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Phosphorus Metabolism Of The Brain
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Book Synopsis Phosphorus Metabolism of Brain by : Peter Joseph Heald
Download or read book Phosphorus Metabolism of Brain written by Peter Joseph Heald and published by . This book was released on 1960 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Phosphorus Metabolism of the Brain by : Maynard Manuel Cohen
Download or read book Phosphorus Metabolism of the Brain written by Maynard Manuel Cohen and published by . This book was released on 1953 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Phosphate Metabolism by : Shaul Massry
Download or read book Phosphate Metabolism written by Shaul Massry and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: We present to our readers the proceedings of the Second International Workshop on Phosphate. A short account of the history of the effort led to the Phosphate Workshops is appro priate and can be of interest to the reader. The idea for Phosphate Workshops was born in the early days of November, 1974. One of us (S. G. M. ) suggested the thought to a group of scientists gathered for a luncheon in one of the attrac tive small restaurants in Weisbaden, Germany. The purpose of the workshop was to bring together interested scientists to discuss the newer developments and the recent advances in the field of phosphate metabolism and the other related minerals. An Organizing Committee made of Shaul G. Massry (USA), Louis V. Avioli (USA), Philippe Bordier (France), Herbert Fleisch (Switzerland), and Eduardo Slatopolsky (USA) was formed. The First Workshop was held in Paris during June 5-6, 1975 and was hosted by Dr. Philippe Bordier. Its proceeding was already published. The Second Workshop took place in Heidelberg during June 28-30, 1976 and was hosted by Dr. Eberhard Ritz. Both of these workshops were extremely successful scientific endeavors, and the need for them was demonstrated by the great interest they generated among the scientific community. The Or ganizing Committee, therefore, decided to continue with the tradi tion to hold additional Workshops annually or every other year.
Book Synopsis Phosphorus Metabolism by : McCollum-Pratt Institute
Download or read book Phosphorus Metabolism written by McCollum-Pratt Institute and published by . This book was released on 1951 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Phosphorus Metabolism by : William David McElroy
Download or read book Phosphorus Metabolism written by William David McElroy and published by . This book was released on 1951 with total page 950 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Relationship of Brain Phosphate Metabolism and Cognition Using 31 Phosphorus Magnetic Resonance Spectroscopy at 7-Tesla in Alzheimer's Disease by : Namrata Das
Download or read book Relationship of Brain Phosphate Metabolism and Cognition Using 31 Phosphorus Magnetic Resonance Spectroscopy at 7-Tesla in Alzheimer's Disease written by Namrata Das and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial dysfunction, a neurometabolic marker, is considered an early marker in Alzheimer's disease (AD) that has speculated to precede toxic levels of amyloid and tau. Abnormal mitochondria function can negatively impact brain energy metabolism (BEM), oxidative and metabolic stress, leading to cell senescence and death. In-vitro cell line culture and postmortem AD studies suggest BEM abnormality, however have limited capability to capture the human brain's full complexity. Examining BEM in the in-vivo brain would confirm whether such abnormality is present and if so, to what extent, and how early it occurs in relation to the transitory stages of AD i.e., amnestic mild cognitive impairment (aMCI). The dissertation had three main goals. My first goal was to develop a methodology to measure BEM using advanced imaging technology such as 31-phosphorus magnetic resonance spectroscopy (31P MRS) at ultra-high-field (UHF) magnetic strength 7-T in human brain invivo. In the first phase, using partial volume-coil 31P MRS at 7-T over a brain region, i.e., parieto-occipital area, showed a well-separated high-resolution spectral display of thirteen metabolites signals, including energy phosphates and membrane phospholipid metabolites, in a single population of interest, i.e., aMCI. In my expanded research, I showed similar BEM data acquisition from the whole-brain volume-coil using same imaging technique. This work focused on three main energy phosphate metabolites-adenosine triphosphate (ATP), inorganic phosphate (Pi), and phosphocreatine (PCr). The measurements of these three metabolites were utilized to formulate three (3) BEM markers and two (2) regulatory co-factors [magnesium (Mg2+) and pH], including energy reserve index (PCr/t-ATP), energy consumption index (Pi/t-ATP), and metabolic state indicator (Pi/PCr). The next goal was to investigate if BEM markers and co-factors were significantly different across the three groups - cognitively normal (CN) (n=15), aMCI (n=15), and mild AD (n=11) in the four bilateral brain regions. The results showed that BEM markers was reduced in aMCI with further decrease in AD when compared to CN except metabolic state indicator. Interestingly, all the significant differences in BEM markers and regulatory co-factors were observed in the temporal region bilaterally, a vulnerable region where the AD pathology starts. The final goal was to study if the sensitive BEM markers and co-factors in the temporal lobe were associated with cognitive performance of memory, executive function (EF), attention, visuospatial skills, and language, respectively, across the groups. The findings showed a significant association of higher Mg2+ with improved memory, and EF in CN. On the other hand, in aMCI and mild AD, higher Mg2+ was related to lower performance in the same cognitive domains. Results suggest that in healthy brains, the Mg2+ supports the BEM mechanism, neuronal function and cognition. Whereas in aMCI and AD, the Mg2+ co-factor fails to support these systems. Overall, this work laid a foundation to investigate mitochondrial function using BEM in healthy and compromised brain in-vivo using novel and advanced imaging technology at UHF 7-T. Future work may explore ways to use this methodology using 31P MRS imaging technology to objectively measure the effectiveness of novel neurotherapeutics on mitochondrial function and dysfunction.
Book Synopsis A Review of the literature of phosphorus compounds in animal metabolism by : Ernest Browning Forbes
Download or read book A Review of the literature of phosphorus compounds in animal metabolism written by Ernest Browning Forbes and published by . This book was released on 1914 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Studies on the Phosphate Metabolism of Brain by : Douglas Arthur Hems
Download or read book Studies on the Phosphate Metabolism of Brain written by Douglas Arthur Hems and published by . This book was released on 1966 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Effect of Diisopropylfluorophosphate Administration on the Phosphorus Metabolism of Mouse Brain by : Walter Leland Nelson
Download or read book The Effect of Diisopropylfluorophosphate Administration on the Phosphorus Metabolism of Mouse Brain written by Walter Leland Nelson and published by . This book was released on 1958 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Metabolism in Different Parts of the Brain, Especially in the Epiphysis Measured with Radioactive Phosphorus by : Ulf Borell
Download or read book Metabolism in Different Parts of the Brain, Especially in the Epiphysis Measured with Radioactive Phosphorus written by Ulf Borell and published by . This book was released on 1945 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Review of the Literature of Phosphorus Compounds in Animal Metabolism by : Ernest Browning Forbes
Download or read book A Review of the Literature of Phosphorus Compounds in Animal Metabolism written by Ernest Browning Forbes and published by . This book was released on 1914 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Imaging Brain Metabolism by : Loreen Ruhm
Download or read book Imaging Brain Metabolism written by Loreen Ruhm and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Study of Human Cerebral Metabolism Using 31-phosphorus Magnetic Resonance Spectroscopy by : Nicholas S. R. Brooke
Download or read book The Study of Human Cerebral Metabolism Using 31-phosphorus Magnetic Resonance Spectroscopy written by Nicholas S. R. Brooke and published by . This book was released on 1997 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Phosphorus metabolism by : Phosphorus metabolism
Download or read book Phosphorus metabolism written by Phosphorus metabolism and published by . This book was released on 1951 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Phospholipid Metabolism in Brain in Vitro by : Roger Morazain
Download or read book Phospholipid Metabolism in Brain in Vitro written by Roger Morazain and published by . This book was released on 1965 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only in the last two decades that the metabolic origin and function of phospholipids have lost some of their mystery. Thudichum (1, 2) reported in the 1880's the occurrence of lipid-associated phosphorus, and later studies only succeeded in establishing the general importance of this class of lipids as constituents of tissues. [...]
Book Synopsis Metabolism of the Nervous System by : Derek Richter
Download or read book Metabolism of the Nervous System written by Derek Richter and published by Pergamon. This book was released on 1957 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism of the Nervous System ...
Book Synopsis Phosphorus Metabolism by : Symposium on Phosphorus Metabolism (2nd:Baltimore:1952)
Download or read book Phosphorus Metabolism written by Symposium on Phosphorus Metabolism (2nd:Baltimore:1952) and published by . This book was released on 1952 with total page 930 pages. Available in PDF, EPUB and Kindle. Book excerpt: