Immunohistochemical Expression

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Immunohistochemical Expression

Author : Rosario Caltabiano
Publisher : MDPI
ISBN 13 : 3036504001
Total Pages : 168 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Immunohistochemical Expression by : Rosario Caltabiano

Download or read book Immunohistochemical Expression written by Rosario Caltabiano and published by MDPI. This book was released on 2021-09-02 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunohistochemistry (IHC) is an ancillary method, widely used in pathologists’ practice, that allows identifying diagnostic and prognostic/predictive of therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies and chromogenic substances that guarantee the visualization of an antibody–antigene binding complex under a light microscope [1]. Coon et al., in 1941 [2], first introduced the use of fluorochrome-conjugated antibodies in clinical practice. Since then, IHC has gone from being a useful tool for identifying the differentiation line of otherwise undifferentiated cells to a technique capable of providing not only diagnostic but also prognostic and predictive indications of responses to specific therapeutic options [1,3]. The abovementioned peculiarities have made IHC one of the most used ancillary methods in the histopathological approach to human neoplastic and non-neoplastic diseases [3-5]. This Special Issue contains 11 accepted papers that provide readers with a comprehensive update on current and future applications of IHC in medical practice.

Immunohistochemical Expression

Author : Rosario Caltabiano
Publisher :
ISBN 13 : 9783036504018
Total Pages : 168 pages
Book Rating : 4.5/5 (4 download)

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Book Synopsis Immunohistochemical Expression by : Rosario Caltabiano

Download or read book Immunohistochemical Expression written by Rosario Caltabiano and published by . This book was released on 2021 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunohistochemistry (IHC) is an ancillary method, widely used in pathologists' practice, that allows identifying diagnostic and prognostic/predictive of therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies and chromogenic substances that guarantee the visualization of an antibody-antigene binding complex under a light microscope [1]. Coon et al., in 1941 [2], first introduced the use of fluorochrome-conjugated antibodies in clinical practice. Since then, IHC has gone from being a useful tool for identifying the differentiation line of otherwise undifferentiated cells to a technique capable of providing not only diagnostic but also prognostic and predictive indications of responses to specific therapeutic options [1,3]. The abovementioned peculiarities have made IHC one of the most used ancillary methods in the histopathological approach to human neoplastic and non-neoplastic diseases [3-5]. This Special Issue contains 11 accepted papers that provide readers with a comprehensive update on current and future applications of IHC in medical practice.

Immunohistochemistry in Tumor Diagnostics

Author : Muin S.A. Tuffaha
Publisher : Springer
ISBN 13 : 3319535773
Total Pages : 257 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Immunohistochemistry in Tumor Diagnostics by : Muin S.A. Tuffaha

Download or read book Immunohistochemistry in Tumor Diagnostics written by Muin S.A. Tuffaha and published by Springer. This book was released on 2017-09-25 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive yet concise overview of immunoprofile of tumors and antibodies used in contemporary surgical pathology, and provides diagnostic algorithms for approaching tumor diagnostics. Immunohistochemistry has become the most important ancillary technique in diagnostic pathology in the last 20 years, and unlike most books on tumor diagnostics, this volume discusses in details immunohistochemical biomarkers, diagnostic approaches and their pitfalls, as well as the immunoprofile of common tumors throughout all systems of human body. With numerous color figures and detailed flowcharts, it appeals to all pathologists be they young residents in training who want a brief introduction to this technique, or specialists in need of a reliable and comprehensive reference resource in tumors diagnostics.

Handbook of Practical Immunohistochemistry

Author : Fan Lin
Publisher : Springer
ISBN 13 : 1493915789
Total Pages : 756 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Handbook of Practical Immunohistochemistry by : Fan Lin

Download or read book Handbook of Practical Immunohistochemistry written by Fan Lin and published by Springer. This book was released on 2015-02-21 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a conceptually current, quick-reference, Question & Answer format, the second edition of Handbook of Practical Immunohistochemistry: Frequently Asked Questions continues to provide a comprehensive and yet concise state-of-the-art overview of the major issues specific to the field of immunohistochemistry. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 10,000 tumors and normal tissue to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes. Fully revised and updated from the first edition, the new features of the second edition include over 200 additional questions or revised questions with an IHC panel to answer each question; over 250 new color photos and illustrations; over 20 new useful biomarkers; hundreds of new references; several new chapters to cover phosphoproteins, rabbit monoclonal antibodies, multiplex IHC stains, overview of predictive biomarkers, and integration of IHC into molecular pathology; many new coauthors who are international experts in a related field; many updated IHC panels using Geisinger IHC data collected from over 10,000 tumors and normal tissues; and updated appendices containing detailed antibody information for both manual and automated staining procedures. Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, Second Edition will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.

The Immunohistochemical Expression MTA 1 Protein and Its Prognostic Value in Pancreatic Cancer

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (15 download)

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Book Synopsis The Immunohistochemical Expression MTA 1 Protein and Its Prognostic Value in Pancreatic Cancer by :

Download or read book The Immunohistochemical Expression MTA 1 Protein and Its Prognostic Value in Pancreatic Cancer written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Modern Immunohistochemistry

Author : Peiguo Chu
Publisher : Cambridge University Press
ISBN 13 : 1316184455
Total Pages : 1179 pages
Book Rating : 4.3/5 (161 download)

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Book Synopsis Modern Immunohistochemistry by : Peiguo Chu

Download or read book Modern Immunohistochemistry written by Peiguo Chu and published by Cambridge University Press. This book was released on 2014-02-27 with total page 1179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of this best-selling book in 2009, the field of immunohistochemistry has advanced significantly. Fully updated to reflect the latest developments in the field, Modern Immunohistochemistry, Second Edition, is a practical guide to all the important diagnostic markers in each organ system. Concise text is supplemented by over 1,100 high-quality colour images and algorithms. The new edition features even more summary tables, highlighting the key points of differential immunophenotypic panels. A new, expanded introduction explains the basic principles of immunohistochemistry, and chapters have been updated to incorporate predictive/prognostic markers and the latest WHO classifications. All chapters are written by the same expert authors, providing a consistent, engaging style throughout and avoiding contradictory advice. An essential text for residents, this is also an extremely valuable resource for practitioners in anatomic pathology wishing to familiarise themselves with diagnostic markers at a quick glance.

In Situ Molecular Pathology and Co-expression Analyses

Author : Gerard J. Nuovo
Publisher : Academic Press
ISBN 13 : 0128206543
Total Pages : 422 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis In Situ Molecular Pathology and Co-expression Analyses by : Gerard J. Nuovo

Download or read book In Situ Molecular Pathology and Co-expression Analyses written by Gerard J. Nuovo and published by Academic Press. This book was released on 2020-09-03 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major advancements in the field of in situ molecular pathology have occurred since publication of the first edition. In Situ Molecular Pathology and Co-expression Analyses, Second Edition, continues to teach both the molecular basis for the improvements and the actual protocols. This is the unique feature that separates it from the pack of other "cook-book" type approaches. The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods. Further, knowledge of the marked improvements in the reagents themselves since the first edition can make the difference of excellent versus misleading data. The automated platforms require that researchers and diagnostic biomedical investigators have a good understanding of the basics of in situ based tests, protocols, and biochemistry for troubleshooting in order to maximize the use of these platforms. This second edition focuses attention on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. Practicing molecular pathologists, diagnostic pathologists, laboratory directors, and toxicologists, as well as clinicians and researchers in training, will benefit from this clear presentation of protocols and theoretical framework. Data derived from in situ hybridization and immunohistochemistry. - Explains the theory and foundation of immunohistochemistry and in situ hybridization and presents easy-to-follow experimental protocols with tricks of the trade - Includes two new chapters: Recent improvements in immunohistochemistry and in situ hybridization, Quality control for immunohistochemistry and in situ hybridization: How to know if the color change is signal or background - The second edition also includes a detailed test to help one learn the basics of histologic interpretation of tissues and a separate detailed test in how to differentiate signal from background - Includes chapter-ending summaries of Key Points to Remember, bringing beginners up to speed with any seasoned veteran in the field - Thoughtfully tackles the molecular basis if IHC and ISH, along with application of that knowledge to improving the techniques is significant

Biobanking

Author : William H. Yong
Publisher : Humana Press
ISBN 13 : 9781493989331
Total Pages : 470 pages
Book Rating : 4.9/5 (893 download)

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Book Synopsis Biobanking by : William H. Yong

Download or read book Biobanking written by William H. Yong and published by Humana Press. This book was released on 2018-12-14 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume not only discusses various common biobanking topics, it also delves into less-discussed subjects such as what is needed to start a biobank, training of new biobanking personnel, and ethnic representation in biospecimen research. Other chapters in this book span practical topics including: disaster prevention and recovery; information technology; flora and fauna preservation including zoological fluid specimen photography; surgical and autopsy biobanking; biobanking of bodily fluids; biosafety; cutting frozen sections; immunohistochemistry; nucleic acid extraction; and biospecimen shipping. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Unique and comprehensive, Biobanking: Methods and Protocols is a valuable resource for novice and practicing biobankers, and for end-user researchers. This book aims to bring new insight into the field and expand on current biomedical biobanking studies.

Immunohistochemical Expression Study of Pro-apoptotic BH3-only Protein Bad in Canine Non-neoplastic Tissues and Canine Lymphomas

Author : Martina Andrea Dettwiler
Publisher :
ISBN 13 :
Total Pages : 27 pages
Book Rating : 4.:/5 (861 download)

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Book Synopsis Immunohistochemical Expression Study of Pro-apoptotic BH3-only Protein Bad in Canine Non-neoplastic Tissues and Canine Lymphomas by : Martina Andrea Dettwiler

Download or read book Immunohistochemical Expression Study of Pro-apoptotic BH3-only Protein Bad in Canine Non-neoplastic Tissues and Canine Lymphomas written by Martina Andrea Dettwiler and published by . This book was released on 2013 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunohistochemistry in Diagnostic Dermatopathology

Author : Mai P. Hoang
Publisher : Cambridge University Press
ISBN 13 : 1107150167
Total Pages : 315 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Immunohistochemistry in Diagnostic Dermatopathology by : Mai P. Hoang

Download or read book Immunohistochemistry in Diagnostic Dermatopathology written by Mai P. Hoang and published by Cambridge University Press. This book was released on 2017-09-28 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of only a few textbooks on the market dedicated to the important role of immunohistochemistry in diagnostic dermatopathology.

Handbook of Practical Immunohistochemistry

Author : Fan Lin
Publisher : Springer Science & Business Media
ISBN 13 : 1441980628
Total Pages : 616 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Handbook of Practical Immunohistochemistry by : Fan Lin

Download or read book Handbook of Practical Immunohistochemistry written by Fan Lin and published by Springer Science & Business Media. This book was released on 2011-07-01 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a conceptually current, quick-reference, Question & Answer format, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions provides standardization of the immunostaining process for each antibody and for each staining panel. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 5,000 tumors to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes. Chapters are presented in a unique Question and Answer format. One table/IHC panel is provided to address each question. A concise explanatory note follows each table/panel to avoid diagnostic pitfalls. Website links are provided throughout to update the massive information in this field, providing the most current knowledge and the potential for live expert consultation. All chapters are written by nationally/internationally recognized experts in the related area ensuring authority and excellence. Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.

Diagnostic Immunohistochemistry

Author : David J. Dabbs
Publisher :
ISBN 13 :
Total Pages : 690 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Diagnostic Immunohistochemistry by : David J. Dabbs

Download or read book Diagnostic Immunohistochemistry written by David J. Dabbs and published by . This book was released on 2002 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: 17 world-renowned experts offer the most current information and reliable guidance on immunohistochemical diagnoses in surgical pathology and cytopathology. Introductory chapters cover cost modeling for immunohistochemistry and immunohistochemical techniques. The following chapters utilize an organ systems and diseases approach to diagnostic tumor pathology. "A newly updated book that our laboratory staff have found very useful in our day to day work" Reviewed by: PathLab.org, Sept 2014 "...It also acts as an up-to-date bench-top reference tool. It is an easy-to-read, wellpresented text that I would recommend as a 'must have' for every pathology department". Reviewed by: Dr Gemma Petts, Imperial College London on behalf of The Bulletin of The Royal College of Pathologists, Oct 2014 Consistently organized chapters for quick access to vital information Each chapter "stands alone," providing all the information you might need on a specific topic Quick-reference boxes summarize the most important diagnostic points at the end of each text Section Colour photographs and illustrations reinforce key diagnostic points

Antigen Retrieval Techniques

Author : Shan-Rong Shi
Publisher : Eaton Publishing Company/Biotechniques Books
ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Antigen Retrieval Techniques by : Shan-Rong Shi

Download or read book Antigen Retrieval Techniques written by Shan-Rong Shi and published by Eaton Publishing Company/Biotechniques Books. This book was released on 2000 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Flow Cytometry, Immunohistochemistry, and Molecular Genetics for Hematologic Neoplasms

Author : Tsieh Sun
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451180640
Total Pages : 449 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Flow Cytometry, Immunohistochemistry, and Molecular Genetics for Hematologic Neoplasms by : Tsieh Sun

Download or read book Flow Cytometry, Immunohistochemistry, and Molecular Genetics for Hematologic Neoplasms written by Tsieh Sun and published by Lippincott Williams & Wilkins. This book was released on 2012-01-19 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunophenotyping is the most powerful tool in the routine diagnosis of hematologic neoplasms. Immunohistochemical technique is used in histology labs for this purpose, while flow cytometry is used in clinical labs. Although separately these 2 techniques are very useful in detecting lymphomas and leukemias, the combination of both creates a very powerful and definitive diagnostic tool. The addition of molecular genetics to the book makes it an all-encompassing reference text.

Diagnostic Immunohistochemistry E-Book

Author : David J Dabbs
Publisher : Elsevier Health Sciences
ISBN 13 : 0323225098
Total Pages : 1157 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Diagnostic Immunohistochemistry E-Book by : David J Dabbs

Download or read book Diagnostic Immunohistochemistry E-Book written by David J Dabbs and published by Elsevier Health Sciences. This book was released on 2013-10-11 with total page 1157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Immunohistochemistry presents the latest information and most reliable guidance on immunohistological diagnoses in surgical pathology. David J. Dabbs, MD and other leading experts bring you state-of-the-art coverage on genomic and theranostic applications, molecular anatomic pathology, immunocytology, Non-Hodgkin’s lymphoma, and more. Additional features such as tables discussing antibody specifications, differential diagnosis boxes, ancillary anatomic molecular diagnostics, and full-color histological images ensure user-friendly coverage that makes key information easy to find and apply. This concise and complete resource is today’s indispensable guide to the effective use of immunohistochemical diagnosis. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Presents chapters arranged by organ system for comprehensive coverage of all relevant information in a convenient and intuitive organization. Provides quick reference graphs for antibodies throughout the text that illustrate the frequency of immunostaining for a variety of antibodies in tumors. Includes Key Diagnostic Points boxes in every chapter for a quick summary of text areas that are of particular importance. Features an expert author for each chapter to ensure coverage of the current state of the art.

Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas

Author : M. A. Hayat
Publisher : Elsevier
ISBN 13 : 0080457878
Total Pages : 609 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas by : M. A. Hayat

Download or read book Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas written by M. A. Hayat and published by Elsevier. This book was released on 2006-05-23 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: Classical histology has been augmented by immunohistochemistry (the use of specific antibodies to stain particular molecular species in situ). Immunohistochemistry has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method.* The only book available that translates molecular genetics into cancer diagnosis * Methods were developed by internationally-recognized experts and presented in step-by-step manner * Results of each Immunohistochemical and in situ hybridization are presented in the form of color illustrations

Modern Surgical Pathology E-Book

Author : Noel Weidner
Publisher : Elsevier Health Sciences
ISBN 13 : 1437719589
Total Pages : 1294 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Modern Surgical Pathology E-Book by : Noel Weidner

Download or read book Modern Surgical Pathology E-Book written by Noel Weidner and published by Elsevier Health Sciences. This book was released on 2009-07-08 with total page 1294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Surgical Pathology, 2nd Edition presents today's most complete, current, and practical assistance in evaluating and signing out surgical specimens. Nearly 3,000 high-quality color pathology images provide a crystal-clear basis for comparison to any sample you see under the microscope. Clinical, gross, microscopic, immunohistochemical, and molecular genetic features are integrated as appropriate for all tumors and tumor-like lesions, addressing all of the investigative contexts relevant to formulating an accurate diagnosis. Edited by four leading surgical pathologists - Noel Weidner, MD, Richard J. Cote, MD, Saul Suster, MD and Lawrence M. Weiss, MD - with contributions from more than 70 other experts, Modern Surgical Pathology, 2nd Edition delivers the well-rounded, well-organized, richly illustrated, user-friendly guidance you need to efficiently arrive at confident diagnoses for even the most challenging lesions. Contributions from many leading surgical pathologists give you well-rounded, expert answers to any question that you may face. Clinical, gross, microscopic, immunohistochemical, and molecular genetic features are correlated as appropriate for every type of surgical pathology specimen, addressing all of the investigative contexts relevant to formulating an accurate diagnosis and thereby ensuring a completely accurate surgical report. Nearly 3,000 brand-new, high-quality color pathology images provide a crystal-clear basis for comparison to any specimen you see under the microscope. A completely rewritten section on the female reproductive tract offers many more illustrations of common entities to help you more easily distinguish between tumors and tumor-like lesions. Expanded coverage of non-neoplastic diseases and disorders makes it easier to recognize benign conditions that can mimic malignancy. The latest classification schemes and criteria for malignancy, incorporated throughout, enable you to include the most current gradings in your reports. A new, more consistent organization explores anatomy/histology, gross and microscopic appearance, adjunct techniques, diagnosis, and differential diagnosis for each neoplastic or non-neoplastic lesion, facilitating rapid consultation in the reporting room. An increased number of differential diagnosis and classification tables expedite diagnosis.