Managing Myeloproliferative Neoplasms

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Managing Myeloproliferative Neoplasms

Author : Ruben A. Mesa
Publisher : Cambridge University Press
ISBN 13 : 1316033775
Total Pages : 207 pages
Book Rating : 4.3/5 (16 download)

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Book Synopsis Managing Myeloproliferative Neoplasms by : Ruben A. Mesa

Download or read book Managing Myeloproliferative Neoplasms written by Ruben A. Mesa and published by Cambridge University Press. This book was released on 2016-03-31 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise, practical, case-based book documenting examples and scenarios that will help you manage challenging clinical issues for patients with myeloproliferative neoplasms. The editors and authors have strived to distil the very latest information in this rapidly advancing field in a way that will help you to update your practice and manage your patients. The key focuses are: diagnosis, both standard and challenging; both day-to-day management as well as special situations such as surgery, thrombotic events and pregnancy; and finally, managing evolving situations with MPN such as progression to acute myeloid leukemia. This book is an outstanding resource that includes a discussion of both classical myeloproliferative neoplasms, such as essential thrombocythemia, polycythemia vera and myelofibrosis, and also less common disorders such as systemic mast cell disease, hypereosinophilia, MPN/MBS overlap syndromes and atypical CML, amongst others. This book is a practical reference for practitioners, hematologists, medical oncologists and trainees.

Myeloproliferative Neoplasms

Author : Tiziano Barbui
Publisher : Springer Science & Business Media
ISBN 13 : 3642249884
Total Pages : 235 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Myeloproliferative Neoplasms by : Tiziano Barbui

Download or read book Myeloproliferative Neoplasms written by Tiziano Barbui and published by Springer Science & Business Media. This book was released on 2012-02-03 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.

Fast Facts: Myeloproliferative Neoplasms

Author : R.A. Mesa
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1910797804
Total Pages : 117 pages
Book Rating : 4.9/5 (17 download)

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Book Synopsis Fast Facts: Myeloproliferative Neoplasms by : R.A. Mesa

Download or read book Fast Facts: Myeloproliferative Neoplasms written by R.A. Mesa and published by Karger Medical and Scientific Publishers. This book was released on 2019-02-11 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presentation of the myeloproliferative neoplasms (MPNs) varies widely, and correct diagnosis and management can be challenging, and is becoming more complex as understanding of the underlying molecular basis for these disorders emerges. Appropriate management is increasingly informed by accurate risk stratification founded on understanding of cytogenetic and molecular markers, as well as the clinical presentation. 'Fast Facts: myeloproliferative neoplasms' focuses on the three most common chronic MPNs: • Essential thrombocythemia (ET) – characterized by increased platelet count • Polycythemia vera (PV) – characterized by excessive production of red blood cells • Primary myelofibrosis – a more severe and heterogenous disorder that may overlap with ET and PV but is commonly associated with anemia. Written by two leading experts in the field, Fast Facts: myeloproliferative neoplasms provides concise, up-to-date and practical guidance on the accurate diagnosis, risk stratification and management of these MPNs. It also provides key insights into our growing understanding of the underlying molecular and genetic basis of these disorders, and how this is informing risk stratification and management strategies. This concise handbook will be invaluable to clinicians, medical students, nurses, pharmacists and scientists in understanding and overcoming the everyday and rarer challenges associated with MPN.

Chronic Myeloproliferative Disorders

Author : Tariq Mughal
Publisher : CRC Press
ISBN 13 : 9780415415989
Total Pages : 0 pages
Book Rating : 4.4/5 (159 download)

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Book Synopsis Chronic Myeloproliferative Disorders by : Tariq Mughal

Download or read book Chronic Myeloproliferative Disorders written by Tariq Mughal and published by CRC Press. This book was released on 2008-08-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the new classification of chronic myeloproliferative disorders, and the rise of interest in molecularly targeted therapies, this timely text brings together international experts on the topic to discuss the current technologies and their implications for the treatment of patients. This title comprehensively covers chronic myeloid leukemia and Ph-negative chronic myeloproliferative disorders and is an essential resource for all practitioners in Hematologic Oncology.

Myeloproliferative Neoplasms

Author : Srdan Verstovsek
Publisher : Springer Science & Business Media
ISBN 13 : 1607612666
Total Pages : 230 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Myeloproliferative Neoplasms by : Srdan Verstovsek

Download or read book Myeloproliferative Neoplasms written by Srdan Verstovsek and published by Springer Science & Business Media. This book was released on 2010-10-17 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments.

Biology and Treatment of Leukemia and Bone Marrow Neoplasms

Author : Vinod Pullarkat
Publisher : Springer Nature
ISBN 13 : 3030783111
Total Pages : 200 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Biology and Treatment of Leukemia and Bone Marrow Neoplasms by : Vinod Pullarkat

Download or read book Biology and Treatment of Leukemia and Bone Marrow Neoplasms written by Vinod Pullarkat and published by Springer Nature. This book was released on 2021-10-09 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students.

Fast Facts: Myeloproliferative Neoplasms

Author : Ruben A. Mesa
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1910797790
Total Pages : 117 pages
Book Rating : 4.9/5 (17 download)

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Book Synopsis Fast Facts: Myeloproliferative Neoplasms by : Ruben A. Mesa

Download or read book Fast Facts: Myeloproliferative Neoplasms written by Ruben A. Mesa and published by Karger Medical and Scientific Publishers. This book was released on 2019 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presentation of the myeloproliferative neoplasms (MPNs) varies widely, and correct diagnosis and management can be challenging, and is becoming more complex as understanding of the underlying molecular basis for these disorders emerges. Appropriate management is increasingly informed by accurate risk stratification founded on understanding of cytogenetic and molecular markers, as well as the clinical presentation. 'Fast Facts: myeloproliferative neoplasms' focuses on the three most common chronic MPNs: * Essential thrombocythemia (ET) - characterized by increased platelet count * Polycythemia vera (PV) - characterized by excessive production of red blood cells * Primary myelofibrosis - a more severe and heterogenous disorder that may overlap with ET and PV but is commonly associated with anemia. Written by two leading experts in the field, Fast Facts: myeloproliferative neoplasms provides concise, up-to-date and practical guidance on the accurate diagnosis, risk stratification and management of these MPNs. It also provides key insights into our growing understanding of the underlying molecular and genetic basis of these disorders, and how this is informing risk stratification and management strategies. This concise handbook will be invaluable to clinicians, medical students, nurses, pharmacists and scientists in understanding and overcoming the everyday and rarer challenges associated with MPN.

Oxford Specialist Handbook: Myeloproliferative Neoplasms

Author : Tariq I. Mughal
Publisher : Oxford University Press, USA
ISBN 13 : 0198744218
Total Pages : 361 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Oxford Specialist Handbook: Myeloproliferative Neoplasms by : Tariq I. Mughal

Download or read book Oxford Specialist Handbook: Myeloproliferative Neoplasms written by Tariq I. Mughal and published by Oxford University Press, USA. This book was released on 2020-08-06 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of myeloproliferative neoplasms (MPN) disorders has grown considerably over the past four decades. Myeloproliferative Neoplasms offers a detailed evidence-based guide to MPNs in an easily accessible format, structure to facilitate learning specialist information presenting core information in 'bite size' chunks.

Oxford Specialist Handbook: Myeloproliferative Neoplasms

Author : Tariq I. Mughal
Publisher : Oxford University Press
ISBN 13 : 0191061735
Total Pages : 432 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Oxford Specialist Handbook: Myeloproliferative Neoplasms by : Tariq I. Mughal

Download or read book Oxford Specialist Handbook: Myeloproliferative Neoplasms written by Tariq I. Mughal and published by Oxford University Press. This book was released on 2020-09-24 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of myeloproliferative neoplasms (MPN) disorders, a group of clonal haematological malignancies characterized by excessive accumulation of one or more myeloid cell lineages, has grown considerably over the past four decades. Myeloproliferative Neoplasms offers a detailed evidence-based guide to MPNs in an easily accessible format, structured to facilitate learning specialist information by presenting core information in 'bite size' chunks. Each chapter summarises the state-of-the art preclinical and clinical knowledge, and its impact on the clinical management of patients with MPNs. This practical guide, written by experts in the field, is essential reading for oncologists, haematologists, and other health care professionals interested in the field of MPNs.

Bone Marrow Biopsy Pathology

Author : Christine Beham-Schmid
Publisher : Springer Nature
ISBN 13 : 3662603098
Total Pages : 533 pages
Book Rating : 4.6/5 (626 download)

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Book Synopsis Bone Marrow Biopsy Pathology by : Christine Beham-Schmid

Download or read book Bone Marrow Biopsy Pathology written by Christine Beham-Schmid and published by Springer Nature. This book was released on 2020-08-05 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, superbly illustrated reference is designed to provide practical diagnostic assistance for hematopathologists when dealing with common and uncommon lesions in bone marrow trephine biopsies (BMTBs). At the heart of the book is a systematic analysis of neoplastic hematological and non-hematological disease entities, with concise identification of the key features of myeloproliferative neoplasms, myelodysplastic syndromes, acute and chronic leukemias, eosinophilia-associated myeloid/lymphoid neoplasms, lymphoproliferative disorders, and selected non-hematopoietic malignancies. Relevant examples of BMTBs are presented, with microscopic description, high-quality photomicrographs, and clinical data. The book also explains how to assess hematopoietic and stromal components of normal BMTBs, identifies the heterogeneous patterns that may be observed in healthy individuals, and analyzes reactive conditions, with particular attention to diagnostic problems and pitfalls.

Myeloproliferative Disorders

Author : Richard T. Silver
Publisher : CRC Press
ISBN 13 : 1000687309
Total Pages : 240 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Myeloproliferative Disorders by : Richard T. Silver

Download or read book Myeloproliferative Disorders written by Richard T. Silver and published by CRC Press. This book was released on 2007-10-11 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the recent discovery of JAK2 mutations in myeloproliferative disorders, medical science has taken a revolutionary stride forward toward understanding the pathogenesis of these diseases. This new advancement translates not only to a more rapid and reliable diagnosis, but also allows groundbreaking research into the development of new therapeuti

Living Well with a Myeloproliferative Neoplasm (MPN)

Author : Gowin Krisstina
Publisher : Spry Publishing
ISBN 13 : 1938170938
Total Pages : 157 pages
Book Rating : 4.9/5 (381 download)

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Book Synopsis Living Well with a Myeloproliferative Neoplasm (MPN) by : Gowin Krisstina

Download or read book Living Well with a Myeloproliferative Neoplasm (MPN) written by Gowin Krisstina and published by Spry Publishing. This book was released on 2019-02-14 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: The journey through a diagnosis of MPN is different for each person and there is no road map that will work for everyone. In her book, LIVING WELL with a Myeloproliferative Neoplasm, Dr. Krisstina Gowin provides an essential guide to treatment options and symptom management, while helping patients and their caregivers take an informed and active role in getting quality care, communicating with their healthcare team, and developing a support system. As importantly, she addresses all aspects of the patient—body, mind, psychosocial and spiritual health—promoting overall wellness in bodies already challenged by disease. By following Dr. Gowin’s integrative approach— combining traditional and complementary therapies—MPN patients can get started on a path to living the best life possible every day. -- Gowin

Contemporary Management of Myeloproliferative Neoplasms

Author : Brady L. Stein
Publisher :
ISBN 13 : 9789386056436
Total Pages : pages
Book Rating : 4.0/5 (564 download)

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Book Synopsis Contemporary Management of Myeloproliferative Neoplasms by : Brady L. Stein

Download or read book Contemporary Management of Myeloproliferative Neoplasms written by Brady L. Stein and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Care for the Whole Patient

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309134161
Total Pages : 454 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cancer Care for the Whole Patient by : Institute of Medicine

Download or read book Cancer Care for the Whole Patient written by Institute of Medicine and published by National Academies Press. This book was released on 2008-03-19 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer care today often provides state-of-the-science biomedical treatment, but fails to address the psychological and social (psychosocial) problems associated with the illness. This failure can compromise the effectiveness of health care and thereby adversely affect the health of cancer patients. Psychological and social problems created or exacerbated by cancer--including depression and other emotional problems; lack of information or skills needed to manage the illness; lack of transportation or other resources; and disruptions in work, school, and family life--cause additional suffering, weaken adherence to prescribed treatments, and threaten patients' return to health. Today, it is not possible to deliver high-quality cancer care without using existing approaches, tools, and resources to address patients' psychosocial health needs. All patients with cancer and their families should expect and receive cancer care that ensures the provision of appropriate psychosocial health services. Cancer Care for the Whole Patient recommends actions that oncology providers, health policy makers, educators, health insurers, health planners, researchers and research sponsors, and consumer advocates should undertake to ensure that this standard is met.

Myeloproliferative Disorders

Author : Anthony M. Camden
Publisher : Nova Science Publishers
ISBN 13 : 9781633212015
Total Pages : 0 pages
Book Rating : 4.2/5 (12 download)

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Book Synopsis Myeloproliferative Disorders by : Anthony M. Camden

Download or read book Myeloproliferative Disorders written by Anthony M. Camden and published by Nova Science Publishers. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myeloproliferative disorders are a group of clonal haematological neoplasms characterised by proliferation of one or more cells of myeloid lineage. They are the result of acquired mutations in the progenitor cell leading to hyper proliferation or neoplastic expansion of more mature forms of myeloid cells. Cells retain their functional ability with some degree of defects and also lead to suppression of normal stem cells. The most common type of Myeloproliferative Neoplasms (MPN) can broadly be classified into BCR ABL positive (Chronic Myelogenous Leukemia) and BCR ABL negative Disorders (Polycythemia Vera PV, Essential Thrombocytosis ET and Primary Myelofibrosis PMF). There are other rare types which have relatively low incidence like chronic neutrophilic leukemia, chronic eosinophilic leukemia, systemic mastocytosis and myeloproliferative neoplasms unclassifiable. These are the indolent type of haematological malignancies associated with marrow hypercellularity and organomegaly, with gradual progression to myelofibrosis or transformation to acute leukemias. During the dormant course of the BCR ABL negative MPN, they are more prone to thrombo-hemorrhagic complications and the treatment strategy is directed mostly to prevent complications. The past decade; therapies for BCR ABL positive disease (CML) have been a milestone achievement in keeping the disease in remission for many years, preventing major complications and halting the progression of the disease. This book discusses the classification, diagnosis and treatment of myeloproliferative diseases and provides insight on the symptoms and risk factors involved in the diseases.

The EBMT Handbook

Author : Nicolaus Kröger
Publisher :
ISBN 13 : 9781013273674
Total Pages : 688 pages
Book Rating : 4.2/5 (736 download)

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Book Synopsis The EBMT Handbook by : Nicolaus Kröger

Download or read book The EBMT Handbook written by Nicolaus Kröger and published by . This book was released on 2020-10-08 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America

Author : John Mascarenhas
Publisher : Elsevier Health Sciences
ISBN 13 : 0323795897
Total Pages : 240 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America by : John Mascarenhas

Download or read book Myeloproliferative Neoplasms, An Issue of Hematology/Oncology Clinics of North America written by John Mascarenhas and published by Elsevier Health Sciences. This book was released on 2021-02-27 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics, guest edited by Drs. Ronald Hoffman, Ross Levine, John Mascarenhas, and Raajit Rampal, is dedicated to Myeloproliferative Neoplasms. This issue is one of six selected each year by the series consulting editors, Drs. George P. Canellos and Edward J. Benz. Topics in this issue include—but are not limited to— Overview of pathophysiology and potential drug targets, The role of the megakaryocyte, Epigenetics, Genetics, Novel technologies for understanding MPN biology, Important pathology considerations, Current Clinical investigations, Quality of life, Application of stem cell therapy, Immunotherapy approaches, Clinical unmet needs in ET/PV, Accelerated and blast phase MPNs, Epidemiology, Thrombotic and hemorrhagic complications, Murine modeling, The microenvironment in MPNs, MDS/MPN overlap syndrome, and Advancing effective clinical trial designs.