Molecular Clocks

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The Molecular Evolutionary Clock

Author : Simon Y. W. Ho
Publisher : Springer Nature
ISBN 13 : 3030601811
Total Pages : 245 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis The Molecular Evolutionary Clock by : Simon Y. W. Ho

Download or read book The Molecular Evolutionary Clock written by Simon Y. W. Ho and published by Springer Nature. This book was released on 2021-01-18 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents coverage of the principles and practice of molecular clocks, which have provided fascinating and unprecedented insights into the evolutionary timescale of life on earth. It begins by following the early development of the molecular evolutionary clock in the 1960s, and leads to the complex statistical approaches that are now used to analyse genome sequences. The chapters of this book have been contributed by leading experts in the field and address the important issues of evolutionary rates, molecular dating, and phylogenomic analysis. This is the first time that these different aspects of the molecular clock have been brought together in a single, comprehensive volume. It is an invaluable reference for students and researchers interested in evolutionary biology, genetic analysis, and genomic evolution.

Telling the Evolutionary Time

Author : Philip C J Donoghue
Publisher : CRC Press
ISBN 13 : 020364252X
Total Pages : 305 pages
Book Rating : 4.2/5 (36 download)

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Book Synopsis Telling the Evolutionary Time by : Philip C J Donoghue

Download or read book Telling the Evolutionary Time written by Philip C J Donoghue and published by CRC Press. This book was released on 2003-12-16 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Determining the precise timing for the evolutionary origin of groups of organisms has become increasingly important as scientists from diverse disciplines attempt to examine rates of anatomical or molecular evolution and correlate intrinsic biological events to extrinsic environmental events. Molecular clock analyses indicate that many major groups

Molecular Clocks

Author : Noah Edward Robinson
Publisher :
ISBN 13 :
Total Pages : 454 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Molecular Clocks by : Noah Edward Robinson

Download or read book Molecular Clocks written by Noah Edward Robinson and published by . This book was released on 2004 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Time for Metabolism and Hormones

Author : Paolo Sassone-Corsi
Publisher : Springer
ISBN 13 : 3319270699
Total Pages : 132 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis A Time for Metabolism and Hormones by : Paolo Sassone-Corsi

Download or read book A Time for Metabolism and Hormones written by Paolo Sassone-Corsi and published by Springer. This book was released on 2016-04-04 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Virus as Populations

Author : Esteban Domingo
Publisher : Academic Press
ISBN 13 : 0128163321
Total Pages : 426 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Virus as Populations by : Esteban Domingo

Download or read book Virus as Populations written by Esteban Domingo and published by Academic Press. This book was released on 2019-11-06 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. Features current views on key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes

Tempo and Mode in Evolution

Author : for the National Academy of Sciences
Publisher : National Academies Press
ISBN 13 : 0309552672
Total Pages : 336 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis Tempo and Mode in Evolution by : for the National Academy of Sciences

Download or read book Tempo and Mode in Evolution written by for the National Academy of Sciences and published by National Academies Press. This book was released on 1995-02-09 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since George Gaylord Simpson published Tempo and Mode in Evolution in 1944, discoveries in paleontology and genetics have abounded. This volume brings together the findings and insights of today's leading experts in the study of evolution, including Ayala, W. Ford Doolittle, and Stephen Jay Gould. The volume examines early cellular evolution, explores changes in the tempo of evolution between the Precambrian and Phanerozoic periods, and reconstructs the Cambrian evolutionary burst. Long-neglected despite Darwin's interest in it, species extinction is discussed in detail. Although the absence of data kept Simpson from exploring human evolution in his book, the current volume covers morphological and genetic changes in human populations, contradicting the popular claim that all modern humans descend from a single woman. This book discusses the role of molecular clocks, the results of evolution in 12 populations of Escherichia coli propagated for 10,000 generations, a physical map of Drosophila chromosomes, and evidence for "hitchhiking" by mutations.

Molecular Biology of Circadian Rhythms

Author : Amita Sehgal
Publisher : John Wiley & Sons
ISBN 13 : 9780471418245
Total Pages : 302 pages
Book Rating : 4.4/5 (182 download)

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Book Synopsis Molecular Biology of Circadian Rhythms by : Amita Sehgal

Download or read book Molecular Biology of Circadian Rhythms written by Amita Sehgal and published by John Wiley & Sons. This book was released on 2004-04 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text begins with a general introduction to biochemical and biophysical aspects of circadian timing, then proceeds to its essential focus on collating the newest information on molecular mechanisms of circadian rhythms. It includes a chapter on the implications for clinical research on affective disorders, sleep disorders, and the relevance for therapeutic treatment, as well as coverage of multiple oscillators and hormonal rhythms. Sections include: Molecular Control of Circadian Rhythms: Animal Models Molecular Control of Circadian Rhythms: From Cyanobacteria to Plants Circadian Organization in Complex Organisms. Chapter topics include examinations of circadian rhythms in non-mammalian vertebrates, neurospora, and humans.

Computational Systems Biology

Author : Andres Kriete
Publisher : Elsevier
ISBN 13 : 9780080459349
Total Pages : 424 pages
Book Rating : 4.4/5 (593 download)

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Book Synopsis Computational Systems Biology by : Andres Kriete

Download or read book Computational Systems Biology written by Andres Kriete and published by Elsevier. This book was released on 2005-11-10 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biology is concerned with the quantitative study of complex biosystems at the molecular, cellular, tissue, and systems scales. Its focus is on the function of the system as a whole, rather than on individual parts. This exciting new arena applies mathematical modeling and engineering methods to the study of biological systems. This book is the first of its kind to focus on the newly emerging field of systems biology with an emphasis on computational approaches. The work covers new concepts, methods for information storage, mining and knowledge extraction, reverse engineering of gene and metabolic networks, as well as modelling and simulation of multi-cellular systems. Central themes include strategies for predicting biological properties and methods for elucidating structure-function relationships.

Matthews' Plant Virology

Author : Richard Ellis Ford Matthews
Publisher : Gulf Professional Publishing
ISBN 13 : 9780123611604
Total Pages : 1084 pages
Book Rating : 4.6/5 (116 download)

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Book Synopsis Matthews' Plant Virology by : Richard Ellis Ford Matthews

Download or read book Matthews' Plant Virology written by Richard Ellis Ford Matthews and published by Gulf Professional Publishing. This book was released on 2002 with total page 1084 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been ten years since the publication of the third edition of this seminal text on plant virology, during which there has been an explosion of conceptual and factual advances. The fourth edition updates and revises many details of the previous editon, while retaining the important older results that constitute the field's conceptual foundation. Key features of the fourth edition include: * Thumbnail sketches of each genera and family groups * Genome maps of all genera for which they are known * Genetic engineered resistance strategies for virus disease control * Latest understanding of virus interactions with plants, including gene silencing * Interactions between viruses and insect, fungal, and nematode vectors * New plate section containing over 50 full-color illustrations.

Encyclopedia of Bioinformatics and Computational Biology

Author :
Publisher : Elsevier
ISBN 13 : 0128114320
Total Pages : 3421 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Bioinformatics and Computational Biology by :

Download or read book Encyclopedia of Bioinformatics and Computational Biology written by and published by Elsevier. This book was released on 2018-08-21 with total page 3421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Encyclopedia of Scientific Dating Methods

Author : W. Jack Rink
Publisher : Springer
ISBN 13 : 9789400763036
Total Pages : 978 pages
Book Rating : 4.7/5 (63 download)

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Book Synopsis Encyclopedia of Scientific Dating Methods by : W. Jack Rink

Download or read book Encyclopedia of Scientific Dating Methods written by W. Jack Rink and published by Springer. This book was released on 2015-08-15 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an overview of (1) the physical and chemical foundations of dating methods and (2) the applications of dating methods in the geological sciences, biology, and archaeology, in almost 200 articles from over 200 international authors. It will serve as the most comprehensive treatise on widely accepted dating methods in the earth sciences and related fields. No other volume has a similar scope, in terms of methods and applications and particularly time range. Dating methods are used to determine the timing and rate of various processes, such as sedimentation (terrestrial and marine), tectonics, volcanism, geomorphological change, cooling rates, crystallization, fluid flow, glaciation, climate change and evolution. The volume includes applications in terrestrial and extraterrestrial settings, the burgeoning field of molecular-clock dating and topics in the intersection of earth sciences with forensics. The content covers a broad range of techniques and applications. All major accepted dating techniques are included, as well as all major datable materials.

The Timetree of Life

Author : S. Blair Hedges
Publisher : OUP Oxford
ISBN 13 : 019160898X
Total Pages : 1237 pages
Book Rating : 4.1/5 (916 download)

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Book Synopsis The Timetree of Life by : S. Blair Hedges

Download or read book The Timetree of Life written by S. Blair Hedges and published by OUP Oxford. This book was released on 2009-04-23 with total page 1237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evolutionary history of life includes two primary components: phylogeny and timescale. Phylogeny refers to the branching order (relationships) of species or other taxa within a group and is crucial for understanding the inheritance of traits and for erecting classifications. However, a timescale is equally important because it provides a way to compare phylogeny directly with the evolution of other organisms and with planetary history such as geology, climate, extraterrestrialimpacts, and other features.The Timetree of Life is the first reference book to synthesize the wealth of information relating to the temporal component of phylogenetic trees. In the past, biologists have relied exclusively upon the fossil record to infer an evolutionary timescale. However, recent revolutionary advances in molecular biology have made it possible to not only estimate the relationships of many groups of organisms, but also to estimate their times of divergence with molecular clocks. The routineestimation and utilization of these so-called 'time-trees' could add exciting new dimensions to biology including enhanced opportunities to integrate large molecular data sets with fossil and biogeographic evidence (and thereby foster greater communication between molecular and traditional systematists). Theycould help estimate not only ancestral character states but also evolutionary rates in numerous categories of organismal phenotype; establish more reliable associations between causal historical processes and biological outcomes; develop a universally standardized scheme for biological classifications; and generally promote novel avenues of thought in many arenas of comparative evolutionary biology.This authoritative reference work brings together, for the first time, experts on all major groups of organisms to assemble a timetree of life. The result is a comprehensive resource on evolutionary history which will be an indispensable reference for scientists, educators, and students in the life sciences, earth sciences, and molecular biology. For each major group of organism, a representative is illustrated and a timetree of families and higher taxonomic groups is shown. Basic aspects ofthe evolutionary history of the group, the fossil record, and competing hypotheses of relationships are discussed. Details of the divergence times are presented for each node in the timetree, and primary literature references are included. The book is complemented by an online database(www.timetree.net) which allows researchers to both deposit and retrieve data.

Molecular Panbiogeography of the Tropics

Author : Michael Heads
Publisher : Univ of California Press
ISBN 13 : 0520951808
Total Pages : 577 pages
Book Rating : 4.5/5 (29 download)

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Book Synopsis Molecular Panbiogeography of the Tropics by : Michael Heads

Download or read book Molecular Panbiogeography of the Tropics written by Michael Heads and published by Univ of California Press. This book was released on 2012-01-04 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular studies reveal highly ordered geographic patterns in plant and animal distributions. The tropics illustrate these patterns of community immobilism leading to allopatric differentiation, as well as other patterns of mobilism, range expansion, and overlap of taxa. Integrating Earth history and biogeography, Molecular Panbiogeography of the Tropics is an alternative view of distributional history in which groups are older than suggested by fossils and fossil-calibrated molecular clocks. The author discusses possible causes for the endemism of high-level taxa in tropical America and Madagascar, and overlapping clades in South America, Africa, and Asia. The book concludes with a critique of adaptation by selection, founded on biogeography and recent work in genetics.

Molecular Evolution and Phylogenetics

Author : Masatoshi Nei
Publisher : Oxford University Press
ISBN 13 : 0199881227
Total Pages : 352 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Molecular Evolution and Phylogenetics by : Masatoshi Nei

Download or read book Molecular Evolution and Phylogenetics written by Masatoshi Nei and published by Oxford University Press. This book was released on 2000-07-27 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.

Molecular Evolution

Author : Roderick D.M. Page
Publisher : John Wiley & Sons
ISBN 13 : 1444313363
Total Pages : 352 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Molecular Evolution by : Roderick D.M. Page

Download or read book Molecular Evolution written by Roderick D.M. Page and published by John Wiley & Sons. This book was released on 2009-07-14 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals. First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution. Chapter summaries and annotated suggestions for further reading. Worked examples facilitate understanding of some of the more complex issues. Emphasis on clarity and accessibility.

The Rhythms Of Life

Author : Leon Kreitzman
Publisher : Profile Books
ISBN 13 : 1847653723
Total Pages : 469 pages
Book Rating : 4.8/5 (476 download)

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Book Synopsis The Rhythms Of Life by : Leon Kreitzman

Download or read book The Rhythms Of Life written by Leon Kreitzman and published by Profile Books. This book was released on 2011-09-30 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Popular science at its most exciting: the breaking new world of chronobiology - understanding the rhythm of life in humans and all plants and animals. The entire natural world is full of rhythms. The early bird catches the worm -and migrates to an internal calendar. Dormice hibernate away the winter. Plants open and close their flowers at the same hour each day. Bees search out nectar-rich flowers day after day. There are cicadas that can breed for only two weeks every 17 years. And in humans: why are people who work anti-social shifts more illness prone and die younger? What is jet-lag and can anything help? Why do teenagers refuse to get up in the morning, and are the rest of us really 'larks' or 'owls'? Why are most people born (and die) between 3am-5am? And should patients be given medicines (and operations) at set times of day, because the body reacts so differently in the morning, evening and at night? The answers lie in our biological clocks the mechanisms which give order to all living things. They impose a structure that enables us to change our behaviour in relation to the time of day, month or year. They are reset at sunrise and sunset each day to link astronomical time with an organism's internal time.

Epigenetics of Aging

Author : Trygve O. Tollefsbol
Publisher : Springer Science & Business Media
ISBN 13 : 1441906398
Total Pages : 469 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Epigenetics of Aging by : Trygve O. Tollefsbol

Download or read book Epigenetics of Aging written by Trygve O. Tollefsbol and published by Springer Science & Business Media. This book was released on 2009-11-11 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.