Author : Joyce Mounir Maalouf
Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.:/5 (787 download)
Book Synopsis Interaction Between Dietary Calcium, Exercise and Leptin and Their Impact on Musculoskeletal Parameters in Children and Adolescents by : Joyce Mounir Maalouf
Download or read book Interaction Between Dietary Calcium, Exercise and Leptin and Their Impact on Musculoskeletal Parameters in Children and Adolescents written by Joyce Mounir Maalouf and published by . This book was released on 2007 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lifestyle factors, namely nutrition and physical activity, are known to be invol ved in bone mass acquisition during childhood to optimize peak bone mineral accr etion. Serum leptin, a marker of total body fat, and bone mass are also concorda nt in several respects. Few studies have investigated the relationship between s erum leptin and bone mineral in youth in the context of other mediators of bone mineral accretion. The purpose of the present investigation is to determine the impact of exercise, dietary calcium intake and leptin on bone mass and body composition in 363 heal thy Lebanese school children and adolescents (184 boys and 179 girls), aged 10-1 7 years. There was a sexual dimorphism in serum leptin concentrations with girls having h igher leptin levels than boys across all pubertal stages. In a linear regression model, after adjusting for height, puberty stages, lean mass, fat mass, exercis e, dietary calcium intake, vitamin D and IGF1, leptin was an independent predict or of BMD at the femoral neck, trochanter, total hip and total body in girls onl y. Physical activity was a consistent and independent predictor of BMC and BMD a t the 3 hip sites and total body in boys explaining 7% of the variability in BMD and 3.5% of the variability in BMC. Dietary calcium intake accounted for 5% of radius BMD variability in boys only. There seem to be a relationship between lifestyle factors, the hormonal milieu and bone mineral mass in puberty. These findings suggest the need for the develo pment of public health strategies in the alteration of diet and exercise lifesty les to optimize musculoskeletal health in youth. Results also show a distinct se xual dimorphism in the impact of leptin and lifestyle factors on musculoskeletal outcomes; the basis for these gender differences is unclear and deserves furthe r investigation.