Forensic Dna Typing

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DNA Technology in Forensic Science

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309045878
Total Pages : 199 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis DNA Technology in Forensic Science by : National Research Council

Download or read book DNA Technology in Forensic Science written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Matching DNA samples from crime scenes and suspects is rapidly becoming a key source of evidence for use in our justice system. DNA Technology in Forensic Science offers recommendations for resolving crucial questions that are emerging as DNA typing becomes more widespread. The volume addresses key issues: Quality and reliability in DNA typing, including the introduction of new technologies, problems of standardization, and approaches to certification. DNA typing in the courtroom, including issues of population genetics, levels of understanding among judges and juries, and admissibility. Societal issues, such as privacy of DNA data, storage of samples and data, and the rights of defendants to quality testing technology. Combining this original volume with the new update-The Evaluation of Forensic DNA Evidence-provides the complete, up-to-date picture of this highly important and visible topic. This volume offers important guidance to anyone working with this emerging law enforcement tool: policymakers, specialists in criminal law, forensic scientists, geneticists, researchers, faculty, and students.

Forensic DNA Typing

Author : John M. Butler
Publisher : Elsevier
ISBN 13 : 9780080470610
Total Pages : 688 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Forensic DNA Typing by : John M. Butler

Download or read book Forensic DNA Typing written by John M. Butler and published by Elsevier. This book was released on 2005-02-08 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic DNA Typing, Second Edition, is the only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome. It examines the science of current forensic DNA typing methods by focusing on the biology, technology, and genetic interpretation of short tandem repeat (STR) markers, which encompass the most common forensic DNA analysis methods used today. The book covers topics from introductory level right up to cutting edge research. High-profile cases are addressed throughout the text, near the sections dealing with the science or issues behind these cases. Ten new chapters have been added to accommodate the explosion of new information since the turn of the century. These additional chapters cover statistical genetic analysis of DNA data, an emerging field of interest to DNA research. Several chapters on statistical analysis of short tandem repeat (STR) typing data have been contributed by Dr. George Carmody, a well-respected professor in forensic genetics. Specific examples make the concepts of population genetics more understandable. This book will be of interest to researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories (for identifying individuals through remains), and students of forensic science. *The only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome *Chapters cover the topic from introductory level right up to "cutting edge" research *High-profile cases are addressed throughout the book, near the sections dealing with the science or issues behind these cases *NEW TO THIS EDITION: D.N.A. Boxes--boxed "Data, Notes & Applications" sections throughout the book offer higher levels of detail on specific questions

Fundamentals of Forensic DNA Typing

Author : John M. Butler
Publisher : Academic Press
ISBN 13 : 0080961762
Total Pages : 519 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Fundamentals of Forensic DNA Typing by : John M. Butler

Download or read book Fundamentals of Forensic DNA Typing written by John M. Butler and published by Academic Press. This book was released on 2009-09-30 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980’s, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key

Advanced Topics in Forensic DNA Typing: Interpretation

Author : John M. Butler
Publisher : Academic Press
ISBN 13 : 012405854X
Total Pages : 608 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Advanced Topics in Forensic DNA Typing: Interpretation by : John M. Butler

Download or read book Advanced Topics in Forensic DNA Typing: Interpretation written by John M. Butler and published by Academic Press. This book was released on 2014-07-28 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Topics in Forensic DNA Typing: Interpretation builds upon the previous two editions of John Butler’s internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. Intended as a third-edition companion to the Fundamentals of Forensic DNA Typing volume published in 2010 and Advanced Topics in Forensic DNA Typing: Methodology published in 2012, this book contains 16 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field. Over 80 % of the content of this book is new compared to previous editions. Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence Worked mixture examples illustrate the impact of different statistical approaches for reporting results Includes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011

Nonhuman DNA Typing

Author : Heather Miller Coyle
Publisher : CRC Press
ISBN 13 : 1040079881
Total Pages : 193 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Nonhuman DNA Typing by : Heather Miller Coyle

Download or read book Nonhuman DNA Typing written by Heather Miller Coyle and published by CRC Press. This book was released on 2007-08-29 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: The association of a suspect with the victim or crime scene through DNA evidence is one of the most powerful statements of complicity in a crime imaginable. No category of evidence has ever had the complete capacity to convict or exonerate an accused so absolutely in the eyes of the public. With the discriminatory powers of DNA and the variety of D

The Evaluation of Forensic DNA Evidence

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309121949
Total Pages : 271 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Evaluation of Forensic DNA Evidence by : National Research Council

Download or read book The Evaluation of Forensic DNA Evidence written by National Research Council and published by National Academies Press. This book was released on 1997-01-12 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.

Forensic DNA Typing: Principles, Applications and Advancements

Author : Pankaj Shrivastava
Publisher : Springer Nature
ISBN 13 : 9811566550
Total Pages : 673 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Forensic DNA Typing: Principles, Applications and Advancements by : Pankaj Shrivastava

Download or read book Forensic DNA Typing: Principles, Applications and Advancements written by Pankaj Shrivastava and published by Springer Nature. This book was released on 2020-12-11 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book explores the fundamental principles, advances in forensic techniques, and its application on forensic DNA analysis. The book is divided into three modules; the first module provides the historical prospect of forensic DNA typing and introduces fundamentals of forensic DNA typing, methodology, and technical advancements, application of STRs, and DNA databases for forensic DNA profile analysis. Module 2 examines the problems and challenges encountered in extracting DNA and generating DNA profiles. It provides information on the methods and the best practices for DNA isolation from forensic biological samples and human remains like ancient DNA, DNA typing of skeletal remains and disaster victim identification, the importance of DNA typing in human trafficking, and various problems associated with capillary electrophoresis. Module 3 emphasizes various technologies that are based on SNPs, STRs namely Y-STR, X-STR, mitochondrial DNA profiling in forensic science. Module 4 explores the application of non-human forensic DNA typing of domestic animals, wildlife forensics, plant DNA fingerprinting, and microbial forensics. The last module discusses new areas and alternative methods in forensic DNA typing, including Next-Generation Sequencing, and its utility in forensic science, oral microbes, and forensic DNA phenotyping. Given its scope, the book is a useful resource in the field of DNA fingerprinting for scientists, forensic experts, and students at the postgraduate level.

Forensic DNA Biology

Author : Kelly M. Elkins
Publisher : Academic Press
ISBN 13 : 0123945852
Total Pages : 226 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Forensic DNA Biology by : Kelly M. Elkins

Download or read book Forensic DNA Biology written by Kelly M. Elkins and published by Academic Press. This book was released on 2012-09-11 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of forensic DNA typing laboratory experiments designed for academic and training courses at the collegiate level.

Forensic DNA Typing Protocols

Author : Angel Carracedo
Publisher : Springer Science & Business Media
ISBN 13 : 1592598676
Total Pages : 282 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Forensic DNA Typing Protocols by : Angel Carracedo

Download or read book Forensic DNA Typing Protocols written by Angel Carracedo and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art collection of readily reproducible laboratory methods for DNA identity analysis, including Y chromosome haplotyping, mtDNA, and SNP typing. The book offers well-tested protocols for DNA quantification using real-time PCR on forensic samples and for the determination of the number of amelogenine gene copies. For forensic geneticists, there are readily reproducible methods for species identification, ancient DNA, and pharmacogenetics. Additional chapters address new applications in the forensic genetics lab, such a species identification or typing of CYP polymorphisms for the analysis of adverse to drugs.

Forensic DNA Evidence Interpretation, Second Edition

Author : John S. Buckleton
Publisher : CRC Press
ISBN 13 : 1482258927
Total Pages : 496 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Forensic DNA Evidence Interpretation, Second Edition by : John S. Buckleton

Download or read book Forensic DNA Evidence Interpretation, Second Edition written by John S. Buckleton and published by CRC Press. This book was released on 2016-04-21 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, Forensic DNA Evidence Interpretation is the most comprehensive resource for DNA casework available today. Written by leaders in the fields of biology and statistics, including a contribution from Peter Gill, the father of DNA analysis, the book emphasizes the interpretation of test results and provides the necessary formulae in an easily accessible manner. This latest edition is fully updated and includes current and emerging techniques in this fast-moving field. The book begins by reviewing all pertinent biology, and then provides information on every aspect of DNA analysis. This includes modern interpretation methods and contemporary population genetic models available for estimating DNA frequencies or likelihood ratios. Following a chapter on procedures for validating databases, the text presents overviews and performance assessments of both modern sampling uncertainty methods and current paternity testing techniques, including new guidelines on paternity testing in alignment with the International Society for Forensic Genetics. Later chapters discuss the latest methods for mixture analysis, LCN (ultra trace) analysis and non-autosomal (mito, X, and Y) DNA analysis. The text concludes with an overview of procedures for disaster victim identification and information on DNA intelligence databases. Highlights of the second edition include: New information about PCR processes, heterozygote balance and back and forward stuttering New information on the interpretation of low template DNA, drop models and continuous models Additional coverage of lineage marker subpopulation effects, mixtures and combinations with autosomal markers This authoritative book provides a link among the biological, forensic, and interpretative domains of the DNA profiling field. It continues to serve as an invaluable resource that allows forensic scientists, technicians, molecular biologists and attorneys to use forensic DNA evidence to its greatest potential.

Forensic DNA Profiling Protocols

Author : Patrick J. Lincoln
Publisher : Springer Science & Business Media
ISBN 13 : 0896034437
Total Pages : 617 pages
Book Rating : 4.8/5 (96 download)

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Book Synopsis Forensic DNA Profiling Protocols by : Patrick J. Lincoln

Download or read book Forensic DNA Profiling Protocols written by Patrick J. Lincoln and published by Springer Science & Business Media. This book was released on 1998-01-22 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of-the-art collection of easily reproducible methods includes all of the major techniques of DNA analysis currently used in forensic identity testing. The methods include the recovery of DNA from a large range of sample types, analysis of DNA as single and multi-locus VNTR probes, PCR amplification of STR and other loci, and mitochondrial sequencing. The expert scientists writing here -- many from laboratories around the world -- also discuss how to interpret the results in cases of unknown identity and disputed parentage.-- Covers all steps from extraction of human DNA through to analysis and interpretation-- Takes advantage of new methodologies such as capillary electrophoresis-- Clear step-by-step instructions ensure unfailing reproducibility.

Forensic Analysis of Biological Evidence

Author : J. Thomas McClintock
Publisher : CRC Press
ISBN 13 : 1466504587
Total Pages : 176 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Forensic Analysis of Biological Evidence by : J. Thomas McClintock

Download or read book Forensic Analysis of Biological Evidence written by J. Thomas McClintock and published by CRC Press. This book was released on 2017-08-02 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: A powerful tool in the identification of individuals, DNA typing has revolutionized criminal and paternity investigations. Widespread analysis is now conducted by public and private laboratories in the United States and abroad. Focusing on the basic techniques used in forensic DNA laboratories, Forensic Analysis of Biological Evidence: A Laboratory

Forensic DNA Applications

Author : Dragan Primorac
Publisher : CRC Press
ISBN 13 : 1466580224
Total Pages : 652 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Forensic DNA Applications by : Dragan Primorac

Download or read book Forensic DNA Applications written by Dragan Primorac and published by CRC Press. This book was released on 2014-01-29 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic DNA Applications: An Interdisciplinary Perspective was developed as an outgrowth of a conference held by the International Society of Applied Biological Sciences. The topic was human genome–based applications in forensic science, anthropology, and individualized medicine. Assembling the contributions of contributors from numerous regions around the world, this volume is designed as both a textbook for forensic molecular biology students and a reference for practitioners and those in the legal system. The book begins with the history and development of DNA typing and profiling for criminal and civil purposes. It discusses the statistical interpretation of results with case examples, mitochondrial DNA testing, Y single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs), and X SNP and STR testing. It also explores low copy number DNA typing, mixtures, and quality assurance and control. The second section examines the collection and preservation of biological evidence under a variety of different circumstances and the identification of human remains—including in mass disaster settings. It discusses applications to bioterrorism investigations, animal DNA testing in criminal cases, pedigree questions and wildlife forensic problems, applications in forensic entomology, and forensic botany. The third section explores recent developments and new technologies, including the rigorous identification of tissue of origin, mtDNA profiling using immobilized probe strips, chips and next-generation sequencing, the use of SNPs to ascertain phenotypic characteristics, and the "molecular autopsy" that looks at aspects of toxicogenetics and pharmacogenetics. The book concludes with a discussion on law, ethics, and policy. It examines the use of DNA evidence in the criminal justice system in both the United States and Europe, ethical issues in forensic laboratory practices, familial searches, DNA databases, ancestry searches, physical phenotyping, and report writing. The contributors also examine DNA applications in immigration and human trafficking cases and international perspectives on DNA databases.

Forensic DNA Analysis

Author : J. Thomas McClintock
Publisher : CRC Press
ISBN 13 : 1420063308
Total Pages : 178 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Forensic DNA Analysis by : J. Thomas McClintock

Download or read book Forensic DNA Analysis written by J. Thomas McClintock and published by CRC Press. This book was released on 2008-02-19 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its short but active history, the use of DNA typing has revolutionized criminal investigations. It is almost inconceivable to bring a case to trial without positive identification through what is now our most accurate means. Proficiency with the methodology, principles, and interpretation of DNA evidence is crucial for today‘s criminalist.

Forensic DNA Profiling

Author : Jo-Anne Bright
Publisher : CRC Press
ISBN 13 : 0429671423
Total Pages : 132 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Forensic DNA Profiling by : Jo-Anne Bright

Download or read book Forensic DNA Profiling written by Jo-Anne Bright and published by CRC Press. This book was released on 2019-12-09 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA testing and its forensic analysis are recognized as the “gold standard” in forensic identification science methods. However, there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a likelihood ratio, and how to use the subsequent likelihood ratio when reporting interpretation conclusions. Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately, many crime scene profiles are not single source. They are described as mixed since they contain DNA from two or more individuals. Interpretation of DNA mixtures represents one of the greatest challenges to the forensic DNA analyst. As such, the book introduces terms used to describe DNA profiles and profile interpretation. Chapters explain DNA extraction methods, the polymerase chain reaction (PCR), capillary electrophoresis (CE), likelihood ratios (LRs) and their interpretation, and population genetic models—including Mendelian inheritance and Hardy-Weinberg equilibrium. It is important that analysts understand how LRs are generated in a probabilistic framework, ideally with an appreciation of both semicontinuous and fully continuous probabilistic approaches. KEY FEATURES: • The first book to focus entirely on DNA mixtures and the complexities involved with interpreting the results • Takes a hands-on approach offering theory with worked examples and exercises to be easily understood and implementable by laboratory personnel • New methods, heretofore unpublished previously, provide a means to innovate deconvoluting a mixed DNA profile, assign an LR, and appropriately report the weight of evidence • Includes a chapter on assigning LRs for close relatives (i.e., “It’s not me, it was my brother”), and discusses strategies for the validation of probabilistic genotyping software Forensic DNA Profiling fills the void for labs unfamiliar with LRs, and moving to probabilistic solutions, and for labs already familiar with LRs, but wishing to understand how they are calculated in more detail. The book will be a welcome read for lab professionals and technicians, students, and legal professionals seeking to understand and apply the techniques covered.

Wildlife DNA Analysis

Author : Adrian Linacre
Publisher : John Wiley & Sons
ISBN 13 : 1118496523
Total Pages : 360 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Wildlife DNA Analysis by : Adrian Linacre

Download or read book Wildlife DNA Analysis written by Adrian Linacre and published by John Wiley & Sons. This book was released on 2013-03-27 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clearly structured throughout, the introduction highlights the different types of crime where these techniques are regularly used. This chapter includes a discussion as to who performs forensic wildlife examinations, the standardisation and validation of methods, and the role of the expert witness in this type of alleged crime. This is followed by a detailed section on the science behind DNA typing including the problems in isolating DNA from trace material and subsequent genetic analysis are also covered. The book then undertakes a comprehensive review of species testing using DNA, including a step-by-step guide to sequence comparisons. A comparison of the different markers used in species testing highlights the criteria for a genetic marker. A full set of case histories illustrates the use of the different markers used. The book details the use of genetic markers to link two or more hairs/feather/leaves/needles to the same individual organism and the software used in population assignment. The problems and possibilities in isolating markers, along with the construction of allele databases are discussed in this chapter. The book concludes with evaluation and reporting of genetic evidence in wildlife forensic science illustrated by examples of witness statements.

Inside the Cell

Author : Erin E. Murphy
Publisher : Bold Type Books
ISBN 13 : 1568584695
Total Pages : 400 pages
Book Rating : 4.5/5 (685 download)

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Book Synopsis Inside the Cell by : Erin E. Murphy

Download or read book Inside the Cell written by Erin E. Murphy and published by Bold Type Books. This book was released on 2015-10-06 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: a version less likely to play out on dramatic television shows. In Inside the Cell, Erin Murphy shows how DNA typing can be subject to misuse, mistake, and error, and lead to a police state run amok. Murphy shows the perils of a society in which "stop-and-frisk" becomes "stop-and-spit," or in which police pose undercover to get a DNA sample from your discarded lunch. Already, police can collect DNA when making an arrest, sometimes before charging a person with a crime. The government is building a massive DNA database, stockpiling samples from as much as a third of the male population, and the laws regulating what they can and cannot do with them are weak. Murphy shows how this invites the riskiest kind of genetic surveillance imaginable. Just because DNA testing is good science does not mean that it is foolproof. Faulty forensic science is the number two factor leading to wrongful conviction, and yet we have done little to improve the use of science in criminal justice.