Fractionation In Radiotherapy

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Practical Radiation Oncology

Author : Supriya Mallick
Publisher : Springer Nature
ISBN 13 : 9811500738
Total Pages : 282 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Practical Radiation Oncology by : Supriya Mallick

Download or read book Practical Radiation Oncology written by Supriya Mallick and published by Springer Nature. This book was released on 2019-11-25 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the most relevant aspects of radiation oncology in terms of technical integrity, dose parameters, machine and software specifications, as well as regulatory requirements. Radiation oncology is a unique field that combines physics and biology. As a result, it has not only a clinical aspect, but also a physics aspect and biology aspect, all three of which are inter-related and critical to optimal radiation treatment planning. In addition, radiation oncology involves a host of machines/software. One needs to have a firm command of these machines and their specifications to deliver comprehensive treatment. However, this information is not readily available, which poses serious challenges for students learning the planning aspect of radiation therapy. In response, this book compiles these relevant aspects in a single source. Radiation oncology is a dynamic field, and is continuously evolving. However, tracking down the latest findings is both difficult and time-consuming. Consequently, the book also comprehensively covers the most important trials. Offering an essential ready reference work, it represents a value asset for all radiation oncology practitioners, trainees and students.

Fractionation in Radiotherapy

Author : Howard D. Thames
Publisher : CRC Press
ISBN 13 : 9780850663747
Total Pages : 297 pages
Book Rating : 4.6/5 (637 download)

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Book Synopsis Fractionation in Radiotherapy by : Howard D. Thames

Download or read book Fractionation in Radiotherapy written by Howard D. Thames and published by CRC Press. This book was released on 1987-07-01 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Topics in Clinical Radiobiology of Tumors

Author : Hans-Peter Beck-Bornholdt
Publisher : Springer Science & Business Media
ISBN 13 : 3642849180
Total Pages : 364 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Current Topics in Clinical Radiobiology of Tumors by : Hans-Peter Beck-Bornholdt

Download or read book Current Topics in Clinical Radiobiology of Tumors written by Hans-Peter Beck-Bornholdt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The impact of basic science radiobiological research is now being recognized of significant importance in clinical radiation oncology. Observations made in the laboratory using animals as'well as tissue culture have led to a better biologic understanding of techniques for altered fractionation, techniques for measuring tumor cell proliferation, the possi bilities and limitations of methods for evaluation of nonrandomized clinical studies in deriving time dose relationships for human tumors as well as a better understanding of repair kinetics in mammalian cells, fractionation sensitivity and the major impact oftechnologies to improve local/regional control with the subsequent impact on survival. These findings have led to changes in treatment schedules and have led to further close cooperation among the radiation oncologists and radiation biologists. Well support research efforts in radiation biology have a major and significant impact on the clinical care of the cancer patient. Studies that originated in the laboratory are now finding their way into clinical practice resulting in better local and regional control and improved number of patients surviving without disease.

Stereotactic Body Radiation Therapy

Author : Simon S. Lo
Publisher : Springer Science & Business Media
ISBN 13 : 364225604X
Total Pages : 433 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Stereotactic Body Radiation Therapy by : Simon S. Lo

Download or read book Stereotactic Body Radiation Therapy written by Simon S. Lo and published by Springer Science & Business Media. This book was released on 2012-08-28 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.

Hypofractionated and Stereotactic Radiation Therapy

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Author : Orit Kaidar-Person
Publisher : Springer
ISBN 13 : 3319928023
Total Pages : 404 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Hypofractionated and Stereotactic Radiation Therapy by : Orit Kaidar-Person

Download or read book Hypofractionated and Stereotactic Radiation Therapy written by Orit Kaidar-Person and published by Springer. This book was released on 2018-07-31 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook summarizes the data and techniques for hypofractionation and stereotactic radiation in a clinically-accessible way. Hypofractionated radiation therapy, which consists of larger-dose radiation treatments that are given over a shorter time period compared to conventional radiation fraction sizes, is used to treat a variety of cancers, including prostate, breast, lung, and colorectal. Conventional radiation therapy and hypofractionated radiation therapy have different effectiveness rates for cancer treatment and have different impacts on normal tissues in terms of causing toxicity. There is a significant and growing body of literature on the use of different dosing regimens to treat a variety of cancers and radiation oncologists need to keep up with the various dosing schedules, the effect of each regimen on cancer control in different cancers, and how the different schedules affect each organ in terms of toxicity. The book thus provides concise information ranging from commonly-used dose-fractionation schemes for hypofractionated and stereotactic body radiotherapy to simulation and treatment specifications to published safety and efficacy data. Chapters additionally examine the biological rationales for the efficacy of hypofractionated radiation; present clinical studies that demonstrate the efficacy and safety of hypofractionated radiation treatment in a variety of cancers; and describe the advances in technology that have allowed hypofractionated radiation to be safely given. This is an ideal guide for radiation oncology clinicians and trainees.

Radiobiology for the Radiologist

Author : Eric J. Hall
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451154186
Total Pages : 908 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Radiobiology for the Radiologist by : Eric J. Hall

Download or read book Radiobiology for the Radiologist written by Eric J. Hall and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt: In print since 1972, this seventh edition of Radiobiology for the Radiologist is the most extensively revised to date. It consists of two sections, one for those studying or practicing diagnostic radiolo, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia. Now in full color, this lavishly illustrated new edition is replete with tables and figures that underscore essential concepts. Each chapter concludes with a "summary of pertinent conclusions" to facilitate quick review and help readers retain important information.

Alternate Fractionation in Radiotherapy

Author : Mark Trombetta
Publisher : Springer
ISBN 13 : 331951198X
Total Pages : 413 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Alternate Fractionation in Radiotherapy by : Mark Trombetta

Download or read book Alternate Fractionation in Radiotherapy written by Mark Trombetta and published by Springer. This book was released on 2018-09-25 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, written by leading international experts, describes alternate fractionation strategies in which technology-driven precise targeting and dosing allow for improved conformance and decreased volumes, with concordant lessening of toxicity, reduction in treatment time, and lower overall health care expense. The aim is to provide the advanced clinician with an up-to-date evidence-based reference that will assist in the delivery of enhanced patient care in daily practice. Traditional multi-week fractionation schedules were established at a time when the inclusion of relatively large amounts of normal tissue was unavoidable owing to the lack of accurate target localization during treatment. Such schedules are time and resource consuming, difficult for patients, and expensive. Nevertheless, acceptance of alternate fractionation strategies has been slow in some countries. The paradigm is, however, changing as evidence accumulates to demonstrate improved local control, equivalence of tolerance, or both. In documenting these alternate strategies, this book will be of value for radiation oncologists, medical physicists, and oncologists worldwide.

Re-Irradiation: New Frontiers

Author : Carsten Nieder
Publisher : Springer
ISBN 13 : 3319418254
Total Pages : 368 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Re-Irradiation: New Frontiers by : Carsten Nieder

Download or read book Re-Irradiation: New Frontiers written by Carsten Nieder and published by Springer. This book was released on 2016-10-25 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid to the exciting developments in the fields of proton irradiation and frameless image-guided ablative radiotherapy. The book documents fully how refined combined modality approaches and significant technical advances in radiation treatment planning and delivery have facilitated the re-irradiation of previously exposed volumes, allowing both palliative and curative approaches to be pursued at various disease sites. Professionals involved in radiation treatment planning and multimodal oncology treatment will find it to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.

Basic Clinical Radiobiology

Author : Michael C. Joiner
Publisher : CRC Press
ISBN 13 : 0429955405
Total Pages : 361 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Basic Clinical Radiobiology by : Michael C. Joiner

Download or read book Basic Clinical Radiobiology written by Michael C. Joiner and published by CRC Press. This book was released on 2018-08-28 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Builds on success and reputation of previous editions Draws on the considerable teaching experience of an international author team, most notably the US and European Editors The gold-standard European text for training, adopted by ESTRO as a course book, as a text for the Royal College of Radiologists' radiobiology exam and by courses in the US Highly illustrated with new, 2 colour illustrations Clear and concise style, appropriate for trainees and also practising radiation oncologists requiring a ready reference to the subject Includes new chapters on stem cells, tissue response and the meeting point of meeting point of radiotherapy, radiobiology and physics

IASLC Thoracic Oncology E-Book

Author : Harvey Pass
Publisher : Elsevier Health Sciences
ISBN 13 : 0323527841
Total Pages : 960 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis IASLC Thoracic Oncology E-Book by : Harvey Pass

Download or read book IASLC Thoracic Oncology E-Book written by Harvey Pass and published by Elsevier Health Sciences. This book was released on 2017-04-21 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global experts, in conjunction with the International Association for the Study of Lung Cancer, bring you up to date with today’s best approaches to lung cancer diagnosis, treatment, and follow-up. IASLC Thoracic Oncology, 2nd Edition, keeps you abreast of the entire scope of this fast-changing field, from epidemiology to diagnosis to treatment to advocacy. Written in a straightforward, practical style for the busy clinician, this comprehensive, multidisciplinary title is a must-have for anyone involved in the care of patients with lung cancer and other thoracic malignancies. Offers practical, relevant coverage of basic science, epidemiology, pulmonology, medical and radiation oncology, surgery, pathology, palliative care, nursing, and advocacy. Provides authoritative guidance from the IASLC – the only global organization dedicated to the study of lung cancer. Includes new content on molecular testing, immunotherapy, early detection, staging and the IASLC staging system, surgical resection for stage I and stage II lung cancer, and stem cells in lung cancer. Features a new full-color design throughout, as well as updated diagnostic algorithms.

Biomedical Physics in Radiotherapy for Cancer

Author : Barry Allen
Publisher : CSIRO PUBLISHING
ISBN 13 : 0643103317
Total Pages : 449 pages
Book Rating : 4.6/5 (431 download)

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Book Synopsis Biomedical Physics in Radiotherapy for Cancer by : Barry Allen

Download or read book Biomedical Physics in Radiotherapy for Cancer written by Barry Allen and published by CSIRO PUBLISHING. This book was released on 2012-02-21 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific and clinical foundations of Radiation Therapy are cross-disciplinary. This book endeavours to bring together the physics, the radiobiology, the main clinical aspects as well as available clinical evidence behind Radiation Therapy, presenting mutual relationships between these disciplines and their role in the advancements of radiation oncology.

Textbook of Radiation Oncology

Author : Steven A. Leibel
Publisher :
ISBN 13 : 9780721600260
Total Pages : 0 pages
Book Rating : 4.6/5 (2 download)

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Book Synopsis Textbook of Radiation Oncology by : Steven A. Leibel

Download or read book Textbook of Radiation Oncology written by Steven A. Leibel and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, the 2nd Edition presents all of the latest advances in the field, including the most recent technologies and techniques. For each tumor site discussed, readers will find unparalleled coverage of multiple treatment plans, histology and biology of the tumor, its anatomic location and routes of spread, and utilization of specialized techniques. This convenient source also reviews all of the basic principles that underlie the selection and application of radiation as a treatment modality, including radiobiology, radiation physics, immobilization and simulation, high dose rate, intraoperative irradation, and more. Comprehensively reviews each topic, with a distinct clinical orientation throughout. Serves as a foundation for the basic principles that underlie the selection and application of radiation as a treatment modality, including radiobiology, radiation physics, immobilization and simulation, high dose rate, intraoperative irradation, and more. Guides readers through all stages of treatment application with step-by-step techniques for the assessment and implementation of radiotherapeutic options. Presents latest information on brachytherapy * 3-dimensional conformal treatment planning * sterotactic radiosurgery * and radiolabeled antibodies. Discusses the recent use of radiotherapy in the treatment of primary lymphoma, leukemia, multiple myeloma, and cancers of the prostate and central nervous system. Includes the latest AJCC staging system guidelines. Offers the latest advances in techniques, allowing you to deliver doses precisely to areas affected by malignancy and spare healthy tissue. Presents new chapters on the hottest topics including Three Dimensional Conformal Radiotherapy * Intensity Modulated Radiotherapy * Breathing Synchronized Radiotherapy * Plasma Cell Tumors: Multiple Myeloma and Solitary Plasmacytoma * Extracranial Stereotactic Radioablation * and [Imaging of the] Head and Neck * Thorax * Abdomen * and Pelvis.

Optimal Fractionation in Radiotherapy with Multiple Normal Tissues

Author : Fatemeh Saberian
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (137 download)

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Book Synopsis Optimal Fractionation in Radiotherapy with Multiple Normal Tissues by : Fatemeh Saberian

Download or read book Optimal Fractionation in Radiotherapy with Multiple Normal Tissues written by Fatemeh Saberian and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal in radiotherapy is to maximize the biological effect of radiation on the tumor while limiting its toxic effects on healthy anatomies. Treatment is administered over several sessions to give the normal tissue time to recover as it has better damage repair capabilities than tumor cells. This is termed fractionation. A key problem in radiotherapy involves finding an optimal number of treatment sessions (fractions) and the corresponding dosing schedule. A major limitation of existing mathematically rigorous work on this problem is that it includes only a single normal tissue. Since essentially no anatomical region of interest includes only one normal tissue, these models may incorrectly identify the optimal number of fractions and the corresponding dosing schedule. We present a formulation of the optimal fractionation problem that includes multiple normal tissues. Our model can tackle any combination of maximum dose, mean dose, and dose-volume type constraints for serial and parallel normal tissues as this is characteristic of most treatment protocols. We also allow for a spatially heterogeneous dose distribution within each normal tissue. Furthermore, we do not a priori assume that the doses are invariant across fractions. Finally, our model uses a spatially optimized treatment plan as input and hence can be seamlessly combined with any treatment planning system. Our formulation is a mixed-integer, noncovex, quadratically constrained quadratic program. In order to simplify this computationally challenging problem without loss of optimality, we establish suffcient conditions under which equal-dosage or single-dosage fractionation is optimal. Based on the prevalent estimates of tumor and normal tissue model parameters, these conditions are expected to hold in many types of commonly studied tumors, such as those similar to head- and-neck and prostate cancers. This motivates a simple reformulation of our problem that leads to a closed-form formula for the dose per fraction. We then establish that the tumor biological effect is quasiconcave in the number of fractions; this ultimately helps in identifying the optimal number of fractions. We perform extensive numerical experiments using ten head-and-neck and prostate test cases to uncover several clinically relevant insights.

Cancer of the Head and Neck

Author : William S. MacComb
Publisher :
ISBN 13 :
Total Pages : 624 pages
Book Rating : 4.:/5 (5 download)

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Book Synopsis Cancer of the Head and Neck by : William S. MacComb

Download or read book Cancer of the Head and Neck written by William S. MacComb and published by . This book was released on 1967 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Equine Oncology

Author : Derek C. Knottenbelt
Publisher : Saunders
ISBN 13 : 9780702042669
Total Pages : 0 pages
Book Rating : 4.0/5 (426 download)

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Book Synopsis Clinical Equine Oncology by : Derek C. Knottenbelt

Download or read book Clinical Equine Oncology written by Derek C. Knottenbelt and published by Saunders. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnose common equine tumors accurately and find clinical information quickly! Clinical Equine Oncology describes the cellular basis of cancer and its etiopathogenesis, along with the principles of diagnosis, treatment, and management of cancer cases. This comprehensive resource offers more than just facts and diagrams - hundreds of detailed photographs make it easier to recognize and evaluate more than 50 types of tumors. It's useful to anyone working in the equine field, whether you're a veterinary surgeon, a practicing vet, equine dentist, or veterinary student. Written by a recognized expert on equine medicine, Derek Knottenbelt, this is the only book on the market that is completely dedicated to coverage of cancer in horses! More than 50 different types of tumor are covered, including tumors that occur in each of the 10 body systems. Over 800 excellent-quality photographs show the appearance of pathologies and cancerous conditions both before and after treatment. More than 80 full-color diagrams summarize key information. Detailed Pathology section describes common neoplasms in horses, cites research literature, and describes what is generally known about each condition. Authoritative, inclusive, and unique coverage is likely to remain the standard reference for years to come. Expert authors are recognized as the top experts in the field of equine oncology. Practical, colorful design includes icon-based references for quick appraisal of prevalence and prognosis.

Spine Radiosurgery

Author : Peter Gerszten
Publisher : Thieme
ISBN 13 : 1626230358
Total Pages : 634 pages
Book Rating : 4.6/5 (262 download)

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Book Synopsis Spine Radiosurgery by : Peter Gerszten

Download or read book Spine Radiosurgery written by Peter Gerszten and published by Thieme. This book was released on 2015-08-19 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spine Radiosurgery, Second Edition , is a comprehensive text that includes discussions of the latest devices, treatment planning techniques, target definition, and patient selection in this specialty. Written by leading experts in the fields of neurosurgery, radiation oncology, and medical physics, this book is the definitive reference for clinical applications of state-of-the-art radiosurgery of the spine. Key Features: Six new chapters on such topics as histopathological examination of spinal lesions, minimally invasive techniques, and treatment of spinal chordomas More than 100 full-color illustrations demonstrate key concepts Discussion of new treatments for metastatic spine disease and spinal cord compression This book is a must-have resource for clinicians, fellows, and residents in neurosurgery and radiation oncology. Spine surgeons, orthopaedists, medical physicists, and oncologists at all levels will also benefit from the wealth of information provided.

Accelerated Partial Breast Irradiation

Author : Douglas W. Arthur
Publisher : Springer
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Accelerated Partial Breast Irradiation by : Douglas W. Arthur

Download or read book Accelerated Partial Breast Irradiation written by Douglas W. Arthur and published by Springer. This book was released on 2006-05-23 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a concise handbook designed to assist the clinician in the implementation of Accelerated Partial Breast Irradiation (APBI). It includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications. The book encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation.