering on a personal computer, filtering on a personal computer, fitting of single-channel dwell time distributions, discrimination of kinetic models, voltage noise analysis, list-oriented analysis of single-channel systems

Receptors

Author : P. Michael Conn
Publisher : Academic Press
ISBN 13 : 1483259706
Total Pages : 456 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Receptors by : P. Michael Conn

Download or read book Receptors written by P. Michael Conn and published by Academic Press. This book was released on 2013-10-22 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques, and methods to determine receptor subclasses and localization in the ligand design. The first paper discusses the steroid receptor found in the central nervous system for steroid hormones that affects strongly the structure and function of both developed and immature nervous systems. Another paper describes how a glycoprotein of 79.5 kDa (transferrin) carries iron in the blood stream for delivery to different tissues, after the transferrin has bound with a specific receptor on the surface of the cell. This book also explains the binding sites of pituitary adenylate cyclase-activating polypeptide in the human brain, while one paper analyzes the neurotensin receptors during the primary culture of neurons. This volume then also analyzes the structure and function of the fast nerve growth factor receptor, particularly how a signal on the outside of a cell is transmitted to the cell's interior. This collection is helpful for microbiologists, cellular researchers, students, and professors in the discipline of neurosciences.

An Integrative Guide to Consumer Neuroscience

Author : Sven Braeutigam
Publisher : Oxford University Press
ISBN 13 : 019250729X
Total Pages : 304 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis An Integrative Guide to Consumer Neuroscience by : Sven Braeutigam

Download or read book An Integrative Guide to Consumer Neuroscience written by Sven Braeutigam and published by Oxford University Press. This book was released on 2022-03-16 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consumer neuroscience is a complex, interdisciplinary, and emerging field that cuts across psychology, neuroscience, and consumer research. The book provides a comprehensive overview of the foundations and applications of modern consumer neuroscience, exploring a wide range of established and emergent topics in the field, making it the ideal resource for anyone looking to broaden their knowledge base. The content provides a thorough, high-level guide to the mathematical, technological, and theoretical aspects of consumer neuroscience, alongside a wide range of specific applications situated within a scientific context. The book includes chapters on cognitive processes and behaviors, the human brain, mathematical concepts, and neuroscience technologies. It considers the difference of individual, social and commercial neuroscience through the lens of gender differences, aging and ethics, amongst other concepts, enabling the reader to adopt an holistic view of the field and discover new research directions. This is enhanced by the inclusion of consolidating questions and answers for each chapter alongside numerous images to enhance the reader's understanding of the topic. The book is an essential read for the aspiring researcher or practitioner striving for an in-depth understanding of the field and its ramifications.

Translational Neuroscience

Author : James Elmer Barrett
Publisher :
ISBN 13 : 9781139514804
Total Pages : 366 pages
Book Rating : 4.5/5 (148 download)

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Book Synopsis Translational Neuroscience by : James Elmer Barrett

Download or read book Translational Neuroscience written by James Elmer Barrett and published by . This book was released on 2012 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive analysis of translational neuroscience, covering all major areas of psychiatry, neurology and neurodevelopmental disorders.

Eight Key Brain Areas of Mental Health and Illness

Author : Jennifer Sweeton
Publisher : W. W. Norton & Company
ISBN 13 : 0393714144
Total Pages : 279 pages
Book Rating : 4.3/5 (937 download)

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Book Synopsis Eight Key Brain Areas of Mental Health and Illness by : Jennifer Sweeton

Download or read book Eight Key Brain Areas of Mental Health and Illness written by Jennifer Sweeton and published by W. W. Norton & Company. This book was released on 2021-11-30 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between neuroscience and clinical therapy. In this handbook, clinical psychologist and bestselling author Jennifer Sweeton details the eight main areas of the brain affected by mental illness, how brain changes show up in the therapy room as symptoms and behaviors, and the types of therapies and psychotherapeutic techniques research has shown can heal the brain. Areas covered are the thalamus, amygdala, hippocampus, insula, nucleus accumbens, anterior cingulate, ventromedial prefrontal cortex, and dorsolateral prefrontal cortex. No longer will you need to feel unsure when referencing basic brain functions related to behavioral health. After reading this book, you will feel confident and excited about your ability to take a client-centered, strategic, brain-based approach to treatment planning. Chapter summaries and tables of brain region, mental health condition, and therapeutic approach are included for easy reference.

The American Society of Addiction Medicine Handbook on Pain and Addiction

Author : Ilene Robeck
Publisher : Oxford University Press
ISBN 13 : 0190265388
Total Pages : 352 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis The American Society of Addiction Medicine Handbook on Pain and Addiction by : Ilene Robeck

Download or read book The American Society of Addiction Medicine Handbook on Pain and Addiction written by Ilene Robeck and published by Oxford University Press. This book was released on 2018-03-15 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Society of Addiction Medicine Handbook on Pain and Addiction provides clinical considerations and guidelines for the clinician treating patients with pain and addiction. Produced by the largest medical society dedicated to the improvement of addiction care, the book takes an evidence-based approach and uses articles from both the literature and well-regarded organizations and government agencies including NIDA, CDC, SAMHSA, PCSS-O, and ASAM itself. The ASAM Handbook is structured in five sections that cover the core concepts of addressing pain and addiction; diagnosis and treatment; treating pain in patients with, or at risk for, co-occuring addiction; treating substance use disorders (SUD) and addiction in patients with co-occuring pain; and adapting treatment to the needs of specific populations. Each chapter ends with suggestions for further reading on the topics discussed. This book is ideal for primary care providers, mental health clinicians, SUD clinicians, and pain clinicians who wish to bridge the knowledge gaps related to treating patients with pain and addiction. To learn more about the American Society of Addiction Medicine, and its commitment to providing the best resources for addiction clinicians, please visit http://www.asam.org.

Praxis As a Perspective on International Politics

Author : Gunther Hellmann
Publisher : Policy Press
ISBN 13 : 1529220475
Total Pages : 320 pages
Book Rating : 4.5/5 (292 download)

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Book Synopsis Praxis As a Perspective on International Politics by : Gunther Hellmann

Download or read book Praxis As a Perspective on International Politics written by Gunther Hellmann and published by Policy Press. This book was released on 2023-10 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together leading figures in the study of international relations, this collection explores praxis as a perspective on international politics and law. It builds on the transdisciplinary work of Friedrich Kratochwil to reveal the scope, limits and blind spots of praxis theorizing.

Translational Neuroscience

Author : James E. Barrett
Publisher : Cambridge University Press
ISBN 13 : 1139510304
Total Pages : pages
Book Rating : 4.1/5 (395 download)

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Book Synopsis Translational Neuroscience by : James E. Barrett

Download or read book Translational Neuroscience written by James E. Barrett and published by Cambridge University Press. This book was released on 2012-06-28 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational neuroscience is at the heart of clinical advancement in the fields of psychiatry, neurology and neurodevelopmental disorders. Written and edited by leading scientists and clinicians, this is a comprehensive and authoritative analysis of this emerging strategy for developing more effective treatments for brain disorders. Introductory chapters bring together perspectives from both academia and industry, while subsequent sections focus on disease groups, including bipolar disorder and depression, attention deficit hyperactivity disorder, substance abuse, autism, Alzheimer's disease, pain, epilepsy, Parkinson's disease and multiple sclerosis. Each section includes topical introductory and summary chapters, providing an overview and synthesis of the field. Translational Neuroscience: Applications in Psychiatry, Neurology, and Neurodevelopmental Disorders is an important text for clinicians, scientists and students in academic settings, government agencies and industry, as well as those working in the fields of public health and the behavioural sciences.

Nanocarriers for Drug-Targeting Brain Tumors

Author : Lalit Kumar
Publisher : Elsevier
ISBN 13 : 0323914713
Total Pages : 864 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Nanocarriers for Drug-Targeting Brain Tumors by : Lalit Kumar

Download or read book Nanocarriers for Drug-Targeting Brain Tumors written by Lalit Kumar and published by Elsevier. This book was released on 2022-06-21 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems. Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting. Provides information on the design and development of nanocarriers for targeting brain tumors Outlines the working principles of different nanocarriers for targeting brain tumors Includes case studies of different nanocarriers for targeting brain tumors

Standard Methods for Thermal Comfort Assessment of Clothing

Author : Ivana Špelić
Publisher : CRC Press
ISBN 13 : 042975065X
Total Pages : 228 pages
Book Rating : 4.4/5 (297 download)

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Book Synopsis Standard Methods for Thermal Comfort Assessment of Clothing by : Ivana Špelić

Download or read book Standard Methods for Thermal Comfort Assessment of Clothing written by Ivana Špelić and published by CRC Press. This book was released on 2019-06-20 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing detailed analysis of the thermal comfort assessment of clothing as the basis for developing standards, this book discusses the thermal protective role of clothing as a way of modelling heat transfer from the body, general thermal regulation of humans, and the importance of globally accepted test methods and standards to improve quality. New materials and discoveries in the study of thermal comfort necessitate the need for standard improvements and update. The development of international standards and the unification of testing methods is of crucial significance to ensure cost reduction and health protection. The book promotes instruments, methods, implementation of unified specifications, and the definition of standards so that a clear quality management system can be established, for both production systems and testing methods. It discusses standards in ergonomics of the thermal environment, clothing thermal characteristics, and subjective assessment of thermal comfort, which allows for systematic control of the measuring methods and the services and final products that are distributed on the global market. This book is aimed at industry professionals, researchers, and advanced students working in textile and clothing engineering, comfort testing, and ergonomics.

The Temporal Lobe

Author :
Publisher : Elsevier
ISBN 13 : 0128234946
Total Pages : 582 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis The Temporal Lobe by :

Download or read book The Temporal Lobe written by and published by Elsevier. This book was released on 2022-08-12 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Temporal Lobe, Volume 187 covers the exponential growth of studies on the relationships between brain and language/cognition, many of which involved the temporal lobe. This volume summarizes research on the anatomy and function of the temporal lobe under both normal and pathological conditions. In addition, it discusses the interactions of the temporal lobe with other brain structures. The book highlights the role of the temporal lobe in language processing as well as vision, object, face recognition and processing. The book also discusses the temporal lobe's role in reading, speech and the processing of color, music, action and memory. Temporal lobe disorders, assessments and treatments are also covered, including encephalitis, Alzheimer’s, epilepsy, Korsakov’s syndrome, and more. Summarizes research on the anatomy and function of the temporal lobe Identifies the importance of the temporal lobe to language and speech Includes how the temporal lobe interacts with other brain structures Reviews disorders of the temporal lobe, including dementia, encephalitis, and more

Mechanism and Genetic Susceptibility of Neurological Disorders

Author : Andleeb Khan
Publisher : Springer Nature
ISBN 13 : 9819994047
Total Pages : 425 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Mechanism and Genetic Susceptibility of Neurological Disorders by : Andleeb Khan

Download or read book Mechanism and Genetic Susceptibility of Neurological Disorders written by Andleeb Khan and published by Springer Nature. This book was released on with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design, User Experience, and Usability. Design Philosophy and Theory

Author : Aaron Marcus
Publisher : Springer
ISBN 13 : 303023570X
Total Pages : 608 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Design, User Experience, and Usability. Design Philosophy and Theory by : Aaron Marcus

Download or read book Design, User Experience, and Usability. Design Philosophy and Theory written by Aaron Marcus and published by Springer. This book was released on 2019-07-10 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: The four-volume set LNCS 11583, 11584, 11585, and 11586 constitutes the proceedings of the 8th International Conference on Design, User Experience, and Usability, DUXU 2019, held as part of the 21st International Conference, HCI International 2019, which took place in Orlando, FL, USA, in July 2019. The total of 1274 papers and 209 posters included in the 35 HCII 2019 proceedings volumes was carefully reviewed and selected from 5029 submissions. DUXU 2019 includes a total of 167 regular papers, organized in the following topical sections: design philosophy; design theories, methods, and tools; user requirements, preferences emotions and personality; visual DUXU; DUXU for novel interaction techniques and devices; DUXU and robots; DUXU for AI and AI for DUXU; dialogue, narrative, storytelling; DUXU for automated driving, transport, sustainability and smart cities; DUXU for cultural heritage; DUXU for well-being; DUXU for learning; user experience evaluation methods and tools; DUXU practice; DUXU case studies.

Pharmacogenomics

Author : Showkat Ahmad Ganie
Publisher : Elsevier
ISBN 13 : 044315337X
Total Pages : 392 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Pharmacogenomics by : Showkat Ahmad Ganie

Download or read book Pharmacogenomics written by Showkat Ahmad Ganie and published by Elsevier. This book was released on 2023-06-13 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The editors lined up a group of worldwide experts to contribute to the book. Following a consistent chapter structure, the authors cover the foundational aspects of pharmacogenomics in the first four chapters of the book that include basic concepts, drug metabolism, drug discovery and development, and testing. The second part of the book is dedicated to detailed studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. Pharmacogenomics: From Discovery to Clinical Implementation is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. Researchers and graduate students in the related fields of Genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit of the structured approach of the book. Provides an in-depth review of pharmacogenomics and its role in drug discovery/metabolism and its clinical impacts Describes the practice of pharmacogenomics in the treatment of diabetes, cancers, cardiovascular diseases, psychiatric disorders, pulmonary diseases, infectious, gastroenterology, and autoimmune diseases Uses a consistent chapter structure to support understanding of the fundamental concepts in the area