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Host Response To Biomaterials
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Book Synopsis Host Response to Biomaterials by : Stephen F Badylak
Download or read book Host Response to Biomaterials written by Stephen F Badylak and published by Academic Press. This book was released on 2015-05-08 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response. The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the transition from simple to complex biomaterial solutions. Fields covered include, but are not limited to, orthopaedic surgery, dentistry, general surgery, neurosurgery, urology, and regenerative medicine. Explains the various categories of biomaterials and their significance for clinical applications Contains a range of extensive coverage, including, but not limited to, orthopedic, surgery, dental, general surgery, neurosurgery, lower urinary tract, and regenerative medicine Includes regulations regarding combination devices
Download or read book Biosurfaces written by Kantesh Balani and published by John Wiley & Sons. This book was released on 2015-01-23 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideal as a graduate textbook, this title is aimed at helpingdesign effective biomaterials, taking into account the complexinteractions that occur at the interface when a synthetic materialis inserted into a living system. Surface reactivity,biochemistry, substrates, cleaning, preparation, and coatingsare presented, with numerous case studies and applicationsthroughout. Highlights include: Starts with concepts and works up to real-life applicationssuch as implantable devices, medical devices, prosthetics, and drugdelivery technology Addresses surface reactivity, requirements for surface coating,cleaning and preparation techniques, and characterization Discusses the biological response to coatings Addresses biomaterial-tissue interaction Incorporates nanomechanical properties and processingstrategies
Book Synopsis Immunomodulatory Biomaterials by : Stephen F. Badylak
Download or read book Immunomodulatory Biomaterials written by Stephen F. Badylak and published by Woodhead Publishing. This book was released on 2021-07-30 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an “inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response Provides a single reference for understanding and utilizing the host response in biomaterials design An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area
Book Synopsis The Immune Response to Implanted Materials and Devices by : Bruna Corradetti
Download or read book The Immune Response to Implanted Materials and Devices written by Bruna Corradetti and published by Springer. This book was released on 2016-11-30 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.
Book Synopsis Biomaterials and Immune Response by : Nihal Engin Vrana
Download or read book Biomaterials and Immune Response written by Nihal Engin Vrana and published by CRC Press. This book was released on 2018-07-20 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted materials as a failure of immune system/biomaterial interactions; iv) tissue-specific effects of immune response and its consequences for tissue engineering and regenerative medicine; v) immune reaction in a clinical context (periodontology). In the field of biomaterials there are significant advances in using immunomodulation techniques to improve the success rates of implantable materials. For better understanding of such techniques it is required to have a full grasp of the biomaterial–immune system interactions. This would greatly enhance the understanding of why the human body reacts to implants in a certain way and how to improve the clinical outcomes by developing immune-instructive biomaterials. Provides keen insight into biomaterial–immune cell interactions Presents an explanation of state-of-the-art methodologies in immunomodulation Offers a concise and simple-to-understand treatment of biomaterial–immune cell interactions for materials scientists in a biology heavy topic Explores a comprehensive overview of biomaterial related complications Provides extensive references at the end of each chapter to enhance study for this very hot research area
Book Synopsis Biomaterials in Regenerative Medicine and the Immune System by : Laura Santambrogio
Download or read book Biomaterials in Regenerative Medicine and the Immune System written by Laura Santambrogio and published by Springer. This book was released on 2015-09-04 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as those employed in orthopedic surgery or vascular stents, can often induce an immune reaction to their basic components. As a result, this book is also an important step towards coming to understand how to manipulate biomaterials to optimize their beneficial effects and downplay detrimental immune responses.
Book Synopsis Regenerative Medicine Applications in Organ Transplantation by : Giuseppe Orlando
Download or read book Regenerative Medicine Applications in Organ Transplantation written by Giuseppe Orlando and published by Academic Press. This book was released on 2013-10-11 with total page 1050 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration Explains the importance and future potential of regenerative medicine to the transplant community Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions
Book Synopsis In Situ Tissue Regeneration by : Sang Jin Lee
Download or read book In Situ Tissue Regeneration written by Sang Jin Lee and published by Academic Press. This book was released on 2016-07-17 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body’s ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body’s own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications. Explores the body’s ability to mobilize endogenous stem cells to the site of injury Details the latest strategies developed for inducing and supporting the body’s own regenerating capacity Presents smart biomaterials in cell-based tissue engineering applications—from the cell level to applications—in the first unified volume Features chapter authors and editors who are authorities in this emerging field Prioritizes a discussion of the future direction of smart biomaterials for in situ tissue regeneration, which will affect an emerging and lucrative industry
Book Synopsis Biomaterials from Nature for Advanced Devices and Therapies by : Nuno M. Neves
Download or read book Biomaterials from Nature for Advanced Devices and Therapies written by Nuno M. Neves and published by John Wiley & Sons. This book was released on 2016-10-24 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: In-depth information on natural biomaterials and their applications for translational medicine! Undiluted expertise: edited by world-leading experts with contributions from top-notch international scientists, collating experience and cutting-edge knowledge on natural biomaterials from all over the world A must-have on the shelf in every biomaterials lab: graduate and PhD students beginning their career in biomaterials science and experienced researchers and practitioners alike will turn to this comprehensive reference in their daily work Link to clinical practice: chapters on translational research make readers aware of what needs to be considered when a biomaterial leaves the lab to be routinely used
Book Synopsis Biomaterials by : Véronique Migonney
Download or read book Biomaterials written by Véronique Migonney and published by John Wiley & Sons. This book was released on 2014-10-13 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discovered in the 20th century, biomaterials have contributed to many of the incredible scientific and technological advancements made in recent decades. This book introduces and details the tenets of biomaterials, their relevance in a various fields, practical applications of their products, and potential advancements of the years to come. A comprehensive resource, the text covers the reasons that certain properties of biomaterials contribute to specific applications, and students and researchers will appreciate this exhaustive textbook.
Book Synopsis Biomaterials Associated Infection by : Fintan Moriarty
Download or read book Biomaterials Associated Infection written by Fintan Moriarty and published by Springer Science & Business Media. This book was released on 2012-09-29 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials associated infection (BAI) is one of the most common complications associated with implantation of any biomaterial regardless of form or function. These infections usually involve bacterial colonization and biofilm formation on the biomaterial itself, rendering the infection impervious to antimicrobials and host defenses. In addition, it is becoming increasingly clear that infection of the surrounding tissues also plays an important role in BAI, and that the infection may be influenced by the composition and design of the implanted biomaterial. In this book, worldwide leaders in the field address this critical problem in the translation of biomaterials research into clinical practice. The book begins with an emphasis on the latest research in the pathogenesis of BAI from microbiological, immunological, and materials science perspectives. The current state of the art in antimicrobial activation of biomaterials through surface modification and the incorporation of antimicrobial agents is then discussed. In the concluding chapters, successful translation of a selection of antimicrobial technologies from preclinical research into clinical use is described alongside a discussion of the utility of these devices and perspectives for future development. This book is essential reading for researchers and clinicians who are interested in understanding the fundamentals of BAI, the latest in antimicrobial materials research, and the state of the art in clinically available antimicrobial containing medical devices.
Book Synopsis Bone Augmentation by Anatomical Region by : Zvi Artzi
Download or read book Bone Augmentation by Anatomical Region written by Zvi Artzi and published by John Wiley & Sons. This book was released on 2020-05-15 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensively describes bone augmentation techniques and their application to the different anatomical regions of the upper and lower jaws. Bone Augmentation by Anatomical Region is a unique, evidence-based guide focusing on each specific anatomical region – anterior maxilla, posterior maxilla, anterior mandible, and posterior mandible – in order to emphasize the correct implemented procedures needed to successfully perform oral osseous reconstruction. Numerous ridge augmentation techniques are covered, including: horizontal and vertical guided bone regeneration, autologous block transplantation, interpositional bone grafting, allogeneic blocks, sandwich technique, split-expansion ridge technique, and sinus floor grafting. Non-augmented approaches such as forced socket site extrusion and the installation of digitally printed implants are also presented and discussed. Guides readers on tackling bone augmentation via anatomical region of the jaws and their related surrounding muscles, vascularization and innervation Presents innovative augmentation techniques for the anterior maxilla, posterior maxilla, anterior mandible, and posterior mandible Includes clinical photographs in each section and a decision tree to help readers select the appropriate surgical modality Bone Augmentation by Anatomical Region is a specialist resource suitable for dentists who practice implant dentistry, oral surgeons, oral and maxillofacial surgeons, periodontists, and postgraduate dental students in the above-mentioned disciplines. Please note Due to recently developments, part of Chapter 2 Biologic Conditions for Bone Growth and Maintenance: Managing the Oxidative Stress has been amended which will be available in all future reprints. All electronic versions have been updated.
Book Synopsis Handbook of Biomaterial Properties by : William Murphy
Download or read book Handbook of Biomaterial Properties written by William Murphy and published by Springer. This book was released on 2016-06-11 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides tabular and text data relating to normal and diseased tissue materials and materials used in medical devices. Comprehensive and practical for students, researchers, engineers, and practicing physicians who use implants, this book considers the materials aspects of both implantable materials and natural tissues and fluids. Examples of materials and topics covered include titanium, elastomers, degradable biomaterials, composites, scaffold materials for tissue engineering, dental implants, sterilization effects on material properties, metallic alloys, and much more. Each chapter author considers the intrinsic and interactive properties of biomaterials, as well as their appropriate applications and historical contexts. Now in an updated second edition, this book also contains two new chapters on the cornea and on vocal folds, as well as updated insights, data, and citations for several chapters.
Book Synopsis Biological Performance of Materials by : Jonathan Black
Download or read book Biological Performance of Materials written by Jonathan Black and published by Marcel Dekker. This book was released on 1992 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Intrinsically Biocompatible Polymer Systems by : Marek Kowalczuk
Download or read book Intrinsically Biocompatible Polymer Systems written by Marek Kowalczuk and published by MDPI. This book was released on 2020-03-25 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biocompatibility refers to the ability of a biomaterial to perform its desired function with respect to a medical therapy, without eliciting any undesirable local or systemic effects in the recipient or beneficiary of that therapy, but generating the most appropriate beneficial cellular or tissue response in that specific situation, and optimizing the clinically relevant performance of that therapy, which reflects current developments in the area of intrinsically biocompatible polymer systems. Polymeric biomaterials are presently used as, for example, long-term implantable medical devices, degradable implantable systems, transient invasive intravascular devices, and, recently, as tissue engineering scaffolds. This Special Issue welcomes full papers and short communications highlighting the aspects of the current trends in the area of intrinsically biocompatible polymer systems.
Book Synopsis Biologically-responsive Hybrid Biomaterials by : Esmaiel Jabbari
Download or read book Biologically-responsive Hybrid Biomaterials written by Esmaiel Jabbari and published by World Scientific. This book was released on 2010 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: conjugate biomaterials have profoundly impacted the medical field. --
Book Synopsis An Introduction to Biomaterials by : Jeffrey O. Hollinger
Download or read book An Introduction to Biomaterials written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2005-12-21 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complexity of biological systems and the need to design and develop biomedical therapies poses major challenges to professionals in the biomedical disciplines. An Introduction to Biomaterials emphasizes applications of biomaterials for patient care. Containing chapters prepared by leading authorities on key biomaterial types, this book underscores the process of biomaterial design, development directed toward clinical application, and testing that leads to therapies for clinical targets. The authors provide a lucid perspective on the standards available and the logic behind the standards in which biomaterials address clinical needs. This volume includes chapters on consensus standards and regulatory approaches to testing paradigms, followed by an analysis of specific classes of biomaterials. The book closes with sections on clinical topics that integrate materials sciences and patient applications.
