Medical Information Extraction And Analysis

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Secondary Analysis of Electronic Health Records

Author : MIT Critical Data
Publisher : Springer
ISBN 13 : 3319437429
Total Pages : 435 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Secondary Analysis of Electronic Health Records by : MIT Critical Data

Download or read book Secondary Analysis of Electronic Health Records written by MIT Critical Data and published by Springer. This book was released on 2016-09-09 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.

Registries for Evaluating Patient Outcomes

Author : Agency for Healthcare Research and Quality/AHRQ
Publisher : Government Printing Office
ISBN 13 : 1587634333
Total Pages : 385 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Registries for Evaluating Patient Outcomes by : Agency for Healthcare Research and Quality/AHRQ

Download or read book Registries for Evaluating Patient Outcomes written by Agency for Healthcare Research and Quality/AHRQ and published by Government Printing Office. This book was released on 2014-04-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.

Statistics and Machine Learning Methods for EHR Data

Author : Hulin Wu
Publisher : CRC Press
ISBN 13 : 1000260941
Total Pages : 329 pages
Book Rating : 4.0/5 (2 download)

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Book Synopsis Statistics and Machine Learning Methods for EHR Data by : Hulin Wu

Download or read book Statistics and Machine Learning Methods for EHR Data written by Hulin Wu and published by CRC Press. This book was released on 2020-12-09 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of Electronic Health Records (EHR)/Electronic Medical Records (EMR) data is becoming more prevalent for research. However, analysis of this type of data has many unique complications due to how they are collected, processed and types of questions that can be answered. This book covers many important topics related to using EHR/EMR data for research including data extraction, cleaning, processing, analysis, inference, and predictions based on many years of practical experience of the authors. The book carefully evaluates and compares the standard statistical models and approaches with those of machine learning and deep learning methods and reports the unbiased comparison results for these methods in predicting clinical outcomes based on the EHR data. Key Features: Written based on hands-on experience of contributors from multidisciplinary EHR research projects, which include methods and approaches from statistics, computing, informatics, data science and clinical/epidemiological domains. Documents the detailed experience on EHR data extraction, cleaning and preparation Provides a broad view of statistical approaches and machine learning prediction models to deal with the challenges and limitations of EHR data. Considers the complete cycle of EHR data analysis. The use of EHR/EMR analysis requires close collaborations between statisticians, informaticians, data scientists and clinical/epidemiological investigators. This book reflects that multidisciplinary perspective.

Neural Network Methods in Natural Language Processing

Author : Yoav Goldberg
Publisher : Morgan & Claypool Publishers
ISBN 13 : 162705295X
Total Pages : 311 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Neural Network Methods in Natural Language Processing by : Yoav Goldberg

Download or read book Neural Network Methods in Natural Language Processing written by Yoav Goldberg and published by Morgan & Claypool Publishers. This book was released on 2017-04-17 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural networks are a family of powerful machine learning models and this book focuses on their application to natural language data. The first half of the book (Parts I and II) covers the basics of supervised machine learning and feed-forward neural networks, the basics of working with machine learning over language data, and the use of vector-based rather than symbolic representations for words. It also covers the computation-graph abstraction, which allows to easily define and train arbitrary neural networks, and is the basis behind the design of contemporary neural network software libraries. The second part of the book (Parts III and IV) introduces more specialized neural network architectures, including 1D convolutional neural networks, recurrent neural networks, conditioned-generation models, and attention-based models. These architectures and techniques are the driving force behind state-of-the-art algorithms for machine translation, syntactic parsing, and many other applications. Finally, we also discuss tree-shaped networks, structured prediction, and the prospects of multi-task learning.

Clinical Text Mining

Author : Hercules Dalianis
Publisher : Springer
ISBN 13 : 3319785036
Total Pages : 192 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Clinical Text Mining by : Hercules Dalianis

Download or read book Clinical Text Mining written by Hercules Dalianis and published by Springer. This book was released on 2018-05-14 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book describes the results of natural language processing and machine learning methods applied to clinical text from electronic patient records. It is divided into twelve chapters. Chapters 1-4 discuss the history and background of the original paper-based patient records, their purpose, and how they are written and structured. These initial chapters do not require any technical or medical background knowledge. The remaining eight chapters are more technical in nature and describe various medical classifications and terminologies such as ICD diagnosis codes, SNOMED CT, MeSH, UMLS, and ATC. Chapters 5-10 cover basic tools for natural language processing and information retrieval, and how to apply them to clinical text. The difference between rule-based and machine learning-based methods, as well as between supervised and unsupervised machine learning methods, are also explained. Next, ethical concerns regarding the use of sensitive patient records for research purposes are discussed, including methods for de-identifying electronic patient records and safely storing patient records. The book’s closing chapters present a number of applications in clinical text mining and summarise the lessons learned from the previous chapters. The book provides a comprehensive overview of technical issues arising in clinical text mining, and offers a valuable guide for advanced students in health informatics, computational linguistics, and information retrieval, and for researchers entering these fields.

Artificial Intelligence in Healthcare

Author : Adam Bohr
Publisher : Academic Press
ISBN 13 : 0128184396
Total Pages : 385 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Artificial Intelligence in Healthcare by : Adam Bohr

Download or read book Artificial Intelligence in Healthcare written by Adam Bohr and published by Academic Press. This book was released on 2020-06-21 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. - Highlights different data techniques in healthcare data analysis, including machine learning and data mining - Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks - Includes applications and case studies across all areas of AI in healthcare data

Biomedical Natural Language Processing

Author : Kevin Bretonnel Cohen
Publisher : John Benjamins Publishing Company
ISBN 13 : 9027271062
Total Pages : 174 pages
Book Rating : 4.0/5 (272 download)

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Book Synopsis Biomedical Natural Language Processing by : Kevin Bretonnel Cohen

Download or read book Biomedical Natural Language Processing written by Kevin Bretonnel Cohen and published by John Benjamins Publishing Company. This book was released on 2014-02-15 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Natural Language Processing is a comprehensive tour through the classic and current work in the field. It discusses all subjects from both a rule-based and a machine learning approach, and also describes each subject from the perspective of both biological science and clinical medicine. The intended audience is readers who already have a background in natural language processing, but a clear introduction makes it accessible to readers from the fields of bioinformatics and computational biology, as well. The book is suitable as a reference, as well as a text for advanced courses in biomedical natural language processing and text mining.

Biomedical Data Mining for Information Retrieval

Author : Sujata Dash
Publisher : John Wiley & Sons
ISBN 13 : 111971124X
Total Pages : 450 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Biomedical Data Mining for Information Retrieval by : Sujata Dash

Download or read book Biomedical Data Mining for Information Retrieval written by Sujata Dash and published by John Wiley & Sons. This book was released on 2021-08-24 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: BIOMEDICAL DATA MINING FOR INFORMATION RETRIEVAL This book not only emphasizes traditional computational techniques, but discusses data mining, biomedical image processing, information retrieval with broad coverage of basic scientific applications. Biomedical Data Mining for Information Retrieval comprehensively covers the topic of mining biomedical text, images and visual features towards information retrieval. Biomedical and health informatics is an emerging field of research at the intersection of information science, computer science, and healthcare and brings tremendous opportunities and challenges due to easily available and abundant biomedical data for further analysis. The aim of healthcare informatics is to ensure the high-quality, efficient healthcare, better treatment and quality of life by analyzing biomedical and healthcare data including patient’s data, electronic health records (EHRs) and lifestyle. Previously, it was a common requirement to have a domain expert to develop a model for biomedical or healthcare; however, recent advancements in representation learning algorithms allows us to automatically to develop the model. Biomedical image mining, a novel research area, due to the vast amount of available biomedical images, increasingly generates and stores digitally. These images are mainly in the form of computed tomography (CT), X-ray, nuclear medicine imaging (PET, SPECT), magnetic resonance imaging (MRI) and ultrasound. Patients’ biomedical images can be digitized using data mining techniques and may help in answering several important and critical questions relating to healthcare. Image mining in medicine can help to uncover new relationships between data and reveal new useful information that can be helpful for doctors in treating their patients. Audience Researchers in various fields including computer science, medical informatics, healthcare IOT, artificial intelligence, machine learning, image processing, clinical big data analytics.

Data Science Advancements in Pandemic and Outbreak Management

Author : Asimakopoulou, Eleana
Publisher : IGI Global
ISBN 13 : 1799867382
Total Pages : 255 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Data Science Advancements in Pandemic and Outbreak Management by : Asimakopoulou, Eleana

Download or read book Data Science Advancements in Pandemic and Outbreak Management written by Asimakopoulou, Eleana and published by IGI Global. This book was released on 2021-04-09 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pandemics are disruptive. Thus, there is a need to prepare and plan actions in advance for identifying, assessing, and responding to such events to manage uncertainty and support sustainable livelihood and wellbeing. A detailed assessment of a continuously evolving situation needs to take place, and several aspects must be brought together and examined before the declaration of a pandemic even happens. Various health organizations; crisis management bodies; and authorities at local, national, and international levels are involved in the management of pandemics. There is no better time to revisit current approaches to cope with these new and unforeseen threats. As countries must strike a fine balance between protecting health, minimizing economic and social disruption, and respecting human rights, there has been an emerging interest in lessons learned and specifically in revisiting past and current pandemic approaches. Such approaches involve strategies and practices from several disciplines and fields including healthcare, management, IT, mathematical modeling, and data science. Using data science to advance in-situ practices and prompt future directions could help alleviate or even prevent human, financial, and environmental compromise, and loss and social interruption via state-of-the-art technologies and frameworks. Data Science Advancements in Pandemic and Outbreak Management demonstrates how strategies and state-of-the-art IT have and/or could be applied to serve as the vehicle to advance pandemic and outbreak management. The chapters will introduce both technical and non-technical details of management strategies and advanced IT, data science, and mathematical modelling and demonstrate their applications and their potential utilization within the identification and management of pandemics and outbreaks. It also prompts revisiting and critically reviewing past and current approaches, identifying good and bad practices, and further developing the area for future adaptation. This book is ideal for data scientists, data analysts, infectious disease experts, researchers studying pandemics and outbreaks, IT, crisis and disaster management, academics, practitioners, government officials, and students interested in applicable theories and practices in data science to mitigate, prepare for, respond to, and recover from future pandemics and outbreaks.

Data Science for Healthcare

Author : Sergio Consoli
Publisher : Springer
ISBN 13 : 3030052494
Total Pages : 367 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Data Science for Healthcare by : Sergio Consoli

Download or read book Data Science for Healthcare written by Sergio Consoli and published by Springer. This book was released on 2019-02-23 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book seeks to promote the exploitation of data science in healthcare systems. The focus is on advancing the automated analytical methods used to extract new knowledge from data for healthcare applications. To do so, the book draws on several interrelated disciplines, including machine learning, big data analytics, statistics, pattern recognition, computer vision, and Semantic Web technologies, and focuses on their direct application to healthcare. Building on three tutorial-like chapters on data science in healthcare, the following eleven chapters highlight success stories on the application of data science in healthcare, where data science and artificial intelligence technologies have proven to be very promising. This book is primarily intended for data scientists involved in the healthcare or medical sector. By reading this book, they will gain essential insights into the modern data science technologies needed to advance innovation for both healthcare businesses and patients. A basic grasp of data science is recommended in order to fully benefit from this book.

Analysis of Images, Social Networks and Texts

Author : Wil M. P. van der Aalst
Publisher : Springer Nature
ISBN 13 : 3030395758
Total Pages : 366 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Analysis of Images, Social Networks and Texts by : Wil M. P. van der Aalst

Download or read book Analysis of Images, Social Networks and Texts written by Wil M. P. van der Aalst and published by Springer Nature. This book was released on 2020-02-01 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 8th International Conference on Analysis of Images, Social Networks and Texts, AIST 2019, held in Kazan, Russia, in July 2019. The 24 full papers and 10 short papers were carefully reviewed and selected from 134 submissions (of which 21 papers were rejected without being reviewed). The papers are organized in topical sections on general topics of data analysis; natural language processing; social network analysis; analysis of images and video; optimization problems on graphs and network structures; analysis of dynamic behaviour through event data.

Practical Natural Language Processing

Author : Sowmya Vajjala
Publisher : O'Reilly Media
ISBN 13 : 149205402X
Total Pages : 455 pages
Book Rating : 4.4/5 (92 download)

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Book Synopsis Practical Natural Language Processing by : Sowmya Vajjala

Download or read book Practical Natural Language Processing written by Sowmya Vajjala and published by O'Reilly Media. This book was released on 2020-06-17 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many books and courses tackle natural language processing (NLP) problems with toy use cases and well-defined datasets. But if you want to build, iterate, and scale NLP systems in a business setting and tailor them for particular industry verticals, this is your guide. Software engineers and data scientists will learn how to navigate the maze of options available at each step of the journey. Through the course of the book, authors Sowmya Vajjala, Bodhisattwa Majumder, Anuj Gupta, and Harshit Surana will guide you through the process of building real-world NLP solutions embedded in larger product setups. You’ll learn how to adapt your solutions for different industry verticals such as healthcare, social media, and retail. With this book, you’ll: Understand the wide spectrum of problem statements, tasks, and solution approaches within NLP Implement and evaluate different NLP applications using machine learning and deep learning methods Fine-tune your NLP solution based on your business problem and industry vertical Evaluate various algorithms and approaches for NLP product tasks, datasets, and stages Produce software solutions following best practices around release, deployment, and DevOps for NLP systems Understand best practices, opportunities, and the roadmap for NLP from a business and product leader’s perspective

Semantic Web for Effective Healthcare Systems

Author : Vishal Jain
Publisher : John Wiley & Sons
ISBN 13 : 1119764157
Total Pages : 352 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Semantic Web for Effective Healthcare Systems by : Vishal Jain

Download or read book Semantic Web for Effective Healthcare Systems written by Vishal Jain and published by John Wiley & Sons. This book was released on 2021-11-12 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: SEMANTIC WEB FOR EFFECTIVE HEALTHCARE SYSTEMS The book summarizes the trends and current research advances in web semantics, delineating the existing tools, techniques, methodologies, and research solutions Semantic Web technologies have the opportunity to transform the way healthcare providers utilize technology to gain insights and knowledge from their data and make treatment decisions. Both Big Data and Semantic Web technologies can complement each other to address the challenges and add intelligence to healthcare management systems. The aim of this book is to analyze the current status on how the semantic web is used to solve health data integration and interoperability problems, and how it provides advanced data linking capabilities that can improve search and retrieval of medical data. Chapters analyze the tools and approaches to semantic health data analysis and knowledge discovery. The book discusses the role of semantic technologies in extracting and transforming healthcare data before storing it in repositories. It also discusses different approaches for integrating heterogeneous healthcare data. This innovative book offers: The first of its kind and highlights only the ontology driven information retrieval mechanisms and techniques being applied to healthcare as well as clinical information systems; Presents a comprehensive examination of the emerging research in areas of the semantic web; Discusses studies on new research areas including ontological engineering, semantic annotation and semantic sentiment analysis; Helps readers understand key concepts in semantic web applications for the biomedical engineering and healthcare fields; Includes coverage of key application areas of the semantic web. Audience: Researchers and graduate students in computer science, biomedical engineering, electronic and software engineering, as well as industry scientific researchers, clinicians, and systems managers in biomedical fields.

Mining Text Data

Author : Charu C. Aggarwal
Publisher : Springer Science & Business Media
ISBN 13 : 1461432235
Total Pages : 527 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Mining Text Data by : Charu C. Aggarwal

Download or read book Mining Text Data written by Charu C. Aggarwal and published by Springer Science & Business Media. This book was released on 2012-02-03 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Text mining applications have experienced tremendous advances because of web 2.0 and social networking applications. Recent advances in hardware and software technology have lead to a number of unique scenarios where text mining algorithms are learned. Mining Text Data introduces an important niche in the text analytics field, and is an edited volume contributed by leading international researchers and practitioners focused on social networks & data mining. This book contains a wide swath in topics across social networks & data mining. Each chapter contains a comprehensive survey including the key research content on the topic, and the future directions of research in the field. There is a special focus on Text Embedded with Heterogeneous and Multimedia Data which makes the mining process much more challenging. A number of methods have been designed such as transfer learning and cross-lingual mining for such cases. Mining Text Data simplifies the content, so that advanced-level students, practitioners and researchers in computer science can benefit from this book. Academic and corporate libraries, as well as ACM, IEEE, and Management Science focused on information security, electronic commerce, databases, data mining, machine learning, and statistics are the primary buyers for this reference book.

Cochrane Handbook for Systematic Reviews of Interventions

Author : Julian P. T. Higgins
Publisher : Wiley
ISBN 13 : 9780470699515
Total Pages : 672 pages
Book Rating : 4.6/5 (995 download)

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Book Synopsis Cochrane Handbook for Systematic Reviews of Interventions by : Julian P. T. Higgins

Download or read book Cochrane Handbook for Systematic Reviews of Interventions written by Julian P. T. Higgins and published by Wiley. This book was released on 2008-11-24 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.

Sensor Data Analysis and Management

Author : A. Suresh
Publisher : John Wiley & Sons
ISBN 13 : 1119682428
Total Pages : 228 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Sensor Data Analysis and Management by : A. Suresh

Download or read book Sensor Data Analysis and Management written by A. Suresh and published by John Wiley & Sons. This book was released on 2021-11-22 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover detailed insights into the methods, algorithms, and techniques for deep learning in sensor data analysis Sensor Data Analysis and Management: The Role of Deep Learning delivers an insightful and practical overview of the applications of deep learning techniques to the analysis of sensor data. The book collects cutting-edge resources into a single collection designed to enlighten the reader on topics as varied as recent techniques for fault detection and classification in sensor data, the application of deep learning to Internet of Things sensors, and a case study on high-performance computer gathering and processing of sensor data. The editors have curated a distinguished group of perceptive and concise papers that show the potential of deep learning as a powerful tool for solving complex modelling problems across a broad range of industries, including predictive maintenance, health monitoring, financial portfolio forecasting, and driver assistance. The book contains real-time examples of analyzing sensor data using deep learning algorithms and a step-by-step approach for installing and training deep learning using the Python keras library. Readers will also benefit from the inclusion of: A thorough introduction to the Internet of Things for human activity recognition, based on wearable sensor data An exploration of the benefits of neural networks in real-time environmental sensor data analysis Practical discussions of supervised learning data representation, neural networks for predicting physical activity based on smartphone sensor data, and deep-learning analysis of location sensor data for human activity recognition An analysis of boosting with XGBoost for sensor data analysis Perfect for industry practitioners and academics involved in deep learning and the analysis of sensor data, Sensor Data Analysis and Management: The Role of Deep Learning will also earn a place in the libraries of undergraduate and graduate students in data science and computer science programs.

Finding What Works in Health Care

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309164257
Total Pages : 267 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Finding What Works in Health Care by : Institute of Medicine

Download or read book Finding What Works in Health Care written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-20 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.