Regulatory Networks In Stem Cells

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Regulatory Networks in Stem Cells

Author : Vinagolu K. Rajasekhar
Publisher : Springer Science & Business Media
ISBN 13 : 1603272275
Total Pages : 590 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Regulatory Networks in Stem Cells by : Vinagolu K. Rajasekhar

Download or read book Regulatory Networks in Stem Cells written by Vinagolu K. Rajasekhar and published by Springer Science & Business Media. This book was released on 2009-03-04 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells appear to be fundamental cellular units associated with the origin of multicellular organisms and have evolved to function in safeguarding the cellular homeostasis in organ t- sues. The characteristics of stem cells that distinguish them from other cells have been the fascinating subjects of stem cell research. The important properties of stem cells, such as ma- tenance of quiescence, self-renewal capacity, and differentiation potential, have propelled this exciting ?eld and presently form a common theme of research in developmental biology and medicine. The derivation of pluripotent embryonic stem cells, the prospective identi?cation of multipotent adult stem cells, and, more recently, the induced pluripotent stem cells (popularly called iPS) are important milestones in the arena of stem cell biology. Complex networks of transcription factors, different signaling molecules, and the interaction of genetic and epi- netic events constantly modulate stem cell behavior to evoke programming and reprogramming processes in normal tissue homeostasis during development. In any given cellular scenario, the regulatory networks can pose considerable complexity and yet exert an orderly control of stem cell differentiation during normal development. An aberration in these ?nely tuned processes during development usually results in a spectrum of diseases such as cancers and neurological disorders. Thisunderscorestheimminentneedforamorecompleteunderstandingofmolecular mechanisms underlying the regulatory circuitries required for stem cell maintenance. Overthepast3–5years,adiversegroupofbenchandphysicianscientistshaveprospectively enhanced our knowledge of stem cell biology. These studies are unveiling many unrecognized or previously unknown fundamentals of developmental biology.

Regulatory Networks in Stem Cells

Author : Vinagolu K. Rajasekhar
Publisher : Humana Press
ISBN 13 : 9781603272261
Total Pages : 601 pages
Book Rating : 4.2/5 (722 download)

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Book Synopsis Regulatory Networks in Stem Cells by : Vinagolu K. Rajasekhar

Download or read book Regulatory Networks in Stem Cells written by Vinagolu K. Rajasekhar and published by Humana Press. This book was released on 2009-03-19 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells appear to be fundamental cellular units associated with the origin of multicellular organisms and have evolved to function in safeguarding the cellular homeostasis in organ t- sues. The characteristics of stem cells that distinguish them from other cells have been the fascinating subjects of stem cell research. The important properties of stem cells, such as ma- tenance of quiescence, self-renewal capacity, and differentiation potential, have propelled this exciting ?eld and presently form a common theme of research in developmental biology and medicine. The derivation of pluripotent embryonic stem cells, the prospective identi?cation of multipotent adult stem cells, and, more recently, the induced pluripotent stem cells (popularly called iPS) are important milestones in the arena of stem cell biology. Complex networks of transcription factors, different signaling molecules, and the interaction of genetic and epi- netic events constantly modulate stem cell behavior to evoke programming and reprogramming processes in normal tissue homeostasis during development. In any given cellular scenario, the regulatory networks can pose considerable complexity and yet exert an orderly control of stem cell differentiation during normal development. An aberration in these ?nely tuned processes during development usually results in a spectrum of diseases such as cancers and neurological disorders. Thisunderscorestheimminentneedforamorecompleteunderstandingofmolecular mechanisms underlying the regulatory circuitries required for stem cell maintenance. Overthepast3–5years,adiversegroupofbenchandphysicianscientistshaveprospectively enhanced our knowledge of stem cell biology. These studies are unveiling many unrecognized or previously unknown fundamentals of developmental biology.

Transcription Factor Regulatory Networks

Author : Qi Song
Publisher : Springer Nature
ISBN 13 : 1071628151
Total Pages : 229 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Transcription Factor Regulatory Networks by : Qi Song

Download or read book Transcription Factor Regulatory Networks written by Qi Song and published by Springer Nature. This book was released on 2022-10-20 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers various state-of-the-art techniques regarding the associations between transcription factors (TFs) and genes, with a focus on providing methodological and practical references for researchers. The contents cover diverse protocols and summaries of TFs including screening of TF-DNA interactions, detection of open chromatin regions, identification of epigenetic regulations, engineering TFs with genome editing tools, detection of transcriptional activities, computational analysis of TF networks, functions and druggabilities of TFs in biomedical research, and much more. Written for the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed implementation advice from the experts to ensure successful research results. Authoritative and cutting-edge, Transcription Factor Regulatory Networks aims to benefit readers who are interested in using state-of-the-art techniques to study TFs and their myriad effects in cellular life.

Regulatory Networks of Hematopoietic Stem Cells and Their Micro-environment

Author : Baiba Vilne
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (94 download)

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Book Synopsis Regulatory Networks of Hematopoietic Stem Cells and Their Micro-environment by : Baiba Vilne

Download or read book Regulatory Networks of Hematopoietic Stem Cells and Their Micro-environment written by Baiba Vilne and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gene Regulatory Networks in Plant Stem Cells

Author : Aylin S. Haas
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)

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Book Synopsis Gene Regulatory Networks in Plant Stem Cells by : Aylin S. Haas

Download or read book Gene Regulatory Networks in Plant Stem Cells written by Aylin S. Haas and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computational Stem Cell Biology

Author : Patrick Cahan
Publisher : Humana
ISBN 13 : 9781493992232
Total Pages : 0 pages
Book Rating : 4.9/5 (922 download)

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Book Synopsis Computational Stem Cell Biology by : Patrick Cahan

Download or read book Computational Stem Cell Biology written by Patrick Cahan and published by Humana. This book was released on 2019-05-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details methods and protocols to further the study of stem cells within the computational stem cell biology (CSCB) field. Chapters are divided into four sections covering the theory and practice of modeling of stem cell behavior, analyzing single cell genome-scale measurements, reconstructing gene regulatory networks, and metabolomics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Stem Cell Biology: Methods and Protocols will be an invaluable guide to researchers as they explore stem cells from the perspective of computational biology.

Stem Cell Transcriptional Networks

Author : Benjamin L Kidder
Publisher : Humana Press
ISBN 13 : 9781493905133
Total Pages : 286 pages
Book Rating : 4.9/5 (51 download)

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Book Synopsis Stem Cell Transcriptional Networks by : Benjamin L Kidder

Download or read book Stem Cell Transcriptional Networks written by Benjamin L Kidder and published by Humana Press. This book was released on 2014-04-18 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Transcriptional Networks: Methods and Protocols collects techniques used to increase our understanding of the underlying transcriptional programs of stem cells that promote self-renewal and differentiation. The volume opens with a section on next-generation sequencing library preparation and data analysis. Continuing with a collection of protocols on visual analysis and interpretation of large-scale interaction networks, this detailed compilation features transcriptional networks in embryonic and adult stem cells, embryo culture and derivation of stem cells, as well as transcriptional programs that promote self-renewal, reprogramming, and transdifferentiation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Stem Cell Transcriptional Networks: Methods and Protocols aims to provide a key resource for biologists seeking to interrogate these vital networks.

New Frontiers of Network Analysis in Systems Biology

Author : Avi Ma'ayan
Publisher : Springer Science & Business Media
ISBN 13 : 9400743300
Total Pages : 204 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis New Frontiers of Network Analysis in Systems Biology by : Avi Ma'ayan

Download or read book New Frontiers of Network Analysis in Systems Biology written by Avi Ma'ayan and published by Springer Science & Business Media. This book was released on 2012-06-25 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly developing field of systems biology is influencing many aspects of biological research and is expected to transform biomedicine. Some emerging offshoots and specialized branches in systems biology are receiving particular attention and are becoming highly active areas of research. This collection of invited reviews describes some of the latest cutting-edge experimental and computational advances in these emerging sub-fields of systems biology. In particular, this collection focuses on the study of mammalian embryonic stem cells; new technologies involving mass-spectrometry proteomics; single cell measurements; methods for modeling complex stochastic systems; network-based classification algorithms; and the revolutionary emerging field of systems pharmacology.

Molecular Basis of Developmental and Stem Cell Regulation

Author : Hisato Kondoh
Publisher : Springer Nature
ISBN 13 : 303139027X
Total Pages : 260 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Molecular Basis of Developmental and Stem Cell Regulation by : Hisato Kondoh

Download or read book Molecular Basis of Developmental and Stem Cell Regulation written by Hisato Kondoh and published by Springer Nature. This book was released on with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computational Biology of Embryonic Stem Cells

Author : Ming Zhan
Publisher : Bentham Science Publishers
ISBN 13 : 1608050254
Total Pages : 262 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Computational Biology of Embryonic Stem Cells by : Ming Zhan

Download or read book Computational Biology of Embryonic Stem Cells written by Ming Zhan and published by Bentham Science Publishers. This book was released on 2012-08-10 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Computational biology in combination with large-scale biology has played a critical role in exploring the great potentials of embryonic stem cells, resulting in significant discoveries. This e-book brings together reviews and essays from different aspects"

RNAi and MicroRNA-Mediated Gene Regulation in Stem Cells

Author : Baohong Zhang
Publisher : Methods in Molecular Biology
ISBN 13 :
Total Pages : 286 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis RNAi and MicroRNA-Mediated Gene Regulation in Stem Cells by : Baohong Zhang

Download or read book RNAi and MicroRNA-Mediated Gene Regulation in Stem Cells written by Baohong Zhang and published by Methods in Molecular Biology. This book was released on 2010-08-16 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.

Gene Regulatory Networks in Plant Stem Cells

Author : Aylin Sibel Haas
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)

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Book Synopsis Gene Regulatory Networks in Plant Stem Cells by : Aylin Sibel Haas

Download or read book Gene Regulatory Networks in Plant Stem Cells written by Aylin Sibel Haas and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computational Biology for Stem Cell Research

Author : Pawan Raghav
Publisher : Elsevier
ISBN 13 : 0443132216
Total Pages : 568 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Computational Biology for Stem Cell Research by : Pawan Raghav

Download or read book Computational Biology for Stem Cell Research written by Pawan Raghav and published by Elsevier. This book was released on 2024-01-12 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Biology for Stem Cell Research is an invaluable guide for researchers as they explore HSCs and MSCs in computational biology. With the growing advancement of technology in the field of biomedical sciences, computational approaches have reduced the financial and experimental burden of the experimental process. In the shortest span, it has established itself as an integral component of any biological research activity. HSC informatics (in silico) techniques such as machine learning, genome network analysis, data mining, complex genome structures, docking, system biology, mathematical modeling, programming (R, Python, Perl, etc.) help to analyze, visualize, network constructions, and protein-ligand or protein-protein interactions. This book is aimed at beginners with an exact correlation between the biomedical sciences and in silico computational methods for HSCs transplantation and translational research and provides insights into methods targeting HSCs properties like proliferation, self-renewal, differentiation, and apoptosis. Modeling Stem Cell Behavior: Explore stem cell behavior through animal models, bridging laboratory studies to real-world clinical allogeneic HSC transplantation (HSCT) scenarios. Bioinformatics-Driven Translational Research: Navigate a path from bench to bedside with cutting-edge bioinformatics approaches, translating computational insights into tangible advancements in stem cell research and medical applications. Interdisciplinary Resource: Discover a single comprehensive resource catering to biomedical sciences, life sciences, and chemistry fields, offering essential insights into computational tools vital for modern research.

Stem Cells, Tissue Regeneration and Repair

Author : Ursula Just
Publisher :
ISBN 13 : 9783805585637
Total Pages : 0 pages
Book Rating : 4.5/5 (856 download)

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Book Synopsis Stem Cells, Tissue Regeneration and Repair by : Ursula Just

Download or read book Stem Cells, Tissue Regeneration and Repair written by Ursula Just and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special issue presents recent work from the frontiers of stem cell research, highlighting developments in the rapidly evolving fields of embryonal and adult stem cell biology and tackling key issues relevant to the development of novel therapies. From the arena of basic research, special consideration is given to the gene expression patterns and regulatory networks associated with maintaining potential and coordinating differentiation as well as to ways in which stem cells are influenced by surrounding cells in the niche, thus providing a view of both intrinsic and extrinsic control mechanisms which act together to determine cell fate. On a more applied level, model applications of stem cell therapies in tissues such as muscle, nerve, liver and pancreas serve on the one hand to illustrate the enormous potential of stem cell therapy to regenerate disease-damaged tissue, and on the other hand to reveal the problems associated with translating these hopes into practice.

Integration of Molecular Regulatory Networks

Author : Robert Sehlke
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (122 download)

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Book Synopsis Integration of Molecular Regulatory Networks by : Robert Sehlke

Download or read book Integration of Molecular Regulatory Networks written by Robert Sehlke and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Models of Cellular Regulation

Author : Baltazar Aguda
Publisher : Oxford University Press
ISBN 13 : 0198570910
Total Pages : 199 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Models of Cellular Regulation by : Baltazar Aguda

Download or read book Models of Cellular Regulation written by Baltazar Aguda and published by Oxford University Press. This book was released on 2008-07-31 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the mechanisms and models linking the realms of molecular interactions and biological processes or functions. It addresses the need of mathematical modelers to learn how to formulate models of cellular processes and to understand how quantitative modeling can help sort through the complexities of molecular regulatory networks.

Stochastic Analysis of Nonlinear Dynamics and Feedback Control for Gene Regulatory Networks with Applications to Synthetic Biology

Download Stochastic Analysis of Nonlinear Dynamics and Feedback Control for Gene Regulatory Networks with Applications to Synthetic Biology PDF Online Free

Author : Natalja Strelkowa
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (93 download)

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Book Synopsis Stochastic Analysis of Nonlinear Dynamics and Feedback Control for Gene Regulatory Networks with Applications to Synthetic Biology by : Natalja Strelkowa

Download or read book Stochastic Analysis of Nonlinear Dynamics and Feedback Control for Gene Regulatory Networks with Applications to Synthetic Biology written by Natalja Strelkowa and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: