Genetic Variation and Human Disease

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Publisher : Cambridge University Press
ISBN 13 : 9780521336604
Total Pages : 384 pages
Book Rating : 4.3/5 (366 download)

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Book Synopsis Genetic Variation and Human Disease by : Kenneth M. Weiss

Download or read book Genetic Variation and Human Disease written by Kenneth M. Weiss and published by Cambridge University Press. This book was released on 1993 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in molecular and computational methods have made it possible to identify the genetic basis of any biological trait, and have led to spectacular advances in the study of human disease. This book provides an overview of the concepts and methods needed to understand the genetic basis of biological traits, including disease, in humans. Using examples of qualitative and quantitative phenotypes, Professor Weiss shows how genetic variation may be quantified, and how relationships between genotype and phenotype may be inferred. This book will appeal to many biologists and biological anthropologists interested in the genetic basis of biological traits, as well as to epidemiologists, biomedical scientists, human geneticists and molecular biologists.

Genetic Variation

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Publisher : BoD – Books on Demand
ISBN 13 : 183881096X
Total Pages : 298 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Genetic Variation by : Rafael Trindade Maia

Download or read book Genetic Variation written by Rafael Trindade Maia and published by BoD – Books on Demand. This book was released on 2021-05-19 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic diversity is one of the measures of biodiversity and has consequences in biological variation. It is crucial to understand the evolutionary and adaptative processes in all living species. This book is an interdisciplinary and integrated work that will contribute to the knowledge of academics from different areas of biological sciences. This collection of scientific papers was chosen and analyzed to offer readers a broad and integrated view of the importance of genetic diversity in the evolution and adaptation of living beings, as well as practical applications of the information needed to analyze this diversity in different organisms. This book was edited by geneticist researchers and provides academics with up-to-date and quality information on the subject.

Evaluating Human Genetic Diversity

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Publisher : National Academies Press
ISBN 13 : 0309184746
Total Pages : 101 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Evaluating Human Genetic Diversity by : National Research Council

Download or read book Evaluating Human Genetic Diversity written by National Research Council and published by National Academies Press. This book was released on 1998-01-19 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.

In the Light of Evolution

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Publisher :
ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis In the Light of Evolution by : National Academy of Sciences

Download or read book In the Light of Evolution written by National Academy of Sciences and published by . This book was released on 2007 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.

Eco-Evolutionary Dynamics

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Publisher : Academic Press
ISBN 13 : 0128014334
Total Pages : 392 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Eco-Evolutionary Dynamics by :

Download or read book Eco-Evolutionary Dynamics written by and published by Academic Press. This book was released on 2014-08-12 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The theme of this volume is to discuss Eco-evolutionary Dynamics. - Updates and informs the reader on the latest research findings - Written by leading experts in the field - Highlights areas for future investigation

An Evidence Framework for Genetic Testing

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Publisher : National Academies Press
ISBN 13 : 0309453291
Total Pages : 149 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis An Evidence Framework for Genetic Testing by : National Academies of Sciences, Engineering, and Medicine

Download or read book An Evidence Framework for Genetic Testing written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-04-21 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care.

Human Variation

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Publisher :
ISBN 13 : 9781936113255
Total Pages : 200 pages
Book Rating : 4.1/5 (132 download)

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Book Synopsis Human Variation by : Aravinda Chakravarti

Download or read book Human Variation written by Aravinda Chakravarti and published by . This book was released on 2014 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A subject collection from Cold Spring Harbor perspectives in medicine."

Biosocial Surveys

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Publisher : National Academies Press
ISBN 13 : 0309108675
Total Pages : 429 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biosocial Surveys by : National Research Council

Download or read book Biosocial Surveys written by National Research Council and published by National Academies Press. This book was released on 2008-01-06 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosocial Surveys analyzes the latest research on the increasing number of multipurpose household surveys that collect biological data along with the more familiar interviewerâ€"respondent information. This book serves as a follow-up to the 2003 volume, Cells and Surveys: Should Biological Measures Be Included in Social Science Research? and asks these questions: What have the social sciences, especially demography, learned from those efforts and the greater interdisciplinary communication that has resulted from them? Which biological or genetic information has proven most useful to researchers? How can better models be developed to help integrate biological and social science information in ways that can broaden scientific understanding? This volume contains a collection of 17 papers by distinguished experts in demography, biology, economics, epidemiology, and survey methodology. It is an invaluable sourcebook for social and behavioral science researchers who are working with biosocial data.

Understanding Racial and Ethnic Differences in Health in Late Life

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Publisher : National Academies Press
ISBN 13 : 0309165865
Total Pages : 184 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Understanding Racial and Ethnic Differences in Health in Late Life by : National Research Council

Download or read book Understanding Racial and Ethnic Differences in Health in Late Life written by National Research Council and published by National Academies Press. This book was released on 2004-09-08 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the population of older Americans grows, it is becoming more racially and ethnically diverse. Differences in health by racial and ethnic status could be increasingly consequential for health policy and programs. Such differences are not simply a matter of education or ability to pay for health care. For instance, Asian Americans and Hispanics appear to be in better health, on a number of indicators, than White Americans, despite, on average, lower socioeconomic status. The reasons are complex, including possible roles for such factors as selective migration, risk behaviors, exposure to various stressors, patient attitudes, and geographic variation in health care. This volume, produced by a multidisciplinary panel, considers such possible explanations for racial and ethnic health differentials within an integrated framework. It provides a concise summary of available research and lays out a research agenda to address the many uncertainties in current knowledge. It recommends, for instance, looking at health differentials across the life course and deciphering the links between factors presumably producing differentials and biopsychosocial mechanisms that lead to impaired health.

Genetic Variation

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Publisher : CSHL Press
ISBN 13 : 0879697806
Total Pages : 472 pages
Book Rating : 4.8/5 (796 download)

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Book Synopsis Genetic Variation by : Michael P. Weiner

Download or read book Genetic Variation written by Michael P. Weiner and published by CSHL Press. This book was released on 2007 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first compendium of protocols specifically geared towards genetic variation studies. It includes detailed step-by-step experimental protocols that cover the complete spectrum of genetic variation in humans and model organisms, along with advice on study design and analyzing data.

Theories of Population Variation in Genes and Genomes

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Publisher : Princeton University Press
ISBN 13 : 0691165890
Total Pages : 431 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis Theories of Population Variation in Genes and Genomes by : Freddy Bugge Christiansen

Download or read book Theories of Population Variation in Genes and Genomes written by Freddy Bugge Christiansen and published by Princeton University Press. This book was released on 2014-11-23 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an authoritative introduction to both classical and coalescent approaches to population genetics. Written for graduate students and advanced undergraduates by one of the world's leading authorities in the field, the book focuses on the theoretical background of population genetics, while emphasizing the close interplay between theory and empiricism. Traditional topics such as genetic and phenotypic variation, mutation, migration, and linkage are covered and advanced by contemporary coalescent theory, which describes the genealogy of genes in a population, ultimately connecting them to a single common ancestor. Effects of selection, particularly genomic effects, are discussed with reference to molecular genetic variation. The book is designed for students of population genetics, bioinformatics, evolutionary biology, molecular evolution, and theoretical biology--as well as biologists, molecular biologists, breeders, biomathematicians, and biostatisticians. Contains up-to-date treatment of key areas in classical and modern theoretical population genetics Provides in-depth coverage of coalescent theory Discusses genomic effects of selection Gives examples from empirical population genetics Incorporates figures, diagrams, and boxed features throughout Includes end-of-chapter exercises Speaks to a wide range of students in biology, bioinformatics, and biostatistics

The Genetic Lottery

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Publisher : Princeton University Press
ISBN 13 : 0691190801
Total Pages : 312 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis The Genetic Lottery by : Kathryn Paige Harden

Download or read book The Genetic Lottery written by Kathryn Paige Harden and published by Princeton University Press. This book was released on 2021-09-21 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: A provocative and timely case for how the science of genetics can help create a more just and equal society In recent years, scientists like Kathryn Paige Harden have shown that DNA makes us different, in our personalities and in our health—and in ways that matter for educational and economic success in our current society. In The Genetic Lottery, Harden introduces readers to the latest genetic science, dismantling dangerous ideas about racial superiority and challenging us to grapple with what equality really means in a world where people are born different. Weaving together personal stories with scientific evidence, Harden shows why our refusal to recognize the power of DNA perpetuates the myth of meritocracy, and argues that we must acknowledge the role of genetic luck if we are ever to create a fair society. Reclaiming genetic science from the legacy of eugenics, this groundbreaking book offers a bold new vision of society where everyone thrives, regardless of how one fares in the genetic lottery.

Frontiers in the Nutrition Sciences

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Publisher : National Academies Press
ISBN 13 : 0309041465
Total Pages : 241 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Frontiers in the Nutrition Sciences by : Institute of Medicine

Download or read book Frontiers in the Nutrition Sciences written by Institute of Medicine and published by National Academies Press. This book was released on 1989-02-01 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series of individually authored chapters examines the nature and extent of scientific advances in the nutrition sciences and describes both future opportunities in the field and barriers to progress. Despite concern about declining attention to nutrition in universities and medical schools, the authors offer a bright and challenging future in nutrition research and training that should generate enthusiasm among young researchers and teachers for this indispensable component of biology.

Homology Molecular Modeling

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Publisher : BoD – Books on Demand
ISBN 13 : 1839628057
Total Pages : 147 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Homology Molecular Modeling by : Rafael Trindade Maia

Download or read book Homology Molecular Modeling written by Rafael Trindade Maia and published by BoD – Books on Demand. This book was released on 2021-03-10 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homology modeling is an extremely useful and versatile technique that is gaining more and more space and demand in research in computational and theoretical biology. This book, “Homology Molecular Modeling - Perspectives and Applications”, brings together unpublished chapters on this technique. In this book, 7 chapters are intimately related to the theme of molecular modeling, carefully selected and edited for academic and scientific readers. It is an indispensable read for anyone interested in the areas of bioinformatics and computational biology. Divided into 4 sections, the reader will have a didactic and comprehensive view of the theme, with updated and relevant concepts on the subject. This book was organized from researchers to researchers with the aim of spreading the fascinating area of molecular modeling by homology.

Virus as Populations

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Publisher : Academic Press
ISBN 13 : 0128163321
Total Pages : 428 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Virus as Populations by : Esteban Domingo

Download or read book Virus as Populations written by Esteban Domingo and published by Academic Press. This book was released on 2019-11-06 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. - Features current views on key steps in the origin of life and origins of viruses - Includes examples relating ancestral features of viruses with their current adaptive capacity - Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read - Considers quasispecies as a framework to understand virus adaptability and disease processes

A Companion to Anthropological Genetics

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Publisher : John Wiley & Sons
ISBN 13 : 111876899X
Total Pages : 496 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis A Companion to Anthropological Genetics by : Dennis H. O'Rourke

Download or read book A Companion to Anthropological Genetics written by Dennis H. O'Rourke and published by John Wiley & Sons. This book was released on 2019-03-19 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore the latest research in anthropological genetics and understand the genome’s role in cultural and social development A Companion to Anthropological Genetics illustrates the role of genetic analysis in advancing the modern study of human origins, populations, evolution, and diversity. Broad in scope, this essential reference work establishes and explores the relationship between genetic research and the major questions of anthropological study. Through contributions by leading researchers, this collection explores molecular genetics and evolutionary mechanisms in the context of macro- and microevolution, paleontology, phylogeny, diet, and disease, with detailed explanations of quantitative methods, including coalescent and approximate Bayesian computation. With an emphasis on contextualizing new and developing genetic research within anthropological frameworks, this text offers critical perspective on the conditions of molecular evolution that accompany cultural and social transformation, while also addressing critical disciplinary questions, such as the ethical issues surrounding ancestry testing and community-based genetic research. Acts as an essential reference on the contributions of genetic science to the field of anthropology Features new work by leading researchers of the field Explores the evolution of immunity, including the genetics and epigenetics of pathogens, chronic illness, and disease resistance Provides in-depth examination of mutation and dietary adaptation, including AMY1, lactase persistence, and sensory polymorphisms Explains essential quantitative and phylogenetic methods for aligning genomic analysis with evolution and migration time scales Offering thorough coverage on leading questions and developing research, A Companion to Anthropological Genetics is a comprehensive resource for students and scholars.

Mutants

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Publisher : Penguin
ISBN 13 : 1101562765
Total Pages : 449 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Mutants by : Armand Marie Leroi

Download or read book Mutants written by Armand Marie Leroi and published by Penguin. This book was released on 2005-01-25 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Visit Armand Marie Leroi on the web: http://armandleroi.com/index.html Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it—a French convent girl who found herself changing sex at puberty; children who, echoing Homer’s Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity. This elegant, humane, and engaging book “captures what we know of the development of what makes us human” (Nature).