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Book Synopsis Green Fluorescent Protein by : Martin Chalfie
Download or read book Green Fluorescent Protein written by Martin Chalfie and published by John Wiley & Sons. This book was released on 2005-11-18 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of the gene for green fluorescent protein (GFP), derived from jellyfish, this protein that emits a green glow has initiated a revolution in molecular biosciences. With this tool, it is now possible to visualize nearly any protein of interest in any cell or tissue of any species. Since the publication of the first edition, there have been tremendously significant technological advances, including development of new mutant variants. Proteins are now available in yellow and blue, and Novel Fluorescent Proteins (NFPs) have expanded their utility in developing biosensors, biological markers, and other biological applications. This updated, expanded new edition places emphasis on the rise of NFPs, including new chapters on NFP properties with detailed protocols, applications of GFPs and NFPs in industry research, and biosensors. This book provides a solid theoretical framework, along with detailed, practical guidance on use of GFPs and NFPs with discussion of potential pitfalls. The expert contributors provide real examples in showing how to tailor GFP/NFP to specific systems, maximize expression, and enhance detection.
Book Synopsis Luminous Pursuit: Jellyfish, Gfp, And The Unforeseen Path To The Nobel Prize by : Osamu Shimomura
Download or read book Luminous Pursuit: Jellyfish, Gfp, And The Unforeseen Path To The Nobel Prize written by Osamu Shimomura and published by World Scientific. This book was released on 2017-05-23 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book narrates the uniquely intertwined life and scientific career of Nobel laureate Osamu Shimomura, with particular attention to his discovery of aequorin and Green Fluorescent Protein (GFP). It includes his early memories of Manchuria and wartime Japan featuring an eyewitness account of the atomic bombing of Nagasaki, his postwar studies and his travels to collect and research more than fifteen bioluminescent species, in locations ranging from Japan to San Juan Island, Bermuda, New Zealand and Norway. Dr Shimomura describes the unique combination of serendipity and perseverance that led ultimately to his 2008 Nobel Prize in chemistry. The book provides an engaging account of the life of a dedicated scientist, emphasizing the value of determination in the pursuit of pure scientific knowledge, and showing how a general understanding of science helped him open up new areas of research that have led to unforeseen applications in cell biology and medicine.
Book Synopsis GFP Whole Cell Microbial Biosensors by : Frank Delvigne
Download or read book GFP Whole Cell Microbial Biosensors written by Frank Delvigne and published by Momentum Press. This book was released on 2013-01-09 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two strategies are usually considered for the optimization of microbial bioprocesses. The first one involves genetic or metabolic engineering of the target microbial strains in order to improve its production efficiency or its tolerance to adverse conditions. The second one is based on the chemical engineering improvement of the bioreactors and scaling-up rules. This work is more particularly dedicated to this second class of parameters. Recent developments in bioreactor technologies follow the scaling-out principle, i.e. carrying out several cultures in parallel with controlled conditions for screening purposes. Several mini-bioreactor concepts, i.e. bioreactor with working volume of 1 to 100 mL with controlling devices, have been developed following this principle. In general, chemical engineering similarities between conventional stirred bioreactors and their miniature equivalent are well characterized. However, the actual scaling-up rules are not able to cope with the complexity of the microbial stress response. Indeed, microbial stress response still remains not completely understood considering the process perturbations and the environmental fluctuations accompanying the scaling-up to industrial bioreactors. At this time, this kind of response can only be experimentally predicted by using scale-down bioreactors, i.e. lab-scale bioreactors designed in order to reproduce mixing imperfections that have to be expected at large-scale. However, the use of such an approach is time consuming and requires an experimented staff to elaborate the scaling-down protocols. Indeed, bioprocess development involves several steps which cannot be necessarily linked with each other considering the different cultivation equipment used.
Book Synopsis Aglow in the Dark by : Vincent Pieribone
Download or read book Aglow in the Dark written by Vincent Pieribone and published by Harvard University Press. This book was released on 2005 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of green fluorescent protein revolutionized molecular biology, transforming our study of everything from the AIDS virus to the workings of the brain.
Book Synopsis The General Factor of Personality by : Janek Musek
Download or read book The General Factor of Personality written by Janek Musek and published by Academic Press. This book was released on 2017-05-04 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: The General Factor of Personality improves our understanding of the personality structure and the relations between major personality dimensions, as well as major dimensions of the entire non-cognitive sphere of psychological variables. The results of the empirical testing and theoretical evaluations in this book contribute to the more comprehensive and precise theoretical framework of the General Factor of Personality (GFP) and that of the entire personality structure. Additionally, the book answers some unresolved questions concerning the nature of the GFP, including whether it is based more on correlations in real behavior or on other less substantial factors between lower-order dimensions of personality. This book is crucially important not only for theoretical reasons, but also for the tremendous practical and applied value of the assumed general dimension of personality. As a common denominator of all the most important fields of personality beyond cognition (Big Five, well-being, coping, emotionality, motivation, self-concept, self-esteem, control, wisdom and others), the GFP represents an extremely strong single predictor of the quality of life, mental health and well-being, career, academic success, and the quality of family and interpersonal relations. - Reviews the theoretical and methodological work on the General Factor of Personality (GFP) - Presents major research results in the field of GFP and the dimensional structure of personality - Provides a balanced and objective approach to the topic of GFP, addressing criticisms and controversies - Considers the practical and applied aspects of this research - Draws conclusions on the bioevolutionary model of GFP to give a more thorough understanding of biological bases of human personality
Book Synopsis Cell Biology by the Numbers by : Ron Milo
Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Book Synopsis Guide to Yeast Genetics and Molecular and Cell Biology, Part C by : Gerald R. Fink
Download or read book Guide to Yeast Genetics and Molecular and Cell Biology, Part C written by Gerald R. Fink and published by Gulf Professional Publishing. This book was released on 2002 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume and its companion, Volume 350, are specifically designed to meet the needs of graduate students and postdoctoral students as well as researchers, by providing all the up-to-date methods necessary to study genes in yeast. Procedures are included that enable newcomers to set up a yeast laboratory and to master basic manipulations. Relevant background and reference information given for procedures can be used as a guide to developing protocols in a number of disciplines. Specific topics addressed in this book include cytology, biochemistry, cell fractionation, and cell biology.
Book Synopsis Genetic Techniques for Biological Research by : Corinne A. Michels
Download or read book Genetic Techniques for Biological Research written by Corinne A. Michels and published by John Wiley & Sons. This book was released on 2002-06-10 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Genetic Analysis is an advanced textbook to teach the theory and practice of molecular genetic analysis to senior undergraduates and graduates studying genetics, molecular biology and cell biology. This book uses a case study approach, with the yeast Saccharomyces as the model genetic organism, to explain the theory and practice of molecular genetic analysis. It provides enough information so readers will be able to apply the approach to their own research project.
Book Synopsis RNA Interference Technology by : Krishnarao Appasani
Download or read book RNA Interference Technology written by Krishnarao Appasani and published by Cambridge University Press. This book was released on 2005-01-17 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA Interference (RNAi) technology has rapidly become one of the key methods used in functional genomics. RNAi is used to block the expression of genes and create phenotypes that can potentially yield clues about the function of these genes. In the postgenomic era, the elucidation of the physiological function of genes has become the rate-limiting step in the quest to develop 'gene-based drugs' and RNAi could potentially play a pivotal role in the validation of such novel drugs. In this overview, the basic concepts and applications of RNAi biology are discussed. Leading experts from both academia and industry have contributed to this invaluable reference. The volume is forwarded by Andrew Fire, one of the winners of the 2006 Nobel Prize for the discovery of RNA Interference.
Book Synopsis Vascular Biochemistry by : Peter Zahradka
Download or read book Vascular Biochemistry written by Peter Zahradka and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores all aspects of vascular biochemistry and includes chapters that provide an understanding of vascular function with descriptions of tissue components present in the vascular wall as well as an exploration of the hemodynamic and metabolic activities associated with this function. In addition, some chapters explore the vasculature under conditions which mimic various disease states. The information provided in this volume will provide new insights into the mechanisms that control vascular function as well as therapies designed to treat vascular disease.
Book Synopsis New Insights in Anaphylaxis by : Vanesa Esteban
Download or read book New Insights in Anaphylaxis written by Vanesa Esteban and published by Frontiers Media SA. This book was released on 2018-04-20 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anaphylaxis has usually been studied and understood from an immunological view and the main lethal effects involve the cardio-vascular system. Despite exhaustive efforts exerted in this area of research, much more investigation is needed to mitigate, recognize or prevent this disease. The scope of this Research Topic is to present and discuss the current knowledge of anaphylaxis, from the clinic to the underlying molecular mechanisms. We are thankful to the medical doctors, researchers, and colleagues who have contributed to this issue, as it would not have been possible without their highly valuable expertise in allergy and anaphylaxis research.
Book Synopsis Biology of Nematodes: Current Studies by : R. Behme
Download or read book Biology of Nematodes: Current Studies written by R. Behme and published by Ardent Media. This book was released on 1972 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Plant Glycobiology - A Sweet World of Glycans, Glycoproteins, Glycolipids, and Carbohydrate-Binding Proteins by : Els J. M. Van Damme
Download or read book Plant Glycobiology - A Sweet World of Glycans, Glycoproteins, Glycolipids, and Carbohydrate-Binding Proteins written by Els J. M. Van Damme and published by Frontiers Media SA. This book was released on 2021-10-21 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Retinoids written by Pascal Dollé and published by John Wiley & Sons. This book was released on 2015-05-18 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Retinoids: Biology, Biochemistry, and Disease provides an overview and synthesis of the retinoid molecules, from basic biology to mechanisms of diseases and therapy. Divided into five sections, the book covers retinoic acid signaling from biochemical, genetic, developmental, and clinical perspectives. The text is divided into five sections, the first of which examines vitamin A metabolic and enzymatic pathways. Focus then shifts to the role of retinoic acid signaling in development, and then to retinoids and physiological function. The book concludes with chapters on retinoids, disease and therapy. Comprehensive in scope and written by leading researchers in the field, The Retinoids: Biology, Biochemistry, and Disease will be an essential reference for biologists, biochemists, geneticists and developmental biologists, as well as for clinicians and pharmacists engaged in clinical research involving retinoids.
Author :Vinagolu K. Rajasekhar Publisher :Springer Science & Business Media ISBN 13 :1603272275 Total Pages :590 pages Book Rating :4.6/5 (32 download)
Book Synopsis Regulatory Networks in Stem Cells by : Vinagolu K. Rajasekhar
Download or read book Regulatory Networks in Stem Cells written by Vinagolu K. Rajasekhar and published by Springer Science & Business Media. This book was released on 2009-03-04 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells appear to be fundamental cellular units associated with the origin of multicellular organisms and have evolved to function in safeguarding the cellular homeostasis in organ t- sues. The characteristics of stem cells that distinguish them from other cells have been the fascinating subjects of stem cell research. The important properties of stem cells, such as ma- tenance of quiescence, self-renewal capacity, and differentiation potential, have propelled this exciting ?eld and presently form a common theme of research in developmental biology and medicine. The derivation of pluripotent embryonic stem cells, the prospective identi?cation of multipotent adult stem cells, and, more recently, the induced pluripotent stem cells (popularly called iPS) are important milestones in the arena of stem cell biology. Complex networks of transcription factors, different signaling molecules, and the interaction of genetic and epi- netic events constantly modulate stem cell behavior to evoke programming and reprogramming processes in normal tissue homeostasis during development. In any given cellular scenario, the regulatory networks can pose considerable complexity and yet exert an orderly control of stem cell differentiation during normal development. An aberration in these ?nely tuned processes during development usually results in a spectrum of diseases such as cancers and neurological disorders. Thisunderscorestheimminentneedforamorecompleteunderstandingofmolecular mechanisms underlying the regulatory circuitries required for stem cell maintenance. Overthepast3–5years,adiversegroupofbenchandphysicianscientistshaveprospectively enhanced our knowledge of stem cell biology. These studies are unveiling many unrecognized or previously unknown fundamentals of developmental biology.
Book Synopsis Heart Failure: A Companion to Braunwald's Heart Disease E-Book by : G. Michael Felker
Download or read book Heart Failure: A Companion to Braunwald's Heart Disease E-Book written by G. Michael Felker and published by Elsevier Health Sciences. This book was released on 2019-02-06 with total page 937 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date, authoritative and comprehensive, Heart Failure, 4th Edition, provides the clinically relevant information you need to effectively manage and treat patients with this complex cardiovascular problem. This fully revised companion to Braunwald's Heart Disease helps you make the most of new drug therapies such as angiotensin receptor neprilysin inhibitors (ARNIs), recently improved implantable devices, and innovative patient management strategies. Led by internationally recognized heart failure experts Dr. G. Michael Felker and Dr. Douglas Mann, this outstanding reference gives health care providers the knowledge to improve clinical outcomes in heart failure patients. - Focuses on a clinical approach to treating heart failure, resulting from a broad variety of cardiovascular problems. - Covers the most recent guidelines and protocols, including significant new updates to ACC, AHA, and HFSA guidelines. - Covers key topics such as biomarkers and precision medicine in heart failure and new data on angiotensin receptor neprilysin inhibitors (ARNIs). - Contains four new chapters: Natriuretic Peptides in Heart Failure; Amyloidosis as a Cause of Heart Failure; HIV and Heart Failure; and Neuromodulation in Heart Failure. - Covers the pathophysiological basis for the development and progression of heart failure. - Serves as a definitive resource to prepare for the ABIM's Heart Failure board exam. - 2016 British Medical Association Award: First Prize, Cardiology (3rd Edition).
Download or read book Bacterial Pathogenesis written by and published by Academic Press. This book was released on 1998-07-01 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. - Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease - Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow - Covers safety aspects, detection, identification and speciation - Includes techniques for the study of host interactions and reactions in animals and plants - Describes biochemical and molecular genetic approaches - Essential methods for gene expression and analysis - Covers strategies and problems for disease control
