Medical Imaging In Clinical Trials

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Medical Imaging in Clinical Trials

Author : Colin G. Miller
Publisher : Springer Science & Business Media
ISBN 13 : 1848827105
Total Pages : 420 pages
Book Rating : 4.8/5 (488 download)

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Book Synopsis Medical Imaging in Clinical Trials by : Colin G. Miller

Download or read book Medical Imaging in Clinical Trials written by Colin G. Miller and published by Springer Science & Business Media. This book was released on 2014-01-30 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last few years the use of medical imaging has increased exponentially in routine clinical practice. This has been reflected in a rapidly increasing use of medical imaging in clinical trials, through all phases. More recently this has culminated in a number of inter-disciplinary meetings with the various stake holders, including the FDA. Changes in the regulatory process has resulted, when it comes to the submission of data to the FDA, in a therapeutic agent where one or more of the trial end-points is the assessment of a radiological end-point. No longer is it sufficient to have the images read by the local investigator site. The FDA has also identified Medical Imaging as one of the key 6 points in the Critical Path initiative which was launched in 2004. This puts a keen focus on the role of imaging and the need to clearly identify and understand this aspect of clinical trials. As the pharmaceutical, biotech and medical device industry continues to identify ways to improve and speed up product development, medical imaging plays a more significant role. An understanding of the methodology and the metrics is therefore required but difficult to ascertain in one easy to read volume for individuals entering this field. This book will therefore fulfill this void, be it for the pharmaceutical personnel from medical director to monitor, or the Principal Investigator who is having to understand the complexities of the imaging and why it is having to be sent off-site for a 'central read.'

Handbook for Clinical Trials of Imaging and Image-Guided Interventions

Author : Nancy A. Obuchowski
Publisher : John Wiley & Sons
ISBN 13 : 1118849752
Total Pages : 223 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Handbook for Clinical Trials of Imaging and Image-Guided Interventions by : Nancy A. Obuchowski

Download or read book Handbook for Clinical Trials of Imaging and Image-Guided Interventions written by Nancy A. Obuchowski and published by John Wiley & Sons. This book was released on 2016-02-15 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook for Clinical Trials of Imaging and Image-Guided Interventions is the first single-source, multi-disciplinary reference, based on the didactic sessions presented at the annual ‘Clinical Trials Methodology Workshop’ for radiologists, radiation oncologists and imaging scientists (sponsored by the Radiological Society of North America (RSNA)). It focuses on educating radiologists, radiation oncologists and those involved in imaging research with how to design and conduct clinical trials to evaluate imaging technology and imaging biomarkers. The internationally renowned contributors take a broad approach, starting with principles of technology assessment, and then move into specific topics covering the clinical trials of therapy and clinical research in imaging guided interventions including radiotherapy. They discuss the use of imaging as a predictor of therapeutic response, screening trial design, and the practicalities of how to run an efficient clinical trial and good working practices. Later chapters provide a comprehensive array of quantitative methods including: an introduction to statistical considerations in study design, biostatistical analysis methods and their role in clinical imaging research, methods for quantitative imaging biomarker studies, and an introduction to cost effectiveness analysis. Handbook for Clinical Trials of Imaging and Image-Guided Interventions will educate and prepare radiologists at all levels and in all capacities in planning and conducting clinical imaging trials.

Advances in Computerized Analysis in Clinical and Medical Imaging

Author : J Dinesh Peter
Publisher : CRC Press
ISBN 13 : 0429820488
Total Pages : 292 pages
Book Rating : 4.4/5 (298 download)

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Book Synopsis Advances in Computerized Analysis in Clinical and Medical Imaging by : J Dinesh Peter

Download or read book Advances in Computerized Analysis in Clinical and Medical Imaging written by J Dinesh Peter and published by CRC Press. This book was released on 2019-10-28 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Computerized Analysis in Clinical and Medical Imaging book is devoted for spreading of knowledge through the publication of scholarly research, primarily in the fields of clinical & medical imaging. The types of chapters consented include those that cover the development and implementation of algorithms and strategies based on the use of geometrical, statistical, physical, functional to solve the following types of problems, using medical image datasets: visualization, feature extraction, segmentation, image-guided surgery, representation of pictorial data, statistical shape analysis, computational physiology and telemedicine with medical images. This book highlights annotations for all the medical and clinical imaging researchers’ a fundamental advances of clinical and medical image analysis techniques. This book will be a good source for all the medical imaging and clinical research professionals, outstanding scientists, and educators from all around the world for network of knowledge sharing. This book will comprise high quality disseminations of new ideas, technology focus, research results and discussions on the evolution of Clinical and Medical image analysis techniques for the benefit of both scientific and industrial developments. Features: Research aspects in clinical and medical image processing Human Computer Interaction and interface in imaging diagnostics Intelligent Imaging Systems for effective analysis using machine learning algorithms Clinical and Scientific Evaluation of Imaging Studies Computer-aided disease detection and diagnosis Clinical evaluations of new technologies Mobility and assistive devices for challenged and elderly people This book serves as a reference book for researchers and doctoral students in the clinical and medical imaging domain including radiologists. Industries that manufacture imaging modality systems and develop optical systems would be especially interested in the challenges and solutions provided in the book. Professionals and practitioners in the medical and clinical imaging may be benefited directly from authors’ experiences.

Brain Tumor Imaging

Author : Elke Hattingen
Publisher : Springer
ISBN 13 : 3642450407
Total Pages : 161 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Brain Tumor Imaging by : Elke Hattingen

Download or read book Brain Tumor Imaging written by Elke Hattingen and published by Springer. This book was released on 2015-09-02 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.

Medical Imaging for Health Professionals

Author : Raymond M. Reilly
Publisher : John Wiley & Sons
ISBN 13 : 1119120292
Total Pages : 528 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Medical Imaging for Health Professionals by : Raymond M. Reilly

Download or read book Medical Imaging for Health Professionals written by Raymond M. Reilly and published by John Wiley & Sons. This book was released on 2019-01-22 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the most common imaging technologies and their diagnostic applications so that pharmacists and other health professionals, as well as imaging researchers, can understand and interpret medical imaging science This book guides pharmacists and other health professionals and researchers to understand and interpret medical imaging. Divided into two sections, it covers both fundamental principles and clinical applications. It describes the most common imaging technologies and their use to diagnose diseases. In addition, the authors introduce the emerging role of molecular imaging including PET in the diagnosis of cancer and to assess the effectiveness of cancer treatments. The book features many illustrations and discusses many patient case examples. Medical Imaging for Health Professionals: Technologies and Clinical Applications offers in-depth chapters explaining the basic principles of: X-Ray, CT, and Mammography Technology; Nuclear Medicine Imaging Technology; Radionuclide Production and Radiopharmaceuticals; Magnetic Resonance Imaging (MRI) Technology; and Ultrasound Imaging Technology. It also provides chapters written by expert radiologists in well-explained terminology discussing clinical applications including: Cardiac Imaging; Lung Imaging; Breast Imaging; Endocrine Gland Imaging; Abdominal Imaging; Genitourinary Tract Imaging; Imaging of the Head, Neck, Spine and Brain; Musculoskeletal Imaging; and Molecular Imaging with Positron Emission Tomography (PET). Teaches pharmacists, health professionals, and researchers the basics of medical imaging technology Introduces all of the customary imaging tools—X-ray, CT, ultrasound, MRI, SPECT, and PET—and describes their diagnostic applications Explains how molecular imaging aids in cancer diagnosis and in assessing the effectiveness of cancer treatments Includes many case examples of imaging applications for diagnosing common diseases Medical Imaging for Health Professionals: Technologies and Clinical Applications is an important resource for pharmacists, nurses, physiotherapists, respiratory therapists, occupational therapists, radiological or nuclear medicine technologists, health physicists, radiotherapists, as well as researchers in the imaging field.

Advancing Nuclear Medicine Through Innovation

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309134153
Total Pages : 173 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council

Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Artificial Intelligence in Medical Imaging

Author : Erik R. Ranschaert
Publisher : Springer
ISBN 13 : 3319948784
Total Pages : 373 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Artificial Intelligence in Medical Imaging by : Erik R. Ranschaert

Download or read book Artificial Intelligence in Medical Imaging written by Erik R. Ranschaert and published by Springer. This book was released on 2019-01-29 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a thorough overview of the ongoing evolution in the application of artificial intelligence (AI) within healthcare and radiology, enabling readers to gain a deeper insight into the technological background of AI and the impacts of new and emerging technologies on medical imaging. After an introduction on game changers in radiology, such as deep learning technology, the technological evolution of AI in computing science and medical image computing is described, with explanation of basic principles and the types and subtypes of AI. Subsequent sections address the use of imaging biomarkers, the development and validation of AI applications, and various aspects and issues relating to the growing role of big data in radiology. Diverse real-life clinical applications of AI are then outlined for different body parts, demonstrating their ability to add value to daily radiology practices. The concluding section focuses on the impact of AI on radiology and the implications for radiologists, for example with respect to training. Written by radiologists and IT professionals, the book will be of high value for radiologists, medical/clinical physicists, IT specialists, and imaging informatics professionals.

Medical Imaging Informatics

Author : Alex A.T. Bui
Publisher : Springer Science & Business Media
ISBN 13 : 1441903852
Total Pages : 454 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Medical Imaging Informatics by : Alex A.T. Bui

Download or read book Medical Imaging Informatics written by Alex A.T. Bui and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Imaging Informatics provides an overview of this growing discipline, which stems from an intersection of biomedical informatics, medical imaging, computer science and medicine. Supporting two complementary views, this volume explores the fundamental technologies and algorithms that comprise this field, as well as the application of medical imaging informatics to subsequently improve healthcare research. Clearly written in a four part structure, this introduction follows natural healthcare processes, illustrating the roles of data collection and standardization, context extraction and modeling, and medical decision making tools and applications. Medical Imaging Informatics identifies core concepts within the field, explores research challenges that drive development, and includes current state-of-the-art methods and strategies.

Imaging in Drug Discovery and Early Clinical Trials

Author : Markus Rudin
Publisher : Springer Science & Business Media
ISBN 13 : 9783764377809
Total Pages : 408 pages
Book Rating : 4.3/5 (778 download)

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Book Synopsis Imaging in Drug Discovery and Early Clinical Trials by : Markus Rudin

Download or read book Imaging in Drug Discovery and Early Clinical Trials written by Markus Rudin and published by Springer Science & Business Media. This book was released on 2006-07-11 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph examines the contribution of imaging modalities to the stages of drug discovery and development, from early target validation to their use in clinical development programs. Chapters are devoted to the description of the drug discovery process, to the various imaging modalities preclinically and clinically, to applications of imaging during the optimization of a lead compound, addressing issues such as bioavailability and efficacy, and during drug safety evaluation.

Neuroscience Trials of the Future

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309442583
Total Pages : 111 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Neuroscience Trials of the Future by : National Academies of Sciences, Engineering, and Medicine

Download or read book Neuroscience Trials of the Future written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-07 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical trials for nervous system disorders. Participants in the workshop represented a range of diverse perspectives, including individuals not normally associated with traditional clinical trials. The purpose of this workshop was to generate discussion about not only what is feasible now, but what may be possible with the implementation of cutting-edge technologies in the future.

Imaging in Clinical Oncology

Author : Athanasios D. Gouliamos
Publisher : Springer Science & Business Media
ISBN 13 : 8847053854
Total Pages : 609 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Imaging in Clinical Oncology by : Athanasios D. Gouliamos

Download or read book Imaging in Clinical Oncology written by Athanasios D. Gouliamos and published by Springer Science & Business Media. This book was released on 2013-11-26 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This encompassing book is designed to contribute to a teamwork approach by promoting understanding between radiologists and clinical oncologists. All of the currently available imaging modalities of relevance in clinical oncology are covered, and the presentation of a broad spectrum of oncologic diseases (of most organ systems) on these modalities is discussed and illustrated. The role of multiparametric and multimodality imaging approaches providing both morphologic and functional information is considered in detail, and careful attention is paid to the latest developments in higher field (3T) MR imaging and advanced MR techniques such as diffusion-weighted imaging, diffusion tensor imaging, perfusion-weighted imaging and spectroscopy. The major challenge of incorporating progress in quantitative imaging technology into radiotherapy treatment planning, guidance, and monitoring is also addressed. This book will assist in refining the treatment approach in various oncologic diseases and organ systems based on specific imaging features. It will be of value to radiologists, oncologists, and other medical professionals involved in the diagnosis and treatment of oncology patients.

Understanding Clinical Research

Author : Renato D. Lopes
Publisher : McGraw Hill Professional
ISBN 13 : 0071792651
Total Pages : 272 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Understanding Clinical Research by : Renato D. Lopes

Download or read book Understanding Clinical Research written by Renato D. Lopes and published by McGraw Hill Professional. This book was released on 2013-05-22 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete guide to understanding and applying clinical research results Ideal for both researchers and healthcare providers Understanding Clinical Research addresses both the operational challenges of clinical trials and the needs of clinicians to comprehend the nuances of research methods to accurately analyze study results. This timely resource covers all aspects of clinical trials--from study design and statistics to regulatory oversight--and it delivers a detailed yet streamlined overview of must-know research topics. The text features an accessible three-part organization that traces the evolution of clinical research and explains the bedrock principles and unique challenges of clinical experimentation and observational research. Reinforcing this content are real-life case examples--drawn from the authors' broad experience--that put chapter concepts into action and contribute to a working knowledge of integral research techniques. FEATURES: The most definitive guide to promoting excellence in clinical research, designed to empower healthcare providers to assess a study's strengths and weaknesses with confidence and apply this knowledge to optimize patient outcomes In-depth coverage of fundamental research methods and protocols from preeminent authorities provides readers with an instructive primer and a springboard for ongoing clinical research education Clear, comprehensive three-part organization: Section One: Evolution of Clinical Research offers a succinct history of clinical trials, drug regulations, and the role of the FDA while covering the impact of information technology and academic research organizations Section Two: Principles of Clinical Experimentation takes you through the typical phases of clinical trials in the development of medical products, from initial human subject research to postapproval surveillance studies Section Three: Observational Research highlights the underlying principles, pitfalls, and methods for case-control studies, cohort studies, registries, and subgroup analyses within randomized trials

Musculoskeletal MRI E-Book

Author : Nancy M. Major
Publisher : Elsevier Health Sciences
ISBN 13 : 0323653561
Total Pages : 480 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Musculoskeletal MRI E-Book by : Nancy M. Major

Download or read book Musculoskeletal MRI E-Book written by Nancy M. Major and published by Elsevier Health Sciences. This book was released on 2019-10-04 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideal for residents, practicing radiologists, and fellows alike, this updated reference offers easy-to-understand guidance on how to approach musculoskeletal MRI and recognize abnormalities. Concise, to-the-point text covers MRI for the entire musculoskeletal system, presented in a highly templated format. Thoroughly revised and enhanced with full-color artwork throughout, this resource provides just the information you need to perform and interpret quality musculoskeletal MRI. Includes the latest protocols, practical advice, tips, and pearls for diagnosing conditions impacting the temporomandibular joint, shoulder, elbow, wrist/hand, spine, hips and pelvis, knee, and foot and ankle. Follows a quick-reference format throughout, beginning with basic technical information on how to obtain a quality examination, followed by a discussion of the normal appearance and the abnormal appearance for each small unit that composes a joint. Depicts both normal and abnormal anatomy, as well as disease progression, through more than 600 detailed, high-quality images, most of which are new to this edition. Features key information boxes throughout for a quick review of pertinent material.

Medical Imaging and Radiotherapy Research: Skills and Strategies

Author : Aarthi Ramlaul
Publisher : Springer Nature
ISBN 13 : 3030379442
Total Pages : 427 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Medical Imaging and Radiotherapy Research: Skills and Strategies by : Aarthi Ramlaul

Download or read book Medical Imaging and Radiotherapy Research: Skills and Strategies written by Aarthi Ramlaul and published by Springer Nature. This book was released on 2020-03-23 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This exciting new book equips radiography students and practitioners with the key skills and strategies required to undertake research within medical imaging and radiotherapy and to disseminate the research findings effectively. Quantitative and qualitative research methods are covered, with guidance provided on the entire research process, from literature researching, information management and literature evaluation through to data collection, data analysis, and writing up. Attention is drawn to sampling errors and other potential sources of bias, and the conduct of randomized controlled trials, systematic reviews, and meta-analyses are clearly explained. Specific instruction is given on the structure and presentation of dissertations, writing journal articles for publication, and the dissemination of research findings at conferences. Information on patient and public involvement in research and research funding bodies are also provided with advice on how to maximize the likelihood of success when submitting applications for funding.

Research Methods in Radiology

Author : Andrea S. Doria
Publisher : Thieme
ISBN 13 : 1604068272
Total Pages : 555 pages
Book Rating : 4.6/5 (4 download)

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Book Synopsis Research Methods in Radiology by : Andrea S. Doria

Download or read book Research Methods in Radiology written by Andrea S. Doria and published by Thieme. This book was released on 2018-02-09 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Methods in Radiology provides concise, practical insights on how to design clinical and experimental studies in diagnostic imaging. This unique resource encompasses contributions from leaders in academic radiology as well as top epidemiologists, biostatisticians, and librarians with vast multidisciplinary and radiology research experience. The material reflects years of expertise teaching core biostatistics in radiology principles to residents, fellows, radiologists, and epidemiologists. Given the vast amount of published information on research methodology and statistics in radiology, the authors' goal was to write a high-yield review and study tool rather than a comprehensive book. Key topics are succinctly addressed in each chapter, including measurements in radiology; decision analysis in radiology; and systemic reviews, evidence-based imaging, and knowledge translation. Online exercises related to each topic enable residents to prepare for radiology board examinations and research radiologists to apply knowledge to clinical studies. Key Highlights Introductory chapters on analysis of diagnostic tests, linear and logistic regression, meta-analysis, statistical inference, and economic evaluation provide easy-to-follow tutorials Each chapter includes learning objectives, basic concepts, supplementary tables, and ancillary online material Case studies with images, graphs, and tables highlight primary "take home" points Sample size calculations are illustrated for a wide range of research questions Code is included for use in R, free open-source software for statistical analysis This book is an indispensable review of research methodology for radiology students and residents. Practicing clinicians will also benefit from this precisely focused reference tool on clinical and experimental research.

Medical Imaging: Clinical Applications

Author : Kenneth Washington
Publisher :
ISBN 13 : 9781632426246
Total Pages : 277 pages
Book Rating : 4.4/5 (262 download)

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Book Synopsis Medical Imaging: Clinical Applications by : Kenneth Washington

Download or read book Medical Imaging: Clinical Applications written by Kenneth Washington and published by . This book was released on 2019-06-03 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: The visual representation of the interior of the human body for the purpose of clinical analysis and for the diagnosis and treatment of diseases is achieved through medical imaging. It also allows the understanding of normal physiology and anatomy. Some medical imaging techniques are magnetic resonance imaging (MRI), endoscopy, positron emission tomography (PET), medical ultrasonography, etc. Volume rendering techniques are used to provide a 3D visualization of the body or region of the body under study. Imaging techniques such as MRI and PET are typically used in neuroscience and oncology. Medical imaging may be used also to gain insight into complications in pregnancy, routine prenatal care and intercurrent diseases. Medical imaging is also a major tool in clinical trials as it allows quick visualization and assessment. The topics covered in this extensive book deal with the clinical applications of medical imaging. It aims to present researches that have transformed this discipline and aided its advancement. This book is a vital tool for all researching or studying this discipline as it gives incredible insights into emerging trends and concepts.

50 Imaging Studies Every Doctor Should Know

Author : Christoph Lee
Publisher : Oxford University Press
ISBN 13 : 0190223707
Total Pages : 353 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis 50 Imaging Studies Every Doctor Should Know by : Christoph Lee

Download or read book 50 Imaging Studies Every Doctor Should Know written by Christoph Lee and published by Oxford University Press. This book was released on 2016-08-24 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: 50 Imaging Studies Every Doctors Should Know presents key studies that have shaped the practice of radiology. Selected using a rigorous methodology, the studies cover topics including: headache, back pain, chest pain, abdominal and pelvic pain, bone, joint, and extremity pain, cancer screening and management, and radiation exposure from medical imaging. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case and radiologic image conclude each review, followed by brief information on other relevant studies. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice.