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Modulation Of Zinc Release From Bioactive Sol Gel Derived Sio2 Cao Zno Glasses Ceramics And In Vivo Biocompatibility Assessment
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Book Synopsis Modulation of Zinc Release from Bioactive Sol-gel Derived SiO2-CaO-ZnO Glasses & Ceramics and in Vivo Biocompatibility Assessment by : David B. Jaroch
Download or read book Modulation of Zinc Release from Bioactive Sol-gel Derived SiO2-CaO-ZnO Glasses & Ceramics and in Vivo Biocompatibility Assessment written by David B. Jaroch and published by . This book was released on 2006 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Zinc Oxide by Sol–Gel Method for Photoelectrochemical Cells by : Siti Salwa Alias
Download or read book Synthesis of Zinc Oxide by Sol–Gel Method for Photoelectrochemical Cells written by Siti Salwa Alias and published by Springer Science & Business Media. This book was released on 2013-11-20 with total page 59 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the study of synthesized ZnO powder using Zn(CH3COO)2∙2H2O precursor, methanol (as solvent), and sodium hydroxide (NaOH) to vary the pH. The successfully synthesized ZnO powder from the sol-gel centrifugation and sol-gel storage methods were characterized and investigated by X-ray diffraction, field emission scanning electron microscopy, transmission electron microscopy, Fourier-transform infrared spectroscopy, UV–visible spectroscopy, and photoluminescence test to compare the properties of the nanoparticles. The best characteristic of the ZnO powder from both methods was observed when the powders were coated on an ITO glass to fabricate a PEC. The current density–voltage performances of both PECs were investigated under luminescent and dark conditions.
Book Synopsis Synthesis of 60 %CaO Sol-Gel Derived Glass-Ceramic and In Vitro Bioactivity Assessment in SBF Solution by :
Download or read book Synthesis of 60 %CaO Sol-Gel Derived Glass-Ceramic and In Vitro Bioactivity Assessment in SBF Solution written by and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis of Zinc Oxide by Sol-Gel Method for Photoelectrochemical Cells by : Siti Salwa Alias
Download or read book Synthesis of Zinc Oxide by Sol-Gel Method for Photoelectrochemical Cells written by Siti Salwa Alias and published by . This book was released on 2013-11-30 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Preparation and Characterisation of Thermomechanical Properties of Sol-gel Derived Glasses in the PbO-SiO2-B2O3-ZnO System by : Martin Mennig
Download or read book Preparation and Characterisation of Thermomechanical Properties of Sol-gel Derived Glasses in the PbO-SiO2-B2O3-ZnO System written by Martin Mennig and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bio-Glasses written by Julian Jones and published by John Wiley & Sons. This book was released on 2012-05-18 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new work is dedicated to glasses and their variants which can be used as biomaterials to repair diseased and damaged tissues. Bio-glasses are superior to other biomaterials in many applications, such as healing bone by signaling stem cells to become bone cells. Key features: First book on biomaterials to focus on bio-glasses Edited by a leading authority on bio-glasses trained by one of its inventors, Dr Larry Hench Supported by the International Commission on Glass (ICG) Authored by members of the ICG Biomedical Glass Committee, with the goal of creating a seamless textbook Written in an accessible style to facilitate rapid absorption of information Covers all types of glasses, their properties and applications, and demonstrates how glass is an attractive improvement to current procedures Of interest to the biomedical as well as the materials science community. The book covers all types of glasses: traditional glasses, bioactive glasses, sol-gel glasses, phosphate glasses, glass-ceramics, composites and hybrids. Alongside discussion on how bio-glasses are made, their properties, and the reasons for their use, the authors also cover their applications in dentistry, bone regeneration and tissue engineering and cancer treatment. Its solid guidance describes the steps needed to take a new material from concept to clinic, covering the essentials of patenting, scale-up, quality assurance and FDA approval.
Book Synopsis Characterization of Ga2O3-Na2O-CaO-ZnO-SiO2 Bioactive Glasses by : Timothy J. Keenan
Download or read book Characterization of Ga2O3-Na2O-CaO-ZnO-SiO2 Bioactive Glasses written by Timothy J. Keenan and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Synthesis and Evaluation of a ZN-bioactive Glass Series to Prevent Post Operative Infections in Craniofacial Applications by : Kapil Raghuraman
Download or read book Synthesis and Evaluation of a ZN-bioactive Glass Series to Prevent Post Operative Infections in Craniofacial Applications written by Kapil Raghuraman and published by . This book was released on 2018 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinical incidence of large-scale bone defects has increased over the past few decades to both an increasingly aging population and an associated rise in the number of traumatic injuries. These defects require surgical intervention and can be complicated by post-operative surgical site infections; while these infections were originally managed with intravenous antibiotics, overuse of antibiotic drugs in both livestock and hospital environments has contributed to the creation of antibiotic resistant pathogens such as methicillin resistant Staphylococcus aureus. In craniofacial applications, especially, the lack of a synthetic, biocompatible and osteoconductive graft material that could address infections via a non-pharmaceutical approach provided a niche for exploration. The objective of this study was to synthesize a novel glass series, characterize the series to determine whether it would be biologically feasible and if so, identify the antibacterial efficacy and cytocompatibility of the material. A novel Zn-based bioactive glass series was created, as Zn has proven antibacterial capacity in previous studies. Molten mixtures of SiO2, Na2O, SrO, CaO and ZnO with varying CaO and ZnO concentrations, from 0-30% Zn, were quenched in room temperature water and ground to dental cement standards of sub-45 microns. X-ray diffraction revealed broad humps for each composition indicating that each was an amorphous solid. Scanning electron microscopy, energy dispersive spectroscopy and particle size analyses validated that the particle size of each composition was 45 microns, containing a uniform distribution of both large and small particles of the appropriate elemental compositions. BET surface area analysis confirmed that the surface areas of the samples were between 0.4163 m2/g and 0.6671 m2/g from RC-Control to RC-3; similarity in surface areas implied that reactivity differences were likely attributable to other factors. Differential thermal analysis indicated that the glass transition temperature of the series dropped from 635 degrees C to 578 degrees C from RC-Control to RC-3, indicating an increase in reactivity with Zn concentration. This was validated by MAS-NMR where samples shifted from -77ppm for RC-Control, indicating a tendency towards Q1, to -72.1ppm for RC-3, indicating Q0 tendency. The reactivity of the samples was high enough to indicate potential as a bioactive material, and a cement was synthesized with glass powder, polyacrylic acid and DI water at a ratio of 1.3:1 and optimized to working times of ~5min for each glass composition. Co-culture of E. coli with glass powders and subsequent plating onto LB agar revealed that significant antibacterial efficacy was possible for 20% and 30% Zn samples, RC-2 and RC-3. This trend was corroborated when zones of inhibition were measured for cement disks in S. aureus plates. RC-3 had a notably greater antibacterial capacity, but despite this, in a mammalian cell environment with murine MC3T3 pre-osteoblastic cells, showed no cytotoxicity. The antibacterial capacity and cytocompatibility of the RC series is promising and further exploration of RC-3 as an antibacterial bone graft substitute should be conducted.
Book Synopsis Biocompatibility Testing on Zinc-oxide Doped 58s Sol-gel Bioglass by : Markus Krottenthaler
Download or read book Biocompatibility Testing on Zinc-oxide Doped 58s Sol-gel Bioglass written by Markus Krottenthaler and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bioactive Sol-gel Glasses Doped with Cerium, Gallium and Zinc by : Shruti
Download or read book Bioactive Sol-gel Glasses Doped with Cerium, Gallium and Zinc written by Shruti and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Highly Reactive Silver Doped Sol-gel-derived Borate Glasses for Wound Healing Applications by : Shiva Naseri
Download or read book Highly Reactive Silver Doped Sol-gel-derived Borate Glasses for Wound Healing Applications written by Shiva Naseri and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Bioactive and soluble glasses exhibit great potential in biomedical applications in both hard and soft tissue engineering. The rate at which these glasses generate a response, or their reactivity, is an important parameter for healing efficacy. Owing to their tetrahedral coordination, silicate-based glasses exhibit slow and incomplete solubility, which limit their application in soft tissue repair. Therefore, there is great interest in developing more soluble and reactive bioactive glass formulations based on the borate network forming oxide, which can be both trigonally and tetrahedrally coordinated. It has been shown that borate-based glasses have higher reactivity than silicate-based glasses attributed to their glass network structure. Limitations in conventional methods such as the lack of accuracy and time-consumption to examine reactivity/bioactivity and surface properties of bioactive and soluble glasses have led to an increased interest in finding and investigating new techniques, such as dynamic vapour sorption (DVS) and inverse gas chromatography (IGC). It was demonstrated that DVS has the ability to measure and predict the bioactivity/reactivity of silicate-, phosphate- and borate- based glasses with various specific surface areas/particle sizes or formulations. It was shown that DVS was able to measure and correlate the vapour isotherm values of melt-quench derived Bioglass® 45S5: (46.1)SiO2-(26.9)CaO-(24.4)Na2O-(2.6)P2O5 (mol %) of three different particle sizes (surface areas) with the reactivity, bioactivity and ions release rates of glasses. Higher surface area led to the higher vapour sorption and reactivity. Additionally, IGC was utilized to examine the surface properties of melt-quench derived phosphate glasses (PGs) doped with both SiO2 and TiO2 (50P2O5-40CaO-xSiO2-(10 − x) TiO2, where x = 7, 5, 3, and 0 mol%). It was shown that IGC was more accurate and sensitive than other conventional techniques such as contact angle measurement in determining the effect of silica content on the surface properties of PGs. In conclusion, this dissertation has assessed the potential complementarity of DVS and IGC in the characterization of aqueous reactivity and surface properties of bioactive and soluble glasses.Moreover, complications in the healing of chronic wounds in patients who are at constant risk of infections have led to a great demand for the development of biomaterial based wound dressing replacement. Borate-based glasses have recently been approved for wound repair which are melt-quench derived, yet borate glasses fabricated through the sol-gel process have the benefits of higher dissolution rate, which could potentially lead to the more rapid wound repair. However, the potential of sol-gel derived borate glasses, in particular, silver doped borate-based glasses (AgBGs) for soft tissue repair has so far not been investigated. In this thesis, anti-bacterial AgBGs in the B2O3Ag2O-CaO-P2O5 system were fabricated through optimization of sol-gel process and glass composition. Silver ion release rate and anti-bacterial activity were correlated and demonstrated dose dependent efficacy against Escherichia coli or Staphylococcus aureus and Pseudomonas aeruginosa bacteria. In addition, AgBGs were systematically examined to determine their effects on cellular functions such as metabolic activity, cell viability and migration through in vitro cell culture of human derived keratinocyte (HaCat) and mouse derived fibroblastic (NIH/3T3) cell lines. It was verified that silver release from AgBGs was not toxic to both cells at lower concentrations (
Book Synopsis Low Temperature Synthesis of CaO-SiO2 Glasses Having Stable Liquid-liquid Immiscibility by Sol-gel Process by :
Download or read book Low Temperature Synthesis of CaO-SiO2 Glasses Having Stable Liquid-liquid Immiscibility by Sol-gel Process written by and published by . This book was released on 1990 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunomodulatory Biomaterials by : Stephen F. Badylak
Download or read book Immunomodulatory Biomaterials written by Stephen F. Badylak and published by Woodhead Publishing. This book was released on 2021-07-30 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an "inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. - Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response - Provides a single reference for understanding and utilizing the host response in biomaterials design - An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area
Book Synopsis An Introduction to Tissue-Biomaterial Interactions by : Kay C. Dee
Download or read book An Introduction to Tissue-Biomaterial Interactions written by Kay C. Dee and published by John Wiley & Sons. This book was released on 2003-04-14 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Tissue-Biomaterial Interactions acquaints an undergraduate audience with the fundamental biological processes that influence these sophisticated, cutting-edge procedures. Chapters one through three provide more detail about the molecular-level events that happen at the tissue-implant interface, while chapters four through ten explore selected material, biological, and physiological consequences of these events. The importance of the body’s wound-healing response is emphasized throughout. Specific topics covered include:Structure and properties of biomaterials Proteins Protein-surface interactions Blood-biomaterial interactions Inflammation and infection The immune system Biomaterial responses to implantation Biomaterial surface engineering Intimal hyperplasia and osseointegration as examples of tissue-biomaterial interactions The text also provides extensive coverage of the three pertinent interfaces between the body and the biomaterial, between the body and the living cells, and between the cells and the biomaterial that are critical in the development of tissue-engineered products that incorporate living cells within a biomaterial matrix. Ideal for a one-semester, biomedical engineering course, An Introduction to Tissue-Biomaterial Interactions provides a solid framework for understanding today’s and tomorrow’s implantable biomedical devices.
Book Synopsis Synthesis, Characterization and Investigation on Biomineralization of 86s and 70s30c Sol-gel Derived Bioactive Glass by : Siew Li Lee
Download or read book Synthesis, Characterization and Investigation on Biomineralization of 86s and 70s30c Sol-gel Derived Bioactive Glass written by Siew Li Lee and published by . This book was released on 2016 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Multifunctional SiO2-CaO Based Mesoporous Bioactive Glasses with Therapeutic Ion and Biomolecule Releasing Capability by : Qaisar Nawaz
Download or read book Multifunctional SiO2-CaO Based Mesoporous Bioactive Glasses with Therapeutic Ion and Biomolecule Releasing Capability written by Qaisar Nawaz and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis PEEK Biomaterials Handbook by : Steven M. Kurtz
Download or read book PEEK Biomaterials Handbook written by Steven M. Kurtz and published by William Andrew. This book was released on 2011-11-09 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: PEEK biomaterials are currently used in thousands of spinal fusion patients around the world every year. Durability, biocompatibility and excellent resistance to aggressive sterilization procedures make PEEK a polymer of choice, replacing metal in orthopedic implants, from spinal implants and hip replacements to finger joints and dental implants. This Handbook brings together experts in many different facets related to PEEK clinical performance as well as in the areas of materials science, tribology, and biology to provide a complete reference for specialists in the field of plastics, biomaterials, medical device design and surgical applications. Steven Kurtz, author of the well respected UHMWPE Biomaterials Handbook and Director of the Implant Research Center at Drexel University, has developed a one-stop reference covering the processing and blending of PEEK, its properties and biotribology, and the expanding range of medical implants using PEEK: spinal implants, hip and knee replacement, etc. Covering materials science, tribology and applications Provides a complete reference for specialists in the field of plastics, biomaterials, biomedical engineering and medical device design and surgical applications
