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Mechanobiology Of Fracture Healing
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Book Synopsis Multiscale Mechanobiology of Bone Remodeling and Adaptation by : Peter Pivonka
Download or read book Multiscale Mechanobiology of Bone Remodeling and Adaptation written by Peter Pivonka and published by Springer. This book was released on 2017-06-20 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.
Book Synopsis Mechanobiology in Health and Disease by : Stefaan Verbruggen
Download or read book Mechanobiology in Health and Disease written by Stefaan Verbruggen and published by Academic Press. This book was released on 2018-08-09 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. - Provides an essential digest of primary research from many fields and disciplines in one convenient volume - Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives - Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science
Book Synopsis Elements of Fracture Fixation - E-book by : Anand J. Thakur
Download or read book Elements of Fracture Fixation - E-book written by Anand J. Thakur and published by Elsevier Health Sciences. This book was released on 2015-07-29 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Timely, accurate, and up-to-date text clearly explaining the fundamentals of fracture healing and bone fixation in a format that is concise, well organized and easy to follow. It is extremely well illustrated and addresses the biomechanical principles and usage techniques of the wide range of modern orthopaedic trauma implants in use today.• An in-depth resource to the amply stocked tool-box of today's fracture surgeon• A compendium of fracture fixation written by an experienced surgeon for fellows, residents and masters• A detailed overview of biomechanics, biology, implants and materials relevant to fracture care• Elegantly illustrated and lucidly explained presentations of today's fracture fixation devices• The designs, the application techniques in various anatomical regions, mechanical effects, hazards and contraindications are described along elucidative graphics• Not so commonly found details of intramedullary nail and use of Poller screws in its insertion, hazards of use of traction table, methods to perfect insertion of intramedullary hip fixation device, minute details of cables, pins and wires, several configurations of external fixator, new concept of reverse dynamization, a brief exposure of spinal instrumentation and several techniques of minimal invasive osteosynthesis are a few of its features
Book Synopsis Mechanobiology of Fracture Healing by : Lutz E. Claes
Download or read book Mechanobiology of Fracture Healing written by Lutz E. Claes and published by Springer Nature. This book was released on 2022-04-24 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a summary of research on the biomechanics of fracture fixation and mechanobiology of fracture healing. The author, a known expert, provides an overview of the state of art, his own research together with that of his co-workers and collaborators; he describes the ideas and findings from the beginning of this research field in the 1960s up to the clinical consequences and applications of today. The book discusses the mechanobiology of fracture healing, illustrates the numerical methods that simulate fracture healing processes, and depicts specific research methods of experimental studies. Finally, it provides conclusions for the improvement of fracture treatment that will be of use in clinical applications nowadays. This book will be a valuable resource of knowledge for students and scientists in the field of bioengineering, experimental biology, and biomechanics, helping them to identify the correct conditions and analysis for their respective research and receive an understanding of the research field from its beginning until today. For experimental and clinical surgeons active in the field of fracture healing, this book will provide a useful historical overview over this translational research field.
Book Synopsis Musculoskeletal Disorders and the Workplace by : Institute of Medicine
Download or read book Musculoskeletal Disorders and the Workplace written by Institute of Medicine and published by National Academies Press. This book was released on 2001-05-24 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every year workers' low-back, hand, and arm problems lead to time away from jobs and reduce the nation's economic productivity. The connection of these problems to workplace activities-from carrying boxes to lifting patients to pounding computer keyboards-is the subject of major disagreements among workers, employers, advocacy groups, and researchers. Musculoskeletal Disorders and the Workplace examines the scientific basis for connecting musculoskeletal disorders with the workplace, considering people, job tasks, and work environments. A multidisciplinary panel draws conclusions about the likelihood of causal links and the effectiveness of various intervention strategies. The panel also offers recommendations for what actions can be considered on the basis of current information and for closing information gaps. This book presents the latest information on the prevalence, incidence, and costs of musculoskeletal disorders and identifies factors that influence injury reporting. It reviews the broad scope of evidence: epidemiological studies of physical and psychosocial variables, basic biology, biomechanics, and physical and behavioral responses to stress. Given the magnitude of the problem-approximately 1 million people miss some work each year-and the current trends in workplace practices, this volume will be a must for advocates for workplace health, policy makers, employers, employees, medical professionals, engineers, lawyers, and labor officials.
Download or read book Mechanobiology written by Glen L. Niebur and published by Elsevier. This book was released on 2019-12-01 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. - Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli - Provides a review of diseases with known or purported mechanobiological underpinnings - Includes the role of mechanobiology in tissue engineering and regenerative medicine - Covers experimental methods to capture mechanobiological phenomena
Book Synopsis Extracellular and Intracellular Signaling by : James D. Adams
Download or read book Extracellular and Intracellular Signaling written by James D. Adams and published by Royal Society of Chemistry. This book was released on 2011 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets.
Book Synopsis Basic Orthopaedic Biomechanics by : Van C Mow
Download or read book Basic Orthopaedic Biomechanics written by Van C Mow and published by Lippincott Raven. This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This classic text has been completely revised and updated to reflect the latest advances in orthopaedic biomechanics, and the successful application of mechanical laws to the locomotor system of the human body. The Second Edition features new chapters on cell-matrix interactions in articular cartilage and on the quantitative anatomy of diarthrodial joints, as well as expanded coverage of the biomechanics of artificial hip and knee joints.
Book Synopsis Regenerative Rehabilitation by : Sarah M. Greising
Download or read book Regenerative Rehabilitation written by Sarah M. Greising and published by Springer Nature. This book was released on 2022-06-01 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume presents the current state of research on regenerative rehabilitation across a broad range of neuro- and musculoskeletal tissues. At its core, the primary goal of regenerative rehabilitation is to restore function after damage to bones, skeletal muscles, cartilage, ligaments/tendons, or tissues of the central and peripheral nervous systems. The authors describe the physiology of these neuro- and musculoskeletal tissue types and their inherent plasticity. The latter quality is what enables these tissues to adapt to mechanical and/or chemical cues to improve functional capacity. As a result, readers will learn how regenerative rehabilitation exploits that quality, to trigger positive changes in tissue function. Combining basic, translational, and clinical aspects of the topic, the book offers a valuable resource for both scientists and clinicians in the regenerative rehabilitation field.
Book Synopsis Nonlinear Mechanics of Soft Fibrous Materials by : Luis Dorfmann
Download or read book Nonlinear Mechanics of Soft Fibrous Materials written by Luis Dorfmann and published by Springer. This book was released on 2014-12-02 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents a state-of-the-art overview of the fundamental theories, established models and ongoing research related to the modeling of these materials. Two approaches are conventionally used to develop constitutive relations for highly deformable fibrous materials. According to the phenomenological approach, a strain energy density function can be defined in terms of strain invariants. The other approach is based on kinetic theories, which treats a fibrous material as a randomly oriented inter-tangled network of long molecular chains bridged by permanent and temporary junctions. At the micro-level, these are associated with chemical crosslinks and active entanglements, respectively. The papers include carefully crafted overviews of the fundamental formulation of the three-dimensional theory from several points of view, and address their equivalences and differences. Also included are solutions to boundary-value problems which are amenable to experimental verification. A further aspect is the elasticity of filaments, stability of equilibrium and thermodynamics of the molecular network theory.
Book Synopsis Articular Cartilage Dynamics by : David W. Smith
Download or read book Articular Cartilage Dynamics written by David W. Smith and published by Springer. This book was released on 2018-11-19 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the anatomy and physiology of cartilage tissue in an integrated way. The emphasis is on how cartilage tissue functions and maintains homeostasis in a challenging mechanical environment. Supported by hundreds of references, the book posts new hypotheses explaining how cartilage adapts and achieves homeostasis in vivo, and tests them against available data. This exploratory approach creates a sense of discovery that the reader can join, or perhaps test themselves through their own research. The main benefit will be obtained by research students and professors looking to understand the deeper concepts that will further their own research, or clinicians (including health professionals and surgeons) who want to gain a deeper physiological understanding of cartilage tissue, which can then serve as a basis for more rational clinical decision-making they need to make on a daily basis. To help bridge the gap between basic science and clinically relevant joint disease, applications and interpretations of key physiological concepts are discussed in the context of osteoarthritis at the end of most chapters.
Book Synopsis Biological Mechanisms of Tooth Movement by : Vinod Krishnan
Download or read book Biological Mechanisms of Tooth Movement written by Vinod Krishnan and published by John Wiley & Sons. This book was released on 2021-05-24 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Mechanisms of Tooth Movement This new edition continues to be an authoritative reference to the scientific foundations underpinning clinical orthodontics The newly and thoroughly revised Third Edition of Biological Mechanisms of Tooth Movement delivers a comprehensive reference for orthodontic trainees and specialists. It is fully updated to include new chapters on personalized orthodontics as well as the inflammatory process occurring in the dental and paradental tissues. It is heavily illustrated throughout, making it easier for readers to understand and retain the information discussed within. The topics covered range from bone biology, the effects of mechanical loading on tissues and cells, genetics, tissue remodeling, and the effects of diet, drugs, and systemic diseases. The Third Edition of Biological Mechanisms of Tooth Movement features seven sections that cover subjects such as: The development of biological concepts in orthodontics, including the cellular and molecular biology behind orthodontic tooth movement Mechanics meets biology, including the effects of mechanical loading on hard and soft tissues and cells, and biological reactions to temporary anchorage devices Inflammation and orthodontics, including markers for tissue remodeling in the gingival crevicular fluid and saliva Personalized diagnosis and treatment based on genomic criteria, including the genetic influences on orthodontic tooth movement Rapid orthodontics, including methods to accelerate or decelerate orthodontic tooth movement Perfect for residents and PhD students of orthodontic and periodontal programs, Biological Mechanisms of Tooth Movement is also useful to academics, clinicians, bone biologists, and researchers with an interest in the mechanics and biology of tooth movement.
Book Synopsis Bone Tissue Engineering by : Jeffrey O. Hollinger
Download or read book Bone Tissue Engineering written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2004-10-14 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t
Book Synopsis Theoretical Biomechanics by : Vaclav Klika
Download or read book Theoretical Biomechanics written by Vaclav Klika and published by BoD – Books on Demand. This book was released on 2011-11-25 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: During last couple of years there has been an increasing recognition that problems arising in biology or related to medicine really need a multidisciplinary approach. For this reason some special branches of both applied theoretical physics and mathematics have recently emerged such as biomechanics, mechanobiology, mathematical biology, biothermodynamics. This first section of the book, General notes on biomechanics and mechanobiology, comprises from theoretical contributions to Biomechanics often providing hypothesis or rationale for a given phenomenon that experiment or clinical study cannot provide. It deals with mechanical properties of living cells and tissues, mechanobiology of fracture healing or evolution of locomotor trends in extinct terrestrial giants. The second section, Biomechanical modelling, is devoted to the rapidly growing field of biomechanical models and modelling approaches to improve our understanding about processes in human body. The last section called Locomotion and joint biomechanics is a collection of works on description and analysis of human locomotion, joint stability and acting forces.
Book Synopsis Joint Function Preservation by : Alberto Gobbi
Download or read book Joint Function Preservation written by Alberto Gobbi and published by Springer Nature. This book was released on 2021-11-03 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: This user-friendly, pragmatic book discusses the normal and pathological conditions of the appendicular skeleton, with a focus on the preservation of joint function, providing a detailed overview of strategies for both common and complex joint preservation. The first section covers basic topics, ranging from joints homeostasis and biomechanics, to genetics, bio-orthopedics, tissue engineering and 3D bioprinting. The following sections are each dedicated to a specific joint – its functional anatomy, pathologic conditions, diagnostics and treatment. This book is of interest to orthopedists and sports medicine specialists treating common and complex injuries of the joints.
Book Synopsis Structural Interfaces and Attachments in Biology by : Stavros Thomopoulos
Download or read book Structural Interfaces and Attachments in Biology written by Stavros Thomopoulos and published by Springer Science & Business Media. This book was released on 2012-10-05 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Attachment of dissimilar materials in engineering and surgical practice is a perennial challenge. Bimaterial attachment sites are common locations for injury, repeated injury, and mechanical failure. Nature presents several highly effective solutions to the challenge of bimaterial attachment that differ from those found in engineering practice. Structural Interfaces and Attachments in Biology describes the attachment of dissimilar materials from multiple perspectives. The text will simultaneously elucidate natural bimaterial attachments and outline engineering principles underlying successful attachments to the communities of tissue engineers and surgeons. Included an in-depth analysis of the biology of attachments in the body and mechanisms by which robust attachments are formed, a review of current concepts of attaching dissimilar materials in surgical practice and a discussion of bioengineering approaches that are currently being developed.
Book Synopsis Essential Biomechanics for Orthopedic Trauma by : Brett D. Crist
Download or read book Essential Biomechanics for Orthopedic Trauma written by Brett D. Crist and published by Springer Nature. This book was released on 2020-02-29 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomechanics is often overlooked when dealing with orthopedic injuries, whether regarding prevention or treatment, and practicing surgeons and surgeons-in-training may feel overwhelmed when referring to a book with a more complicated basic science approach. In order to make the subject clinically relevant to orthopedic trauma surgery, this unique text presents numerous clinical case examples to demonstrate clearly and effectively the principles biomechanics of injury, fixation and fracture healing. Divided into five sections, the opening chapters cover the essentials of stress and strain relevant to bone and joints and how this relates to fractures and their healing, complete with illustrative case material. This case-based approach is carried throughout the book, with part two discussing biomechanical principles of external fixation for diaphyseal and periarticular fractures, limb lengthening and deformity correction. Tension band wiring for both olecranon and patella fractures are covered in part three, and both locking and nonlocking plates are illustrated in part four. The final section describes biomechanical principles of intramedullary nails for a variety of fractures and nonunions, as well as arthrodesis and lengthening. Generous radiological images and intraoperative photos provide a helpful visual enhancement for the clinical material. Making the sometimes esoteric topic of biomechanics more clinically relevant to the practicing clinician, Essential Biomechanics for Orthopedic Trauma will be an excellent resource not only for orthopedic surgeons, sports medicine specialists and trauma surgeons, but also medical and biomedical engineering students and residents.
