Introduction to Modeling in Physiology and Medicine

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Author :
Publisher : Elsevier
ISBN 13 : 0080559980
Total Pages : 337 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Introduction to Modeling in Physiology and Medicine by : Claudio Cobelli

Download or read book Introduction to Modeling in Physiology and Medicine written by Claudio Cobelli and published by Elsevier. This book was released on 2008-02-06 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unified modeling textbook for students of biomedical engineering provides a complete course text on the foundations, theory and practice of modeling and simulation in physiology and medicine. It is dedicated to the needs of biomedical engineering and clinical students, supported by applied BME applications and examples. Developed for biomedical engineering and related courses: speaks to BME students at a level and in a language appropriate to their needs, with an interdisciplinary clinical/engineering approach, quantitative basis, and many applied examples to enhance learning Delivers a quantitative approach to modeling and also covers simulation: the perfect foundation text for studies across BME and medicine Extensive case studies and engineering applications from BME, plus end-of-chapter exercises

Introduction to Modeling in Physiology and Medicine

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Author :
Publisher : Academic Press
ISBN 13 : 0128158050
Total Pages : 384 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Introduction to Modeling in Physiology and Medicine by : Claudio Cobelli

Download or read book Introduction to Modeling in Physiology and Medicine written by Claudio Cobelli and published by Academic Press. This book was released on 2019-08-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Modeling in Physiology and Medicine, Second Edition, develops a clear understanding of the fundamental principles of good modeling methodology. Sections show how to create valid mathematical models that are fit for a range of purposes. These models are supported by detailed explanation, extensive case studies, examples and applications. This updated edition includes clearer guidance on the mathematical prerequisites needed to achieve the maximum benefit from the material, a greater detail regarding basic approaches to modeling, and discussions on non-linear and stochastic modeling. The range of case study material has been substantially extended, with examples drawn from recent research experience. Key examples include a cellular model of insulin secretion and its extension to the whole-body level, a model of insulin action during a meal/oral glucose tolerance test, a large-scale simulation model of type 1 diabetes and its use in in silico clinical trials and drug trials. Covers the underlying principles of good quantitative modeling methodology, with applied biomedical engineering and bioscience examples to ensure relevance to students, current research and clinical practice Includes modeling data, modeling systems, linear and non-linear systems, model identification, parametric and non-parametric models, and model validation Presents clear, step-by-step working plus examples and extensive case studies that relate concepts to real world applications Provides end-of-chapter exercises and assignments to reinforce learning

Modelling Methodology for Physiology and Medicine

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Author :
Publisher : Newnes
ISBN 13 : 0124095259
Total Pages : 589 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Modelling Methodology for Physiology and Medicine by : Ewart Carson

Download or read book Modelling Methodology for Physiology and Medicine written by Ewart Carson and published by Newnes. This book was released on 2013-12-05 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modelling Methodology for Physiology and Medicine, Second Edition, offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modeling methodology that is widely applicable to physiology and medicine. The second edition, which is completely updated and expanded, opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. The focus of Modelling Methodology for Physiology and Medicine, Second Edition, is the methodology that underpins good modeling practice. It builds upon the idea of an integrated methodology for the development and testing of mathematical models. It covers many specific areas of methodology in which important advances have taken place over recent years and illustrates the application of good methodological practice in key areas of physiology and medicine. It builds on work that the editors have carried out over the past 30 years, working in cooperation with leading practitioners in the field. Builds upon and enhances the reader's existing knowledge of modeling methodology and practice Editors are internationally renowned leaders in their respective fields Provides an understanding of modeling methodologies that can address real problems in physiology and medicine and achieve results that are beneficial either in advancing research or in providing solutions to clinical problems

Mathematical Modeling and Validation in Physiology

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Author :
Publisher : Springer
ISBN 13 : 3642328822
Total Pages : 270 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Mathematical Modeling and Validation in Physiology by : Jerry J. Batzel

Download or read book Mathematical Modeling and Validation in Physiology written by Jerry J. Batzel and published by Springer. This book was released on 2012-12-14 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume synthesizes theoretical and practical aspects of both the mathematical and life science viewpoints needed for modeling of the cardiovascular-respiratory system specifically and physiological systems generally. Theoretical points include model design, model complexity and validation in the light of available data, as well as control theory approaches to feedback delay and Kalman filter applications to parameter identification. State of the art approaches using parameter sensitivity are discussed for enhancing model identifiability through joint analysis of model structure and data. Practical examples illustrate model development at various levels of complexity based on given physiological information. The sensitivity-based approaches for examining model identifiability are illustrated by means of specific modeling examples. The themes presented address the current problem of patient-specific model adaptation in the clinical setting, where data is typically limited.

Physics, Pharmacology and Physiology for Anaesthetists

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1107615887
Total Pages : 439 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Physics, Pharmacology and Physiology for Anaesthetists by : Matthew E. Cross

Download or read book Physics, Pharmacology and Physiology for Anaesthetists written by Matthew E. Cross and published by Cambridge University Press. This book was released on 2014-03-06 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams.

Applied Mathematical Models in Human Physiology

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Publisher : SIAM
ISBN 13 : 9780898718287
Total Pages : 311 pages
Book Rating : 4.7/5 (182 download)

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Book Synopsis Applied Mathematical Models in Human Physiology by : Johnny T. Ottesen

Download or read book Applied Mathematical Models in Human Physiology written by Johnny T. Ottesen and published by SIAM. This book was released on 2004-01-01 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces mathematicians to real applications from physiology. Using mathematics to analyze physiological systems, the authors focus on models reflecting current research in cardiovascular and pulmonary physiology. In particular, they present models describing blood flow in the heart and the cardiovascular system, as well as the transport of oxygen and carbon dioxide through the respiratory system and a model for baroreceptor regulation.

Modeling Physiology of Crop Development, Growth and Yield

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Author :
Publisher : CABI
ISBN 13 : 9781845939717
Total Pages : 322 pages
Book Rating : 4.9/5 (397 download)

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Book Synopsis Modeling Physiology of Crop Development, Growth and Yield by : Afshin Soltani

Download or read book Modeling Physiology of Crop Development, Growth and Yield written by Afshin Soltani and published by CABI. This book was released on 2012-01-01 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Model studies focus experimental investigations to improve our understanding and performance of systems. Concentrating on crop modelling, this book provides an introduction to the concepts of crop development, growth, and yield, with step-by-step outlines to each topic, suggested exercises and simple equations. A valuable text for students and researchers of crop development alike, this book is written in five parts that allow the reader to develop a solid foundation and coverage of production models including water- and nitrogen-limited systems.

Mathematical Modeling in Renal Physiology

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Publisher : Springer
ISBN 13 : 364227367X
Total Pages : 225 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Mathematical Modeling in Renal Physiology by : Anita T. Layton

Download or read book Mathematical Modeling in Renal Physiology written by Anita T. Layton and published by Springer. This book was released on 2014-08-06 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the availability of high speed computers and advances in computational techniques, the application of mathematical modeling to biological systems is expanding. This comprehensive and richly illustrated volume provides up-to-date, wide-ranging material on the mathematical modeling of kidney physiology, including clinical data analysis and practice exercises. Basic concepts and modeling techniques introduced in this volume can be applied to other areas (or organs) of physiology. The models presented describe the main homeostatic functions performed by the kidney, including blood filtration, excretion of water and salt, maintenance of electrolyte balance and regulation of blood pressure. Each chapter includes an introduction to the basic relevant physiology, a derivation of the essential conservation equations and then a discussion of a series of mathematical models, with increasing level of complexity. This volume will be of interest to biological and mathematical scientists, as well as physiologists and nephrologists, who would like an introduction to mathematical techniques that can be applied to renal transport and function. The material is written for students who have had college-level calculus, but can be used in modeling courses in applied mathematics at all levels through early graduate courses.

Mathematical Physiology

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Publisher : Springer Science & Business Media
ISBN 13 : 038775847X
Total Pages : 1067 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Mathematical Physiology by : James Keener

Download or read book Mathematical Physiology written by James Keener and published by Springer Science & Business Media. This book was released on 2010-06-04 with total page 1067 pages. Available in PDF, EPUB and Kindle. Book excerpt: Divided into two volumes, the book begins with a pedagogical presentation of some of the basic theory, with chapters on biochemical reactions, diffusion, excitability, wave propagation and cellular homeostasis. The second, more extensive part discusses particular physiological systems, with chapters on calcium dynamics, bursting oscillations and secretion, cardiac cells, muscles, intercellular communication, the circulatory system, the immune system, wound healing, the respiratory system, the visual system, hormone physiology, renal physiology, digestion, the visual system and hearing. New chapters on Calcium Dynamics, Neuroendocrine Cells and Regulation of Cell Function have been included. Reviews from first edition: Keener and Sneyd's Mathematical Physiology is the first comprehensive text of its kind that deals exclusively with the interplay between mathematics and physiology. Writing a book like this is an audacious act! -Society of Mathematical Biology Keener and Sneyd's is unique in that it attempts to present one of the most important subfields of biology and medicine, physiology, in terms of mathematical "language", rather than organizing materials around mathematical methodology. -SIAM review

Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology

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Author :
Publisher : McGraw Hill Professional
ISBN 13 : 0071714464
Total Pages : 216 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology by : Willem L. van Meurs

Download or read book Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology written by Willem L. van Meurs and published by McGraw Hill Professional. This book was released on 2011-08-07 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation. A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications. Coverage includes: Signals and systems Model requirements Conceptual models Mathematical models Software implementation Simulation results and model validation Cardiorespiratory system model Circulation Respiration Physiologic control Sensitivity analysis of a cardiovascular model Design of model-driven acute care training simulators “Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). ...His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. ...The ample illustrations and tables also break up the text and make reading the book easier on the eyes. ...concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all these topics together under one cover and is an important contribution to biomedical literature.” --IEEE Pulse, January 2014 “This book is written by a professional engineer who is unique in that he seems to have a natural understanding of 3 key areas as follows: the hardware involved with simulators, human physiology, and mathematical modeling. Willem van Meurs is one of the inventors of the model-driven human patient simulator (HPS), and so, he is very qualified to write this book. The book is written in a clear way, using the first person throughout, in a conversational manner, with a style that involves posing questions and answering them in subsequent text. ...The book starts with a very useful introduction and background chapter, setting out the scene for the rest of the book. ...I have used his book in enhancing my own talks and understanding human patient simulation and can strongly recommend it.” --Simulation in Healthcare December, 2012 Reviewed by Mark A. Tooley, Ph.D., Department of Medical Physics and Bioengineering, Royal United Hospital, Combe Park, Bath, UK.

Biomedical Modeling and Simulation on a PC

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Publisher : Springer Science & Business Media
ISBN 13 : 1461391636
Total Pages : 533 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Biomedical Modeling and Simulation on a PC by : Rogier P.van Wijk van Brievingh

Download or read book Biomedical Modeling and Simulation on a PC written by Rogier P.van Wijk van Brievingh and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: I have long had an interest in the life sciences, but have had few opportunities to indulge that interest in my professional activities. It has only been through simulation that those opportunities have arisen. Some of my most enjoyable classes were those I taught to students in the life sciences, where I attempted to show them the value of simulation to their discipline. That there is such a value cannot be questioned. Whether you are interested in population ecology, phar macokinetics, the cardiovascular system, or cell interaction, simulation can play a vital role in explaining the underlying processes and in enhancing our understanding of these processes. This book comprises an excellent collection of contributions, and clearly demonstrates the value of simulation in the particular areas of physiology and bioengineering. My main frustration when teaching these classes to people with little or no computer background was the lack of suitable simulation software. This di rectly inspired my own attempts at producing software usable by the computer novice. It is especially nice that software is available that enables readers to experience the examples in this book for themselves. I would like to congratulate and thank the editors, Rogier P. van Wijk van Brievingh and Dietmar P. P. Moller, for all of their excellent efforts. They should be proud of their achievement. This is the sixth volume in the Advances in Simulation series, and other volumes are in preparation.

Applied Mathematical Models in Human Physiology

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Publisher : SIAM
ISBN 13 : 0898715393
Total Pages : 304 pages
Book Rating : 4.8/5 (987 download)

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Book Synopsis Applied Mathematical Models in Human Physiology by : Johnny T. Ottesen

Download or read book Applied Mathematical Models in Human Physiology written by Johnny T. Ottesen and published by SIAM. This book was released on 2004-02-01 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces mathematicians to real applications from physiology. Using mathematics to analyze physiological systems, the authors discuss models reflecting current research in cardiovascular and pulmonary physiology. In particular, they present models describing blood flow in the heart and the cardiovascular system, as well as the transport of oxygen and carbon dioxide through the respiratory system and a model for baroreceptor regulation. This is the only book available that analyzes up-to-date models of the physiological system at several levels of detail; both simple 'real-time' models that can be directly used in larger systems, and more detailed 'reference' models that show the underlying physiological mechanisms and provide parameters for and validation of simpler models. The book also covers two-dimensional modeling of the fluid dynamics in the heart and its ability to pump, and includes a discussion of modeling wave-propagation throughout the systemic arteries.

Advanced Methods of Physiological System Modeling

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (919 download)

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Book Synopsis Advanced Methods of Physiological System Modeling by : Vasilis Z. Marmarelis

Download or read book Advanced Methods of Physiological System Modeling written by Vasilis Z. Marmarelis and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Modeling of Physiological Flows

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Publisher : Springer Science & Business Media
ISBN 13 : 8847019354
Total Pages : 418 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Modeling of Physiological Flows by : Davide Ambrosi

Download or read book Modeling of Physiological Flows written by Davide Ambrosi and published by Springer Science & Business Media. This book was released on 2012-10-31 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a mathematical update of the state of the art of the research in the field of mathematical and numerical models of the circulatory system. It is structured into different chapters, written by outstanding experts in the field. Many fundamental issues are considered, such as: the mathematical representation of vascular geometries extracted from medical images, modelling blood rheology and the complex multilayer structure of the vascular tissue, and its possible pathologies, the mechanical and chemical interaction between blood and vascular walls, and the different scales coupling local and systemic dynamics. All of these topics introduce challenging mathematical and numerical problems, demanding for advanced analysis and efficient simulation techniques, and pay constant attention to applications of relevant clinical interest. This book is addressed to graduate students and researchers in the field of bioengineering, applied mathematics and medicine, wishing to engage themselves in the fascinating task of modeling the cardiovascular system or, more broadly, physiological flows.

Mathematical and Computer Modeling of Physiological Systems

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Publisher :
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Mathematical and Computer Modeling of Physiological Systems by : Vincent C. Rideout

Download or read book Mathematical and Computer Modeling of Physiological Systems written by Vincent C. Rideout and published by . This book was released on 1991 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nonlinear Dynamic Modeling of Physiological Systems

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Publisher : John Wiley & Sons
ISBN 13 : 9780471469605
Total Pages : 564 pages
Book Rating : 4.4/5 (696 download)

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Book Synopsis Nonlinear Dynamic Modeling of Physiological Systems by : Professor Vasilis Z. Marmarelis

Download or read book Nonlinear Dynamic Modeling of Physiological Systems written by Professor Vasilis Z. Marmarelis and published by John Wiley & Sons. This book was released on 2004-09-03 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of nonlinearities in physiology has been hindered by the lack of effective ways to obtain nonlinear dynamic models from stimulus-response data in a practical context. A considerable body of knowledge has accumulated over the last thirty years in this area of research. This book summarizes that progress, and details the most recent methodologies that offer practical solutions to this daunting problem. Implementation and application are discussed, and examples are provided using both synthetic and actual experimental data. This essential study of nonlinearities in physiology apprises researchers and students of the latest findings and techniques in the field.

Advanced Methods of Physiological System Modeling

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Publisher : Springer Science & Business Media
ISBN 13 : 1475790244
Total Pages : 276 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Advanced Methods of Physiological System Modeling by : V.Z. Marmarelis

Download or read book Advanced Methods of Physiological System Modeling written by V.Z. Marmarelis and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the third in a series entitled" Advanced Methods of Physiological System Modeling" and the fifth in a series of research volumes published by Plenum under the sponsorship of the Biomedical Simulations Resource (BMSR) at the Uni versity of Southern California in the context of dissemination activities supported by the Biomedical Research Technology Program of the National Center for Research Resources at the National Institutes of Health under Grant No. P41 RR-OI861. These volumes are edited by BMSR principal scientists and report on recent research de velopments in the area of physiological systems modeling, as well as on advanced methods for analysis of physiological signals and data. As in the previous two volumes of this series, the work reported herein is con cerned with the development of advanced modeling methodologies and their novel application to problems of biomedical interest, with emphasis on nonlinear aspects of physiological function. The term "advanced methodologies" is used to indicate that the scope of this work extends beyond the ordinary type of analysis, which is confined traditionally to the linear domain. As the importance of nonlinearities in understanding the complex mechanisms of physiological function is increasingly recognized, the need for effective and practical modeling methodologies that address the issue of nonlinear dynamics in life sciences becomes more and more pressing.