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New Experimental Modalities In The Control Of Neoplasia
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Book Synopsis New Experimental Modalities in the Control of Neoplasia by : Prakash Chandra
Download or read book New Experimental Modalities in the Control of Neoplasia written by Prakash Chandra and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acquisition of new knowledge about the biological and bio chemical nature of neoplastic cells has led to the design and development of several experimental approaches in the tre&tment of cancer. These approaches emerge from the recent work in tu mor virology, e. g. the control of vital cellular genes by viral regulatory signals; the implication of monoclonal antibodies as a vehicle for the targeted drug delivery and selective de struction of tumor cells; immunologic advances in the recog nition of some specific events during metastatic growth; the role of biological response modifiers in modifying or rever sing malignant growth; and biochemical advances, such as the role of gene amplification in drug resistance and the app roaches to the reversal of resistance in drug refractory cancer, the role of membranes in designing useful strategies, the identification of new enzymic targets in some types of cancer cells, and the characterization of metabolically active forms of cytostatic compounds. These are the important issues which were addressed in an international NATO Advanced Study Institute (ASI) attended by scientists from allover the world representing a wide spectrum of scientific disciplines. Although the acquired immune deficiency syndrome (AIDS) is not a malignant disease, but the etiological involvement of a retrovirus belonging to the family of human T-cell lympho tropic viruses which cause leukemia and lymphomas in man, justifies its inclusion in the agenda of this Study Institute. Scientific presentations from Drs.
Book Synopsis Current Catalog by : National Library of Medicine (U.S.)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1712 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1028 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Annual Report by : National Cancer Institute (U.S.). Division of Cancer Etiology
Download or read book Annual Report written by National Cancer Institute (U.S.). Division of Cancer Etiology and published by . This book was released on 1987 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Comparative Oncology by : Alecsandru Ioan Baba
Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Hereditary Malignant Melanoma by : Ramon M. Fusaro
Download or read book Hereditary Malignant Melanoma written by Ramon M. Fusaro and published by CRC Press. This book was released on 2019-05-17 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1991: The book focuses only on hereditary malignant melanoma. The epidemic of cutaneous melanoma which is now occurring in the sun belt areas of the world is due partly to a susceptible subgroup of Caucasians who have immigrated there.
Download or read book Cancer selection written by James Graham and published by Aculeus Pr. This book was released on 1992 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conventional evolutionary theory cannot explain the existence of humans & other complex animals; another mechanism is needed, says James Graham, & it is none other than cancer. This radical theory, already published in a science journal, is aimed at amateurs & professionals. "I think I agree with him... a good idea," John W. Galloway, Nature. "Intriguing...resolves many outstanding problems," SciTech Book News. Literary reviewers like it too: "absorbing...provocative." The Small Press Book Review. "fascinating...sheer intellectual virtuosity." West Coast Review of Books. "distinguished." The Book Reader. Order from: James Graham, PO Box 142, Lexington Virginia 24450 telephone 540 464 4554. Also available from Amazon.com, Barnes & Noble and other retailers.
Book Synopsis Recent Progress of Life Science Technology in Japan by : Yoji Ikawa
Download or read book Recent Progress of Life Science Technology in Japan written by Yoji Ikawa and published by Academic Press. This book was released on 2014-06-28 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Progress of Life Science Technology in Japan discusses developments in cancer research technologies in Japan. In June 1983 an intra-cabinet panel of the Japanese Government drafted a 10-year strategy for cancer control, recognizing the importance of this field of research. A scientific research group was organized to comprise two sections—the first concerning the development and evaluation of DNA technologies, and the second on protein-related technologies. In the promotion of fundamental cancer research, the development and refinement of basic technologies for each component of the ""triangle of bio-sciences""—DNA, protein, and antibody—are essential, particularly in the elucidation of tumor-inducing and tumor-suppressing genes, tumor-specific antigens, and so forth. Part I of the book details the achievements of the first group in developing automated instrumentations for DNA sequencing. The second scientific research group worked on three major subareas: (1) gene transfer and expression technologies; (2) technologies for extraction, purification, and structural analysis of cancer-related proteins; and (3) technologies for analysis and synthesis of saccharide chains. Reports from these areas are respectively grouped in Part II, Part III, and Part IV of this monograph.
Book Synopsis Enzyme Chemistry by : Colin Suckling
Download or read book Enzyme Chemistry written by Colin Suckling and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the first edition of this book was going through the publication process, a revolution was taking place in the technologies available for the study of enzymes. The techniques of molecular biology, especially in genetic engineering of organisms and in site specific mutagenesis of genes, were established and were being brought into use to solve many problems in in enzymology. Added to these fundamental and applied science, not least advances the possibility of generating catalysts from antibodies has become a topic of major interest. These major innovations have changed the emphasis of much bioorganic research; whereas in the past, the protein was often the 'sleeping partner' ina study, its detailed function is now the major focus of scientific interest. Similarly in industry, the potential of genetically manipulated organisms to satisfy the needs for the production of chemicals and foodstuffs has been widely recognised. The second edition of 'Enzyme Chemistry, Impact and Applications' takes on board these new develop ments whilst maintaining the overall aims and views of the first edition. Many of the chapters have been completely rewritten to take account of advances in the last five years especially with regard to the impact of biologically based technologies. Although the book continues to approach its subject matter from the point of view of the chemist, the increased interdisciplinary content of much modern science will be obvious from the discussion.
Book Synopsis The Molecular Basis of B-Cell Differentiation and Function by : M. Ferrarini
Download or read book The Molecular Basis of B-Cell Differentiation and Function written by M. Ferrarini and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: The progress in protein and nucleic acid chemistry together with improvements of the previously employed tissue culture techniques have led to the solution of problems such as that of the generation of antibody diversity or of the molecular structure of T and B cell membrane receptor for antigen which had challenged the past generations of immunologists. Thanks to this progress an impressive amount of knowledge has been accumulated on certain cell types that were relatively "mysterious" until recently. The B lymphocyte represents a typical example of such a cell. With these considerations in mind, we have started to organize a NATO summer school on "The molecular basis of B cell differentation and function" that had the specific aim of bringing up to date a selected number of young investigators. During the course, held in Santa Margheri ta Ligure, October 1-11, 1985 it became apparent that rather than a formal school we had organized an informal series of Workshops where both the Faculty members and the participants were discussing their own data in addition to reviewing the general progress in the field. The deep commi ttment of everyone to his research subj ect and the enthusiasm had caused this very successful change in the shape of the course. At the end we asked the members of the Faculty and the participants to write a summary of their data and of their point of view on selected subj ect s.
Book Synopsis Methods for the Mycological Examination of Food by : A.D. King Jr.
Download or read book Methods for the Mycological Examination of Food written by A.D. King Jr. and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The desirability, indeed the necessity, for standardization of methods for the examination of foods for contaminant and spoilage mycoflora has been apparent for some time. The concept of a specialist workshop to address this problem was borne during conversations at the Gordon Research Conference on "Hicrobiological Safety of Foods" in Plymouth, New Hampshire, in July 1982. Discussions at that time resulted in an Organizing Committee of four, who became the Editors, and a unique format: all attendees would be expected to contribute and, in most cases, more than once; and papers in nearly all sessions would be presented as a set of data on a single topic, not as a complete research paper. Each session would be followed by general discussion, and then a panel would formulate recommendations for approval by a final plenary session. The idea for this format was derived from the famous "Kananaskis I" workshop on Hyphomycete taxonomy and terminology organized by Bryce Kendrick of the University of Waterloo, Ontario in 1969. Attendance would necessarily be limited to a small group of specialists in food mycology. The scope of the workshop developed from answers to questionnaires circulated to prospective participants. To generate new data which would allow valid comparisons to be drawn, intending participants were given a variety of topics as assignments and asked to bring information obtained to the workshop.
Book Synopsis Auditory Frequency Selectivity by : Brian Moore
Download or read book Auditory Frequency Selectivity written by Brian Moore and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most fundamental aspects of the auditory system is its frequency selectivity - the ability to resolve a complex sound into frequency compOhents. This ability plays a role in many aspects of auditory perception, including: the masking of one sound by another; the perception of pitch for pure tones and complex tones; the perception of timbre; the perception of the relative phase of components in complex sounds; and the perception of loudness. Over the last decade, there have been considerable advances in our understanding of frequency selectivity, both at the physiological and psychophysical level, and rapid progress continues to be made. This book summarizes the proceedings of a NATO Advanced Research Workshop on Auditory Frequency Selectivity which was held in Wolfson College, Cambridge from June 23rd to 27th, 1986. The Workshop brought together leading researchers from all disciplines relevant to the topic, with the aim of reviewing and consolidating the latest research findings, and identifying areas of uncertainty or controversy where further research is needed. The book is aimed primarily at research scientists and research students in the fields of psychology, audiology, auditory physiology, biophysics, medicine, acoustical engineering, noise control, communication and speech science. It should also be useful for advanced undergraduates in these disciplines. A feature of the book is that it includes summaries of the discussions which followed the presentation of each paper at the Workshop.
Book Synopsis Radiation Carcinogenesis and DNA Alterations by : Frederic J. Burns
Download or read book Radiation Carcinogenesis and DNA Alterations written by Frederic J. Burns and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is based on the proceedings of an Advanced Study Institute (ASI) sponsored by the North Atlantic Treaty Organization (NATO) held October 1984 in Corfu, Greece. The meeting received finan cial support from the United States Department of Energy and the United States National Cancer Institute. A plethora of recent developments in the molecular biology of DNA are leading to new ideas concerning how DNA alterations might be involved in the mechanism of radiation carcinogenesis. Evidence is accumulating that genetic sequences, known as oncogenes, are involved in the translation of DNA molecular alterations into phenotypic changes associated with malignant cells. For example, a chromosome break often occurs at or near the loca tion of a specific oncogene in Burkitt's lymphoma. Such breaks could represent initial lesions in a translocation process that activates the oncogene by inserting it at a new location, eg., near an active pro moter. Since breakage of the DNA is one of the principal ways that ion izing radiation affects mammalian cells, these new molecular ideas sug gest ways that radiation-induced DNA breaks might be involved as initial events in carcinogenesis. While the possible involvement of oncogenes in radiation carcino genesis is an exciting new development, a direct sequential connection between early molecular changes in DNA and later tumor development has yet to be established. Accordingly, there is a tremendous need for experimental studies of how DNA alterations might convert normal cells to cancer cells.
Book Synopsis Delivery Systems for Peptide Drugs by : S.S. Davis
Download or read book Delivery Systems for Peptide Drugs written by S.S. Davis and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen enormous advances in the field of protein and peptide engineering and a greater understanding in the way in which biological response modifiers function in the body. It is now possible through the use of recombinant DNA techniques, or by solid phase protein synthesis, to produce significant quantities of a wide variety of regulatory agents that are therapeutically applicable. The list of these response modifiers expands almost daily to include interferons, macrophage activation factors, neuropeptides and agents that may have potential in cardiovascular disease, inflammation, contraception etc. Prospects to use some of these materials in medicine have reached the stage where products have either been approved by regulatory authorities or are the subject of applications as investigatory drugs or as new therapeutic agents. In some uses the pertinent agent will be administered on an acute basis in the form of a simple injection, as, for example, the use of a tissue plasminogen activator for the treatment of coronary infarct. In other cases regulatory proteins and peptides are indicated for chronic therapy and here they will need to be administered by an appropriate delivery system. Unfortunately, the research on delivery systems for peptides and proteins has not kept pace with the rapid progress in biotechnology and, consequently, there are presently few systems that are entirely appropriate for the administration of macromolecular drugs according to complex dosage regimens, (eg intermittent and pulsed therapy). Furthermore essential pharmacokinetic and pharmacodynamic data may be missing.
Download or read book Cyst Nematodes written by F. Lamberti and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cyst nematodes are a major group of plant pathogens of economic importance in many countries throughout the world. Considerable yield losses have been attributed to cyst nematodes attacking potatoes, sugar beet, soybean and cereals. Because of the protective cyst that is formed, which encloses the eggs, they pose special problems in their control and also in preventing their distribution in soil from infested areas. There has been much research on many aspects of the biology of cyst nematodes and the large number of publications are testimony to their importance as crop pests and of the interest of nematologists in the group. Nevertheless, they continue to pose problems because of the complexity of their phylogeny and taxonomy and there is still much to be investigated on their biology, particularly with those aspects which relate to improving the effectiveness of control. In many respects the biology of the various cyst nematode species is similar, although with variations due to different interactions with hosts and geographical location. Thus, research on any one species has general applicability and this is particularly so with regard to evaluation of control measures, or to the methodology of soil sampling for the assessment of populations prior to growing crops.
Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.
Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Book Synopsis Resistance to Antitumor Agents by : M. Ghione
Download or read book Resistance to Antitumor Agents written by M. Ghione and published by CRC Press. This book was released on 1989 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on lectures given at the Ettore Majorana Centre's 25th Course on Resistance to Antitumor Agents in the Laboratory and Clinic: Problems and Implications, April 1988. A number of compounds have properties that inhibit the proliferation of neoplastic cells, and these compounds make up a large array of therapeutic agents now available to the physician treating cancer patients. Experimental evidence and controlled clinical trials have shown that the failure to reach the expected goal during treatment is principally due to the emergence of drug resistant cancer cell clones. The therapist's task is to design schedules using single or combined treatments in order to prevent or circumvent the obstacle of drug resistance. This book aims to update clinical oncologists dealing with this problem. Book club price, $51. Annotation copyrighted by Book News, Inc., Portland, OR
