Immunohistochemical Expression Study of Pro-apoptotic BH3-only Protein Bad in Canine Non-neoplastic Tissues and Canine Lymphomas

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Publisher :
ISBN 13 :
Total Pages : 27 pages
Book Rating : 4.:/5 (861 download)

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Book Synopsis Immunohistochemical Expression Study of Pro-apoptotic BH3-only Protein Bad in Canine Non-neoplastic Tissues and Canine Lymphomas by : Martina Andrea Dettwiler

Download or read book Immunohistochemical Expression Study of Pro-apoptotic BH3-only Protein Bad in Canine Non-neoplastic Tissues and Canine Lymphomas written by Martina Andrea Dettwiler and published by . This book was released on 2013 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunohistochemical Expression of Bax and Bak in Canine Non-neoplastic Tissues

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Publisher :
ISBN 13 :
Total Pages : 30 pages
Book Rating : 4.:/5 (87 download)

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Book Synopsis Immunohistochemical Expression of Bax and Bak in Canine Non-neoplastic Tissues by : Martina Croci

Download or read book Immunohistochemical Expression of Bax and Bak in Canine Non-neoplastic Tissues written by Martina Croci and published by . This book was released on 2013 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Evaluation of Valosin Containing Protein (P97) as a Cancer Biomaker in Canine Lymphomas

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (13 download)

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Book Synopsis Evaluation of Valosin Containing Protein (P97) as a Cancer Biomaker in Canine Lymphomas by : Sabin Dragos Filimon

Download or read book Evaluation of Valosin Containing Protein (P97) as a Cancer Biomaker in Canine Lymphomas written by Sabin Dragos Filimon and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 2214 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 2214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Advances in Photodynamic Therapy

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Publisher : Artech House
ISBN 13 : 1596932783
Total Pages : 601 pages
Book Rating : 4.5/5 (969 download)

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Book Synopsis Advances in Photodynamic Therapy by : Michael R. Hamblin

Download or read book Advances in Photodynamic Therapy written by Michael R. Hamblin and published by Artech House. This book was released on 2008 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: With today's focus on targeted and minimally invasive therapies, photodynamic therapy (PDT) is now being studied and used to combat many disease states and to investigate critical biological questions. This groundbreaking resource brings you the latest advances in photodynamic therapy and offers you a solid understanding of the design, delivery and dosimetry of the three basic ingredients of PDT - photosensitizers, light and oxygen. The book covers novel areas of mechanistic and innovative translational approaches. Moreover, it gives you an overview of the important medical applications of PDT, including approved treatments, clinical trials, and investigated therapies for cancer and non-malignant diseases.

Handbook of Anticancer Drugs from Marine Origin

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Publisher : Springer
ISBN 13 : 3319071459
Total Pages : 801 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Handbook of Anticancer Drugs from Marine Origin by : Se-Kwon Kim

Download or read book Handbook of Anticancer Drugs from Marine Origin written by Se-Kwon Kim and published by Springer. This book was released on 2014-11-27 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.

Tumor Suppressor Genes in Human Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 1592592309
Total Pages : 441 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Tumor Suppressor Genes in Human Cancer by : David E. Fisher

Download or read book Tumor Suppressor Genes in Human Cancer written by David E. Fisher and published by Springer Science & Business Media. This book was released on 2000-10-26 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: David Fisher, MD, PhD, and an authoritative panel of academic, cutting-edge researchers review and summarize the current state of the field. Describing the broad roles of tumor suppressors from a perspective based in molecular biology and genetics, the authors detail the major suppressors and the pathways they regulate, including cell cycle progression, stress responses, apoptosis, and responses to DNA damage. Leading-edge and forward-looking, Tumor Suppressor Genes in Human Cancer illuminates what is currently known of tumor suppressor genes and their regulation, work that is already beginning to revolutionize cancer target elucidation, drug discovery, and treatment design.

Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

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Publisher : Academic Press
ISBN 13 : 0128127384
Total Pages : 294 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy by :

Download or read book Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy written by and published by Academic Press. This book was released on 2018-11-21 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tyrosine Kinase Inhibitors as Sensitizing Agents for Chemotherapy, the fourth volume in the Cancer Sensitizing Agents for Chemotherapy Series, focuses on strategic combination therapies that involve a variety of tyrosine kinase inhibitors working together to overcome multi-drug resistance in cancer cells. The book discusses several tyrosine kinase inhibitors that have been used as sensitizing agents, such as EGFR, BCR-ABL, ALK and BRAF. In each chapter, readers will find comprehensive knowledge on the inhibitor and its action, including its biochemical, genetic, and molecular mechanisms' emphases. This book is a valuable source for oncologists, cancer researchers and those interested in applying new sensitizing agents to their research in clinical practice and in trials. - Summarizes the sensitizing role of some tyrosine kinase inhibitors in existing research - Brings recent findings in several cancer types, both experimental and clinically, with a particular emphases on underlying biochemical, genetic, and molecular mechanisms - Provides an updated and comprehensive knowledge regarding the field of combinational cancer treatment

PEGylated Protein Drugs: Basic Science and Clinical Applications

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Publisher : Springer Science & Business Media
ISBN 13 : 3764386797
Total Pages : 289 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis PEGylated Protein Drugs: Basic Science and Clinical Applications by : Francesco M. Veronese

Download or read book PEGylated Protein Drugs: Basic Science and Clinical Applications written by Francesco M. Veronese and published by Springer Science & Business Media. This book was released on 2009-12-30 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.

Science of Ashwagandha: Preventive and Therapeutic Potentials

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Publisher : Springer
ISBN 13 : 3319591924
Total Pages : 517 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Science of Ashwagandha: Preventive and Therapeutic Potentials by : Sunil C. Kaul

Download or read book Science of Ashwagandha: Preventive and Therapeutic Potentials written by Sunil C. Kaul and published by Springer. This book was released on 2017-09-13 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapidly increasing aging population and environmental stressors are the two main global concerns of increasing incidence of a variety of pathologies in the modern society. The complex etiologies and pathologies cause major challenges to disease treatment. On the other hand, several herbs are known for their health-caring and disease-curing activities. Ashwagandha, a popular herb in Indian traditional home medicine, Ayurveda, has gathered increasing recognition in recent years when the chemically synthesized drugs for single target therapies showed limited success and adverse toxic effects. Ashwagandha is known as a powerful adaptogen and trusted to enhance function of the brain, reproductive system, cell-mediated immunity and increase the body's defense against disease, and possess anti-inflammatory, anticancer and anti-arthritic activities. In this book, for the first time, we provide a complete portrait on scientific understanding of the effects of Ashwagandha and its active principles for a variety of preventive and therapeutic activities.

Molecular and Cell Biology of Cancer

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Publisher : Springer
ISBN 13 : 3030118126
Total Pages : 216 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Molecular and Cell Biology of Cancer by : Rita Fior

Download or read book Molecular and Cell Biology of Cancer written by Rita Fior and published by Springer. This book was released on 2019-06-27 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg “Hallmarks of Cancer” are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book’s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease

Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease

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Publisher : Springer
ISBN 13 : 1493920537
Total Pages : 452 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease by : Deric L. Wheeler

Download or read book Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease written by Deric L. Wheeler and published by Springer. This book was released on 2014-11-26 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease, for the first time, systematically covers the shared structural and functional features of the RTK family. Receptor Tyrosine Kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases. And over the last decade they have become the Number 1 targets of cancer drugs. To be able to conduct fundamental research or to attempt to develop pharmacological agents able to enhance or intercept them, it is essential first to understand the evolutionary origin of the 58 RTKs and their roles in invertebrates and in humans, as well as downstream signaling pathways. The assembly of chapters is written by experts and underscores commonalities between and among the RTKs. It is an ideal companion volume to The Receptor Tyrosine Kinase: Families and Subfamilies, which proceeds, family by family through all of the specific subfamilies of RTKs, along with their unique landmarks.

Autophagy and Senescence in Cancer Therapy

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Publisher : Academic Press
ISBN 13 : 0128241594
Total Pages : 384 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Autophagy and Senescence in Cancer Therapy by :

Download or read book Autophagy and Senescence in Cancer Therapy written by and published by Academic Press. This book was released on 2021-04-13 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research, Volume 150, the latest release in this ongoing series, covers the relationship(s) between autophagy and senescence, how they are defined, and the influence of these cellular responses on tumor dormancy and disease recurrence. Specific sections in this new release include Autophagy and senescence, converging roles in pathophysiology, Cellular senescence and tumor promotion: role of the unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and senescence for cancer treatment, Autophagy and PTEN in DNA damage-induced senescence, mTOR as a senescence manipulation target: A forked road, and more. Addresses the relationship between autophagy and senescence in cancer therapy Covers autophagy and senescence in tumor dormancy Explores autophagy and senescence in disease recurrence

Cerebral Ischemic Reperfusion Injuries (CIRI)

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Publisher : Springer
ISBN 13 : 331990194X
Total Pages : 269 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Cerebral Ischemic Reperfusion Injuries (CIRI) by : Weijian Jiang

Download or read book Cerebral Ischemic Reperfusion Injuries (CIRI) written by Weijian Jiang and published by Springer. This book was released on 2018-06-29 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is focused on subjects related to cerebral ischemia and reperfusion injuries after acute stroke. All chapters are selected from the Sixth Elite Stroke meeting named Pangu Stroke Conference and written by members of world leading laboratories of stroke studies. The contents cover both clinical and bench studies, from basic components of cerebral arterial system to clinical reperfusion injury cases, from reperfusion caused programmed cell death and astrocyte activation to oxidative stress and nitric oxide after reperfusion, from extracellular matrix and inflammation to a role of diabetes after reperfusion, from small artery disorders to collateral circulation and blood pressure control after reperfusion. Wei-Jian Jiang, Chairman of New Era Stroke Care and Research Institute of PLA Rocket Force General Hospital, Beijing, China. Wengui Yu, Professor and Director of Comprehensive Stroke & Cerebrovascular Center, University of California, Irvine Yan Qu, Professor and Director of Neurosurgery at the Second Affiliated Hospital of Air Force Medical University, Xi’an, China. Zhongsong Shi, Professor of Neurosurgery at Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. Ben-yan Luo, Professor and Chair of Neurology at the First Affiliated Hospital of Zhejiang University. John H. Zhang, Professor of Anesthesiology and Physiology at Loma Linda University School of Medicine, Loma Linda, CA, USA.

Tumor Microenvironment and Cellular Stress

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Publisher : Springer Science & Business Media
ISBN 13 : 146145915X
Total Pages : 293 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Tumor Microenvironment and Cellular Stress by : Constantinos Koumenis

Download or read book Tumor Microenvironment and Cellular Stress written by Constantinos Koumenis and published by Springer Science & Business Media. This book was released on 2013-11-23 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more. Additional topics include identifying common pathways that are potential candidates for therapeutic intervention, which will stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery.

Targeted Therapies for Lung Cancer

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Publisher : Springer
ISBN 13 : 3030178323
Total Pages : 238 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Targeted Therapies for Lung Cancer by : Ravi Salgia

Download or read book Targeted Therapies for Lung Cancer written by Ravi Salgia and published by Springer. This book was released on 2019-06-26 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contextualizes translational research and provides an up to date progress report on therapies that are currently being targeted in lung cancer. It is now well established that there is tremendous heterogeneity among cancer cells both at the inter- and intra-tumoral level. Further, a growing body of work highlights the importance of targeted therapies and personalized medicine in treating cancer patients. In contrast to conventional therapies that are typically administered to the average patient regardless of the patient’s genotype, targeted therapies are tailored to patients with specific traits. Nonetheless, such genetic changes can be disease-specific and/or target specific; thus, the book addresses these issues manifested in the somatically acquired genetic changes of the targeted gene. Each chapter is written by a leading medical oncologist who specializes in thoracic oncology and is devoted to a particular target in a specific indication. Contributors provide an in-depth review of the literature covering the mechanisms underlying signaling, potential cross talk between the target and downstream signaling, and potential emergence of drug resistance.

Development of the Cerebellum from Molecular Aspects to Diseases

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Publisher : Springer
ISBN 13 : 3319597493
Total Pages : 502 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Development of the Cerebellum from Molecular Aspects to Diseases by : Hassan Marzban

Download or read book Development of the Cerebellum from Molecular Aspects to Diseases written by Hassan Marzban and published by Springer. This book was released on 2017-07-27 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors present the most current and cutting-edge knowledge regarding the molecular basis of cerebellar development, focusing on information relevant to laboratory scientists and clinicians providing service to patients with cerebellar disorders. Knowledge obtained from advanced neuroimaging techniques that are used during development, and from molecular- and genetic-based studies has provided rapidly-growing evidence that the cerebellum is a brain region that is highly impacted by developmental defects. Cerebellar defects result in significant intellectual and motor function impairment that affects both the patients and their families.