Neural Immune Interactions In Brain Function And Alcohol Related Disorders

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Neural-Immune Interactions in Brain Function and Alcohol Related Disorders

Author : Changhai Cui
Publisher : Springer Science & Business Media
ISBN 13 : 1461447291
Total Pages : 587 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Neural-Immune Interactions in Brain Function and Alcohol Related Disorders by : Changhai Cui

Download or read book Neural-Immune Interactions in Brain Function and Alcohol Related Disorders written by Changhai Cui and published by Springer Science & Business Media. This book was released on 2012-11-14 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in neuroinflammatory response, have been implicated in the regulation of neuronal function and plasticity. Thus, neural-immune interactions provide a new frame work for understanding the role of the neuroimmune system in normal brain function, neurodevelopment, and a variety of neurological disorders. These advances have a far reaching impact on many areas of neuroscience, including alcohol research. Studies using human alcoholic brains, gene knockout mice, and gene expression profiling have established a clear link between alcoholism and an altered neuroimmune profile. This book integrates emerging knowledge on neural-immune interactions with key discoveries in alcohol research and provides a comprehensive overview of neural-immune interactions in brain function and behavior associated with alcohol use disorders. While Neural–Immune Interaction in Brain Function and Alcohol Related Disorders focuses on neural-immune interactions in areas directly related to alcohol use disorders, it is not intended to be all inclusive. Several areas, including sleep disorders, pain, and cholinergic anti-inflammatory pathways, are not covered as independent chapters but briefly mentioned in the text. The close relevance of these topics to neural-immune interactions and alcohol use disorders warrants future discussion and more research efforts.

Global Status Report on Alcohol and Health 2018

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9241565632
Total Pages : 472 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Global Status Report on Alcohol and Health 2018 by : World Health Organization

Download or read book Global Status Report on Alcohol and Health 2018 written by World Health Organization and published by World Health Organization. This book was released on 2019-02-14 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The report provides an overview of alcohol consumption and harms in relation to the UN Sustainable Development Goals (Chapter 1) presents global strategies action plans and monitoring frameworks (Chapter 2) gives detailed information on: the consumption of alcohol in populations (Chapter 3); the health consequences of alcohol consumption (Chapter 4); and policy responses at national level (Chapter 5). In its final chapter 6 the imperative for reducing harmful use of alcohol in a public health perspective is presented. In addition the report contains country profiles for WHO Member States and appendices with statistical annexes a description of the data sources and methods used to produce the estimates and references.

Alcohol Research & Health

Author :
Publisher :
ISBN 13 :
Total Pages : 168 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Alcohol Research & Health by :

Download or read book Alcohol Research & Health written by and published by . This book was released on 2002 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Alcohol

Author : George F. Koob
Publisher : Academic Press
ISBN 13 : 0128167947
Total Pages : 402 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Alcohol by : George F. Koob

Download or read book Alcohol written by George F. Koob and published by Academic Press. This book was released on 2021-07-07 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Alcohol, Volume 3 in the series, explores the molecular, cellular, and neurocircuitry systems in the brain responsible for alcohol addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Outlines the history and behavioral mechanism of action of alcohol relevant to the neurobiology of alcohol addiction Includes neurocircuitry, cellular, and molecular neurobiological mechanisms of alcohol addiction in each stage of the addiction cycle Explores evolving areas of research associated with all three stages of the alcohol addiction cycle, including neurobiological studies of neurodevelopmental effects of early exposure to alcohol, sleep disturbances caused by alcohol, pain interactions with alcohol, sex differences in the response to alcohol, and epigenetic/genetic interactions with alcohol

The Gut-Brain Axis

Author : Niall Hyland
Publisher : Academic Press
ISBN 13 : 0128025441
Total Pages : 508 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Gut-Brain Axis by : Niall Hyland

Download or read book The Gut-Brain Axis written by Niall Hyland and published by Academic Press. This book was released on 2016-05-13 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders. Focuses on specific areas in which the microbiota has been implicated in gut-brain communication Examines common mechanisms and pathways by which the microbiota may influence brain and behavior Identifies novel therapeutic strategies targeted toward the microbiota in the management of brain activity and behavior

Perspectives and Recent Advances in Fetal Alcohol Spectrum Disorders Research

Author : Hermes H. Yeh
Publisher : Frontiers Media SA
ISBN 13 : 2832542239
Total Pages : 403 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Perspectives and Recent Advances in Fetal Alcohol Spectrum Disorders Research by : Hermes H. Yeh

Download or read book Perspectives and Recent Advances in Fetal Alcohol Spectrum Disorders Research written by Hermes H. Yeh and published by Frontiers Media SA. This book was released on 2024-01-03 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Genetics of Alcoholism

Author : Henri Begleiter
Publisher : Alcohol and Alcoholism
ISBN 13 : 9780195088779
Total Pages : 420 pages
Book Rating : 4.0/5 (887 download)

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Book Synopsis The Genetics of Alcoholism by : Henri Begleiter

Download or read book The Genetics of Alcoholism written by Henri Begleiter and published by Alcohol and Alcoholism. This book was released on 1995 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspectiveand details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in thedevelopment and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic viewof the knowledge available on the hereditary influences of alcoholism.

Autism Spectrum Disorders: From Genotypes to Phenotypes

Author : Valsamma Eapen
Publisher : Frontiers Media SA
ISBN 13 : 2889196801
Total Pages : 95 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Autism Spectrum Disorders: From Genotypes to Phenotypes by : Valsamma Eapen

Download or read book Autism Spectrum Disorders: From Genotypes to Phenotypes written by Valsamma Eapen and published by Frontiers Media SA. This book was released on 2015-12-10 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic covers the pathogenetic processes in Autism Spectrum Disorder (ASD) that underpin the translation of genetic vulnerability to clinically significant symptoms. Available research data in ASD suggests that it is a neural connectivity disorder and that the social communication and related neurobehavioural symptoms result from reduced synchronization between key "social brain" regions. These interconnected neural systems can be understood through the relationship between functionally relevant anatomic areas and neurochemical pathways, the programming of which are genetically modulated during neurodevelopment and mediated through a range of epigenetic and environmental modulators. Elucidating the underlying molecular mechanisms can provide an invaluable window for understanding the neural wiring that regulates higher brain functions and consequent clinical phenotypes. In keeping with the multi modal and diverse origins of ASD, this Research Topic explores the genetic underpinnings and environmental modulation in the aetiology; neural substrates, biomarkers and endophenotypes that underlie clinical characteristics; as well as neurochemical pathways and pathophysiological mechanisms that pave the way for therapeutic interventions. Furthermore, since genetically mediated deficits and consequent functional impairments involve activity-dependent synapse development that depends on postnatal learning and experience, the trajectory towards the final clinical expression could be modulated by early interventions that exploit the neuronal maturation and brain plasticity. However, identifying these diverse pathogenetic processes and tailoring interventions would require subtyping ASD into homogeneous subgroups. In this regard, this topic covers the current state of evidence in the literature through topic reviews as well as ongoing original work that provides tangible hypotheses and directions for future research.

Neuroimmune Signaling in Drug Actions and Addictions

Author :
Publisher : Academic Press
ISBN 13 : 0128014385
Total Pages : 512 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neuroimmune Signaling in Drug Actions and Addictions by :

Download or read book Neuroimmune Signaling in Drug Actions and Addictions written by and published by Academic Press. This book was released on 2014-08-28 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on Neuroimmune Signaling in Drug Actions and Addictions. This book looks at neuroimmune signaling in drug actions and addictions in the light of the newest scholarly discoveries and insights

Neuroscience of Alcohol

Author : Victor R. Preedy
Publisher : Academic Press
ISBN 13 : 0128131268
Total Pages : 736 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Neuroscience of Alcohol by : Victor R. Preedy

Download or read book Neuroscience of Alcohol written by Victor R. Preedy and published by Academic Press. This book was released on 2019-03-19 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world’s most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of alcohol use, along with its effects on neurobiological function Discusses alcohol use as a component of dual-use and poly addictions Outlines numerous screening and treatment strategies for alcohol misuse Covers both the physical and psychological effects of alcohol use and withdrawals to provide a fully-formed view of alcohol dependency and its effects

Fetal Development

Author : Nadja Reissland
Publisher : Springer
ISBN 13 : 3319220233
Total Pages : 492 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Fetal Development by : Nadja Reissland

Download or read book Fetal Development written by Nadja Reissland and published by Springer. This book was released on 2016-03-15 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of fetal psychobiological research, focusing on brain and behavior, genetic and epigenetic factors affecting both short and long-term development, and technological breakthroughs in the field. These focal points intersect throughout the chapters, as in the challenges of evaluating the fetal central nervous system, the myriad impacts of maternal stressors and resiliencies, and the salience of animal studies. It also discusses specific monitoring and assessment methods, including cardiotocography, biomagnetometry, 4D ultrasound, in utero MRI, and the KANET test. Spanning assessment, identification, and pre- and postnatal intervention, the book weighs the merits of standardized evaluations and argues for more integrative research in the future. Included in the coverage: Effects on the fetus of maternal anxiety, depression, and stress during pregnancy. Clinical and experimental research in human fetuses and animal models. Observational research including the use of behaviors in developing tests to assess fetal health. Fetal auditory processing and implications for language development. Fetal effects of prenatal exposure to selective SRI antidepressant exposure. Structural and functional imaging of the prenatal brain. The effects of alcohol exposure on fetal development. Fetal Development: Research on Brain and Behavior, Environmental Influences, and Emerging Technologies is an essential resource for researchers, clinicians and related professionals, as well as students in a wide range of fields such as developmental psychology, pediatric and obstetrical medicine, neuroscience, nursing, social work, and early childhood education.

Glutamate and Neuropsychiatric Disorders

Author : Zoran M. Pavlovic
Publisher : Springer Nature
ISBN 13 : 303087480X
Total Pages : 623 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Glutamate and Neuropsychiatric Disorders by : Zoran M. Pavlovic

Download or read book Glutamate and Neuropsychiatric Disorders written by Zoran M. Pavlovic and published by Springer Nature. This book was released on 2022-04-10 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive overview of recent advances in targeting glutamate signaling for the treatment of major psychiatric and neurological disorders. It draws on the latest findings in glutamate neurobiology and offers valuable insights into the application of translational principles in neuroscience drug discovery and development. In each chapter, glutamate as a neurotransmitter, its receptors and transporters, and their interplay with other neurotransmitters and neurotrophic factors, are discussed in the context of a specific, highly prevalent and disabling CNS disease. Most recent and detailed information is provided on Ischemic Stroke, Chronic Stress, Major Depressive Disorder, Bipolar Disorder, Autism Spectrum Disorders (ASD), Posttraumatic Stress Disorder (PTSD), Alzheimer’s Dementia, Schizophrenia, Impulsive Aggression, Substance Use Disorders (SUD), Amyotrophic Lateral Sclerosis (ALS), Chronic Pain, Multiple Sclerosis, Parkinson’s Disease, Attention Deficit Hyperactivity Disorder (ADHD), Migraine, Epilepsy and Anxiety disorders. Moreover, the book includes an extensive overview of glutamatergic treatments already available on the market, and those which are currently in pharmaceutical drug development pipelines. The primary beneficiaries will be neurology and psychiatry specialists and residents, neuroscientists, neuropharmacologists, pharmaceutical industry and clinical research organization professionals, academics, and clinicians working with psychiatric and neurological patients with comorbidities such as cardiologists, pulmonologists, and endocrinologists. This book will also appeal to psychiatry and neurology subspecialists and clinicians working in neuroscience labs seeking an easy-to-understand yet comprehensive overview of contemporary evidence-based clinical insights backed by basic science (preclinical) research evidence. Given its scope, the book is also a unique and indispensable resource for both preclinical and clinical neuroscientists, medical advisors, and clinical research specialists in the pharmaceutical industry. In addition, it will appeal to neuroscience and neuropsychopharmacology students and guide them through the complexities of glutamate involvement in the pathophysiology of the most common debilitating brain diseases with high unmet medical needs.

Neuropathology of Drug Addictions and Substance Misuse Volume 1

Author : Victor R. Preedy
Publisher : Academic Press
ISBN 13 : 0128003766
Total Pages : 1132 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neuropathology of Drug Addictions and Substance Misuse Volume 1 by : Victor R. Preedy

Download or read book Neuropathology of Drug Addictions and Substance Misuse Volume 1 written by Victor R. Preedy and published by Academic Press. This book was released on 2016-03-07 with total page 1132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropathology of Drug Addictions and Substance Misuse, Volume One: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids, Opioids and Emerging Addictions provides the latest research in an area that shows that the neuropathological features of one addiction are often applicable to those of others. The book also details how a further understanding of these commonalties can provide a platform for the study of specific addictions in greater depth, all in an effort to create new modes of understanding, causation, prevention, and treatment. The three volumes in this series address new research and challenges, offering comprehensive coverage on the adverse consequences of the most common drugs of abuse, with each volume serving to update the reader’s knowledge on the broader field of addiction, while also deepening our understanding of specific addictive substances. Volume One addresses tobacco, alcohol, cannabinoids, and opioids, with each section providing data on the general, molecular/cellular, and structural/functional neurological aspects of a given substance, along with a focus on the adverse consequences of addictions. Provides a modern approach on the pathology of substances of abuse, offering an evidence based ethos for understanding the neurology of addictions Fills an existing gap in the literature by proving a one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse Includes a list of abbreviations, abstracts, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references in each chapter Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and the genome to whole body

Glucose Homeostasis

Author : Leszek Szablewski
Publisher : BoD – Books on Demand
ISBN 13 : 9535116185
Total Pages : 178 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Glucose Homeostasis by : Leszek Szablewski

Download or read book Glucose Homeostasis written by Leszek Szablewski and published by BoD – Books on Demand. This book was released on 2014-06-18 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most tissues and organs, such as the brain, need glucose constantly, as an important source of energy. The low blood concentrations of glucose (hypoglycemia) can cause seizures, loss of consciousness, and death. On the other hand, long lasting elevation of blood glucose concentrations (hyperglycemia) can result in blindness, renal failure, cardiac and peripheral vascular disease, and neuropathy. Therefore, blood glucose concentrations need to be maintained within narrow limits. The process of maintaining blood glucose at a steady-state level is called glucose homeostasis. This is accomplished by the finely hormone regulation of peripheral glucose uptake (glucose utilization), hepatic glucose production and glucose uptake during carbohydrates ingestion.

Alcohol and the Nervous System

Author : Edith V. Sullivan
Publisher : Elsevier
ISBN 13 : 0444626220
Total Pages : 704 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Alcohol and the Nervous System by : Edith V. Sullivan

Download or read book Alcohol and the Nervous System written by Edith V. Sullivan and published by Elsevier. This book was released on 2014-10-08 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function

Brain Disorders in Critical Illness

Author : Robert D. Stevens
Publisher : Cambridge University Press
ISBN 13 : 1107434424
Total Pages : 457 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis Brain Disorders in Critical Illness by : Robert D. Stevens

Download or read book Brain Disorders in Critical Illness written by Robert D. Stevens and published by Cambridge University Press. This book was released on 2013-09-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.

Advances in Computational Intelligence

Author : Ignacio Rojas
Publisher : Springer
ISBN 13 : 3030205185
Total Pages : 926 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Advances in Computational Intelligence by : Ignacio Rojas

Download or read book Advances in Computational Intelligence written by Ignacio Rojas and published by Springer. This book was released on 2019-06-05 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume set LNCS 10305 and LNCS 10306 constitutes the refereed proceedings of the 15th International Work-Conference on Artificial Neural Networks, IWANN 2019, held at Gran Canaria, Spain, in June 2019. The 150 revised full papers presented in this two-volume set were carefully reviewed and selected from 210 submissions. The papers are organized in topical sections on machine learning in weather observation and forecasting; computational intelligence methods for time series; human activity recognition; new and future tendencies in brain-computer interface systems; random-weights neural networks; pattern recognition; deep learning and natural language processing; software testing and intelligent systems; data-driven intelligent transportation systems; deep learning models in healthcare and biomedicine; deep learning beyond convolution; artificial neural network for biomedical image processing; machine learning in vision and robotics; system identification, process control, and manufacturing; image and signal processing; soft computing; mathematics for neural networks; internet modeling, communication and networking; expert systems; evolutionary and genetic algorithms; advances in computational intelligence; computational biology and bioinformatics.