Intravenous Thrombolysis For Suspected Ischemic Stroke With Seizure At Onset

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Intravenous Thrombolysis For Suspected Ischemic Stroke With Seizure At Onset

Author : Stefan Engelter
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (125 download)

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Book Synopsis Intravenous Thrombolysis For Suspected Ischemic Stroke With Seizure At Onset by : Stefan Engelter

Download or read book Intravenous Thrombolysis For Suspected Ischemic Stroke With Seizure At Onset written by Stefan Engelter and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: ObjectiveSeizure at onset (SaO) has been considered a relative contraindication for intravenous thrombolysis (IVT) in patients with acute ischemic stroke, although this appraisal is not evidence-based. Here, we investigated the prognostic significance of SaO in patients treated with IVT for suspected ischemic stroke. MethodsIn this multicenter, IVT-registry-based study we assessed the association between SaO and symptomatic intracranial hemorrhage (sICH, ECASS-II definition), 3-month mortality and 3-month functional outcome on the modified Rankin Scale (mRS) using unadjusted and adjusted logistic regression, coarsened exact matching and inverse probability weighted analyses. ResultsAmong 10,074 IVT-treated patients, 146 (1.5%) had SaO. SaO patients had significantly higher NIHSS and glucose on admission and more often female sex, prior stroke and prior functional dependence than non-SaO patients. In unadjusted analysis, they had generally less favorable outcomes. After controlling for confounders in adjusted, matched and weighted analyses, all associations between SaO and any of the outcomes disappeared, including sICH (odds ratio [OR]unadjusted 1.53 [95% confidence interval: 0.74,3.14], ORadjusted 0.52[0.13,2.16], ORmatched 0.68[0.15,3.03], ORweighted 0.95[0.39,2.32]), mortality (ORunadjusted 1.49[1.00,2.24], ORadjusted 0.98[0.5,1.92], ORmatched 1.13[0.55,2.33], ORweighted 1.17[0.73,1.88]) and functional outcome (mRSu22653 / ordinal mRS: ORunadjusted 1.33[0.96,1.84] / 1.35[1.01,1.81], ORadjusted 0.78[0.45,1.32] / 0.78[0.52,1.16], ORmatched 0.75[0.43,1.32] / 0.45[0.10,2.06], ORweighted 0.87[0.57,1.34] / 1.00[0.66,1.52]). These results were consistent regardless of whether patients had an eventual diagnosis of ischemic stroke (89/146) or stroke mimic (57/146 SaO patients). InterpretationSaO was not an independent predictor of poor prognosis. Withholding IVT from patients with assumed ischemic stroke presenting with SaO seems unjustified.

Thrombolytic Therapy for Acute Stroke

Author : Patrick D. Lyden
Publisher : Springer Science & Business Media
ISBN 13 : 1592599338
Total Pages : 372 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Thrombolytic Therapy for Acute Stroke by : Patrick D. Lyden

Download or read book Thrombolytic Therapy for Acute Stroke written by Patrick D. Lyden and published by Springer Science & Business Media. This book was released on 2007-11-08 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: It often takes time for a new therapeutic modality to mature into an accepted treatment option. After initial approval, new drugs, devices, and procedures all go through this process until they become “vetted” by the scientific community as well as the medical community at large. Thrombolysis for treatment of stroke is no exception. Thrombolytic Therapy for Acute Stroke, Second Edition comes four years after the first edition and provides a very comprehensive, updated perspective on the use of intravenous rt-TPA in acute stroke. The authors provide longer term follow-up on the pivotal clinical trials that led to Food and Drug Administration approval, data concerning phase 4 trials in larger numbers of patients, and, most importantly, the community experience that has accumulated since its release. They add to this the latest promising information concerning intra-arterial thrombolysis, which is still under investigation and more speculative sections concerning possible new avenues of clinical research such as combining intravenous thr- bolysis with neuroprotective therapies or intra-arterial thrombolysis. A wealth of factual information is supplemented by chapters containing sage opinion from Drs. Lyden and Caplan concerning the logistical, economic, and procedural issues that have been generated since the advent of this technology. Importantly, diagnosis does not take a back seat to therapeutics as illustrated by sections devoted to eva- ation of the stroke patient, very useful illustrative cases and clinical comments, and chapters on the latest in imaging as applied to this field.

Acute Stroke Nursing

Author : Jane Williams
Publisher : John Wiley & Sons
ISBN 13 : 1118699629
Total Pages : 367 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Acute Stroke Nursing by : Jane Williams

Download or read book Acute Stroke Nursing written by Jane Williams and published by John Wiley & Sons. This book was released on 2013-05-07 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a medical emergency that requires immediate medical attention. With active and efficient nursing management in the initial hours after stroke onset and throughout subsequent care, effective recovery and rehabilitation is increased. Acute Stroke Nursing provides an evidence-based, practical text facilitating the provision of optimal stroke care during the primary prevention, acute and continuing care phases. This timely and comprehensive text is structured to follow the acute stroke pathway experienced by patients. It explores the causes, symptoms and effects of stroke, and provides guidance on issues such as nutrition, continence, positioning, mobility and carer support. The text also considers rehabilitation, discharge planning, palliative care and the role of the nurse within the multi-professional team. Acute Stroke Nursing is the definitive reference on acute stroke for all nurses and healthcare professionals wishing to extend their knowledge of stroke nursing. Evidence-based and practical in style, with case studies and practice examples throughout Edited and authored by recognised stroke nursing experts, clinicians and leaders in the field of nursing practice, research and education The first text to explore stroke management from UK and international perspectives, and with a nursing focus

Intravenous Thrombolysis at 3-4.5 Hours After Acute Ischemic Stroke: A Retrospective Multi-center Observational Study in Taiwan

Author : Jeng Jiann-Shing
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Intravenous Thrombolysis at 3-4.5 Hours After Acute Ischemic Stroke: A Retrospective Multi-center Observational Study in Taiwan by : Jeng Jiann-Shing

Download or read book Intravenous Thrombolysis at 3-4.5 Hours After Acute Ischemic Stroke: A Retrospective Multi-center Observational Study in Taiwan written by Jeng Jiann-Shing and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Background: Intravenous thrombolysis with alteplase 3 to 4.5 hours after ischemic stroke onset has been proved by a randomized trial and recommended by several guidelines. However, it is still an off-label treatment in many countries, including Taiwan. The present study aimed to investigate the effectiveness and safety of alteplase administered between 3 and 4.5 hours after stroke onset by a retrospective observational study.Methods: Multi-center stroke registry has been well undertaken in Taiwan since 2006. Based on Taiwan Stroke Registry, we included ischemic stroke patients who received intravenous thrombolysis with alteplase 3 to 4.5 hours after onset of a stroke into analysis. Patients who received superimposed endovascular treatment, or enrolled in acute stroke treatment trials were excluded. Age-and-sex matched controls were also selected as the following criteria: onset to hospital arrival 2-4.5 hours, no absolute contraindication for thrombolytic therapy, and no use of any thrombolytic agents or endovascular treatment. The effectiveness was evaluated by a favorable outcome at 3 months, modified Rankin scale 0 or 1, and safety was determined by symptomatic intracranial hemorrhage (ICH) and mortality at 3 months.Results: A total of 748 patients were recruited from 16 hospitals, including 374 (67% men, mean age, 67.8+12.5 years) in the alteplase group and 374 (67% men, mean age, 66.1+13.2 years) in the control group. Patients in the alteplase group had more favorable outcome than in the control group (34.0% vs. 22.7%; odds ratio [OR], 1.75; 95% confidence interval [CI], 1.27-2.42; P=0.001). There was no significant difference of symptomatic ICH (alteplase, 5.6% vs. control 2.9%, OR, 1.96; 95% CI, 0.93-4.13; P=0.076), and mortality (alteplase, 7.8% vs. control 7.5%; OR, 1.04; 95% CI, 0.61-1.78; P=0.89) between two groups. Compared to patients received standard dose of alteplase (n=182), those with reduced dose of alteplase (n=192) did not have lower hemorrhagic transformation and better functional outcome.Conclusion: The effectiveness and safety of intravenous alteplase administration 3 to 4.5 hours after stroke onset was confirmed in this retrospective analysis in Taiwan.

The Stroke Book

Author : Michel T. Torbey
Publisher : Cambridge University Press
ISBN 13 : 1107634725
Total Pages : 395 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis The Stroke Book by : Michel T. Torbey

Download or read book The Stroke Book written by Michel T. Torbey and published by Cambridge University Press. This book was released on 2013-07-18 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential companion for busy professionals seeking to navigate stroke-related clinical situations successfully and make quick informed treatment decisions.

Acute Ischemic Stroke

Author : R. Gilberto González
Publisher : Springer Science & Business Media
ISBN 13 : 3642127517
Total Pages : 299 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Acute Ischemic Stroke by : R. Gilberto González

Download or read book Acute Ischemic Stroke written by R. Gilberto González and published by Springer Science & Business Media. This book was released on 2010-10-05 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.

Textbook of Stroke Medicine

Author : Michael Brainin
Publisher : Cambridge University Press
ISBN 13 : 1107047498
Total Pages : 425 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Textbook of Stroke Medicine by : Michael Brainin

Download or read book Textbook of Stroke Medicine written by Michael Brainin and published by Cambridge University Press. This book was released on 2014-09-11 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.

ICU Protocols

Author : Rajesh Chawla
Publisher : Springer Nature
ISBN 13 : 9811508984
Total Pages : 613 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis ICU Protocols by : Rajesh Chawla

Download or read book ICU Protocols written by Rajesh Chawla and published by Springer Nature. This book was released on 2019-12-31 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this highly successful book includes up-to-date notes on the step-wise management of clinical emergencies encountered in everyday intensive care units (ICU). Each thoroughly revised chapter provides concise information for point-of-care treatment, making it a practical guide clinicians can refer to on a daily basis at work or while traveling, or just to expand their knowledge. Volume 1 of ICU Protocols covers topics in pulmonology, cardiology, neurology, gastroenterology, nephrology and infectious diseases. The endocrine and metobolic systems, oncology, trauma, toxicology, envenomation and thermodysregulation, obstetrics, and perioperative care are covered in the second volume of ICU Protocols. This two-volume book is a must-read for intensivists, critical care specialists, junior trainees and residents working in ICUs. It is also relevant as course material for workshops on critical care, and essential for all hospital-based libraries. “This book provides junior trainees with an introduction to the management of problems common to the critical care unit.” David J Dries, Doody’s Book Reviews, March, 2013, for the first edition of ICU Protocols.

Diseases of the Brain, Head and Neck, Spine 2020–2023

Author : Juerg Hodler
Publisher : Springer Nature
ISBN 13 : 303038490X
Total Pages : 252 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler

Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Transient Ischemic Attack and Stroke

Author : Sarah T. Pendlebury
Publisher : Cambridge University Press
ISBN 13 : 0521735122
Total Pages : 407 pages
Book Rating : 4.5/5 (217 download)

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Book Synopsis Transient Ischemic Attack and Stroke by : Sarah T. Pendlebury

Download or read book Transient Ischemic Attack and Stroke written by Sarah T. Pendlebury and published by Cambridge University Press. This book was released on 2009-02-19 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accessible handbook covering the investigation, diagnosis and management of transient ischemic attacks and minor strokes.

Stroke in Childhood

Author : Paediatric Stroke Working Group
Publisher : Royal College of Physicians
ISBN 13 : 1860162363
Total Pages : 82 pages
Book Rating : 4.8/5 (61 download)

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Book Synopsis Stroke in Childhood by : Paediatric Stroke Working Group

Download or read book Stroke in Childhood written by Paediatric Stroke Working Group and published by Royal College of Physicians. This book was released on 2004 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke occuring in childhood although less common, presents serious challenges. This guideline is based on the expertise of a multidisciplinary working group and include the views of patients, parents and families.

Prehospital Care of Neurologic Emergencies

Author : Todd Crocco
Publisher : Cambridge University Press
ISBN 13 : 1139993607
Total Pages : 213 pages
Book Rating : 4.1/5 (399 download)

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Book Synopsis Prehospital Care of Neurologic Emergencies by : Todd Crocco

Download or read book Prehospital Care of Neurologic Emergencies written by Todd Crocco and published by Cambridge University Press. This book was released on 2014-07-24 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prehospital Care of Neurologic Emergencies is a reliable and definitive resource for emergency medical services personnel at multiple levels: physicians, paramedics, nurses and others who encounter these critically ill patients. This focused and succinct book addresses the management of a wide range of neurologic emergencies, including traumatic brain injuries, spinal cord injuries, strokes, and seizures. In these emergencies time is critical, and the simply presented, straightforward format of the patient care and management recommendations help readers to treat patients rapidly and confidently. Each chapter follows a standard format that includes an overview of each neurologic emergency, important background, key challenges, and areas requiring future investigation. This book is unlikely to be placed on your bookshelf; instead, you will keep it nearby for times when you face life-threatening neurologic emergencies. When seconds count, this book has the answers.

Cerebral Small Vessel Disease

Author : Leonardo Pantoni
Publisher : Cambridge University Press
ISBN 13 : 1107031664
Total Pages : 375 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Cerebral Small Vessel Disease by : Leonardo Pantoni

Download or read book Cerebral Small Vessel Disease written by Leonardo Pantoni and published by Cambridge University Press. This book was released on 2014-05 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.

Ischemic Stroke

Author : Giuseppe D’Aliberti
Publisher : Springer
ISBN 13 : 3319317059
Total Pages : 103 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Ischemic Stroke by : Giuseppe D’Aliberti

Download or read book Ischemic Stroke written by Giuseppe D’Aliberti and published by Springer. This book was released on 2016-11-22 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed practical guidance on the management of acute ischemic stroke in the clinical settings encountered in daily practice. Real-life cases are used to depict a wide range of clinical scenarios and to highlight significant aspects of management of ischemic stroke. In addition, diagnostic and therapeutic protocols are presented and helpful decision-making algorithms are provided that are specific to the different professionals involved in delivery of acute stroke care and to differing types of hospital facility. The coverage is completed by the inclusion of up-to-date scientific background information relevant to diagnosis and therapy. Throughout, the approach adopted is both practical and multidisciplinary. The book will be of value for all practitioners involved in the provision of acute stroke care, and also for medical students.

Critical Care of the Stroke Patient

Author : Stefan Schwab
Publisher : Cambridge University Press
ISBN 13 : 1139991558
Total Pages : 579 pages
Book Rating : 4.1/5 (399 download)

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Book Synopsis Critical Care of the Stroke Patient by : Stefan Schwab

Download or read book Critical Care of the Stroke Patient written by Stefan Schwab and published by Cambridge University Press. This book was released on 2014-06-05 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: New and groundbreaking therapeutic options for the critical care of patients with cerebrovascular disease have improved patient management, minimized morbidity, reduced in-patient care, improved quality of life, and had a positive economic impact on health service provision. This volume integrates these approaches and suggests the best therapy option for all cerebrovascular conditions. The early chapters of the book focus on monitoring techniques and interventions. Subsequent sections address the critical care of a wide range of cerebrovascular diseases: ischemic stroke, intracranial hemorrhage, subarachnoid hemorrhage, arteriovenous malformations, cerebral venous thrombosis and traumatic injury. The editors and authors are internationally recognized experts in their field, and the text is supplemented by tables and illustrations to demonstrate important clinical findings. This book will meet the needs of stroke physicians, neurologists, neurosurgeons, neurointensivists and interventional neuroradiologists seeking to maximize positive outcomes for their patients.

New Antiepileptic Drugs

Author : Francesco Pisani
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis New Antiepileptic Drugs by : Francesco Pisani

Download or read book New Antiepileptic Drugs written by Francesco Pisani and published by Elsevier Publishing Company. This book was released on 1991 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmacological fight against epilepsy began many centuries ago when Hippocrates discovered that the cause of epilepsy is natural, as opposed to supernatural and, as a consequence, must be treated with a natural remedy. Even though science has significantly progressed since that era, the challenge to find remedies for epilepsy is ever present. The aim of this particular volume is to offer an up-to-date review of the most recent advances in antiepileptic drug development, considered from various viewpoints: (i) general, by taking into account the size of refractory epilepsy and its related problems; (ii) experimental, by exploring the mechanisms of epileptogenesis and the possiblility of influencing it through drugs, and (iii) clinical, by describing the results obtained with compounds currently at an advanced stage of testing.

Clinical Electroencephalography

Author : Oriano Mecarelli
Publisher : Springer
ISBN 13 : 3030045730
Total Pages : 822 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Clinical Electroencephalography by : Oriano Mecarelli

Download or read book Clinical Electroencephalography written by Oriano Mecarelli and published by Springer. This book was released on 2019-06-06 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the developments and improvements in electroencephalography (EEG). In recent years, digital technology has replaced analog equipments, and it is now possible to easily record and store EEG tracings and to quickly recall previously acquired material for subsequent analysis. In addition, not only static figures, but also electronic supplementary materials can be included in books, enabling EEGs to be viewed in real-time. In clinical practice, EEG still represents the most important functional examination in the study CNS development and its anatomical and physiological integrity throughout life. In the pathological context, EEG provides indispensable diagnostic information for classification of epileptic syndromes, and it is also valuable in all the other CNS diseases (infectious, cerebrovascular, neurodegenerative, etc). Furthermore, monitoring EEG can be widely used in emergency settings, such as emergency departments or intensive care units. In comatose patients, EEG provides information regarding prognosis and evaluation of the sedative effect of anesthetic drugs. Written by a group of leading national and international experts, it offers a substantial, yet practical, EEG compendium, which serves as a reference resource for physicians and neurodiagnostic technologists as well as physicians-in-training, researchers, practicing electroencephalographers and students.