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Hormonally Defined Media
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Book Synopsis Hormonally Defined Media by : G. Fischer
Download or read book Hormonally Defined Media written by G. Fischer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until some years ago serum or crude tissue extracts were used pre dominantly or exclusively as media supplements for the cultivation of cells. However, during this time evidence accumulated that these sup plements could not provide in an optimal way most of the cultivated cells with all factors necessary for their survival, their prolifer ation and/or differentiation. Moreover, a variety of cells could not be cultivated at all under these conditions and often the composition of the cultures changed within rather short periods of time by overgrowth of initially present subpopulations of those cells which grow well in these supplements, as for example fibroblasts. Nevertheless, using these supplements (or fractions thereof), insight could be gained into some of the influences of serum or tissue extract constituents with re gard to survival, proliferation and differentiation of cells in cul ture. It became obvious from these experiments that serum or tissue extracts did not only supply cells with nutrients or vitamins (which are now constituents of all basic media), but also with hormones as well as growth-, differentiation-, and attachment-factors. In course of time experiments were performed in which serum enriched with hormones and other growth factors was used to successfully culti vate those cells which could not survive in serum-supplemented media alone. Under normal conditions in an organism, however, only a small population of cells has direct contact with serum.
Book Synopsis Hormonally Active Agents in the Environment by : National Research Council
Download or read book Hormonally Active Agents in the Environment written by National Research Council and published by National Academies Press. This book was released on 2000-02-03 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.
Author :Jens O. L. Jørgensen Publisher :Karger Medical and Scientific Publishers ISBN 13 :3805579926 Total Pages :241 pages Book Rating :4.8/5 (55 download)
Book Synopsis Growth Hormone Deficiency in Adults by : Jens O. L. Jørgensen
Download or read book Growth Hormone Deficiency in Adults written by Jens O. L. Jørgensen and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been known for over 40 years that GH-deficient-children benefit from replacement with the hormone. But GH, essential for longitudinal growth, also plays a role after completion of final height. With the introduction of biosynthetic human GH 20 years ago, the use of GH was no longer restricted to severe growth retardation in hypopituitary children. This book will take the reader behind the myths of GH and into the real world of clinical endocrinology. The contributions stem from recognized clinicians and scientists who have been working in the field for decades. The contents encompass traditional end points of GH therapy such as body composition, bone biology and physical performance. Attention is also devoted to diagnostic aspects and side effects. Additional features range from clinical epidemiology to quality of life, and novel areas such as the impact of traumatic brain injury on pituitary function are also covered. The present volume of Frontiers of Hormone Research is essential reading for health care professionals interested in clinical endocrinology and GH.
Book Synopsis Growth of Cells in Hormonally Defined Media by : David Andrew Sirbasku
Download or read book Growth of Cells in Hormonally Defined Media written by David Andrew Sirbasku and published by . This book was released on 1982 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Growth of Cells in Hormonally Defined Media by : Gordon Sato
Download or read book Growth of Cells in Hormonally Defined Media written by Gordon Sato and published by . This book was released on 1982 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Hormonal Regulation of Mammary Tumors by : Benjamin S. Leung
Download or read book Hormonal Regulation of Mammary Tumors written by Benjamin S. Leung and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept that hormones influence tumor growth originated in 1889 with the proposal of Albert Schinzinger who suggested that breast cancer is related to the ovaries. Several years later, Sir George Beatson observed that remission of disseminated breast cancer could be achieved in premenopausal patients by performing bilateral oophorectomy. As a result of the contri butions of Hedley Atkins, Charles Huggins and others, additive and ablative hormonal therapies have been widely used for the treatment of advanced breast cancers for several decades. Model systems to study the effects of hormones on growth and regression of breast tumors have been available for many years; however, the complexities of the hormonal environment have rendered in vivo studies difficult in man and experimental animals. Recently, the availability of long-term cultures of breast cancer cells has stimulated many investigators to use these cell lines to unravel the mechanisms of hormone action. Because of the extreme diversity and complexity of advances regarding the endocrinology of the breast and breast cancers, a multi-authored review was deemed necessary. It has been gratifying to receive contributions from many noted scholars. In Volume I of this monograph, the influence of steroid hormones and their antagonists upon normal and neoplastic tissues of the mammary gland are presented. In Volume II, the effects of peptide and other hormones are reviewed.
Book Synopsis Introduction to Cell and Tissue Culture by : Jennie P. Mather
Download or read book Introduction to Cell and Tissue Culture written by Jennie P. Mather and published by Springer Science & Business Media. This book was released on 2007-08-20 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a pleasure to contribute the foreword to Introduction to Cell and Tissue Culture: The ory and Techniques by Mather and Roberts. Despite the occasional appearance of thought ful works devoted to elementary or advanced cell culture methodology, a place remains for a comprehensive and definitive volume that can be used to advantage by both the novice and the expert in the field. In this book, Mather and Roberts present the relevant method ology within a conceptual framework of cell biology, genetics, nutrition, endocrinology, and physiology that renders technical cell culture information in a comprehensive, logical for mat. This allows topics to be presented with an emphasis on troubleshooting problems from a basis of understanding the underlying theory. The material is presented in a way that is adaptable to student use in formal courses; it also should be functional when used on a daily basis by professional cell culturists in a- demia and industry. The volume includes references to relevant Internet sites and other use ful sources of information. In addition to the fundamentals, attention is also given to mod ern applications and approaches to cell culture derivation, medium formulation, culture scale-up, and biotechnology, presented by scientists who are pioneers in these areas. With this volume, it should be possible to establish and maintain a cell culture laboratory devot ed to any of the many disciplines to which cell culture methodology is applicable.
Book Synopsis Cell Separation by : Thomas G. Pretlow
Download or read book Cell Separation written by Thomas G. Pretlow and published by Academic Press. This book was released on 2014-05-10 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Separation: Methods and Selected Application, Volume 3 provides information pertinent to the design and application of methods for the separation of cells. This book covers a variety of topics, including lymphoma cells, lectins, purification of cells from lung tumors, macrophage electrophoretic migration test, tissue heterogeneity, and characteristics of cultured cells. Organized into 13 chapters, this volume begins with an overview of the approaches in examining particular cell-surface properties and their role in the metastatic process. This text then examines lectins as important tools for identification and separation of cells, particularly of lymphocyte subpopulations. Other chapters consider the various methods that have been used to disperse rat pituitary tissue into single cells. This book discusses as well the different methods for isolating type II cells. The final chapter deals with the significance of having cell cultures homogeneous for a given cell type. This book is a valuable resource for cell biologists, experimental oncologists, hematologists, immunologists, and endocrinologists.
Book Synopsis Animal Cell Culture and Production of Biologicals by : Ryuzo Sasaki
Download or read book Animal Cell Culture and Production of Biologicals written by Ryuzo Sasaki and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades, the importance of animal cell technology has increased enormously. First, useful proteins can be produced by cultured animal cells, in which the desired product can be modified and organized so as to retain its biological function. Second, studies of cultured cells can provide information needed to understand molecular mechanisms that govern what happens in tissues, organs, and even entire organisms. For this second purpose, biochemists and molecular biologists may need a large number of such cells. Third, cultured cells can be used instead of tissues and organs clinically. The Third Annual Meeting of the Japanese Association for Animal Cell Technology (JAACT), at which participants from abroad were warmly welcomed, was held in Kyoto on December 11-13, 1990. It was organized around the idea of providing a place for the review of much new data on such applications of cultured cells and for exchanges of the views of the participants about progress in the field. This volume, divided into seven sections, contains the proceedings of the meeting. The first section reviews the molecular basis of the control of animal cell growth. In the following sections, physicochemical and biochemical factors for cell growth and production of biologicals, cell culture systems including serum-free culture, new cell lines, specific products and their characteristics, and in vitro assays for toxic, carcinogenic, and pharmacological effects are taken up in their tum.
Book Synopsis Large-Scale Mammalian Cell Culture Technology by : Lubiniecki
Download or read book Large-Scale Mammalian Cell Culture Technology written by Lubiniecki and published by Routledge. This book was released on 2018-05-02 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: An interdisciplinary approach, integrating biochemistry, biology, genetics, and engineering for the effective production of protein pharmaceuticals. The volume offers a biological perspective of large-scale animal cell culture and examines diverse processing strategies, process management, regulator
Book Synopsis Cell Culture in the Neurosciences by : Jane Bottenstein
Download or read book Cell Culture in the Neurosciences written by Jane Bottenstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fundamental problem in neuroscience is the elucidation of the cellular and molecular mechanisms underlying the development and function of the nervous system. The complexity of organization, the heteroge neity of cell types and their interactions, and the difficulty of controlling experimental variables in intact organisms make this a formidable task. Because of the ability that it affords to analyze smaller components of the nervous system (even single cells in some cases) and to better control experimental variables, cell culture has become an increasingly valuable tool for neuroscientists. Many aspects of neural development, such as proliferation, differentiation, synaptogenesis, and myelination, occur in culture with time courses remarkably similar to those in vivo. Thus, in vitro methods often provide excellent model systems for investigating neurobiological questions. Ross Harrison described the first culture of neural tissue in 1907 and used morphological methods to analyze the cultures. Since that time the technique has been progressively modified and used to address an ever widening range of developmental questions. In recent years a con vergence of new or improved cell culture, biochemical, electrophysiol ogical, and immunological methods has occurred and been brought to bear on neurobiological questions. This volume is intended not to be comprehensive but rather to highlight some of the latest findings, with a review of previous important work as well, in which combinations of these methods are used.
Book Synopsis Principles of Toxicology by : Stephen M. Roberts
Download or read book Principles of Toxicology written by Stephen M. Roberts and published by John Wiley & Sons. This book was released on 2014-12-08 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and expanded edition of the bestselling guide on toxicology and its practical application • Covers the diverse chemical hazards encountered in the modern work and natural environment, and provides a practical understanding of these hazards • New chapters cover the emerging areas of toxicology such as omics, computational toxicology, and nanotoxicology • Provides clear explanations and practical understanding of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems • Includes case histories and examples from industry demonstrate the application of toxicological principles • Supplemented with numerous illustrations to clarify and summarize key points, annotated bibliographies, and a comprehensive glossary of toxicological terms
Book Synopsis Hormonal Steroids by : V. H. T. James
Download or read book Hormonal Steroids written by V. H. T. James and published by Elsevier. This book was released on 2013-10-22 with total page 1073 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormonal Steroids presents the proceedings of the Sixth International Congress on Hormonal Steroids, held in Jerusalem, Israel in September 1982. The book covers a wide range of topics on the field of hormonal steroids research. The topics discussed include the history of steroid-protein interaction; enzyme induction by estrogen; steroids and the immune system; correlative morphological and biochemical investigations on the stromal tissue of the human prostate; analysis of intact steroid conjugates by secondary ion mass spectrometry (including fabms) and by gas chromatography; and the role of lipoproteins in steroidogenesis by human luteinized granulosa cells in culture. Biochemists, pathologists, pharmacologists, and medical and pharmaceutical researchers will find the book a good source of insight.
Book Synopsis Methods for Serum-free Culture of Epithelial and Fibroblastic Cells by : David William Barnes
Download or read book Methods for Serum-free Culture of Epithelial and Fibroblastic Cells written by David William Barnes and published by . This book was released on 1984 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Band 3.
Author :Etienne-Emile Baulieu (ed) Publisher :Springer Science & Business Media ISBN 13 :9780412027918 Total Pages :610 pages Book Rating :4.0/5 (279 download)
Book Synopsis Hormones by : Etienne-Emile Baulieu (ed)
Download or read book Hormones written by Etienne-Emile Baulieu (ed) and published by Springer Science & Business Media. This book was released on 1990-11-30 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrinology is a field in which enormous advances have been made in the last decade; the rate of discovery of new hormones, hormone-like molecules, receptors, and mechanisms of action is continually advancing. The development of techniques in immunology and molecular biology has led to the possibility of describing in detail the gene structure of many of the compounds involved in hormonal systems. Remarkable homology has been shown between oncogene products and various components of the endocrine network, leading to the asser tion that deregulation of hormonal function is involved in the generation and/or development of cancer. We now know that the central nervous system is both a target and a production site of many hormonal products, and that hormones, neurotransmitters, growth factors and immunopeptides all act through similar mechanisms. The only second messenger known ten years ago was cAMP; today calcium, derivatives of membrane phospholipids, and protein kinases are also known to be mediators of hormone action. The very concept of hormonal systems has been expanded to include not only endocrine secretions but also para- and autohormones and their mechanisms of action; an understanding of their functions will be central to the immediate future of medicine. The discovery of hormonal molecules and endocrine interactions and the subsequent understanding of hormone related pathophysiology has led to the development of new strategies in medical treatment such as fertility control and the management of diabetes.
Book Synopsis Hormonal Regulation of Plant Growth and Development by : S.S. Purohit
Download or read book Hormonal Regulation of Plant Growth and Development written by S.S. Purohit and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dynamic role of plant hormones in regulation of plant growth and development revealed by its control of rates of metabolic processes and various related enzymetic reactions at molecular and submolecular levels is now weil established. During the course of last 35 years endless development in agricultural biotechnology has provided immense literature to understand hormone-regulated aspects of plant growth and development ; but plant physiologists all over the world are still devoting themselves and will continue for an indifinite period to disclose the mystries of this regulation. Volume I of this series has already been published and has been accepted weil. This encouraged me to edit aseries of volumes (I do not know the number) on this subject. In the following pages various aspects of hormone-controlled physiological processes Iike, Hormonal Control of pro tein synthesis in plants, Auxin-induced elongation, Hormonal regulation of abnormal growth in plants, Hormonal regulation of development in mosses, Some phenolics as plant growth and morphogenesis regulators, Plant growth regulating properties of sterol inhibiting fungicides, Hormonal regulation of sex expression in plants, Water relation and plant growth regulators, Hormonal regulation of root development under water stress, Gravity perception and responses meehanism in graviresponding cereal grass shoots, Hormonal regulation of leaf Growth senescence in relation to stomatal movement, and Chloroindole auxins of pea and related species, have been included.
Book Synopsis Single-Cell-Based Models in Biology and Medicine by : Alexander Anderson
Download or read book Single-Cell-Based Models in Biology and Medicine written by Alexander Anderson and published by Springer Science & Business Media. This book was released on 2007-08-08 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at postgraduate students in a variety of biology-related disciplines, this volume presents a collection of mathematical and computational single-cell-based models and their application. The main sections cover four general model groupings: hybrid cellular automata, cellular potts, lattice-free cells, and viscoelastic cells. Each section is introduced by a discussion of the applicability of the particular modelling approach and its advantages and disadvantages, which will make the book suitable for students starting research in mathematical biology as well as scientists modelling multicellular processes.
