An Introduction to Toxicology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 144715553X
Total Pages : 338 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis An Introduction to Toxicology by : Philip C. Burcham

Download or read book An Introduction to Toxicology written by Philip C. Burcham and published by Springer Science & Business Media. This book was released on 2013-11-19 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text. ​

Introduction to Toxicology, Third Edition

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Publisher : CRC Press
ISBN 13 : 9780415247634
Total Pages : 238 pages
Book Rating : 4.2/5 (476 download)

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Book Synopsis Introduction to Toxicology, Third Edition by : John Timbrell

Download or read book Introduction to Toxicology, Third Edition written by John Timbrell and published by CRC Press. This book was released on 2001-11-15 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

An Introduction to Interdisciplinary Toxicology

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Publisher : Academic Press
ISBN 13 : 0128136022
Total Pages : 644 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis An Introduction to Interdisciplinary Toxicology by : Carey N. Pope

Download or read book An Introduction to Interdisciplinary Toxicology written by Carey N. Pope and published by Academic Press. This book was released on 2020-02-21 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple” molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology.

Introduction to Toxicology and Food

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Publisher : CRC Press
ISBN 13 : 0849314569
Total Pages : 170 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Introduction to Toxicology and Food by : Tomris Altug

Download or read book Introduction to Toxicology and Food written by Tomris Altug and published by CRC Press. This book was released on 2002-07-30 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: With growing interest in the safety of foods, knowledge of food toxicology is gaining more importance every day. Introduction to Toxicology and Food provides a concise overview of both the science of toxicology and food toxicology. It presents easy-to-understand explanations of the concepts and principles of toxicology as a science, the toxicants found in foods, and naturally occurring antitoxic/anticarcinogenic substances in foods. It examines the uses, harmful effects, and safety aspects of a variety of toxicants, including natural toxicants, contaminants, and food additives. The book begins with a general overview of the concepts and principles of toxicology. It describes its history and branches, toxic doses, stages of toxication, effect mechanisms of toxins, and toxicity tests. Then it covers the substances in our foods that have toxicological significance, such as natural sources of toxicants, contaminants, and food additives. Finally, the book presents information about "chemopreventers" - those foods and food components that have antimutagenic or anticarcinogenic effects. With its easy-to-read style and its clear discussions of the science of toxicology, food toxicology, and chemopreventers, Introduction to Toxicology and Food is an ideal text for an undergraduate course in food toxicology and a useful guide for food scientists.

An Introduction to Aquatic Toxicology

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Publisher : Elsevier
ISBN 13 : 0124115810
Total Pages : 253 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis An Introduction to Aquatic Toxicology by : Mikko Nikinmaa

Download or read book An Introduction to Aquatic Toxicology written by Mikko Nikinmaa and published by Elsevier. This book was released on 2014-07-01 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Aquatic Toxicology is an introductory reference for all aspects of toxicology pertaining to aquatic environments. As water sources diminish, the need to understand the effects that contaminants may have on aquatic organisms and ecosystems increases in importance. This book will provide you with a solid understanding of aquatic toxicology, its past, its cutting-edge present and its likely future. An Introduction to Aquatic Toxicology will introduce you to the global issue of aquatic contamination, detailing the major sources of contamination, from where they originate, and their effects on aquatic organisms and their environment. State-of-the-art toxicological topics covered include nanotoxicology, toxicogenomics, bioinformatics, transcriptomics, metabolomics, as well as water management and the toxicological effects of major environmental issues such as algal blooms, climate change and ocean acidification. This book is intended for anyone who wants to know more about the impact of toxicants on aquatic organisms and ecosystems, or to keep up to date with recent and future developments in the field. - Provides with the latest perspectives on the impacts of toxicants on aquatic environments, such as nanotoxicology, toxicogenomics, ocean acidification and eutrophication - Offers a complete overview, beginning with the origins of aquatic toxicology and concluding with potential future challenges - Includes guidance on testing methods and a glossary of aquatic toxicology terms

Modern Poisons

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Publisher : Island Press
ISBN 13 : 1610913825
Total Pages : 224 pages
Book Rating : 4.6/5 (19 download)

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Book Synopsis Modern Poisons by : Alan Kolok

Download or read book Modern Poisons written by Alan Kolok and published by Island Press. This book was released on 2016-05-05 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Poisons bridges the gap between traditional toxicology textbooks and journal articles on cutting-edge science. This accessible book explains basic principles in plain language while illuminating the most important issues in contemporary toxicology. Kolok begins by exploring age-old precepts such as the dose-response relationship and goes on to show exactly how chemicals enter the body and elicit their toxic effect. Kolok then traces toxicology's development, from studies of endocrine-disrupting chemicals in toiletries to the emerging science on prions and epigenetics. Whether studying toxicology itself, public health, or environmental science, readers will develop a core understanding of--and curiosity about--this fast-changing field.

Introduction to Food Toxicology

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Publisher : Academic Press
ISBN 13 : 0080925774
Total Pages : 231 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Introduction to Food Toxicology by : Takayuki Shibamoto

Download or read book Introduction to Food Toxicology written by Takayuki Shibamoto and published by Academic Press. This book was released on 2012-12-02 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of food toxicology currently has a high profile of interest in the food industry, universities, and government agencies, and is certainly of great concern to consumers. There are many books which cover selected toxins in foods (such as plant toxins, mycotoxins, pesticides, or heavy metals), but this book represents the first pedagogic treatment of the entire range of toxic compounds found naturally in foods or introduced by industrial contamination or food processing methods. Featuring coverage of areas of vital concern to consumers, such as toxicological implications of food adulteration (as seen in ethylene glycol in wines or the Spanish olive oil disaster) or pesticide residues, Introduction to Food Toxicology will be of interest to students in toxicology, environmental studies, and dietetics as well as anyone interested in food sources and public health issues. The number of students who are interested in toxicology has increased dramatically in the past several years. Issues related to toxic materials have received more and more attention from the public. The issues and potential problems are reported almost daily by the mass media, including television, newspapers, and magazines. Major misunderstandings and confusion raised by those reports are generally due to lack of basic knowledge about toxicology among consumers. This textbook provides the basic principles of food toxicology in order to help the general public better understand the real problems of toxic materials in foods. - Principles of toxicology - Toxicities of chemicals found in foods - Occurrence of natural toxins in plant and animal foodstuffs - Food contamination caused by industry - Toxic chemicals related to food processing - Food additives - Microbial toxins in foods

Essentials of Toxicology for Health Protection

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Publisher : Oxford University Press
ISBN 13 : 9780199652549
Total Pages : 368 pages
Book Rating : 4.6/5 (525 download)

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Book Synopsis Essentials of Toxicology for Health Protection by : David Baker

Download or read book Essentials of Toxicology for Health Protection written by David Baker and published by Oxford University Press. This book was released on 2012-03-15 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Toxicology for Health Protection is a key handbook and course reader for all health protection professionals. It covers the basics of toxicology and its application to issues of topical concern including contaminated land, water pollution and traditional medicines.

Toxicology and Risk Assessment

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Publisher : John Wiley & Sons
ISBN 13 : 1119135923
Total Pages : 842 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Toxicology and Risk Assessment by : Helmut Greim

Download or read book Toxicology and Risk Assessment written by Helmut Greim and published by John Wiley & Sons. This book was released on 2018-08-10 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a complete understanding of how our bodies respond to toxicants, and the principles used to assess the health risks of specific exposure scenarios Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition reflects recent advances in science and technology, and provides the scientific background and methodological issues to enable the reader to understand the basic principles in toxicology and to evaluate the health risks of specific exposure scenarios. Completely updated with the latest information, this book offers a concise introduction to the subject. It is divided into five sections: Principles in Toxicology, Organ Toxicology, Methods in Toxicology, Regulatory Toxicology, and Specific Toxicity. The 2nd Edition adds new chapters that cover recent scientific and technological advances and current topics including the endocrine system, alternatives to animal testing, risk assessment and thresholds for carcinogens, European and international regulation, nanomaterials, fuels, fragrances, and agrochemicals. Concentrates on the basic concepts of toxicology and provides sufficient information for the reader to become familiar with them in order to understand the principles and to evaluate the risks at given exposures 30% new chapters cover recent scientific and technological advances including alternatives to animal testing; genotoxic carcinogens; REACH regulations; nanomaterials; fuels; fragrances; PAHs; and agrochemicals Written by a team of international specialists, and edited by two outstanding scientists in the field Fully updated and expanded, Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition is an essential text for any student or researcher with an interest in toxicology and related risk assessments.

Principles of Biochemical Toxicology, Third Edition

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Publisher : CRC Press
ISBN 13 : 9780748407378
Total Pages : 408 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Principles of Biochemical Toxicology, Third Edition by : John Timbrell

Download or read book Principles of Biochemical Toxicology, Third Edition written by John Timbrell and published by CRC Press. This book was released on 1999-10-21 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards. Following on from the acclaimed first two editions of Principles of Biochemical Toxicology, John Timbrell has expanded the text to include: summary sections questions and model answers thoroughly revised artwork These features, plus the new easy-to-read format will make biochemical toxicology more accessible to undergraduates and postgraduates coming across the subject for the first time, particularly when undertaking self-directed study. This comprehensive textbook provides a thorough explanation of dose-response relationships; disposition and metabolism; toxic responses to foreign compounds, and detailed examples to illustrate mechanisms of toxicity. There is also an expanded and updated bibliography, directing the reader to further reading if required. Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field, an essential aid to learning and teaching.

Environmental Sustainability for Engineers and Applied Scientists

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Publisher : Cambridge University Press
ISBN 13 : 1107166829
Total Pages : 261 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Environmental Sustainability for Engineers and Applied Scientists by : Greg Peters

Download or read book Environmental Sustainability for Engineers and Applied Scientists written by Greg Peters and published by Cambridge University Press. This book was released on 2019-03-14 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connects a qualitative perspective of environmental management with the quantitative skills used by engineering and applied science students.

A Textbook of Modern Toxicology

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Publisher : McGraw-Hill Medical Publishing
ISBN 13 :
Total Pages : 518 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A Textbook of Modern Toxicology by : Ernest Hodgson

Download or read book A Textbook of Modern Toxicology written by Ernest Hodgson and published by McGraw-Hill Medical Publishing. This book was released on 1997 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised edition reflects changes in the core curriculum subjects covered in the basic toxicology course for graduate students. Designed as an introductory textbook, it emphasizes the fundamental basis of toxic action at the cellular and molecular levels and lays the foundation for specialized courses in toxicology. Additional topics include metabolic activation and cellular protection, clinical toxicology diagnosis and treatment, ecosystems, environmental toxicology, ecotoxicology, case histories, and future consideration for environmental and human health.

A Comprehensive Guide to Toxicology in Preclinical Drug Development

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Publisher : Academic Press
ISBN 13 : 0123878160
Total Pages : 903 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis A Comprehensive Guide to Toxicology in Preclinical Drug Development by : Ali S. Faqi

Download or read book A Comprehensive Guide to Toxicology in Preclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2012-10-18 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. - Chapters written by world-renowned contributors who are experts in their fields - Includes the latest research in preclinical drug testing and international guidelines - Covers preclinical toxicology in small molecules and biologics in one single source

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

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Author :
Publisher : Academic Press
ISBN 13 : 0128036214
Total Pages : 988 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis A Comprehensive Guide to Toxicology in Nonclinical Drug Development by : Ali S. Faqi

Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2016-11-03 with total page 988 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. - Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more - Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules - Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology

Introduction to Environmental Toxicology

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Author :
Publisher : CABI
ISBN 13 : 1789245184
Total Pages : 165 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Introduction to Environmental Toxicology by : J.P.F. D'Mello

Download or read book Introduction to Environmental Toxicology written by J.P.F. D'Mello and published by CABI. This book was released on 2020-09-18 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Environmental Toxicology is designed as a concise text, introducing students to the fundamentals of this important subject. It covers the origin, characterization and environmental distribution of the major pollutants, and provides an explanation of their implications for human morbidity via the development of cancer, cardiovascular disease, pulmonary dysfunction and neurological conditions. Covering all the major biological toxins and pollutants, this book forms a true introduction to the subject for undergraduates studying environmental toxicology and related subjects.

Human Toxicology of Chemical Mixtures

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Author :
Publisher : William Andrew
ISBN 13 : 1437734642
Total Pages : 575 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Human Toxicology of Chemical Mixtures by : Harold Zeliger

Download or read book Human Toxicology of Chemical Mixtures written by Harold Zeliger and published by William Andrew. This book was released on 2011-06-24 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this important reference work, Zeliger catalogs the known effects of chemical mixtures on the human body and also proposes a framework for understanding and predicting their actions in terms of lipophile (fat soluble) / hydrophile (water soluble) interactions. The author's focus is on illnesses that ensue following exposures to mixtures of chemicals that cannot be attributed to any one component of the mixture. In the first part the mechanisms of chemical absorption at a molecular and macromolecular level are explained, as well as the body's methods of defending itself against xenobiotic intrusion. Part II examines the sources of the chemicals discusssed, looking at air and water pollution, food additives, pharmaceuticals, etc. Part III, which includes numerous case studies, examines specific effects of particular mixtures on particular body systems and organs and presents a theoretical framework for predicting what the effects of uncharacterized mixtures might be. Part IV covers regulatory requirements and the need to adjust recommended exposure levels for products containing mixtures. It also contains recommendations on how to limit exposure to mixtures in the products we use and on how to limit release of mixtures into the environment. Providing brief summaries of each mixture and its effects, Zeliger provides a comprehensive reference, a jumping off point for professionals (with extensive chapter bibliographies) and an introduction to the topic for those studying traditional toxicology. Addressing many inadequately understood illnesses and conditions such as asthma, infertility and cancer, it will also be of interest to health professionals, environmental scientists and lawyers. - Presents a theoretical framework for predicting the effects of chemical mixtures for which no specific data exists (this predictive aspect is important due to the vast number of different potential chemical combinations – far too many to comprehensively catalog) - A quick and convenient source of hard to come by data on the rapidly developing field of chemical mixtures, for groups including chemists and engineers, toxicologists, health professionals and environmental scientists - New and updated material comprises over 30% of this timely new edition, which includes the latest research data alongside an expanded introduction to the science and art of predicting the toxicological properties of chemical mixtures

Introduction to Environmental Toxicology

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Publisher :
ISBN 13 : 9781498750424
Total Pages : 0 pages
Book Rating : 4.7/5 (54 download)

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Book Synopsis Introduction to Environmental Toxicology by : Wayne G. Landis

Download or read book Introduction to Environmental Toxicology written by Wayne G. Landis and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to environmental toxicology -- Frameworks and paradigms for environmental toxicology -- Overview of toxicity testing methods -- The analysis of exposure-response -- The fate and transport of contaminants -- Uptake and modes of action -- Modification in toxic responses, mixtures and climate change -- Inorganic gaseous pollutants -- Fluoride as a contaminant of developing economies -- Metals -- Biotransformation, detoxification, and biodegradation -- Ecological effects from biomarkers to populations -- Ecological effects: community to landscape scales of toxicological impacts -- Ecological risk assessment -- Index.