Molecular Biology of Erythropoiesis

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Publisher : Springer Science & Business Media
ISBN 13 : 146130623X
Total Pages : 227 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Molecular Biology of Erythropoiesis by : Joao L. Ascensao

Download or read book Molecular Biology of Erythropoiesis written by Joao L. Ascensao and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the proceedings of the Fourth Annual Symposium on the Molecular Biology of Hemopoiesis, held in Reno, Nevada, November 1 and 2, 1988. Its focus on erythropoiesis represents an attempt to cover a rapidly expanding field, which has gone from elegant studies of erythro poietin physiology, to molecular biology, to clinical applications and again to physiology. The rapid development has been made possible by cloning of erythropoietin gene and the availability of recombinant hormone. The regulation of heme and its derivatives has also been aided by techniques of molecular biology; there is now a concerted effort to better understand how these enzymes contribute to proliferation, differentiation and maturation of the erythron. Globin gene derrangements have been targets of recent research in an attempt to correct the defect by genetic engineering. In the chapters of this book, several groups "expressed" their views on this subject. Finally, we analyze various regulators of erythropoiesis, both in vivo and in vitro. Dr. Richard Levere was a pioneer in many studies of heme metabolism and of erythropoiesis. He has been a generous supporter of research in this field and of our past meetings. It is only. fitting that this volume should be dedicated to him.

Molecular and Cellular Aspects of Erythropoietin and Erythropoiesis

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Publisher : Springer Science & Business Media
ISBN 13 : 3642726526
Total Pages : 456 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Molecular and Cellular Aspects of Erythropoietin and Erythropoiesis by : Ivan N. Rich

Download or read book Molecular and Cellular Aspects of Erythropoietin and Erythropoiesis written by Ivan N. Rich and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology has provided a tool with which problems in cellular differentiation can be answered. Recombinant DNA technology has been used to obtain quantities of the erythropoietic hormone, erythropoietin. The availability of the hormone has provided a much-needed impetus in learning how erythropoiesis is controlled. Knowledge of the genetic components, transcription and translation of the erythropoietin gene and finally the release of the mature hormone under various physiological conditions should be forthcoming in the near future. This volume will give the reader some indication as to the different aspects of erythropoiesis. They include the regulation of production of the hormone under normal and abnormal conditions, ontogeny and cellular interactions and the assay of the hormone itself.

Erythropoiesis

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Author :
Publisher : Humana
ISBN 13 : 9781493984831
Total Pages : 0 pages
Book Rating : 4.9/5 (848 download)

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Book Synopsis Erythropoiesis by : Joyce A. Lloyd

Download or read book Erythropoiesis written by Joyce A. Lloyd and published by Humana. This book was released on 2018-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume provides thorough protocols describing how to use genetics to study mouse and zebrafish erythropoiesis in whole animal models and for genetically manipulating cultured mouse and human erythroid cells. Protocols include strategies to analyze circulating red blood cell parameters, as well as progenitor cell status, stage of differentiation, and enucleation. Methods for the study of erythroid cell gene regulation using chromatin immunoprecipitation and chromatin conformation capture are detailed. Furthermore, protocols are provided to examine stress erythropoiesis, erythroblastic islands, and erythroblast structure. The collection also includes reviews on the available mouse models of erythropoiesis, as well as on future considerations for good manufacturing practice in order to translate the manufacture of erythrocytes to the clinic. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Erythropoiesis: Methods and Protocols provides a definitive source for molecular and cellular biology protocols to study erythropoiesis and to move this vital field forward.

Molecular, Cellular, and Developmental Biology of Erythropoietin and Erythropoiesis

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Publisher :
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.X/5 (2 download)

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Book Synopsis Molecular, Cellular, and Developmental Biology of Erythropoietin and Erythropoiesis by : Ivan N. Rich

Download or read book Molecular, Cellular, and Developmental Biology of Erythropoietin and Erythropoiesis written by Ivan N. Rich and published by . This book was released on 1994 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recombinant DNA technology has allowed the cloning, sequencing and large-scale production of human erythropoietin, which is now used in therapy for the anaemia of renal disease. In addition, there are many ongoing clinical trials in which recombinant human erythropoietin is being investigated. The availability of the recombinant reagent has added great impetus to all areas of erythropoetin and erythropoiesis research. This multidisciplinary work brings together investigators from many fields who discuss past, present and future research in this area. The science here is primarily experimental and should be of interest to biochemists, experimental haematologists, pharmacologists, clinical haematologists and nephrologists.

Erythropoietins and Erythropoiesis

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Publisher : Springer Science & Business Media
ISBN 13 : 9783764375423
Total Pages : 294 pages
Book Rating : 4.3/5 (754 download)

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Book Synopsis Erythropoietins and Erythropoiesis by : Graham Molineux

Download or read book Erythropoietins and Erythropoiesis written by Graham Molineux and published by Springer Science & Business Media. This book was released on 2005-11-17 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive one-source guide to the most current information on red blood cell formation and the action of recombinant human erythropoietins. Topics covered include: erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia. The newest theories in erythropoiesis (receptors, signaling), manufacturing, new formulations, and clinical research are discussed. The text is ideal for researchers and clinical investigators in academia, biotechnology, and pharmaceutical companies, as well as clinical research associates, clinical monitors, and physician investigators. This softcover volume is an unchanged second printing of the hardcover edition published in 2003.

Erythropoietins, Erythropoietic Factors, and Erythropoiesis

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Publisher : Springer Science & Business Media
ISBN 13 : 3764386983
Total Pages : 337 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Erythropoietins, Erythropoietic Factors, and Erythropoiesis by : Steven G. Elliott

Download or read book Erythropoietins, Erythropoietic Factors, and Erythropoiesis written by Steven G. Elliott and published by Springer Science & Business Media. This book was released on 2009-06-05 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive one-source guide to the most current information on red blood cell formation and the action of recombinant human erythropoietins. Topics covered include: erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia. The newest theories in erythropoiesis (receptors, signaling), manufacturing, new formulations, and clinical research are discussed. The text is ideal for researchers and clinical investigators in academia, biotechnology, and pharmaceutical companies, as well as clinical research associates, clinical monitors, and physician investigators.

Molecular Biology of The Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Basis of Hematopoiesis

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Publisher : Springer Science & Business Media
ISBN 13 : 0387858164
Total Pages : 260 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Molecular Basis of Hematopoiesis by : Amittha Wickrema

Download or read book Molecular Basis of Hematopoiesis written by Amittha Wickrema and published by Springer Science & Business Media. This book was released on 2008-12-26 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although much is known with respect to blood cell formation and function, many new concepts in the areas of the regulation of hematopoietic stem cell commitment and the subsequent survival, proliferation, and differentiation of progenitors have been elucidated in the last five years. Our understanding of the microenvironment where stem cells reside and commit to distinct blood types (the niche) has grown significantly in recent years. Furthermore, blood cells have been used as the key model system to study microRNA function and the role of microRNAs in the transformation of normal cells into cancer cells. The current volume Molecular Basis of Hematopoiesis, edited by Amittha Wickrema & Barbara Kee, provides the most recent developments in the area in addition to a chapter on the utilization of basic science knowledge for the treatment of blood diseases. Each chapter in this book has been written and edited by faculty in major academic and research institutions around the world, who are pushing the frontiers of research in this important area.

In Vitro Aspects of Erythropoiesis

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Publisher : Springer Science & Business Media
ISBN 13 : 1461263018
Total Pages : 558 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis In Vitro Aspects of Erythropoiesis by : M.J. Jr. Murphy

Download or read book In Vitro Aspects of Erythropoiesis written by M.J. Jr. Murphy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: vitro methodology for the cultivation of erythroid The purpose of In Vitro Aspects of Erythropoiesis is to broaden our understanding of the regulation of stem cells. The second series of papers treats cellular normal and neoplastic hematopoietic cells by means and soluble factors which affect erythroid stem cell of a synthesis of different techniques, divergent no differentiation. Hormonal modulation of in vitro menclature as well as a closer standardization of re erythropoiesis is the theme of the third session fol agents and methods which had heretofore produced lowed by a series of papers in the fourth which fo vagaries of results among different laboratories. cuses on erythropoiesis after transformation by ei Hence the papers, discussions and appendices pre ther Friend or Rauscher viruses. The fifth session deals with serum inhibitors to erythropoiesis and the sented in this volume will be of value and interest to investigators and clinicians as well as to students and role of the macrophage in red blood cell production. teachers of hematology. Finally, the sixth session concentrates on the biogen In Vitro Aspects of Erythropoiesis is comprised of esis of erythropoietin in vivo and in vitro. thirty papers delivered by twenty invited contribu Each of the six sections is followed by a discus tors at a three day conference which was held in sion which was transcribed and initially edited at the Capri, Italy in October of 1977. The contributors meeting."

Red Cell Development

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Publisher : Elsevier
ISBN 13 : 0080560946
Total Pages : 290 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Red Cell Development by : James Bieker

Download or read book Red Cell Development written by James Bieker and published by Elsevier. This book was released on 2008-09-12 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compendium provides a concise and up-to-date assessment of critical recent issues related to erythroid biology. Developmental, epigenetic, methodological, biochemical, and clinical aspects are integrated to provide a powerful overview of their interrelationships and importance to the generation of the red cell. The excitement generated by these novel observations and the anticipation of future directions in studies of the red cell is a highlight of this volume. The first comprehensive volume covering the breadth of the topic The latest advancements that lead to novel directions in the study of red cells An informative discussion of red cells as they relate to the essential oxygen-carrying component of the body

Hematopoiesis

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Publisher : Academic Press
ISBN 13 : 0128033266
Total Pages : 310 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Hematopoiesis by :

Download or read book Hematopoiesis written by and published by Academic Press. This book was released on 2016-04-29 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hematopoiesis, the latest volume in the Current Topics in Developmental Biology, covers hematopoiesis, with contributions from an international board of authors. Its chapters provide a comprehensive set of reviews covering such topics as the regulation of blood stem cell development, epigenetic mechanisms controlling erythropoiesis, and regulatory RNAs/HSCs. Covers the area of hematopoiesis International board of authors Provides a comprehensive set of reviews covering such topics as regulation of blood stem cell development, epigenetic mechanisms controlling erythropoiesis, and regulatory RNAs/HSCs

Erythropoiesis: New Insights for the Healthcare Professional: 2011 Edition

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Publisher : ScholarlyEditions
ISBN 13 : 1464906912
Total Pages : 45 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Erythropoiesis: New Insights for the Healthcare Professional: 2011 Edition by :

Download or read book Erythropoiesis: New Insights for the Healthcare Professional: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: Erythropoiesis: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Erythropoiesis in a concise format. The editors have built Erythropoiesis: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Erythropoiesis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Erythropoiesis: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Textbook of Nephro-Endocrinology

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Publisher : Academic Press
ISBN 13 : 0080920462
Total Pages : 534 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Textbook of Nephro-Endocrinology by : Ajay K. Singh

Download or read book Textbook of Nephro-Endocrinology written by Ajay K. Singh and published by Academic Press. This book was released on 2009-01-12 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism. Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field

Molecular Biology of Hematopoiesis 6

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306461361
Total Pages : 434 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Molecular Biology of Hematopoiesis 6 by : Nader G. Abraham

Download or read book Molecular Biology of Hematopoiesis 6 written by Nader G. Abraham and published by Springer Science & Business Media. This book was released on 1999-11-30 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on molecular genetic/drug manipulation affecting the biology of hematopoiesis, leukemia, and other related cancers as well as on hemoglobinopathy, aplastic anemia, pediatric oncology, growth factors in transplantation, hematologic malignancies, solid tumor chemotherapy and drug resistance, gene expression and gene transfer and on viruses and hematopoiesis. Some of the topics covered include: new information on BMT for autoimmune disease and organ transplants, new findings on gene therapy/transfer into HSC, new studies on gene transfer into primates, new information on gene transfer, scientific and clinical results of iron overload and hematopoiesis, iron and erythropoiesis and search for candidate genes, molecular diagnosis and chemotherapy, use of cord blood stem cells for transplantation, and new information on transcriptional factors regulating hematopoiesis.

Erythroid Cells—Advances in Research and Application: 2012 Edition

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Publisher : ScholarlyEditions
ISBN 13 : 1464997764
Total Pages : 312 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Erythroid Cells—Advances in Research and Application: 2012 Edition by :

Download or read book Erythroid Cells—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Erythroid Cells—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Erythroid Cells in a concise format. The editors have built Erythroid Cells—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Erythroid Cells in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Erythroid Cells—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Erythropoietin

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Publisher :
ISBN 13 :
Total Pages : 504 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Erythropoietin by : Allan J. Erslev

Download or read book Erythropoietin written by Allan J. Erslev and published by . This book was released on 1991 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this monograph is to provide an account of the events that led to the transformation of a concept of red cell regulation into an effective treatment of many anemias. Each chapter is authored by investigators who were involved in this transformation and who are still at work on elucidating the origin, kinetics, action, and regulation of this growth hormone. Annotation copyrighted by Book News, Inc., Portland, OR

Erythroid Cells

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Publisher : Springer Science & Business Media
ISBN 13 : 1475795289
Total Pages : 547 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Erythroid Cells by : J. Robin Harris

Download or read book Erythroid Cells written by J. Robin Harris and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series of books, devoted to aspects of blood cell biochemistry, development, immu nology, and ultrastructure, has evolved and separated from the long-established Plenum series Subcellular Biochemistry. It is the intention of these volumes to draw together related areas of investigation and to provide, in the fullness of time, complete coverage of this rapidly advancing important biomedical discipline. Both fundamental and medically applied topics, dealing with normal and pathological cells, will be included. This, the first volume of the series, contains a diverse collection of chapters, all of which relate to erythroid cells. The range of material included is extremely broad and the authors have used contrasting technical approaches, both within their personal experimen tal studies and within their manuscripts. This has led to the production of a very interest ing compilation, which does, nevertheless, possess a strong overall thematic unity. As with all edited volumes, some topics of importance and interest are not included. This may be because of oversight on my part, as editor, or because the authors originally selected failed to submit their manuscript by the agreed-upon submission date. For these omissions I take full responsibility and trust that at least some of the topics omitted, for instance membrane cation transport systems, will be covered within a future volume of the series. This book commences with two chapters of a developmental nature.