Concepts and Principles of Pharmacology

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Author :
Publisher : Springer Nature
ISBN 13 : 3030353621
Total Pages : 457 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Concepts and Principles of Pharmacology by : James E. Barrett

Download or read book Concepts and Principles of Pharmacology written by James E. Barrett and published by Springer Nature. This book was released on 2019-12-24 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

Gastrointestinal Pharmacology

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Author :
Publisher : Springer
ISBN 13 : 3319563602
Total Pages : 446 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Gastrointestinal Pharmacology by : Beverley Greenwood-Van Meerveld

Download or read book Gastrointestinal Pharmacology written by Beverley Greenwood-Van Meerveld and published by Springer. This book was released on 2017-04-19 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.

Methylxanthines

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Publisher : Springer Science & Business Media
ISBN 13 : 3642134432
Total Pages : 566 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Methylxanthines by : Bertil B. Fredholm

Download or read book Methylxanthines written by Bertil B. Fredholm and published by Springer Science & Business Media. This book was released on 2010-09-22 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the present volume of the Handbook of Experimental Pharmacology well known experts describe the actions of different xanthines with a focus on caffeine and theophylline. A special chapter is devoted to theobromine, an active component of chocolate, the actions of which are less well characterized. This book also presents the pharmacology of one xanthine derivative, propentofylline, as an example of a xanthine that has gone through extensive development for a novel therapeutic area.

Good Research Practice in Non-Clinical Pharmacology and Biomedicine

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Author :
Publisher : Springer Nature
ISBN 13 : 3030336565
Total Pages : 424 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Good Research Practice in Non-Clinical Pharmacology and Biomedicine by : Anton Bespalov

Download or read book Good Research Practice in Non-Clinical Pharmacology and Biomedicine written by Anton Bespalov and published by Springer Nature. This book was released on 2020-01-01 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

Drug Delivery

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118833368
Total Pages : 740 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Drug Delivery by : Binghe Wang

Download or read book Drug Delivery written by Binghe Wang and published by John Wiley & Sons. This book was released on 2016-04-18 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery

Cannabinoids

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540225652
Total Pages : 790 pages
Book Rating : 4.2/5 (256 download)

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Book Synopsis Cannabinoids by : Roger G. Pertwee

Download or read book Cannabinoids written by Roger G. Pertwee and published by Springer Science & Business Media. This book was released on 2005-03-21 with total page 790 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book is an outstanding summary of many aspects of cannabinoid research. It provides current knowledge about the pharmacology and therapeutic potential of cannabinoids as well as knowledge about the pharmacology, physiology, and pathology of the endogenous cannabinoid systems. The chapters are written by scientists who have made or are still making major contributions to the field. This book may well help generate novel ideas on how to approach the study of emotions.

Muscarinic Receptors

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Publisher : Springer Science & Business Media
ISBN 13 : 3642232744
Total Pages : 501 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Muscarinic Receptors by : Allison D. Fryer

Download or read book Muscarinic Receptors written by Allison D. Fryer and published by Springer Science & Business Media. This book was released on 2012-01-06 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muscarinic acetylcholine receptors have played a key role in the advancement of knowledge of pharmacology and neurotransmission since the inception of studies in these fields, and the effects of naturally occurring drugs acting on muscarinic receptors were known and exploited for both therapeutic and non-therapeutic purposes for hundreds of years before the existence of the receptors themselves was recognized. This volume presents a broad yet detailed review of current knowledge of muscarinic receptors that will be valuable both to long-time muscarinic investigators and to those new to the field. It describes the detailed insights that have been obtained on the structure, function, and cell biology of muscarinic receptors. This volume also describes physiological analyses of muscarinic receptors and their roles in regulating the function of the brain and of a variety of peripheral tissues. This volume shows how the study of muscarinic receptors continues to provide new and surprising insights not just to the cholinergic system but to the broad areas of neurobiology, cell biology, pharmacology, and therapeutics.

Pediatric Clinical Pharmacology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642201954
Total Pages : 385 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Pediatric Clinical Pharmacology by : Hannsjörg W. Seyberth

Download or read book Pediatric Clinical Pharmacology written by Hannsjörg W. Seyberth and published by Springer Science & Business Media. This book was released on 2011-09-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this volume is to give an overview of the present state of the art of pediatric clinical pharmacology including developmental physiology, pediatric-specific pathology, special tools and methods for development of drugs for children (assessment of efficacy, toxicity, long-term safety etc.) as well as regulatory and ethical knowledge and skills. In the future, structural and educational changes have to lead back to a closer cooperation and interaction of pediatrics with (clinical) pharmacology and pharmacy.

Heparin - A Century of Progress

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Publisher : Springer Science & Business Media
ISBN 13 : 3642230563
Total Pages : 457 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Heparin - A Century of Progress by : Rebecca Lever

Download or read book Heparin - A Century of Progress written by Rebecca Lever and published by Springer Science & Business Media. This book was released on 2012-05-08 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.

Modern Anesthetics

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3540748067
Total Pages : 497 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Modern Anesthetics by : Jürgen Schüttler

Download or read book Modern Anesthetics written by Jürgen Schüttler and published by Springer Science & Business Media. This book was released on 2008-01-08 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some important constraints of anesthesia must be taken into consideration when the pharmacological properties of modern anesthetics are discussed. The most imp- tant of these could be that the target effect be achieved preferably within seconds, at most within a few minutes. Similarly, offset of drug action should be achieved within minutes rather hours. The target effects, such as unconsciousness, are pot- tially life-threatening, as are the side effects of modern anesthetics, such as respi- tory and cardiovascular depression. Finally, the patient’s purposeful responses are not available to guide drug dosage, because, either the patient is unconscious, or more problematically, the patient is aware but unable to communicate pain because of neuromuscular blockade. These constraints were already recognised 35 years ago, when in 1972 Volume XXX entitled “Modern Inhalation Anesthetics” appeared in this Handbook Series. The present volume is meant as a follow up and extension of that volume. At the beginning of the 1970’s anesthesia was commonly delivered by inhalation, with only very few exceptions. The clinical understanding of that time considered anesthesia as a unique state achieved by any of the inhalation anesthetics, in- pendent of their specific molecular structure. “The very mechanism of anesthetic action at the biophase” was discussed within the theoretical framework of the “u- tary theory of narcosis”.

Reactive Oxygen Species

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Author :
Publisher : Springer Nature
ISBN 13 : 3030685101
Total Pages : 425 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Reactive Oxygen Species by : Harald H. H. W. Schmidt

Download or read book Reactive Oxygen Species written by Harald H. H. W. Schmidt and published by Springer Nature. This book was released on 2021-02-23 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Drug Transporters

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Publisher : Springer Science & Business Media
ISBN 13 : 3642145418
Total Pages : 457 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Drug Transporters by : Martin F. Fromm

Download or read book Drug Transporters written by Martin F. Fromm and published by Springer Science & Business Media. This book was released on 2010-11-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.

Antidepressants: Past, Present and Future

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540430544
Total Pages : 644 pages
Book Rating : 4.4/5 (35 download)

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Book Synopsis Antidepressants: Past, Present and Future by : Renato D. Alarcón

Download or read book Antidepressants: Past, Present and Future written by Renato D. Alarcón and published by Springer Science & Business Media. This book was released on 2004-02-19 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contribution by numerous experts

Stem Cells

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Publisher : Springer Science & Business Media
ISBN 13 : 354031265X
Total Pages : 414 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Stem Cells by : Anna M. Wobus

Download or read book Stem Cells written by Anna M. Wobus and published by Springer Science & Business Media. This book was released on 2006-01-31 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This hugely important volume presents in a single text many novel aspects of stem cell biology with respect to scientific endeavors and future applications. During the past few years, stem cell research has metamorphosed into distinct and specialized avenues of research. What makes this book unique is that it not only covers these varied areas of research, but examines in detail some of the key pharmacological issues that up to now have not been addressed in a single volume.

Drug Delivery

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Publisher : Springer Science & Business Media
ISBN 13 : 3642004776
Total Pages : 506 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Drug Delivery by : Monika Schäfer-Korting

Download or read book Drug Delivery written by Monika Schäfer-Korting and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering today’s options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.

Anabolic-Androgenic Steroids

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642663532
Total Pages : 744 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Anabolic-Androgenic Steroids by : Charles D. Kochakian

Download or read book Anabolic-Androgenic Steroids written by Charles D. Kochakian and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume was planned to provide a comprehensive survey of the role of the anabolic-androgenic steroids in the vital economy exclusive of the androgenic (sexual) functions. It seemed appropriate to bring together all of this information in an organized fashion in one volume at this time not only to serve as a source of information but also to indicate and suggest areas that need further exploration. The anabolic action of the steroid hormones has gone through a period of great activity in both basic and clinical research. A complete understanding of the manifold anabolic effects still remains to be elucidated and the art of clinical application is only gradually becoming apparent. This volume should be useful not only to the experienced investigator in both basic and clinical research but also for the novice. Furthermore, it should serve as a source of information for the careful use of these steroids in certain metabolic diseases. These steroids have had wide clinical application with variable results. In many instances further careful exploration is suggested. Other instances have demonstrated varying degrees of usefulness.

Practical Manual of Experimental and Clinical Pharmacology

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Author :
Publisher : Jaypee Brothers,Medical Publishers Pvt. Limited
ISBN 13 : 9789386150721
Total Pages : 430 pages
Book Rating : 4.1/5 (57 download)

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Book Synopsis Practical Manual of Experimental and Clinical Pharmacology by : Bikash Mehdi

Download or read book Practical Manual of Experimental and Clinical Pharmacology written by Bikash Mehdi and published by Jaypee Brothers,Medical Publishers Pvt. Limited. This book was released on 2016-10-26 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: