Impact Of Molecular Biology And New Technical Developments On Diagnostic Imaging

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Impact of Molecular Biology and New Technical Developments in Diagnostic Imaging

Author : W. Semmler
Publisher : Springer Science & Business Media
ISBN 13 : 3642608442
Total Pages : 304 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Impact of Molecular Biology and New Technical Developments in Diagnostic Imaging by : W. Semmler

Download or read book Impact of Molecular Biology and New Technical Developments in Diagnostic Imaging written by W. Semmler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: New developments in the field of high resolution imaging focus on functional parameters pertaining to disease-specific medical imaging. Such new diagnostic strategies are possible using scintigraphic techniques and, more recently, by MRI and US. In addition, new therapeutic concepts, including gene therapy, require specific tracers or contrast media for therapy monitoring, for example, enzyme activity and changes in receptor expression. For this purpose scientists conducting basic research, expecially molecular biologists, and clinicians must collaborate in order to exploit the available interdisciplinary knowledge in the development of new imaging technologies so as to incorporate the molecular signals of diseases.

Impact of Molecular Biology and New Technical Developments on Diagnostic Imaging

Author : W. Semmler
Publisher : Springer Verlag
ISBN 13 : 9780387631110
Total Pages : 268 pages
Book Rating : 4.6/5 (311 download)

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Book Synopsis Impact of Molecular Biology and New Technical Developments on Diagnostic Imaging by : W. Semmler

Download or read book Impact of Molecular Biology and New Technical Developments on Diagnostic Imaging written by W. Semmler and published by Springer Verlag. This book was released on 1997-01-01 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:

From Morphological Imaging to Molecular Targeting

Author : Markus Schwaiger
Publisher : Springer Science & Business Media
ISBN 13 : 3662073102
Total Pages : 218 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis From Morphological Imaging to Molecular Targeting by : Markus Schwaiger

Download or read book From Morphological Imaging to Molecular Targeting written by Markus Schwaiger and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current progress in molecular medicine allows the identification of a plethora of new and often human-specific drug targets. An early in vivo validation of specific ligands binding to these targets in humans is needed to assess their potential for targeted imaging and radiotherapy. Radiopharmaceuticals are uniquely suitable for such target validation studies. The purpose of the Ernst Schering Research Foundation Workshop 48 was to offer a forum for an open exchange on the state of the art in the early development of such radiopharmaceuticals. Experts from academia, industry and regulatory authorities provided contributions covering the identification of targets, the necessary preclinical studies on the safety of ligands as well as their validation in human clinical trials.

Make Life Visible

Author : Yoshiaki Toyama
Publisher : Springer Nature
ISBN 13 : 9811379084
Total Pages : 292 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Make Life Visible by : Yoshiaki Toyama

Download or read book Make Life Visible written by Yoshiaki Toyama and published by Springer Nature. This book was released on 2019-10-02 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.

Molecular Imaging: Basic Principles And Applications In Biomedical Research (2nd Edition)

Author : Markus Rudin
Publisher : World Scientific
ISBN 13 : 1783263172
Total Pages : 618 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis Molecular Imaging: Basic Principles And Applications In Biomedical Research (2nd Edition) by : Markus Rudin

Download or read book Molecular Imaging: Basic Principles And Applications In Biomedical Research (2nd Edition) written by Markus Rudin and published by World Scientific. This book was released on 2013-07-04 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The final chapter deals with visualization of cell migration, for example in the context of cell therapies.The second edition covers novel developments over recent years, in particular regarding imaging technologies (hybrid techniques) and novel reporter concepts. Novel biomedical applications have been included, where appropriate. All the chapters have been thoroughly reworked and the artwork updated.

Molecular Imaging

Author : Markus Rudin
Publisher :
ISBN 13 : 9781848168565
Total Pages : 593 pages
Book Rating : 4.1/5 (685 download)

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Book Synopsis Molecular Imaging by : Markus Rudin

Download or read book Molecular Imaging written by Markus Rudin and published by . This book was released on 2013 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today. This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological or structural response of the organism studied. The final chapter deals with visualization of cell migration, for example in the context of cell therapies. The second edition covers novel developments over recent years, in particular regarding imaging technologies (hybrid techniques) and novel reporter concepts. Novel biomedical applications have been included, where appropriate. All the chapters have been thoroughly reworked and the artwork updated.

Molecular Imaging: Basic Principles And Applications In Biomedical Research (3rd Edition)

Author : Markus Rudin
Publisher : World Scientific
ISBN 13 : 1786346869
Total Pages : 801 pages
Book Rating : 4.7/5 (863 download)

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Book Synopsis Molecular Imaging: Basic Principles And Applications In Biomedical Research (3rd Edition) by : Markus Rudin

Download or read book Molecular Imaging: Basic Principles And Applications In Biomedical Research (3rd Edition) written by Markus Rudin and published by World Scientific. This book was released on 2020-04-04 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied.The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added.

Imaging in Biological Research, Part A

Author :
Publisher : Elsevier
ISBN 13 : 0080497233
Total Pages : 440 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Imaging in Biological Research, Part A by :

Download or read book Imaging in Biological Research, Part A written by and published by Elsevier. This book was released on 2004-07-10 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses current methods in biological imaging, including extensive sections on MRI, CAT, NMR, PET and other imaging techniques.

Nanoparticles in Biomedical Imaging

Author : Jeff W.M. Bulte
Publisher : Springer Science & Business Media
ISBN 13 : 0387720278
Total Pages : 521 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Nanoparticles in Biomedical Imaging by : Jeff W.M. Bulte

Download or read book Nanoparticles in Biomedical Imaging written by Jeff W.M. Bulte and published by Springer Science & Business Media. This book was released on 2007-11-22 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current generation of imaging nanoparticles is diverse and dependent on its myriad of applications. This book provides an overview of how these imaging particles can be designed to fulfill specific requirements for applications across different imaging modalities. It presents, for the first time, a comprehensive interdisciplinary overview of the impact nanoparticles have on biomedical imaging and is a common central resource for researchers and teachers.

In Vivo Cellular and Molecular Imaging

Author : Eric T. Ahrens
Publisher : Gulf Professional Publishing
ISBN 13 : 9780121531706
Total Pages : 310 pages
Book Rating : 4.5/5 (317 download)

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Book Synopsis In Vivo Cellular and Molecular Imaging by : Eric T. Ahrens

Download or read book In Vivo Cellular and Molecular Imaging written by Eric T. Ahrens and published by Gulf Professional Publishing. This book was released on 2005-11-09 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent times there has been an explosive expansion of new imaging methodologies that are capable of visualizing specific populations of cells and molecular events in vivo. Vital imaging enhances our ability to study animal models of human development and disease, such as cancers, cardiovascular disease, diabetes, and Alzheimer's. Furthermore, non-invasive imaging may ultimately be useful for monitoring new generations of clinical molecular and cellular therapeutics, such as those utilizing viral vectors and stem cells. These new capabilities have been facilitated by the development of new imaging probes or reagents that target specific cell types, are chemically responsive to physiology, or are responsive to the presence of specific molecules, such as nucleic acids or enzymes. This volume provides an introduction to some of the most exciting methods and applications of emerging non-invasive imaging technologies using magnetic resonance imaging (MRI), positron emission tomography (PET), and various biophotonic approaches. Highlighted, are recent developments in reagent design that impart unique abilities to these imaging modalities to elucidate biological processes in vivo. * Includes 9 chapters by expert researchers in the field of imaging * Introduces new methods and applications of non-invasive imaging technologies * Covers ermerging topics in imaging such as in vivo cell cancer cells, imaging of autoimmune diseases, and maganetic resonance imaging

Opportunities in Biology

Author : National Research Council
Publisher : National Academies
ISBN 13 : 0309039274
Total Pages : 471 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Opportunities in Biology by : National Research Council

Download or read book Opportunities in Biology written by National Research Council and published by National Academies. This book was released on 1989-01-01 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologiesâ€"recombinant DNA, scanning tunneling microscopes, and moreâ€"are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needsâ€"for funding, effective information systems, and other supportâ€"of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies.

Advances in Cell and Molecular Diagnostics

Author : P.B. Raghavendra
Publisher : Academic Press
ISBN 13 : 0128136804
Total Pages : 300 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Advances in Cell and Molecular Diagnostics by : P.B. Raghavendra

Download or read book Advances in Cell and Molecular Diagnostics written by P.B. Raghavendra and published by Academic Press. This book was released on 2018-01-02 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cell and Molecular Diagnostics brings the scientific advances in the translation and validation of cellular and molecular discoveries in medicine into the clinical diagnostic setting. It enumerates the description and application of technological advances in the field of cellular and molecular diagnostic medicine, providing an overview of specialized fields, such as biomarker, genetic marker, screening, DNA-profiling, NGS, cytogenetics, transcriptome, cancer biomarkers, prostate specific antigen, and biomarker toxicologies. In addition, it presents novel discoveries and clinical pathologic correlations, including studies in oncology, infectious diseases, inherited diseases, predisposition to disease, and the description or polymorphisms linked to disease states. This book is a valuable resource for oncologists, practitioners and several members of the biomedical field who are interested in understanding how to apply cutting-edge technologies into diagnostics and healthcare. - Encompasses the current scientific advances in the translation and validation of cellular and molecular discoveries into the clinical diagnostic setting - Explains the application of cellular and molecular diagnostics methodologies in clinical trials - Focuses on translating preclinical tests to the bedside in order to help readers apply the most recent technologies to healthcare

Advancing Nuclear Medicine Through Innovation

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309134153
Total Pages : 173 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council

Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

The Chemistry of Imaging Probes

Author : Lorenzo Tei
Publisher : Frontiers Media SA
ISBN 13 : 288945598X
Total Pages : 129 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis The Chemistry of Imaging Probes by : Lorenzo Tei

Download or read book The Chemistry of Imaging Probes written by Lorenzo Tei and published by Frontiers Media SA. This book was released on 2018-10-19 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decades, the field of molecular imaging has been rapidly growing involving multiple disciplines such as medicine, biology, chemistry, pharmacology and biomedical engineering. Any molecular imaging procedure requires an imaging probe that is an agent used to visualize, characterize and quantify biological processes in living systems. Such a probe typically consists of an agent that usually produces signal for imaging purpose, a targeting moiety, and a linker connecting the targeting moiety and the signaling agent. Many challenging problems of molecular imaging can be addressed by exploiting the great possibilities offered by modern synthetic organic and coordination chemistry and the powerful procedures provided by conjugation chemistry. Thus, chemistry plays a decisive role in the development of this cutting-edge methodology. Currently, the diagnostic imaging modalities include Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Ultrasound (US), Nuclear Imaging (PET, SPECT), Optical Imaging (OI) and Photoacoustic Imaging (PAI). Each of these imaging modalities has its own advantages and disadvantages, and therefore, a multimodal approach combining two techniques is often adopted to generate complementary anatomical and functional information of the disease. The basis for designing imaging probes for a given application is dictated by the chosen imaging modality, which in turn is dependent upon the concentration and localization profile (vascular, extracellular matrix, cell membrane, intracellular, near or at the cell nucleus) of the target molecule. The development of high-affinity ligands and their conjugation to the targeting vector is also one of the key steps for pursuing efficient molecular imaging probes. Other excellent reviews, text and monographs describe the principles of biomedical imaging, focusing on molecular biology or on the physics behind the techniques. This Research Topic aims to show how chemistry can offer molecular imaging the opportunity to express all its potential.

Ovarian Cancer: Molecular & Diagnostic Imaging and Treatment Strategies

Author : Heide Schatten
Publisher : Springer Nature
ISBN 13 : 3030733599
Total Pages : 181 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Ovarian Cancer: Molecular & Diagnostic Imaging and Treatment Strategies by : Heide Schatten

Download or read book Ovarian Cancer: Molecular & Diagnostic Imaging and Treatment Strategies written by Heide Schatten and published by Springer Nature. This book was released on 2021-08-02 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book on Molecular & Diagnostic Imaging and Treatment Strategies of ovarian cancer is one of two companion books with the second one being focused on Cell and Molecular Biology of Ovarian Cancer. Both books include new exciting aspects of ovarian cancer research with chapters written by experts in their respective fields who contributed their unique expertise in specific ovarian cancer research areas and include cell and molecular details that are important for the specific subtopics. Comprehensive and concise reviews are included of key topics in the field.

Imaging in CNS Drug Discovery and Development

Author :
Publisher :
ISBN 13 : 9781441901354
Total Pages : 416 pages
Book Rating : 4.9/5 (13 download)

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Book Synopsis Imaging in CNS Drug Discovery and Development by :

Download or read book Imaging in CNS Drug Discovery and Development written by and published by . This book was released on 2011-07-11 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomedical Imaging Instrumentation

Author : Mrutyunjay Suar
Publisher : Elsevier
ISBN 13 : 0323856500
Total Pages : 238 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Biomedical Imaging Instrumentation by : Mrutyunjay Suar

Download or read book Biomedical Imaging Instrumentation written by Mrutyunjay Suar and published by Elsevier. This book was released on 2021-12-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Imaging Instrumentation: Applications in Tissue, Cellular and Molecular Diagnostics provides foundational information about imaging modalities, reconstruction and processing, and their applications. The book provides insights into the fundamental of the important techniques in the biomedical imaging field and also discusses the various applications in the area of human health. Each chapter summarizes the overview of the technique, the various applications, and the challenges and recent innovations occurring to further improve the technique. Chapters include Biomedical Techniques in Cellular and Molecular Diagnostics, The Role of CT Scan in Medical and Dental Imaging, Ultrasonography - Technology & Applications in Clinical Radiology, Magnetic Resonance Imaging, Instrumentation and Utilization of PET-CT Scan in Oncology, Gamma Camera and SPECT, Sentinel of Breast Cancer Screening; Hyperspectral Imaging; PA Imaging; NIR Spectroscopy, and The Advances in Optical Microscopy and its Applications in Biomedical Research. This book is ideal for supporting learning, and is a key resource for students and early career researchers in fields such as medical imaging and biomedical instrumentation. A basic, fundamental, easy to understand introduction to medical imaging techniques Each technique is accompanied with detailed discussion on the application in the biomedical field in an accessible and easy to understand way Provides insights into the limitations of each technology and innovations that are occurring related to that technology