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Molecular Interactions In Bioseparations
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Book Synopsis Molecular Interactions in Bioseparations by : That T. Ngo
Download or read book Molecular Interactions in Bioseparations written by That T. Ngo and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid advances in molecular biology have accelerated the production of a great number of protein-based therapeutic agents. The major cost in producing these proteins appears to be associated with their purification from the complex mixture of the crude extract. A major challenge to the protein biochemist and the biochemical engineer is the development of rapid, efficient, and cost-effective purification systems. This volume presents state-of-the-art reviews of current methods used in the purifica tion of biological macromolecules that are based on molecular interactions. Thus, the major emphasis is placed on affinity-related techniques. Part I provides a general introduction to affinity chromatography and includes a chapter describing an interesting new technique called "slalom chromatography" for DNA fractionations. Affinity chromatography using molecules of biological origin as the affinity ligand is covered in Part II. Part III describes the use of a special class of biomolecules, antibodies, as affinity ligands. Affinity chromatography with biomimetic ligands is discussed in Part IV. Newer concepts and their applications in bioseparation are presented in Part V. Part VI covers affinity-related techniques such as affinity-based extracorporeal shunts, affinity electrophoresis, affinity precipitation, and affinity extraction. I would like to express my sincere thanks to all the authors, who are recognized experts in their respective fields, for their cooperation and contributions. I thank the editorial staff of Plenum Press for their professionalism, and Mary Phillips Born, Senior Editor, for her encouragement. The support of my family (Ping and Peilin) made it possible to complete editing this book. That T.
Book Synopsis Principles of Bioseparations Engineering by : Raja Ghosh
Download or read book Principles of Bioseparations Engineering written by Raja Ghosh and published by World Scientific Publishing Company. This book was released on 2006-10-23 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioseparations engineering deals with the scientific and engineering principles involved in large-scale separation and purification of biological products. It is a key component of most chemical engineering/biotechnology/bioprocess engineering programmes. This book discusses the underlying principles of bioseparations engineering written from the perspective of an undergraduate course. It covers membrane based bioseparations in much more detail than some of the other books on bioseparations engineering. Based largely on the lecture notes the author developed to teach the course, this book is especially suitable for use as an undergraduate level textbook, as most other textbooks are targeted at graduate students.
Download or read book Bioseparation written by G.T. Tsao and published by Springer. This book was released on 2014-03-12 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bioseparations Science and Engineering by : Roger G. Harrison
Download or read book Bioseparations Science and Engineering written by Roger G. Harrison and published by Oxford University Press. This book was released on 2015-01-27 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for undergraduates, graduate students, and industry practitioners, Bioseparations Science and Engineering fills a critical need in the field of bioseparations. Current, comprehensive, and concise, it covers bioseparations unit operations in unprecedented depth. In each of the chapters, the authors use a consistent method of explaining unit operations, starting with a qualitative description noting the significance and general application of the unit operation. They then illustrate the scientific application of the operation, develop the required mathematical theory, and finally, describe the applications of the theory in engineering practice, with an emphasis on design and scaleup. Unique to this text is a chapter dedicated to bioseparations process design and economics, in which a process simular, SuperPro Designer® is used to analyze and evaluate the production of three important biological products. New to this second edition are updated discussions of moment analysis, computer simulation, membrane chromatography, and evaporation, among others, as well as revised problem sets. Unique features include basic information about bioproducts and engineering analysis and a chapter with bioseparations laboratory exercises. Bioseparations Science and Engineering is ideal for students and professionals working in or studying bioseparations, and is the premier text in the field.
Book Synopsis Downstream Processing and Bioseparation by : Jean-François Hamel
Download or read book Downstream Processing and Bioseparation written by Jean-François Hamel and published by Washington, D.C. : American Chemical Society. This book was released on 1990 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume examines the state of the art of several important separation processes as they relate to biotechnology. Focusing on isolation and purification of downstream processing, it presents recent research results of several promising techniques. Its 15 chapters cover extraction and membrane processing, processes using biospecific interaction with proteins, and novel isolation and purification processes. Many of the chapters contain data that have not been published before. This volume presents the spectrum of current thinking and activities on bioseparation, specifically of large molecules such as proteins and polysaccharides.
Book Synopsis Supramolecular Stereochemistry by : J.S. Siegel
Download or read book Supramolecular Stereochemistry written by J.S. Siegel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the NATO Advanced Research Workshop, Hveragerdi, Iceland, September 14--19, 1994
Book Synopsis Bioseparation Engineering by : I. Endo
Download or read book Bioseparation Engineering written by I. Endo and published by Elsevier. This book was released on 2000-03-17 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bioseparation engineering of today includes downstream process engineering such as waste water, material and gas treatment. Taking this tendency into account, bioseparation engineers gathered in Japan as a special research group under the main theme of "Recovery and Recycle of Resources to Protect the Global Environment". The scope of this book is based on the conference, and deals not only with recent advances in bioseparation engineering in a narrow sence, but also the environmental engineering which includes waste water treatment and bioremediation. The contributors of this book cover many disciplines such as chemical engineering, analytical chemistry, biochemistry, and microbiology. Bioseparation Engineering will stimulate young engineers and scientists who will develop bioseparation engineering further in the 21st century, and contribute to a world-wide attention to the global environment
Book Synopsis Transgenic Plants by : Meran R. L. Owen
Download or read book Transgenic Plants written by Meran R. L. Owen and published by John Wiley & Sons. This book was released on 1997-01-23 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transgenic Plants: A Production System for Industrial andPharmaceutical Proteins provides a detailed guide to the principlesand practice of using transgenic plants as a system for theproduction of heterologous proteins. It is unique in that it coversthe complete process of heterologous protein production in plants,from the initial transformation of the plant, through totranscription, transgene stability and finally the downstreamingprocessing events for protein purification. Written by aninternational team of industrialists and academics, this bookdescribes: * the fundamental issues associated with expressing heterologousproteins in plants; * a number of detailed examples of the successful small-andlarge-scale production of proteins; * the essentials of patenting; and * the commercial exploitation. Transgenic Plants: A Production System for Industrial andPharmaceutical Proteins will be of interest to plantbiotechnologists, molecular biologists and protein biochemists inthe biotechnology and pharmaceutical industries.
Book Synopsis Hplc Of Biological Macro- Molecules, Revised And Expanded by : Karen M. Gooding
Download or read book Hplc Of Biological Macro- Molecules, Revised And Expanded written by Karen M. Gooding and published by CRC Press. This book was released on 2002-01-08 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised to reflect the innovations in HPLC from the past decade, this authoritative reference presents practical strategies for the evaluation and analysis of proteins, peptides, and polynucleotides. Offering class-specific applications for the characterization and fractionation of biological macromolecules, the book contains material on organic supports, size exclusion, ion exchange, hydrophobic interaction, and metal interaction chromatography. Leading experts summarize specialized detection systems, provides discussions on the chemical and biological properties of specific biomolecules, include detailed guidelines for the development of analytical techniques, and more.
Book Synopsis Smart Polymers for Bioseparation and Bioprocessing by : Igor Galaev
Download or read book Smart Polymers for Bioseparation and Bioprocessing written by Igor Galaev and published by CRC Press. This book was released on 2001-11-15 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart polymers are macromolecules capable of undergoing rapid, reversible phase transitions from a hydrophilic to a hydrophobic microstructure when triggered by small changes in their immediate environment, such as slight variations in temperature, pH or ionic strength. Until now, it has always been considered that polymers are passive participants within the Bioseparation procedure. Smart Polymers for Bioseparation and Bioprocessing addresses an entirely novel theory that advocates a much more active role for smart polymers within this process than has previously been envisaged, and therefore focuses on the role of these smart polymers within bioseparation. With contributions from the leading researchers working on smart polymers and their applications, this volume offers a comprehensive overview of both the current state-of-affairs within this research field and the potential for future developments. This book will be of interest to those working on techniques of bioseparation and bioprocessing, polymer chemists developing new smart polymers, as well as graduates in biotechnology.
Book Synopsis Handbook of Bioseparations by : Satinder Ahuja
Download or read book Handbook of Bioseparations written by Satinder Ahuja and published by Elsevier. This book was released on 2000-06-23 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is generally recognized that the commercial success of biotechnology products is highly dependent on the successful development and application of high-powered separation and purification methods. In this practical and authoritative handbook, the separation of proteins, nucleic acids, and oligonucleotides from biological matrices is covered from analytical to process scales. Also included in a chapter on the separation of monoclonal antibodies, which have found numerous uses as therapeutic and diagnostic agents. Analytical techniques include an interesting montage of chromatographic methods, capillary electrophoresis, isoelectric focusing, and mass spectrometry. Among separation and purification methods, liquid-liquid distribution, displacement chromatography, expanded bed adsorption, membrane chromatography, and simulated moving bed chromatography are covered at length. Regulatory and economic considerations are addressed, as are plant and process equipment and engineering process control. A chapter on future developments highlights the application of DNA chip arrays as well as evolving methodologies for a large number of drugs that are under development for treatment of cancer, AIDS, rheumatoid arthritis, and Alzheimer's disease. Handbook of Bioseparations serves as an essential reference and guidebook for separation scientists working in the pharmaceutical and biotechnology industries, academia, and government laboratories. Key Features * Covers bioseparations of proteins, nucleic acids, and monoclonal antibodies * Encompasses both analytical and process-scale methods * Elucidates the importance of engineering process control * Details selection of plant and process equipment * Addresses economic considerations * Discusses future developments
Book Synopsis Liquid Biphasic System by : Pau Loke Show
Download or read book Liquid Biphasic System written by Pau Loke Show and published by Elsevier. This book was released on 2020-11-28 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Downstream bioprocesses have a significant role to play in the creation of a sustainable bio-based economy, enabling the creation of new products and systems from the more sustainable bioprocessing of natural products. Liquid Biphasic System: Fundamentals, Methods, and Applications in Bioseparation Technology explores in detail the fundamental processes and applications of this new separation system, aiding understanding of the basic principles of the technique and offering constructive criticisms on the latest findings. Including coverage of the background, principles, mechanisms, and applications, Liquid Biphasic System addresses how to adapt the technology for the purification of useful compounds with greater cost efficiency and greener processing. It is essential reading for bioprocess engineers, biochemical engineers, biosystem engineers, chemists and microbiologists working in the fields of bioprocessing. Researchers, scientists, and engineers concerned with the selection and evaluation of alternative bioseparation processes will find the book particularly useful. Provides information and examples of advanced separations in a single source Includes detailed descriptions of novel bioseparation systems Covers the latest technologies related to advanced liquid–liquid separation and their applications in various industries
Book Synopsis Separation of Molecules, Macromolecules and Particles by : Kamalesh Sirkar
Download or read book Separation of Molecules, Macromolecules and Particles written by Kamalesh Sirkar and published by Cambridge University Press. This book was released on 2014-01-16 with total page 923 pages. Available in PDF, EPUB and Kindle. Book excerpt: A modern separation process textbook written for advanced undergraduate and graduate level courses in chemical engineering.
Book Synopsis Biochromatography by : M. A. Vijayalakshmi
Download or read book Biochromatography written by M. A. Vijayalakshmi and published by CRC Press. This book was released on 2002-02-14 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of bioseparation, and biochromatography in particular, is advancing very rapidly as our knowledge of the properties of molecules and atomic forces increases. This volume covers the basic principles of biochromatography in detail. It assesses different techniques and includes a large number of applications, providing the reader with a mult
Book Synopsis Bioseparations of Proteins by : Ajit Sadana
Download or read book Bioseparations of Proteins written by Ajit Sadana and published by Elsevier. This book was released on 1997-11-27 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the fundamentals of protein inactivation during bioseparation and the effect on protein processing. Bioseparation of Proteins is unique because it provides a background of the bioseparation processes, and it is the first book available to emphasize the influence of the different bioseparation processes on protein inactivation. Bioseparation of Proteins covers the extent, mechanisms of, and control of protein inactivation during these processes along with the subsequent and essential validation of these processes. The book focuses on the avoidance of protein (biologicalproduct) inactivation at each step in a bioprocess. It compares protein inactivation exhibited during the different bioseparation processes by different workers and provides a valuable framework for workers in different areas interested in bioseparations. Topics include separation and detection methods; estimates of protein inactivation and an analysis of this problem for different separation processes; strategies for avoiding inactivation; the molecular basis of surface activity and protein adsorption,process monitoring, and product validation techniques; and the economics of various bioseparation processes and quality control procedures. Key Features * Protein inactivation and other aspects of biological stability are critical to an effective bioseparation process; This book is a detailed and critical review of the available literature in an area that is essential to the effectiveness, validation, and economics of bioseparation processes for drugs and other biological products; Conveniently assembled under one cover, the survey of the literature and resulting perspective will greatly assist engineers and chemists in designingand improving their own processes; Key features of the text include: * detailed data on biological stability under various bioseparation conditions * extensive case studies from the literature on separation processes, validation, and economics * simplified analysis of protein refolding and inactivation mechanisms * consideration of adsorption theories and the effect of heterogeneity * coverage of both classical and novel bioseparation techniques, including chromatographic procedures
Book Synopsis Microcompartmentation and Phase Separation in Cytoplasm by :
Download or read book Microcompartmentation and Phase Separation in Cytoplasm written by and published by Academic Press. This book was released on 1999-10-21 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume provides an overview of major cytoplasmic properties and events which including cytoarchitecture and the physical properties of cytoplasm, molecular compartmentation and gradients, channeling, sorting, and trafficking. It also addresses physicochemical events, both measured and anticipated, which attend solutions under conditions prevailing in cytoplasm: molecular crowding. It summarizes the current state of knowledge in the field and considers questions such as how molecules in cytoplasm interact.
Download or read book Smart Polymers written by Igor Galaev and published by CRC Press. This book was released on 2007-07-25 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to tackle the application of smart polymers in bioseparation and bioprocessing, Smart Polymers: Applications in Biotechnology and Biomedicine broke new ground in this challenging field. Completely revised, updated, and following in the footsteps of its predecessor, the second edition is poised to take its place as a premier reference in this field. This new edition considers those polymers in which a highly nonlinear response of a smart polymer to small changes in the external medium is of critical importance for the successful functioning of the system. The systems discussed are based on soluble/insoluble transition of smart polymers in aqueous solution, on conformational transitions of the macromolecules physically attached or chemically grafted to a surface and on the shrinking/swelling of covalently cross-linked networks of macromolecules, i.e. smart hydrogels. The book focuses on the theory describing the behavior of smart polymers in solution, as gels, and when grafted to surfaces. It provides solid, quantitative descriptions and reliable guidelines, reflecting the maturation of the field and the demand for the development of new smart polymer systems. The coverage highlights smart gels and especially fast responding and macroporous gels, as these gels pave the way to different applications of smart polymers in the areas ofbioseparation, drug release, and microfluidics. With contributions from leading researchers as well as extensive end-of-chapter references, this volume offers a comprehensive overview of the current state-of-the-art in the field and the potential for future developments.
