Oxidative Stress And Inflammation As Targets For Novel Preventive And Therapeutic Approaches In Non Communicable Diseases Ii

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Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approaches in Non-Communicable Diseases II

Author : Monica Dinu
Publisher : Mdpi AG
ISBN 13 : 9783036543635
Total Pages : 224 pages
Book Rating : 4.5/5 (436 download)

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Book Synopsis Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approaches in Non-Communicable Diseases II by : Monica Dinu

Download or read book Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approaches in Non-Communicable Diseases II written by Monica Dinu and published by Mdpi AG. This book was released on 2022-06-02 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-communicable diseases are chronic non-infectious pathologies that represent the leading cause of death and disability for the general population. Oxidative stress and inflammation induce and modulate several signaling pathways that play a crucial role in the pathophysiology and progression of these diseases. Therefore, they represent a good target for the development of different therapeutic strategies and open new strategies for assessment and intervention. This book focuses on different approaches to investigate the underlying pathogenesis and treatment mechanisms of conditions related to oxidative stress and inflammation. Particular attention is given to biomarkers specific to these features that can detail the pathogenesis and evolution of kidney disease, cardiovascular disease, obesity, breast cancer, and idiopathic pulmonary fibrosis. In addition, the potential medicinal and beneficial effects of plant compounds such as oleuropein, columbianadin, and rebaudioside A are addressed.

Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approches in Non Communicable Diseases

Author : Chiara Nediani
Publisher : MDPI
ISBN 13 : 3039289357
Total Pages : 270 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approches in Non Communicable Diseases by : Chiara Nediani

Download or read book Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approches in Non Communicable Diseases written by Chiara Nediani and published by MDPI. This book was released on 2020-12-02 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-communicable diseases (NCDs) are chronic diseases that include most ageing-related diseases, representing the main cause of death and disability in the general population. Inflammation and oxidative stress are common features in NCDs, responsible for the cell, tissue, and organ damage that contributes to the progression of these diseases. They may be also key targets for the development of novel preventive and therapeutic strategies. This Special Issue includes 14 peer-reviewed papers, including 12 original research papers and 2 reviews. Together, they represent the most recent progress in the field of several degenerative disorders, aiming to establish specific biomarkers, detailing the pathogenesis and the evolution of these diseases, making a correct diagnosis, and opening up new therapeutic strategies. Of relevance, many studies report the beneficial effects of natural compounds, derived from several plants, leaves, and fruits; their antioxidant and anti-inflammatory properties suggest their use as a dietary supplement for prevention and/or complement to standard therapies.

Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approches in Non Communicable Diseases

Author : Chiara Nediani
Publisher :
ISBN 13 : 9783039289363
Total Pages : 268 pages
Book Rating : 4.2/5 (893 download)

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Book Synopsis Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approches in Non Communicable Diseases by : Chiara Nediani

Download or read book Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approches in Non Communicable Diseases written by Chiara Nediani and published by . This book was released on 2020 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-communicable diseases (NCDs) are chronic diseases that include most ageing-related diseases, representing the main cause of death and disability in the general population. Inflammation and oxidative stress are common features in NCDs, responsible for the cell, tissue, and organ damage that contributes to the progression of these diseases. They may be also key targets for the development of novel preventive and therapeutic strategies. This Special Issue includes 14 peer-reviewed papers, including 12 original research papers and 2 reviews. Together, they represent the most recent progress in the field of several degenerative disorders, aiming to establish specific biomarkers, detailing the pathogenesis and the evolution of these diseases, making a correct diagnosis, and opening up new therapeutic strategies. Of relevance, many studies report the beneficial effects of natural compounds, derived from several plants, leaves, and fruits; their antioxidant and anti-inflammatory properties suggest their use as a dietary supplement for prevention and/or complement to standard therapies. Special thanks to all authors and reviewers for their valuable contributions and constructive suggestions and to the publishing team of Antioxidants for their help in compiling this Special Issue.

Oxidative Stress and Inflammation in Non-communicable Diseases - Molecular Mechanisms and Perspectives in Therapeutics

Author : Jordi Camps
Publisher : Springer
ISBN 13 : 3319073206
Total Pages : 223 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Oxidative Stress and Inflammation in Non-communicable Diseases - Molecular Mechanisms and Perspectives in Therapeutics by : Jordi Camps

Download or read book Oxidative Stress and Inflammation in Non-communicable Diseases - Molecular Mechanisms and Perspectives in Therapeutics written by Jordi Camps and published by Springer. This book was released on 2014-07-19 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress and inflammation underpin most diseases; their mechanisms are inextricably linked. For example, chronic inflammation is associated with oxidation, anti-inflammatory cascades are linked to decreased oxidation, increased oxidative stress triggers inflammation and redox balance inhibits the inflammatory cellular response. Whether or not oxidative stress and inflammation represent the causes or the consequences of cellular pathology, they contribute significantly to the pathogenesis of non-communicable diseases. The incidence of obesity and other related metabolic disturbances are rising, as are age-related diseases due to progressively aging populations. Interrelations between the mechanisms of oxidative stress and of inflammatory signaling and metabolism are, in the broad sense of energy transformation, being increasingly recognized as part of the problem in non-communicable diseases. The book Oxidative Stress and Inflammation in Non-communicable Diseases: Molecular Mechanisms and Perspectives in Therapeutics is an update on the latest research on the molecular basis of non-communicable diseases and the search for possible therapeutic alternatives. The authors of this monograph are experts in their field and the book as a whole, provides an overview of the biochemical alterations underlying diseases such as cardiovascular disease, cancer, obesity, renal disease, neurological diseases and diabetes, emphasizing those aspects that they share in common. We hope that this book will be useful for researchers in biomedicine and also for physicians interested in finding the root causes of the disease, as well as for post-graduate students in biochemistry, molecular biology, nutrition or medicine.

Novel Therapeutic Approaches Targeting Oxidative Stress

Author : Pawan Kumar Maurya
Publisher : Academic Press
ISBN 13 : 032390906X
Total Pages : 294 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Novel Therapeutic Approaches Targeting Oxidative Stress by : Pawan Kumar Maurya

Download or read book Novel Therapeutic Approaches Targeting Oxidative Stress written by Pawan Kumar Maurya and published by Academic Press. This book was released on 2022-02-18 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Therapeutic Approaches Targeting Oxidative Stress investigates the role of oxidative stress in disease and explores the latest methods and approaches to targeting oxidative stress for treatment and diagnosis. The book begins with an introduction to oxidative stress and its significance. Subsequent sections cover biochemical methods for detecting free radicals and novel therapeutic approaches for targeting oxidative stress in a number of different diseases. This includes age-related illnesses, neuropsychiatric disorders such as schizophrenia and bipolar disorder, and neurodegenerative diseases like Alzheimer's and Parkinson's disease. Novel approaches for targeting oxidative stress in cancer and cardiovascular diseases are also explored. The book then moves on to discuss advances in drug delivery systems and detecting oxidative stress biomarkers using biosensors. It concludes with case studies that illustrate the targeting of oxidative stress and future perspectives. - Explores oxidative stress in a variety of diseases, including neurological disorders, cardiovascular diseases, age-related diseases, and cancer - Covers a range of therapeutic approaches to target oxidative stress - Includes chapters on the application of novel drug delivery systems and diagnostic biosensors to oxidative stress - Features case studies illustrating the targeting of oxidative stress

Oxidative Stress, Inflammation, and Health

Author : Young-Joon Surh
Publisher : CRC Press
ISBN 13 : 1420028251
Total Pages : 670 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Oxidative Stress, Inflammation, and Health by : Young-Joon Surh

Download or read book Oxidative Stress, Inflammation, and Health written by Young-Joon Surh and published by CRC Press. This book was released on 2005-05-24 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specifically focusing on the redox regulation of cell signaling responsible for oxidative stress and inflammatory tissue damage, this reference provides a comprehensive overview of cutting-edge research on the intracellular events mediating or preventing oxidative stress and pro-inflammatory processes induced by endogenous and xenobiotic factors-an

Oxidative Stress and Inflammation as Therapeutic Targets of High-fat Diet-induced Metabolic Diseases

Author : Eric L. Kendig
Publisher :
ISBN 13 :
Total Pages : 210 pages
Book Rating : 4.:/5 (796 download)

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Book Synopsis Oxidative Stress and Inflammation as Therapeutic Targets of High-fat Diet-induced Metabolic Diseases by : Eric L. Kendig

Download or read book Oxidative Stress and Inflammation as Therapeutic Targets of High-fat Diet-induced Metabolic Diseases written by Eric L. Kendig and published by . This book was released on 2009 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are faced with a metabolic disease pandemic. The prevalence of obesity-related metabolic diseases has increased exponentially in the last 50 years, in large part from a sedentary lifestyle and consumption of a diet high in fat (HFD) and simple sugars. Many diet-induced metabolic diseases, such as type 2 diabetes, atherosclerosis and non-alcoholic fatty liver disease, are associated with obesity. The direct connection between metabolic diseases and obesity is in part related to the development of low grade inflammation and disruption of metabolic regulation caused by oxidative stress. Using mouse models, we demonstrate the therapeutic potential of antioxidants and over-the-counter anti-inflammatory drugs in targeting and preventing diet-induced metabolic disease, and conclude that oxidative stress and inflammation provide common etiological mechanisms and potential therapeutic targets for prevention or reversal of diet-induced metabolic diseases. Consumption of a HFD causes dramatic changes in physiology of an individual. In particular, dyslipidemia induced by consumption of a high-fat or unbalanced diet can cause alterations in the structure and function of adipose, vasculature, liver, and muscle. Chronic imbalance in plasma lipids can cause an oxidative response in these tissues through the induction of the NADPH oxidase (NOX) complex, producing superoxide anion (O2) in the cytoplasm. Chronic activation of NOX results in overproduction of reactive oxygen, which can alter expression of adipose tissue-derived cytokines and inflammatory mediators such as adiponectin, leptin, visfatin, resistin, TNF[alpha], IL-6, and IL-1[beta]. Disruption of these signals cause global modulation of metabolism, resulting in accumulation of lipid in muscle and liver, elevation of blood pressure, and insulin resistance. Treating mice with antioxidants and anti-inflammatory drugs prevents the development of obesity, insulin resistance, and dyslipidemia, suggesting that ablation of this common etiological factor in metabolic disease may prove a useful therapeutic strategy for disease prevention or reversal. The analgesic drug, acetaminophen (APAP), demonstrated the greatest effect in preventing HFD-induced metabolic disease in mice, likely through its combined anti-inflammatory and antioxidant potential. Other over-the-counter analgesic drugs and antioxidants were tested yielding similar results. One potentially important mechanism for APAPs protective effects is the inhibition of NOX activity in white adipose tissue, which may help to maintain normal adipose homeostasis. We have also examined the protective effects of endogenous antioxidant systems in preventing diet-induced metabolic disease. Mice lacking the modifier subunit [Gclm ( -/- )] of glutamate cysteine ligase (GCL) were fed a HFD for 10 weeks and compared to wildtype [Gclm (+/+)] mice. We found that Gclm ( -/- ) mice were resistant to diet-induced obesity and hepatic lipid accumulation. Gclm ( -/- ) mice also appeared to have higher basal metabolic rate, indicated by increased systemic oxygen consumption.Combined, these findings highlight the importance of oxidative stress in the development of diet-induced metabolic disease, and provide a common etiological target for development of new therapeutic strategies. Further characterization of the effects of oxidative stress in development of these diseases may provide more specific targets for prevention or reversal of HFD-induced metabolic diseases.

Novel Prospects in Oxidative and Nitrosative Stress

Author : Pinar Atukeren
Publisher : BoD – Books on Demand
ISBN 13 : 1789230861
Total Pages : 158 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Novel Prospects in Oxidative and Nitrosative Stress by : Pinar Atukeren

Download or read book Novel Prospects in Oxidative and Nitrosative Stress written by Pinar Atukeren and published by BoD – Books on Demand. This book was released on 2018-05-09 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress plays a crucial role in the pathophysiology of various diseases when there is a disruption of the intracellular redox balance and the homeostatic balance between cellular oxidants and antioxidants. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) react with molecular targets including proteins, lipids, and nucleic acids contributing to mitochondrial injury and cellular dysfunction. This book intends to provide the readers with an extensive overview of the novel approaches and prospects based on oxidative and nitrosative stress in the pathophysiology of various diseases and in the current treatment strategies with antioxidants.

Inflammation, Lifestyle and Chronic Diseases

Author : Bharat B. Aggarwal
Publisher : CRC Press
ISBN 13 : 1439839891
Total Pages : 515 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Inflammation, Lifestyle and Chronic Diseases by : Bharat B. Aggarwal

Download or read book Inflammation, Lifestyle and Chronic Diseases written by Bharat B. Aggarwal and published by CRC Press. This book was released on 2011-07-27 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress and inflammation are among the most important factors of disease. Chronic infections, obesity, alcohol and tobacco usage, radiation, environmental pollutants, and high-calorie diets have been recognized as major risk factors for a variety of chronic diseases from cancer to metabolic diseases. All these risk factors are linked to chronic diseases through inflammation. While short-term, acute inflammation generated by the immune system serves a therapeutic role, chronic low-level inflammation that may persist "silently" for decades is responsible for chronic diseases. Inflammation, Lifestyle, and Chronic Diseases: The Silent Link describes the role of dysregulated inflammation in persistent and recurring diseases. It investigates links to lifestyle and presents research on how the suppression of proinflammatory pathways may provide opportunities for both prevention and treatment of chronic diseases. The book covers neurodegenerative diseases, pulmonary diseases, asthma, rheumatic and arthritic diseases, skin disease, heart disease, chronic wounds, infectious disease, neuropsychiatric disorders such as depression, gastrointestinal diseases, insulin resistance, and cancer, many of which are also diseases of old age. For each chronic disease, contributors review the clinical and scientific literature and examine current and potential therapies, including conventional pharmacotherapies as well as natural products. Noting that the long-term use of steroids and nonsteroidal anti-inflammatory drugs (NSAIDs) can cause adverse side effects, many of the chapters address the role of dietary agents such as fruits, vegetables, legumes, pulses, nuts, and spices as ideal anti-inflammatory agents that can be consumed regularly. The book also suggests directions for further research. Clinical and science researchers, students, and health professionals interested in the link between inflammation, lifestyle, and chronic diseases will find this an informative resource.

Inflammation, Oxidative Stress, and Cancer

Author : Ah-Ng Tony Kong
Publisher : CRC Press
ISBN 13 : 9781138199842
Total Pages : 640 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Inflammation, Oxidative Stress, and Cancer by : Ah-Ng Tony Kong

Download or read book Inflammation, Oxidative Stress, and Cancer written by Ah-Ng Tony Kong and published by CRC Press. This book was released on 2016-11-16 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing scientific evidence suggests that the majority of diseases including cancer are driven by oxidative stress and inflammation, attributed to environmental factors. These factors either drive genetic mutations or epigenetically modify expression of key regulatory genes. These changes can occur as early as gestational fetal development, and major questions remain as to how dietary/nutritional phytochemical factors biochemically interact with such genetic and epigenetic events. With chapters written by international experts, Inflammation, Oxidative Stress, and Cancer: Dietary Approaches for Cancer Prevention examines the latest developments on the effects of various dietary phytochemicals. Divided into nine sections, the book begins with the basic mechanisms of inflammation/oxidative stress-driven cancer, including an overview of the topic and how to prevent carcinogenesis, the role of obesity in inflammation and cancer, and antioxidant properties of some common dietary phytochemicals. Subsequent sections cover cellular signal transduction, molecular targets, and biomarkers of dietary cancer-preventive phytochemicals, as well as their potential challenges with in vivo absorption and pharmacokinetics. The chapters also examine the cancer-preventive properties of various classes of phytochemicals, including vitamins A, D, and E; omega-3 and omega-6 fatty acids; flavanoids and polyphenols; garlic organosulfur compounds and cruciferous glucosinolates; and selenium, traditional Chinese herbal medicines, and alpha lipoic acid. The final section of the book explores the latest developments on the interactions of dietary phytochemicals through epigenetics and the management of chronic inflammation with nutritional phytochemicals.

Oxidative Stress and Inflammation

Author : Juan Gambini
Publisher :
ISBN 13 : 9783036560243
Total Pages : 0 pages
Book Rating : 4.5/5 (62 download)

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Book Synopsis Oxidative Stress and Inflammation by : Juan Gambini

Download or read book Oxidative Stress and Inflammation written by Juan Gambini and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the biochemical reactions that take place within all living beings, species called free radicals are generated. Denham Harman, in his study on the origin and evolution of life (Harman, 2001), proposes that these species are amongst the causes of the origin of life on our planet. Oxygen is a molecule that provides the primary source of energy in aerobic organisms and therefore is key to the development and evolution of life. On the one hand, it gives rise to life; on the other, due to its ability to form different free radicals, it is capable of damaging essential structures for development. To combat these radicals, our biological systems have developed antioxidant defenses. However, when the balance between free radicals and antioxidant defenses is broken in favor of the former, a phenomenon called oxidative stress occurs, which ends up damaging molecules such as DNA, proteins, carbohydrates, and lipids (Sies, 1983) (Halliwell and Gutteridge, 1985). This phenomenon is implicated both in the development of diseases and in their progression. In addition, inflammation phenomena are also involved in most pathologies, which, although they are essential for tissue repair and immunity, turn against our bodies when they become excessively active. For these reasons, in this special edition we showcase an extensive knowledge of the effects of oxidative stress and inflammation both in diseases such as aging, or for its role in health.

Mitochondrial Dysfunction

Author : Lawrence H. Lash
Publisher : Elsevier
ISBN 13 : 1483218619
Total Pages : 527 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Mitochondrial Dysfunction by : Lawrence H. Lash

Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Oxidative Stress in Lung Diseases

Author : Sajal Chakraborti
Publisher : Springer
ISBN 13 : 9789813293687
Total Pages : 488 pages
Book Rating : 4.2/5 (936 download)

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Book Synopsis Oxidative Stress in Lung Diseases by : Sajal Chakraborti

Download or read book Oxidative Stress in Lung Diseases written by Sajal Chakraborti and published by Springer. This book was released on 2021-01-22 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second volume of the comprehensive, two-volume work on oxidative stress in lung diseases. Adopting a multidisciplinary approach, it demonstrates the cellular and molecular mechanisms associated with ROS (reactive oxygen species)-induced initiation and progression of a variety of lung diseases, such as COPD, emphysema, asthma, cystic fibrosis, occupational pulmonary diseases and pulmonary hypertension and discusses points for therapeutic intervention. The book also covers translational research and the latest research on prevention and therapeutics. Each chapter includes in-depth insights into the mechanisms associated with lung diseases and into identifying targets for drug development. Bridging the gap between fundamental and translational research, and examining applications in the biomedical and pharmaceutical industry, it is a thought- provoking read for basic and applied scientists engaged in biomedical research.

Bioactive Food Components Activity in Mechanistic Approach

Author : Cinthia Bau Betim Cazarin
Publisher : Academic Press
ISBN 13 : 0128225904
Total Pages : 257 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Bioactive Food Components Activity in Mechanistic Approach by : Cinthia Bau Betim Cazarin

Download or read book Bioactive Food Components Activity in Mechanistic Approach written by Cinthia Bau Betim Cazarin and published by Academic Press. This book was released on 2021-11-22 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioactive Food Components Activity in Mechanistic Approach presents the role of functional foods and bioactive compounds in inflammation. This book focuses on bioactive compounds, including phenolics, prebiotics, carotenoids, tocopherols, bioactive peptides, probiotics, polyunsaturated and monounsaturated fatty acids, and describes their actions in several diseases, mainly obesity and co-morbidities, inflammatory bowel disease, cognitive decline and cancer, and aging. Intended for food, nutrition, and nutraceutical researchers, as well as those studying related fields, the book offers a mechanistic approach that is currently lacking in the market. - Explores the mechanistic approach of functional foods in health and disease - Contains definitions, case studies, applications, literature reviews, recent developments and text boxes - Provides coverage of phenolic compounds, prebiotics and probiotics, carotenoids, tocopherols, bioactive peptides, polyunsaturated and monounsaturated fatty acids, and sulfur compounds

How Tobacco Smoke Causes Disease

Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Basic Protocols in Foods and Nutrition

Author : Cinthia Baú Betim Cazarin
Publisher : Springer Nature
ISBN 13 : 1071623451
Total Pages : 406 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Basic Protocols in Foods and Nutrition by : Cinthia Baú Betim Cazarin

Download or read book Basic Protocols in Foods and Nutrition written by Cinthia Baú Betim Cazarin and published by Springer Nature. This book was released on 2022-06-07 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive knowledge and a detailed step by step description of experimental protocols for the determination of food intake, body weight changes, and some metabolic markers. Chapters are split into two parts detailing experimental diets, monitor food intake, weight gain, evaluate biological samples, predict physiological changes, evaluate bioavailability of bioactive, anamnesis, measure the metabolic rate, assessing the body composition, assessing glucose homeostasis, and monitoring the metabolomic pathways. Authoritative and cutting-edge, Basic Protocols in Foods and Nutrition aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.

Oxidative Stress and Signal Transduction

Author : H.J. Forman
Publisher : Springer Science & Business Media
ISBN 13 : 1461559812
Total Pages : 484 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Oxidative Stress and Signal Transduction by : H.J. Forman

Download or read book Oxidative Stress and Signal Transduction written by H.J. Forman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few years there has been the increased recognition that the effects of oxidative stress are not limited to the damage of cellular constituents. There is now evidence that reactive oxygen species (ROS) can alter cell function by acting upon the intermediates, or second messengers, in signal transductions. Such effects on signaling mechanisms probably account for the role of oxidative stress in inflammation, aging, and cancer. This volume brings together internationally recognized researchers in both the major areas covered by the book, oxidative stress and signal transduction. The work is organized in three sections. The first deals with the immediate cellular responses to oxidative stress and the production of second messengers. The second details the connection between second messengers and the gene. The third part looks more closely at the level of the gene.