Fluoxetine

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Listening to Prozac

Author : Peter D. Kramer
Publisher : Penguin
ISBN 13 : 0140266712
Total Pages : 481 pages
Book Rating : 4.1/5 (42 download)

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Book Synopsis Listening to Prozac by : Peter D. Kramer

Download or read book Listening to Prozac written by Peter D. Kramer and published by Penguin. This book was released on 1997-09-01 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New York Times bestselling examination of the revolutionary antidepressant, with a new introduction and afterword reflecting on Prozac’s legacy and the latest medical research “Peter Kramer is an analyst of exceptional sensitivity and insight. To read his prose on virtually any subject is to be provoked, enthralled, illuminated.” —Joyce Carol Oates When antidepressants like Prozac first became available, Peter D. Kramer prescribed them, only to hear patients say that on medication, they felt different—less ill at ease, more like the person they had always imagined themselves to be. Referencing disciplines from cellular biology to animal ethology, Dr. Kramer worked to explain these reports. The result was Listening to Prozac, a revolutionary book that offered new perspectives on antidepressants, mood disorders, and our understanding of the self—and that became an instant national and international bestseller. In this thirtieth anniversary edition, Dr. Kramer looks back at the influence of his groundbreaking book, traces progress in the relevant sciences, follows trends in the use and public understanding of antidepressants, and assesses potential breakthroughs in the treatment of depression. The new introduction and afterword reinforce and reinvigorate a book that the New York Times called “originally insightful” and “intelligent and informative,” a window on a medicine that is “telling us new things about the chemistry of human character.”

Drug-Induced Liver Injury

Author :
Publisher : Academic Press
ISBN 13 : 0128173173
Total Pages : 288 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug-Induced Liver Injury by :

Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Fluoxetine

Author : Graziano Pinna
Publisher :
ISBN 13 : 9781634820769
Total Pages : 412 pages
Book Rating : 4.8/5 (27 download)

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Book Synopsis Fluoxetine by : Graziano Pinna

Download or read book Fluoxetine written by Graziano Pinna and published by . This book was released on 2015-04-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluoxetine, best known by the trade name Prozac®, unlike other psychotropic drugs whose effects were serendipitously stumbled upon, was the first developed for a precise mechanism of action, that is, the ability to selectively inhibit serotonin reuptake, based upon the theory that increasing the availability of serotonin would treat major depression. Once approved by the FDA in 1987, fluoxetine quickly became the most prescribed psychotropic drug worldwide and its success in improving mood disorders has triggered the development of a large number of congener molecules, commonly known as SSRIs after their purported mechanism of action. However, a quarter of a century after its development, the idea that fluoxetine asserts its positive behavioral effect through inhibition of serotonergic reuptake is not firmly established. This book reviews several preclinical and clinical reports suggesting that the pharmacological effects of fluoxetine may be mediated by means other than the regulation of serotonin, including the regulation of gene expression, modifying epigenetic mechanisms as well as modifying microRNAs. One of the most prominent mechanisms for the therapeutic relevance of fluoxetine relates to influencing neuroplasticity by enhancing neurotropic factors, including BDNF signaling and altering adult neurogenesis. The ability of fluoxetine to rapidly increase neurosteroid levels accounts for the fast anxiolytic effects of this drug. Fluoxetine action at sigma-1 receptor or modulating glutamatergic neurotransmission as well as the combination of fluoxetine with other psychotropic drugs is discussed in relation to its therapeutic effects. While fluoxetine was primarily prescribed as an antidepressant, this drug currently represents a treatment of choice for a broad spectrum of psychiatric disorders, including post-traumatic stress disorder and a range of anxiety disorders. This drug even possesses analgesic actions and is a valuable therapy for stroke. This book also highlights emerging evidence on the gender-specific effects of fluoxetine, its potential adverse features, including its addiction liability in combination with psychostimulants, and the impact of perinatal fluoxetine exposure.

Let Them Eat Prozac

Author : David Healy
Publisher : NYU Press
ISBN 13 : 0814736971
Total Pages : 367 pages
Book Rating : 4.8/5 (147 download)

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Book Synopsis Let Them Eat Prozac by : David Healy

Download or read book Let Them Eat Prozac written by David Healy and published by NYU Press. This book was released on 2006-10 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: A psychiatrist provides an insider account on the controversial use of selective serotonin reuptake inhibitors (SSRIs) Prozac. Paxil. Zoloft. Turn on your television and you are likely to see a commercial for one of the many selective serotonin reuptake inhibitors (SSRIs) on the market. We hear a lot about them, but do we really understand how these drugs work and what risks are involved for anyone who uses them? Let Them Eat Prozac explores the history of SSRIs—from their early development to their latest marketing campaigns—and the controversies that surround them. Initially, they seemed like wonder drugs for those with mild to moderate depression. When Prozac was released in the late 1980s, David Healy was among the psychiatrists who prescribed it. But he soon observed that some of these patients became agitated and even attempted suicide. Could the new wonder drug actually be making patients worse? Healy draws on his own research and expertise to demonstrate the potential hazards associated with these drugs. He intersperses case histories with insider accounts of the research leading to the development and approval of SSRIs as a treatment for depression. Let Them Eat Prozac clearly demonstrates that the problems go much deeper than a side-effect of a particular drug. The pharmaceutical industry would like us to believe that SSRIs can safely treat depression, anxiety, and a host of other mental problems. But, as Let Them Eat Prozac reveals, this “cure” may be worse than the disease.

Davis's Drug Guide for Rehabilitation Professionals

Author : Charles D. Ciccone
Publisher : F.A. Davis
ISBN 13 : 0803640048
Total Pages : 1217 pages
Book Rating : 4.8/5 (36 download)

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Book Synopsis Davis's Drug Guide for Rehabilitation Professionals by : Charles D. Ciccone

Download or read book Davis's Drug Guide for Rehabilitation Professionals written by Charles D. Ciccone and published by F.A. Davis. This book was released on 2013-03-21 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!

Synthesis of Essential Drugs

Author : Ruben Vardanyan
Publisher : Elsevier
ISBN 13 : 9780080462127
Total Pages : 634 pages
Book Rating : 4.4/5 (621 download)

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Book Synopsis Synthesis of Essential Drugs by : Ruben Vardanyan

Download or read book Synthesis of Essential Drugs written by Ruben Vardanyan and published by Elsevier. This book was released on 2006-03-10 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO’s Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types * Includes synonyms * Includes over 2300 references

Pain Review E-Book

Author : Steven D. Waldman
Publisher : Elsevier Health Sciences
ISBN 13 : 0323481655
Total Pages : 765 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Pain Review E-Book by : Steven D. Waldman

Download or read book Pain Review E-Book written by Steven D. Waldman and published by Elsevier Health Sciences. This book was released on 2016-09-22 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easy to read and easy to use, Pain Review, 2nd Edition provides you with the most up-to-date, comprehensive review of pain medicine available. Written by Steven Waldman, MD, a leading author in the specialty of pain medicine, this book gives you exactly what you need – an easily understandable, targeted review of the essential basic science; beautifully illustrated, full-color anatomic figures; and a comprehensive review of common and uncommon pain syndromes, as well as how-to-do-it explanations of all of the pain management injection and nerve block techniques that every practitioner needs to know. Pain Review, 2nd Edition is an excellent tool for reviewing the specialty and for preparing for your pain medicine board review, recertification, or for the practice of pain medicine. Provides the reader with clearly written review of the signs, symptoms and physical findings of 95 defined pain syndromes classified by body region. Presents an easy-to-follow, generously illustrated, step-by step roadmap of how to perform 113 individual nerve blocks and injection techniques, as well as a review of associated pitfalls and complications. Follows an easy-to-read templated format throughout for quick mastery and retrieval of information, closely matching the format and content of the American Board of Anesthesiology pain medicine board certification exam. Maintains a consistent approach and editorial style as a single-authored text by noted authority Steven D. Waldman, MD. NEW! Conceptual illustrations are now in full color to help you better visualize injection techniques. Hundreds of NEW full color tables and figures simplify learning. NEW, updated design offers visual appeal and ease of use. Updated references throughout direct you to the most up-to-date source material.

Hepatotoxicity

Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781719520
Total Pages : 848 pages
Book Rating : 4.7/5 (195 download)

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Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman

Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Epigenetics in Psychiatry

Author : Jacob Peedicayil
Publisher : Academic Press
ISBN 13 : 0128235780
Total Pages : 848 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Epigenetics in Psychiatry by : Jacob Peedicayil

Download or read book Epigenetics in Psychiatry written by Jacob Peedicayil and published by Academic Press. This book was released on 2021-08-21 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent advances in epigenetic understanding of psychiatric disorders, evoking data consortia (e.g., CommonMind, ATAC-seq), single cell analysis, and epigenome-wide association studies to empower new research. The book also examines epigenetic effects of the microbiome on psychiatric disorders, and the use of neuroimaging in studying the role of epigenetic mechanisms of gene expression. Ongoing advances in epigenetic therapy are explored in-depth. Fully revised to discuss new areas of research across neuronal stem cells, cognitive disorders, and transgenerational epigenetics in psychiatric disease Relates broad advances in psychiatric epigenetics to a modern understanding of the genome, transcriptome, and proteins Catalyzes knowledge discovery in both basic epigenetic biology and epigenetic targets for drug discovery Provides guidance in research methods and protocols, as well how to employ data from consortia, single cell analysis, and epigenome-wide association studies (EWAS) Features chapter contributions from international leaders in the field

Body Dysmorphic Disorder

Author : Dr Katharine Phillips
Publisher : Oxford University Press
ISBN 13 : 0190254157
Total Pages : 608 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Body Dysmorphic Disorder by : Dr Katharine Phillips

Download or read book Body Dysmorphic Disorder written by Dr Katharine Phillips and published by Oxford University Press. This book was released on 2017-07-12 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: This landmark book is the first comprehensive edited volume on body dysmorphic disorder (BDD), a common and severe disorder. People with BDD are preoccupied with distressing or impairing preoccupations with non-existent or slight defects in their physical appearance. People with BDD think that they look ugly -- even monstrous -- although they look normal to others. BDD often derails sufferers' lives and can lead to suicide. BDD has been described around the world since the 1800s but was virtually unknown and unstudied until only several decades ago. Since then, research on BDD has dramatically increased understanding of this often-debilitating condition. Only recently, BDD was considered untreatable, but today, most sufferers can be successfully treated. This is the only book that provides comprehensive, in-depth, up-to-date information on BDD's clinical features, history, classification, epidemiology, morbidity, features in special populations, diagnosis and assessment, etiology and pathophysiology, treatment, and relationship to other disorders. Numerous chapters focus on cosmetic treatment, because it is frequently received but usually ineffective for BDD, which can lead to legal action and even violence toward treating clinicians. The book includes numerous clinical cases, which illustrate BDD's clinical features, its often-profound consequences, and recommended treatment approaches. This volume's contributors are the leading researchers and clinicians in this rapidly expanding field. Editor Katharine A. Phillips, head of the DSM-V committee on BDD, has done pioneering research on many aspects of this disorder, including its treatment. This book will be of interest to all clinicians who provide mental health treatment and to researchers in BDD, anxiety disorders, eating disorders, and other obsessive-compulsive and related disorders. It will be indispensable to surgeons, dermatologists, and other clinicians who provide cosmetic treatment. Students and trainees with an interest in psychology and mental health will also be interested in this book. This book fills a major gap in the literature by providing clinicians and researchers with cutting-edge, indispensable information on all aspects of BDD and its treatment.

Prozac Backlash

Author : Joseph Glenmullen
Publisher : Simon and Schuster
ISBN 13 : 0743200624
Total Pages : 388 pages
Book Rating : 4.7/5 (432 download)

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Book Synopsis Prozac Backlash by : Joseph Glenmullen

Download or read book Prozac Backlash written by Joseph Glenmullen and published by Simon and Schuster. This book was released on 2001-04-17 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a controversial look at the potent drugs millions of Americans consume each day--for everything from anxiety to sexual addiction--Dr. Glenmullen presents authoritative information on why they are risky and provides advice on choosing safer alternative treatments.

Drugs, Driving and Traffic Safety

Author : Joris C. Verster
Publisher : Springer Science & Business Media
ISBN 13 : 3764399236
Total Pages : 564 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Drugs, Driving and Traffic Safety by : Joris C. Verster

Download or read book Drugs, Driving and Traffic Safety written by Joris C. Verster and published by Springer Science & Business Media. This book was released on 2009-08-29 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs, Driving and Traffic Safety gives a comprehensive overview of the effects of different medical conditions like neurological disorders, anxiety and depression and their pharmaceutical treatment on driving ability. In addition, the effects of alcohol and drugs of abuse are discussed. Leading experts present the different methodologies to examine effects of drugs on driving, and summarize the recent scientific evidence including epidemiological studies, roadside surveys, laboratory tests, driving simulators, and the standardized driving test. The volume includes guidelines of the International Council on Alcohol, Drugs and Traffic Safety (ICADTS) and the ICADTS Drugs List 2007. Drugs, Driving and Traffic Safety is written for physicians, psychiatrists and pharmacists who want to inform their patients who use psychoactive drugs.

Clinical Psychopharmacology

Author : Nassir Ghaemi
Publisher : Oxford University Press, USA
ISBN 13 : 0199995486
Total Pages : 601 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Clinical Psychopharmacology by : Nassir Ghaemi

Download or read book Clinical Psychopharmacology written by Nassir Ghaemi and published by Oxford University Press, USA. This book was released on 2019-01-04 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Psychopharmacology offers a comprehensive guide to clinical practice that explores two major aspects of the field: the clinical research that exists to guide clinical practice of psychopharmacology, and the application of that knowledge with attention to the individualized aspects of clinical practice. The text consists of 50 chapters, organized into 6 sections, focusing on disease-modifying effects, non-DSM diagnostic concepts, and essential facts about the most common drugs. This innovative book advocates a scientific and humanistic approach to practice and examines not only the benefits, but also the harms of drugs. Providing a solid foundation of knowledge and a great deal of practical information, this book is a valuable resource for practicing psychiatrists, psychiatric nurse practitioners, medical students and trainees in psychiatry, as well as pharmacists.

Drug-Induced Liver Disease

Author : Neil Kaplowitz
Publisher : CRC Press
ISBN 13 : 0203909127
Total Pages : 784 pages
Book Rating : 4.2/5 (39 download)

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Book Synopsis Drug-Induced Liver Disease by : Neil Kaplowitz

Download or read book Drug-Induced Liver Disease written by Neil Kaplowitz and published by CRC Press. This book was released on 2002-10-16 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.

Prozac Nation

Author : Elizabeth Wurtzel
Publisher : HarperCollins
ISBN 13 : 0547524145
Total Pages : 384 pages
Book Rating : 4.5/5 (475 download)

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Book Synopsis Prozac Nation by : Elizabeth Wurtzel

Download or read book Prozac Nation written by Elizabeth Wurtzel and published by HarperCollins. This book was released on 2014-11-04 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Elizabeth Wurtzel's New York Times best-selling memoir, with a new afterword "Sparkling, luminescent prose . . . A powerful portrait of one girl's journey through the purgatory of depression and back." —New York Times "A book that became a cultural touchstone." —New Yorker Elizabeth Wurtzel writes with her finger on the faint pulse of an overdiagnosed generation whose ruling icons are Kurt Cobain, Xanax, and pierced tongues. Her famous memoir of her bouts with depression and skirmishes with drugs, Prozac Nation is a witty and sharp account of the psychopharmacology of an era for readers of Girl, Interrupted and Sylvia Plath’s The Bell Jar.

The Antidepressant Fact Book

Author : Peter Breggin
Publisher : Da Capo Press
ISBN 13 : 0786741821
Total Pages : 240 pages
Book Rating : 4.7/5 (867 download)

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Book Synopsis The Antidepressant Fact Book by : Peter Breggin

Download or read book The Antidepressant Fact Book written by Peter Breggin and published by Da Capo Press. This book was released on 2009-04-20 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Known as "the Ralph Nader of psychiatry," Dr. Peter Breggin has been the medical expert in countless court cases involving the use or misuse of psychoactive medications. This unusual position has given him unprecedented access to private pharmaceutical research and correspondence files, information from which informs this straight-talking guide to the most prescribed and controversial category of American drugs: antidepressants. From how these drugs work in the brain to how they treat (or don't treat) depression and obsessive-compulsive, panic, and other disorders; from the documented side and withdrawal effects to what every parent needs to know about antidepressants and teenagers, The Anti-Depressant Fact Book is up-to-the minute and easy-to-access. Hard-hitting and enlightening, every current, former, and prospective antidepressant-user will want to read this book.

Talking Back to Prozac

Author : Peter R. Breggin
Publisher : Open Road Media
ISBN 13 : 1497617480
Total Pages : 373 pages
Book Rating : 4.4/5 (976 download)

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Book Synopsis Talking Back to Prozac by : Peter R. Breggin

Download or read book Talking Back to Prozac written by Peter R. Breggin and published by Open Road Media. This book was released on 2014-04-01 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: A psychiatrist takes a critical look at this SSRI and newer medications that are among the most frequently prescribed drugs in America. Prozac. Millions of Americans are on it. And just about everyone else is wondering if they should be on it, too. The claims of the pro‐Prozac chorus are enticing: that it can cure everything from depression (the only disorder for which Prozac was originally approved) to fear of public speaking, PMS, obesity, shyness, migraine, and back pain—with few or no side effects. But is the reality quite different? At what price do we buy Prozac‐induced euphoria and a shiny new personality? Psychiatrist Peter Breggin, MD, and coauthor Ginger Ross Breggin answer these and other crucial questions in Talking Back to Prozac. They explain what Prozac is and how it works, and they take a hard look at the real story behind today’s most controversial drug: The fact that Prozac was tested in trials of four to six weeks in length before receiving FDA approval The difficulty Prozac’s manufacturer had in proving its effectiveness during these tests The information on side effects that the FDA failed to include in its final labeling requirements How Prozac acts as a stimulant not unlike the addictive drugs cocaine and amphetamine The dangers of possible Prozac addiction and abuse The seriousness and frequency of Prozac’s side effects, including agitation, insomnia, nausea, diarrhea, loss of libido, and difficulty reaching orgasm The growing evidence that Prozac can cause violence and suicide The social and workplace implications of using the drug not to cure depression but to change personality and enhance performance Using dramatic case histories as well as scientific research and carefully documented evidence, the Breggins expose the potentially damaging effects of Prozac. They also describe the resounding success that has been achieved with more humane alternatives for the treatment of depression. Talking Back to Prozac provides essential information for anyone who takes Prozac or is considering taking it, and for those who prescribe it.